| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N Aguirre, D Frechilla, A García-Osta, B Lasheras, J Del Rí. Differential regulation by methylenedioxymethamphetamine of 5-hydroxytryptamine1A receptor density and mRNA expression in rat hippocampus, frontal cortex, and brainstem: the role of corticosteroids. Journal of neurochemistry. vol 68. issue 3. 1997-04-07. PMID:9048755. |
adrenalectomy by itself did not modify 5-ht content in the brain regions examined and increased 5-ht1a receptor density in the hippocampus (+20%) but produced no change in the frontal cortex and brainstem. |
1997-04-07 |
2023-08-12 |
rat |
| A Gobert, J M Rivet, L Cistarelli, M J Milla. Potentiation of the fluoxetine-induced increase in dialysate levels of serotonin (5-HT) in the frontal cortex of freely moving rats by combined blockade of 5-HT1A and 5-HT1B receptors with WAY 100,635 and GR 127,935. Journal of neurochemistry. vol 68. issue 3. 1997-04-07. PMID:9048762. |
potentiation of the fluoxetine-induced increase in dialysate levels of serotonin (5-ht) in the frontal cortex of freely moving rats by combined blockade of 5-ht1a and 5-ht1b receptors with way 100,635 and gr 127,935. |
1997-04-07 |
2023-08-12 |
rat |
| A Gobert, J M Rivet, L Cistarelli, M J Milla. Potentiation of the fluoxetine-induced increase in dialysate levels of serotonin (5-HT) in the frontal cortex of freely moving rats by combined blockade of 5-HT1A and 5-HT1B receptors with WAY 100,635 and GR 127,935. Journal of neurochemistry. vol 68. issue 3. 1997-04-07. PMID:9048762. |
the selective 5-ht1a antagonist way 100,635 (0.16 mg/kg, s.c.) did not influence 5-ht release alone but doubled the influence of fluoxetine on basal levels. |
1997-04-07 |
2023-08-12 |
rat |
| A Gobert, J M Rivet, L Cistarelli, M J Milla. Potentiation of the fluoxetine-induced increase in dialysate levels of serotonin (5-HT) in the frontal cortex of freely moving rats by combined blockade of 5-HT1A and 5-HT1B receptors with WAY 100,635 and GR 127,935. Journal of neurochemistry. vol 68. issue 3. 1997-04-07. PMID:9048762. |
the present data demonstrate that combined blockade of 5-ht1a and 5-ht1b autoreceptors markedly and selectively potentiates the fluoxetine-induced increase in dialysate levels of 5-ht versus da and nad in the fcx of freely moving rats. |
1997-04-07 |
2023-08-12 |
rat |
| J R Moiseiwitsch, J M Laude. Regulation of gene expression in cultured embryonic mouse mandibular mesenchyme by serotonin antagonists. Anatomy and embryology. vol 195. issue 1. 1997-04-04. PMID:9006717. |
the differential effects of antagonists suggest that in vivo, 5-ht could: (1) promote expression of cartilage core protein by activation of 5-ht3 or 5-ht1a receptors, (2) inhibit production of tenascin by activation of multiple receptors, (3) promote or inhibit synthesis of s-100 beta by activation of 5-ht3 or 5-ht2 receptors, respectively. |
1997-04-04 |
2023-08-12 |
mouse |
| I Malagié, A C Trillat, E Douvier, M C Anmella, M C Dessalles, C Jacquot, A M Gardie. Regional differences in the effect of the combined treatment of WAY 100635 and fluoxetine: an in vivo microdialysis study. Naunyn-Schmiedeberg's archives of pharmacology. vol 354. issue 6. 1997-04-02. PMID:8971740. |
we studied the changes in extracellular serotonin (5-ht) levels in the frontal cortex (fc) and ventral hippocampus (vhi) in conscious rats, induced by the combined administration of a highly selective 5-ht1a receptor antagonist, way 100635 (0.1 mg/kg, i.v. |
1997-04-02 |
2023-08-12 |
rat |
| T A Lutz, E Del Prete, B Walzer, E Scharre. The histaminergic, but not the serotoninergic, system mediates amylin's anorectic effect. Peptides. vol 17. issue 8. 1997-04-02. PMID:8971926. |
similarly, inhibition of 5-ht synthesis and release with the 5-ht1a receptor agonist (+/-)-8-hydroxy-2-(di-n-propylamino)tetralin hydrobromide (200 micrograms/kg, ip) did not diminish amylin's (5 micrograms/kg, ip) anorectic effect in 24-h food-deprived rats whereas that of cck (3 micrograms/kg, ip) was blocked under comparable conditions. |
1997-04-02 |
2023-08-12 |
rat |
| F F Matos, C Korpinen, F D Yocc. 5-HT1A receptor agonist effects of BMY-14802 on serotonin release in dorsal raphe and hippocampus. European journal of pharmacology. vol 317. issue 1. 1997-04-02. PMID:8982718. |
5-ht1a receptor agonist effects of bmy-14802 on serotonin release in dorsal raphe and hippocampus. |
1997-04-02 |
2023-08-12 |
rat |
| F F Matos, C Korpinen, F D Yocc. 5-HT1A receptor agonist effects of BMY-14802 on serotonin release in dorsal raphe and hippocampus. European journal of pharmacology. vol 317. issue 1. 1997-04-02. PMID:8982718. |
the 5-ht decreases in dorsal raphe and hippocampus produced by bmy-14802 were completely antagonized by pretreatment with 1.0 mg/kg of the specific 5-ht1a antagonist, way-100635 (n-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-n-(2-pyridinyl) cyclohexanecarboxamide trihydrochloride). |
1997-04-02 |
2023-08-12 |
rat |
| F F Matos, C Korpinen, F D Yocc. 5-HT1A receptor agonist effects of BMY-14802 on serotonin release in dorsal raphe and hippocampus. European journal of pharmacology. vol 317. issue 1. 1997-04-02. PMID:8982718. |
these data indicate that bmy-14802 decreases dorsal raphe and hippocampal release of 5-ht by interaction with somatodendritic 5-ht1a receptors in the raphe nuclei and suggest that this compound is a potential anxiolytic. |
1997-04-02 |
2023-08-12 |
rat |
| M Maes, E Vandoolaeghe, R Desnyde. Efficacy of treatment with trazodone in combination with pindolol or fluoxetine in major depression. Journal of affective disorders. vol 41. issue 3. 1997-04-02. PMID:8988452. |
chronic treatment with both drugs causes increases in extracellular 5-ht through 5-ht reuptake inhibition and desensitization of inhibitory 5-ht1a autoreceptors. |
1997-04-02 |
2023-08-12 |
Not clear |
| F Marrosu, C A Fornal, C W Metzler, B L Jacob. 5-HT1A agonists induce hippocampal theta activity in freely moving cats: role of presynaptic 5-HT1A receptors. Brain research. vol 739. issue 1-2. 1997-04-01. PMID:8955939. |
our results suggest that preferential activation of presynaptic 5-ht1a receptors, and subsequent inhibition of serotonin neurotransmission, facilitates the appearance of hippocampal theta activity in awake cats. |
1997-04-01 |
2023-08-12 |
Not clear |
| S L Lee, W W Wang, B L Fanbur. Association of Tyr phosphorylation of GTPase-activating protein with mitogenic action of serotonin. The American journal of physiology. vol 272. issue 1 Pt 1. 1997-03-28. PMID:9038828. |
in the presence of 3-isobutyl-1-methylxanthine, 5-ht inhibited cellular growth, presumably through its action on 5-ht1a or 5-ht4 receptors and elevation of adenosine 3',5'-cyclic monophosphate, but this was not associated with an alteration of tyr phosphorylation of gap. |
1997-03-28 |
2023-08-12 |
Not clear |
| A Dugar, J M Lakosk. Serotonergic function of aging hippocampal CA3 pyramidal neurons: electrophysiological assessment following administration of 5,7-dihydroxytryptamine in the fimbria-fornix and cingulum bundle. Journal of neuroscience research. vol 47. issue 1. 1997-03-26. PMID:8981238. |
vehicle (ascorbic saline) or 5,7-dht was administered bilaterally in the fimbria-fornix/cingulum bundle and dorsal pyramidal cell responses to microiontophoretic application of 5-ht, the 5-ht1a agonist (+/-)-8-hydroxy-2-(di-n-propylamino) tetralin, the 5-ht1a antagonist way 100,135 and n-methyl-d-aspartate were recorded at 3 weeks post-lesion. |
1997-03-26 |
2023-08-12 |
rat |
| A El Manira, W Zhang, E Svensson, N Bussière. 5-HT inhibits calcium current and synaptic transmission from sensory neurons in lamprey. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 5. 1997-03-26. PMID:9030637. |
the inhibition of monosynaptic epsps by 5-ht was not counteracted by an antagonist of 5-ht1a receptors. |
1997-03-26 |
2023-08-12 |
Not clear |
| A H Lau, G D Fry. Acute and chronic actions of ethanol on CA1 hippocampal responses to serotonin. Brain research. vol 731. issue 1-2. 1997-03-25. PMID:8883849. |
5-ht (1-100 microm) caused concentration-dependent hyperpolarization of the membrane that was not altered by simultaneous 30 mm ethanol treatment, but blunted by 10 microm buspirone, a weak 5-ht1a agonist. |
1997-03-25 |
2023-08-12 |
rat |
| R S Mansbach, C C Rovetti, J E Maco. CP-135,807, a selective 5-HT1D agonist: effects in drug discrimination and punishment procedures in the pigeon. Psychopharmacology. vol 128. issue 3. 1997-03-24. PMID:8972551. |
in contrast, little substitution was observed following administration of 8-oh-dpat, a potent 5-ht1a agonist, the 5-ht1b agonist cp-94,253, or the serotonin reuptake inhibitor sertraline. |
1997-03-24 |
2023-08-12 |
human |
| S Hjorth, H J Bengtsson, S Milan. Raphe 5-HT1A autoreceptors, but not postsynaptic 5-HT1A receptors or beta-adrenoceptors, restrain the citalopram-induced increase in extracellular 5-hydroxytryptamine in vivo. European journal of pharmacology. vol 316. issue 1. 1997-03-21. PMID:8982649. |
raphe 5-ht1a autoreceptors, but not postsynaptic 5-ht1a receptors or beta-adrenoceptors, restrain the citalopram-induced increase in extracellular 5-hydroxytryptamine in vivo. |
1997-03-21 |
2023-08-12 |
rat |
| S Hjorth, H J Bengtsson, S Milan. Raphe 5-HT1A autoreceptors, but not postsynaptic 5-HT1A receptors or beta-adrenoceptors, restrain the citalopram-induced increase in extracellular 5-hydroxytryptamine in vivo. European journal of pharmacology. vol 316. issue 1. 1997-03-21. PMID:8982649. |
in vivo microdialysis in rat ventral hippocampus was used (i) to verify the importance of 5-ht1a autoreceptors in the raphe as targets for drugs that enhance the citalopram-induced elevation of forebrain 5-hydroxytryptamine (5-ht), and (ii) to further examine the specificity of (-)-penbutolol in this regard. |
1997-03-21 |
2023-08-12 |
rat |
| S Hjorth, H J Bengtsson, S Milan. Raphe 5-HT1A autoreceptors, but not postsynaptic 5-HT1A receptors or beta-adrenoceptors, restrain the citalopram-induced increase in extracellular 5-hydroxytryptamine in vivo. European journal of pharmacology. vol 316. issue 1. 1997-03-21. PMID:8982649. |
the selective 5-ht1a receptor antagonist way100635 (s.c., or intra-raphe) or the mixed 5-ht1a/1b/beta-adrenoceptor antagonist (-)-penbutolol (s.c.), potentiated the citalopram-induced 5-ht rise, whereas local "reverse' dialysis of way100635 into the ventral hippocampus did not. |
1997-03-21 |
2023-08-12 |
rat |