| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Hjorth, H J Bengtsson, S Milan. Raphe 5-HT1A autoreceptors, but not postsynaptic 5-HT1A receptors or beta-adrenoceptors, restrain the citalopram-induced increase in extracellular 5-hydroxytryptamine in vivo. European journal of pharmacology. vol 316. issue 1. 1997-03-21. PMID:8982649. |
the selective 5-ht1a receptor antagonist way100635 (s.c., or intra-raphe) or the mixed 5-ht1a/1b/beta-adrenoceptor antagonist (-)-penbutolol (s.c.), potentiated the citalopram-induced 5-ht rise, whereas local "reverse' dialysis of way100635 into the ventral hippocampus did not. |
1997-03-21 |
2023-08-12 |
rat |
| S Hjorth, H J Bengtsson, S Milan. Raphe 5-HT1A autoreceptors, but not postsynaptic 5-HT1A receptors or beta-adrenoceptors, restrain the citalopram-induced increase in extracellular 5-hydroxytryptamine in vivo. European journal of pharmacology. vol 316. issue 1. 1997-03-21. PMID:8982649. |
these data provide direct evidence that increased stimulation of 5-ht1a autoreceptors in the midbrain raphe impedes the effect of citalopram on forebrain extracellular 5-ht, whereas neither postsynaptic 5-ht1a receptors nor beta-adrenoceptors appear to be involved. |
1997-03-21 |
2023-08-12 |
rat |
| A M Laporte, C Doyen, I T Nevo, J Chauveau, J J Hauw, M Hamo. Autoradiographic mapping of serotonin 5-HT1A, 5-HT1D, 5-HT2A and 5-HT3 receptors in the aged human spinal cord. Journal of chemical neuroanatomy. vol 11. issue 1. 1997-03-20. PMID:8841890. |
autoradiographic mapping of serotonin 5-ht1a, 5-ht1d, 5-ht2a and 5-ht3 receptors in the aged human spinal cord. |
1997-03-20 |
2023-08-12 |
human |
| A M Laporte, C Doyen, I T Nevo, J Chauveau, J J Hauw, M Hamo. Autoradiographic mapping of serotonin 5-HT1A, 5-HT1D, 5-HT2A and 5-HT3 receptors in the aged human spinal cord. Journal of chemical neuroanatomy. vol 11. issue 1. 1997-03-20. PMID:8841890. |
quantitative autoradiography with selective radioligands was used to establish the respective distribution of serotonin 5-ht1a, 5-ht1d, 5-ht2a and 5-ht3 receptors at the cervical, thoracic and lumbar levels of the spinal cord from subjects who died at 81-94 years. |
1997-03-20 |
2023-08-12 |
human |
| L Romero, I Hervás, F Artiga. The 5-HT1A antagonist WAY-100635 selectively potentiates the presynaptic effects of serotonergic antidepressants in rat brain. Neuroscience letters. vol 219. issue 2. 1997-03-20. PMID:8971795. |
the increases in extracellular serotonin (5-hydroxytryptamine; 5-ht) produced by some antidepressent drugs in forebrain are attenuated by the activation of somatodendritic 5-ht1a autoreceptors by the excess 5-ht induced by these agents in the midbrain raphe. |
1997-03-20 |
2023-08-12 |
rat |
| L Romero, I Hervás, F Artiga. The 5-HT1A antagonist WAY-100635 selectively potentiates the presynaptic effects of serotonergic antidepressants in rat brain. Neuroscience letters. vol 219. issue 2. 1997-03-20. PMID:8971795. |
using microdialysis, we have examined the effects of the selective 5-ht1a antagonist way-100635 in rats pretreated with the selective 5-ht reuptake inhibitors (ssris) citalopram, fluoxetine, fluvoxamine, the tricyclic antidepressants clomipramine and desipramine and the monoamine oxidase inhibitor phenelzine. |
1997-03-20 |
2023-08-12 |
rat |
| L Romero, N Bel, J M Casanovas, F Artiga. Two actions are better than one: avoiding self-inhibition of serotonergic neurones enhances the effects of serotonin uptake inhibitors. International clinical psychopharmacology. vol 11 Suppl 4. 1997-03-19. PMID:8923121. |
the excess 5-ht produced by these antidepressant drugs in the interstitial space of the midbrain raphe activates somatodendritic 5-ht1a autoreceptors, thereby attenuating terminal 5-ht release. |
1997-03-19 |
2023-08-12 |
Not clear |
| L Romero, N Bel, J M Casanovas, F Artiga. Two actions are better than one: avoiding self-inhibition of serotonergic neurones enhances the effects of serotonin uptake inhibitors. International clinical psychopharmacology. vol 11 Suppl 4. 1997-03-19. PMID:8923121. |
in keeping with these observations, the combined administration of selective serotonin reuptake inhibitors (ssris) and 5-ht1a antagonists increase the cortical and striatal extracellular 5-ht concentration more than the former alone. |
1997-03-19 |
2023-08-12 |
Not clear |
| T Moriya, S Yamanouchi, T Fukushima, T Shimazoe, S Shibata, S Watanab. Involvement of 5-HT1A receptor mechanisms in the inhibitory effects of methamphetamine on photic responses in the rodent suprachiasmatic nucleus. Brain research. vol 740. issue 1-2. 1997-03-19. PMID:8973823. |
we examined the role of serotonin 1a (5-ht1a) receptors in the inhibitory effects of methamphetamine (ma) on photic entrainment to the circadian pacemaker in the suprachiasmatic nucleus (scn) of rodents. |
1997-03-19 |
2023-08-12 |
Not clear |
| T Moriya, S Yamanouchi, T Fukushima, T Shimazoe, S Shibata, S Watanab. Involvement of 5-HT1A receptor mechanisms in the inhibitory effects of methamphetamine on photic responses in the rodent suprachiasmatic nucleus. Brain research. vol 740. issue 1-2. 1997-03-19. PMID:8973823. |
these findings suggest that elevation of endogenous 5-ht levels by ma inhibits the photic entraining responses of the circadian pacemaker in the scn via 5-ht1a receptor stimulation of the 5-ht released by ma. |
1997-03-19 |
2023-08-12 |
Not clear |
| E Davids, K P Lesc. [The 5-HT1A receptor: a new effective principle in psychopharmacologic therapy?]. Fortschritte der Neurologie-Psychiatrie. vol 64. issue 11. 1997-03-18. PMID:9064274. |
as the beta-adrenoceptor blockers show also affinities to other 5-ht receptors than the 5-ht1a receptor the recently discovered more selective 5-ht1a antagonists became of interest. |
1997-03-18 |
2023-08-12 |
Not clear |
| b' H K Kia, M J Brisorgueil, M Hamon, A Calas, D Verg\\xc3\\xa. Ultrastructural localization of 5-hydroxytryptamine1A receptors in the rat brain. Journal of neuroscience research. vol 46. issue 6. 1997-03-17. PMID:8978504.' |
these data suggest that the action of serotonin via 5-ht1a receptor could occur through junctional as well as nonjunctional transmission. |
1997-03-17 |
2023-08-12 |
rat |
| J Lladó, S Esteban, J A García-Sevill. The alpha 2-adrenoceptor antagonist idazoxan is an agonist at 5-HT1A autoreceptors modulating serotonin synthesis in the rat brain in vivo. Neuroscience letters. vol 218. issue 2. 1997-03-14. PMID:8945740. |
the alpha 2-adrenoceptor antagonist idazoxan is an agonist at 5-ht1a autoreceptors modulating serotonin synthesis in the rat brain in vivo. |
1997-03-14 |
2023-08-12 |
rat |
| J Lladó, S Esteban, J A García-Sevill. The alpha 2-adrenoceptor antagonist idazoxan is an agonist at 5-HT1A autoreceptors modulating serotonin synthesis in the rat brain in vivo. Neuroscience letters. vol 218. issue 2. 1997-03-14. PMID:8945740. |
the results indicate that idazoxan is a potent and specific agonist at 5-ht1a autoreceptors modulating brain serotonin synthesis in vivo. |
1997-03-14 |
2023-08-12 |
rat |
| N N Kudriavtseva, T G Amstislavskaia, D F Avgustinovich, I V Bakshtanovskaia, T V Lipina, O V Gorbach, L A Koriakin. [The effect of the repeated experience of victories and defeats in social conflicts on the function of the brain serotoninergic system in male mice]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 46. issue 6. 1997-03-13. PMID:9054161. |
serotonin (5-ht) and 5-hydroxyindoleacetic acid (5-hiaa) levels, tryptophan hydroxylase (tph) activity, and 5-ht1a receptor binding were studied in brain areas of male mice after repeated experience of victories (winners) and defeats (losers) in daily male confrontations. |
1997-03-13 |
2023-08-12 |
mouse |
| L P Del Mar, R S Scrogg. Lactoseries carbohydrate antigen, Gal beta 1-4GlcNAc-R, is expressed by a subpopulation of capsaicin-sensitive rat sensory neurons. Journal of neurophysiology. vol 76. issue 4. 1997-03-11. PMID:8899594. |
a5+ and a5- cells differed regarding the inhibition of high-threshold ca2+ currents by maximal concentrations of 5ht1a agonists (10 microm 5ht or 1 microm 8-oh-dpat). |
1997-03-11 |
2023-08-12 |
mouse |
| M R Pranzatelli, M M Durkin, M Farme. Plastic responses of neonatal 5-hydroxytryptamine1B receptors to 5,7-dihydroxytryptamine lesions mapped by quantitative autoradiography. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 14. issue 5. 1997-03-11. PMID:8930693. |
we previously found different effects on behavior, serotonin (5-ht) concentrations, 5-ht uptake sites, and 5-ht1a binding sites of neonatal 5,7-dihydroxytryptamine (5,7-dht) lesions depending on the route of 5,7-dht injection. |
1997-03-11 |
2023-08-12 |
rat |
| M B Assié, W Koe. Possible in vivo 5-HT reuptake blocking properties of 8-OH-DPAT assessed by measuring hippocampal extracellular 5-HT using microdialysis in rats. British journal of pharmacology. vol 119. issue 5. 1997-03-10. PMID:8922730. |
to study the functional consequences of this property, the effects of 8-oh-dpat were compared with those of the 5-ht reuptake inhibitors, paroxetine and clomipramine, and of the 5-ht1a receptor agonist flesinoxan, in vitro on 5-ht reuptake, and in vivo on the extracellular concentration of 5-ht by use of microdialysis, in rat hippocampus. |
1997-03-10 |
2023-08-12 |
rat |
| M B Assié, W Koe. Possible in vivo 5-HT reuptake blocking properties of 8-OH-DPAT assessed by measuring hippocampal extracellular 5-HT using microdialysis in rats. British journal of pharmacology. vol 119. issue 5. 1997-03-10. PMID:8922730. |
these findings suggest that the increase in extracellular 5-ht produced by local administration of 8-oh-dpat does not involve its 5-ht1a receptor agonist properties, but may result, at least in part, from its 5-ht reuptake blocking properties. |
1997-03-10 |
2023-08-12 |
rat |
| A L Kirchgessner, M T Liu, J R Raymond, M D Gersho. Identification of cells that express 5-hydroxytryptamine1A receptors in the nervous systems of the bowel and pancreas. The Journal of comparative neurology. vol 364. issue 3. 1997-03-07. PMID:8820876. |
in addition to neurons, a subset of 5-ht-containing enterochromaffin cells expressed 5-ht1a immunoreactivity, which was co-localized with 5-ht in secretory granules. |
1997-03-07 |
2023-08-12 |
Not clear |