| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lara Costa, Alessandra Tempio, Enza Lacivita, Marcello Leopoldo, Lucia Cirann. Serotonin 5-HT7 receptors require cyclin-dependent kinase 5 to rescue hippocampal synaptic plasticity in a mouse model of Fragile X Syndrome. The European journal of neuroscience. 2021-08-18. PMID:33949019. |
we have previously demonstrated that activation of serotonin 5-ht7 receptors reverses mglur-ltd in the hippocampus of wild-type and fmr1 ko mice, thus correcting a synaptic dysfunction typically observed in this disease model. |
2021-08-18 |
2023-08-13 |
mouse |
| Irfan Cinar, Busra Sirin, Zekai Halici, Saziye Sezin Palabiyik-Yucelik, Erol Akpinar, Elif Cadirc. 5-HT7 receptors as a new target for prostate cancer physiopathology and treatment: an experimental study on PC-3 cells and FFPE tissues. Naunyn-Schmiedeberg's archives of pharmacology. vol 394. issue 6. 2021-07-19. PMID:33528589. |
the most recently discovered of these receptors is 5-ht7 but also least characterized receptors of serotonin. |
2021-07-19 |
2023-08-13 |
human |
| Jieon Lee, Diana Avramets, Byungsun Jeon, Hyunah Cho. Modulation of Serotonin Receptors in Neurodevelopmental Disorders: Focus on 5-HT7 Receptor. Molecules (Basel, Switzerland). vol 26. issue 11. 2021-07-12. PMID:34199418. |
modulation of serotonin receptors in neurodevelopmental disorders: focus on 5-ht7 receptor. |
2021-07-12 |
2023-08-13 |
Not clear |
| Qian Qian Liu, Xiao Xiao Yao, Shuo Hui Gao, Rui Li, Bing Jin Li, Wei Yang, Ran Ji Cu. Role of 5-HT receptors in neuropathic pain: potential therapeutic implications. Pharmacological research. vol 159. 2021-07-05. PMID:32464329. |
therefore, we summarized the recent findings on multiple subtypes of 5-ht receptors in both central and peripheral nervous system in neuropathic pain, particularly, 5-ht1, 5-ht2, 5-ht3 and 5-ht7 receptors. |
2021-07-05 |
2023-08-13 |
Not clear |
| Miguel A Núñez-Ochoa, Gustavo A Chiprés-Tinajero, Laura Medina-Cej. Evaluation of the hippocampal immunoreactivity of the serotonin 5-HT1A, 5-HT2 and 5-HT7 receptors in a pilocarpine temporal lobe epilepsy rat model with fast ripples. Neuroreport. vol 32. issue 4. 2021-06-18. PMID:33470771. |
evaluation of the hippocampal immunoreactivity of the serotonin 5-ht1a, 5-ht2 and 5-ht7 receptors in a pilocarpine temporal lobe epilepsy rat model with fast ripples. |
2021-06-18 |
2023-08-13 |
rat |
| Miguel A Núñez-Ochoa, Gustavo A Chiprés-Tinajero, Laura Medina-Cej. Evaluation of the hippocampal immunoreactivity of the serotonin 5-HT1A, 5-HT2 and 5-HT7 receptors in a pilocarpine temporal lobe epilepsy rat model with fast ripples. Neuroreport. vol 32. issue 4. 2021-06-18. PMID:33470771. |
therefore, to gather more details about the state of the serotoninergic system in the hippocampus under an epileptogenic process, we studied the immunoreactivity of three 5-ht receptors (5-ht1a, 5-ht2 and 5-ht7) as well as the extracellular levels of 5-ht in the hippocampal tissue of epileptic rats with fr. |
2021-06-18 |
2023-08-13 |
rat |
| Dasiel O Borroto-Escuela, Xiang Li, Alexander O Tarakanov, David Savelli, Manuel Narváez, Kirill Shumilov, Yuniesky Andrade-Talavera, Antonio Jimenez-Beristain, Bartosz Pomierny, Zaida Díaz-Cabiale, Riccardo Cuppini, Patrizia Ambrogini, Maria Lindskog, Kjell Fux. Existence of Brain 5-HT1A-5-HT2A Isoreceptor Complexes with Antagonistic Allosteric Receptor-Receptor Interactions Regulating 5-HT1A Receptor Recognition. ACS omega. vol 2. issue 8. 2020-10-01. PMID:28920103. |
there are many 5-ht subtypes involved; some need to be blocked (e.g., 5-ht2a, 5-ht3, and 5-ht7), whereas others need to be activated (e.g., postjunctional 5-ht1a and 5-ht4). |
2020-10-01 |
2023-08-13 |
Not clear |
| Yang-Yang Pang, Ya-Meng Song, Long Zhang, Xiao-Zhe Song, Cong Zhang, Jia-Huan Lv, Long He, Yong-Xu Cheng, Xiao-Zhen Yan. 5-HT2B, 5-HT7, and DA2 Receptors Mediate the Effects of 5-HT and DA on Agonistic Behavior of the Chinese Mitten Crab ( ACS chemical neuroscience. vol 10. issue 11. 2020-09-25. PMID:31642670. |
5-ht2b, 5-ht7, and da2 receptors mediate the effects of 5-ht and da on agonistic behavior of the chinese mitten crab ( the chinese mitten crab ( |
2020-09-25 |
2023-08-13 |
Not clear |
| Li-Jung Kang, Khoa V A Nguyen, Sanung Eom, Yeo-Jin Choi, Cam Ngoc Nguyen, Jaeeun Lee, Chaelin Kim, Shinhui Lee, Seong-Gene Lee, Jun-Ho Le. Stimulating DDX3 expression by serotonin 5-HT receptor 7 through phosphorylation of p53 via the AC-PKA-ERK signaling pathway. Journal of cellular biochemistry. vol 120. issue 10. 2020-09-14. PMID:31172579. |
stimulating ddx3 expression by serotonin 5-ht receptor 7 through phosphorylation of p53 via the ac-pka-erk signaling pathway. |
2020-09-14 |
2023-08-13 |
Not clear |
| Julie Le Mestre, Céline Duparc, Yves Reznik, Fidéline Bonnet-Serrano, Philippe Touraine, Olivier Chabre, Jacques Young, Mari Suzuki, Mathilde Sibony, Françoise Gobet, Constantine A Stratakis, Gérald Raverot, Jérôme Bertherat, Hervé Lefebvre, Estelle Louise. Illicit Upregulation of Serotonin Signaling Pathway in Adrenals of Patients With High Plasma or Intra-Adrenal ACTH Levels. The Journal of clinical endocrinology and metabolism. vol 104. issue 11. 2020-06-01. PMID:31074783. |
in primary pigmented nodular adrenocortical disease cells, activation of the camp/protein kinase a (pka) pathway by prkar1a mutations triggers upregulation of the 5-ht synthesizing enzyme tryptophan hydroxylase (tph) and the 5-ht4, 5-ht6, and 5-ht7 receptors. |
2020-06-01 |
2023-08-13 |
human |
| Tugba Nurcan Yuksel, Muhammed Yayla, Zekai Halici, Elif Cadirci, Beyzagul Polat, Duygu Kos. Protective effect of 5-HT7 receptor activation against glutamate-induced neurotoxicity in human neuroblastoma SH-SY5Y cells via antioxidative and antiapoptotic pathways. Neurotoxicology and teratology. vol 72. 2020-05-20. PMID:30685503. |
serotonin exerts anti-inflammatory, antioxidant and antiapoptotic effects through 5-ht7 receptors. |
2020-05-20 |
2023-08-13 |
human |
| Floriana Volpicelli, L Speranza, S Pulcrano, R De Gregorio, M Crispino, C De Sanctis, M Leopoldo, E Lacivita, U di Porzio, G C Bellenchi, C Perrone-Capan. The microRNA-29a Modulates Serotonin 5-HT7 Receptor Expression and Its Effects on Hippocampal Neuronal Morphology. Molecular neurobiology. vol 56. issue 12. 2020-04-02. PMID:31292861. |
the microrna-29a modulates serotonin 5-ht7 receptor expression and its effects on hippocampal neuronal morphology. |
2020-04-02 |
2023-08-13 |
mouse |
| Neeshu Saroj, Shiv Shanker, Manuel A Fernández-Parilla, Pedro López-Sánchez, José A Terró. Effect of chronic corticosterone treatment on expression and distribution of serotonin 5-HT7 receptors in rat adrenal glands. Canadian journal of physiology and pharmacology. vol 97. issue 10. 2020-03-05. PMID:31132324. |
effect of chronic corticosterone treatment on expression and distribution of serotonin 5-ht7 receptors in rat adrenal glands. |
2020-03-05 |
2023-08-13 |
rat |
| Neeshu Saroj, Shiv Shanker, Manuel A Fernández-Parilla, Pedro López-Sánchez, José A Terró. Effect of chronic corticosterone treatment on expression and distribution of serotonin 5-HT7 receptors in rat adrenal glands. Canadian journal of physiology and pharmacology. vol 97. issue 10. 2020-03-05. PMID:31132324. |
the effect of 14-day chronic cort and vehicle (veh) administration on 5-ht7 receptor expression in adrenal glands, adrenal 5-ht content, and adrenocorticotropic hormone and cort secretion was analysed. |
2020-03-05 |
2023-08-13 |
rat |
| Neeshu Saroj, Shiv Shanker, Manuel A Fernández-Parilla, Pedro López-Sánchez, José A Terró. Effect of chronic corticosterone treatment on expression and distribution of serotonin 5-HT7 receptors in rat adrenal glands. Canadian journal of physiology and pharmacology. vol 97. issue 10. 2020-03-05. PMID:31132324. |
5-ht7 receptor-like immunoreactivity (5-ht7r-li), 5-ht7 receptor protein, and mrna levels were determined by immunohistochemistry, western blot, and reverse transcription polymerase chain reaction assays, respectively; 5-ht levels and hormones were quantified using hplc and elisa kits, respectively. |
2020-03-05 |
2023-08-13 |
rat |
| Neeshu Saroj, Shiv Shanker, Manuel A Fernández-Parilla, Pedro López-Sánchez, José A Terró. Effect of chronic corticosterone treatment on expression and distribution of serotonin 5-HT7 receptors in rat adrenal glands. Canadian journal of physiology and pharmacology. vol 97. issue 10. 2020-03-05. PMID:31132324. |
chronic cort strongly increased 5-ht7r-li in the outer adrenal cortex, as well as 5-ht7 receptor protein and mrna in whole adrenal glands; adrenal 5-ht content also increased in these animals. |
2020-03-05 |
2023-08-13 |
rat |
| Neeshu Saroj, Shiv Shanker, Manuel A Fernández-Parilla, Pedro López-Sánchez, José A Terró. Effect of chronic corticosterone treatment on expression and distribution of serotonin 5-HT7 receptors in rat adrenal glands. Canadian journal of physiology and pharmacology. vol 97. issue 10. 2020-03-05. PMID:31132324. |
the results support the notion that chronic stress-induced increase of adrenocortical 5-ht7 receptors and adrenal 5-ht content is a glucocorticoid-dependent phenomenon; the development of magnified stress-induced 5-ht7 receptor-mediated cort responses in chronically stressed animals nevertheless likely involves additional mechanisms. |
2020-03-05 |
2023-08-13 |
rat |
| Yu Ohmura, Takayuki Yoshida, Kohtarou Konno, Masabumi Minami, Masahiko Watanabe, Mitsuhiro Yoshiok. Serotonin 5-HT7 Receptor in the Ventral Hippocampus Modulates the Retrieval of Fear Memory and Stress-Induced Defecation. The international journal of neuropsychopharmacology. vol 19. issue 6. 2019-11-20. PMID:26647382. |
serotonin 5-ht7 receptor in the ventral hippocampus modulates the retrieval of fear memory and stress-induced defecation. |
2019-11-20 |
2023-08-13 |
Not clear |
| E M Kondaurova, D V Bazovkina, V S Naumenk. [5-HT1A/5-HT7 receptor interplay: Chronic activation of 5-HT7 receptors decreases the functional activity of 5-HT1A receptor and its сontent in the mouse brain]. Molekuliarnaia biologiia. vol 51. issue 1. 2019-04-30. PMID:28251979. |
serotonin receptors 5-ht1a and 5-ht7 are involved in the development of various psychopathologies. |
2019-04-30 |
2023-08-13 |
mouse |
| Yong Zhang, Yupu Liang, Matthew Randesi, Vadim Yuferov, Connie Zhao, Mary Jeanne Kree. Chronic Oxycodone Self-administration Altered Reward-related Genes in the Ventral and Dorsal Striatum of C57BL/6J Mice: An RNA-seq Analysis. Neuroscience. vol 393. 2019-03-07. PMID:30059705. |
the following 5 genes in the ventral striatum showed experiment-wise significant changes: proopiomelanocortin (pomc) and serotonin 5-ht-2a receptor (htr2a) were upregulated; serotonin receptor 7 (htr7), galanin receptor1 (galr1) and glycine receptor 1 (glra1) were downregulated. |
2019-03-07 |
2023-08-13 |
mouse |