| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Danielle A Diniz, Júlia Alvarenga Petrocchi, Larissa Caldeira Navarro, Tâmara Cristina Souza, Marina G M Castor, Andrea C Perez, Igor D G Duarte, Thiago R L Romer. Serotonin induces peripheral mechanical antihyperalgesic effects in mice. European journal of pharmacology. vol 767. 2016-10-05. PMID:26460149. |
in contrast, selective antagonists for 5-ht1d and 5-ht7 receptors were unable to reverse the antihyperalgesic effect induced by serotonin. |
2016-10-05 |
2023-08-13 |
mouse |
| Pellegrino Lippiello, Eriola Hoxha, Luisa Speranza, Floriana Volpicelli, Angela Ferraro, Marcello Leopoldo, Enza Lacivita, Carla Perrone-Capano, Filippo Tempia, Maria Concetta Miniac. The 5-HT7 receptor triggers cerebellar long-term synaptic depression via PKC-MAPK. Neuropharmacology. vol 101. 2016-10-05. PMID:26482421. |
the 5-ht7 receptor (5-ht7r) mediates important physiological effects of serotonin, such as memory and emotion, and is emerging as a therapeutic target for the treatment of cognitive disorders and depression. |
2016-10-05 |
2023-08-13 |
mouse |
| Nikolas Stroth, Per Svenningsso. S100B interacts with the serotonin 5-HT7 receptor to regulate a depressive-like behavior. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 12. 2016-10-05. PMID:26499172. |
s100b interacts with the serotonin 5-ht7 receptor to regulate a depressive-like behavior. |
2016-10-05 |
2023-08-13 |
mouse |
| Nikolas Stroth, Per Svenningsso. S100B interacts with the serotonin 5-HT7 receptor to regulate a depressive-like behavior. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 12. 2016-10-05. PMID:26499172. |
the serotonin 5-ht7 receptor (5-ht7) is an emerging target for psychiatric pharmacotherapy. |
2016-10-05 |
2023-08-13 |
mouse |
| Lakshmi Rajagopal, Bill W Massey, Eric Michael, Herbert Y Meltze. Serotonin (5-HT)1A receptor agonism and 5-HT7 receptor antagonism ameliorate the subchronic phencyclidine-induced deficit in executive functioning in mice. Psychopharmacology. vol 233. issue 4. 2016-09-20. PMID:26558619. |
serotonin (5-ht)1a receptor agonism and 5-ht7 receptor antagonism ameliorate the subchronic phencyclidine-induced deficit in executive functioning in mice. |
2016-09-20 |
2023-08-13 |
mouse |
| Małgorzata Hołuj, Piotr Popik, Agnieszka Nikiforu. Improvement of ketamine-induced social withdrawal in rats: the role of 5-HT7 receptors. Behavioural pharmacology. vol 26. issue 8 Spec No. 2016-08-22. PMID:25769091. |
we have recently shown that amisulpride, an antipsychotic with a high affinity for serotonin 5-ht7 receptors, reversed ketamine-induced si deficits in rats. |
2016-08-22 |
2023-08-13 |
rat |
| Steven C Leiser, Deborah Iglesias-Bregna, Ligia Westrich, Alan L Pehrson, Connie Sanche. Differentiated effects of the multimodal antidepressant vortioxetine on sleep architecture: Part 2, pharmacological interactions in rodents suggest a role of serotonin-3 receptor antagonism. Journal of psychopharmacology (Oxford, England). vol 29. issue 10. 2016-06-23. PMID:26174134. |
vortioxetine, a multimodal antidepressant acting through serotonin (5-ht) transporter (sert) inhibition, 5-ht3, 5-ht7 and 5-ht1d receptor antagonism, 5-ht1b receptor partial agonism, and 5-ht1a receptor agonism, had fewer incidences of sleep-related adverse events reported in depressed patients. |
2016-06-23 |
2023-08-13 |
human |
| Agnieszka Gunia-Krzyzak, Karolina Pytka, Karolina Słoczyńska, Anna M Waszkielewicz, Grzegorz Satała, Andrzej J Bojarski, Jacek Sapa, Barbara Filipek, Marek Cegła, Elzbieta Pekala, Henryk Maron. PRELIMINARY EVALUATION OF CENTRAL NERVOUS SYSTEM ACTIVITY OF (E)-N-2-METHYL-3-PHENYLPROP-2-ENYL ((E)-N- α-METHYLCINNAMYL) DERIVATIVES OF SELECTED AMINOALKANOLS. Acta poloniae pharmaceutica. vol 73. issue 2. 2016-06-20. PMID:27180427. |
to identify possible mechanism of action, we evaluated serotonin receptors (5-ht1a, 5-ht6 and 5-ht7) binding affinities of the compounds but none of them proved to bind to any of tested receptors. |
2016-06-20 |
2023-08-13 |
mouse |
| D P Fields, S R Springborn, G S Mitchel. Spinal 5-HT7 receptors induce phrenic motor facilitation via EPAC-mTORC1 signaling. Journal of neurophysiology. vol 114. issue 3. 2016-06-17. PMID:26269554. |
spinal serotonin type 7 (5-ht7) receptors elicit complex effects on motor activity. |
2016-06-17 |
2023-08-13 |
rat |
| Paola Nativio, Francesca Zoratto, Emilia Romano, Enza Lacivita, Marcello Leopoldo, Esterina Pascale, Francesca Passarelli, Giovanni Laviola, Walter Adrian. Stimulation of 5-HT7 receptor during adolescence determines its persistent upregulation in adult rat forebrain areas. Synapse (New York, N.Y.). vol 69. issue 11. 2016-06-17. PMID:26364910. |
brain serotonin 7 (5-ht7) receptors play an important functional role in learning and memory, in regulation of mood and motivation, and for circadian rhythms. |
2016-06-17 |
2023-08-13 |
rat |
| Agnieszka Nikiforu. Targeting the Serotonin 5-HT7 Receptor in the Search for Treatments for CNS Disorders: Rationale and Progress to Date. CNS drugs. vol 29. issue 4. 2016-06-13. PMID:25721336. |
targeting the serotonin 5-ht7 receptor in the search for treatments for cns disorders: rationale and progress to date. |
2016-06-13 |
2023-08-13 |
mouse |
| Agnieszka Nikiforu. Targeting the Serotonin 5-HT7 Receptor in the Search for Treatments for CNS Disorders: Rationale and Progress to Date. CNS drugs. vol 29. issue 4. 2016-06-13. PMID:25721336. |
the 5-ht7 (5-hydroxytryptamine 7, serotonin 7) receptor is one of the most recently identified members of the serotonin receptor family. |
2016-06-13 |
2023-08-13 |
mouse |
| Abbas Norouzi-Javidan, Javad Javanbakht, Fardin Barati, Nahid Fakhraei, Fatemeh Mohammadi, Ahmad Reza Dehpou. Serotonin 5-HT7 receptor agonist, LP-211, exacerbates Na(+), K(+)-ATPase/Mg(2+)-ATPase imbalances in spinal cord-injured male rats. Diagnostic pathology. vol 10. 2016-05-27. PMID:26369408. |
serotonin 5-ht7 receptor agonist, lp-211, exacerbates na(+), k(+)-atpase/mg(2+)-atpase imbalances in spinal cord-injured male rats. |
2016-05-27 |
2023-08-13 |
rat |
| Abbas Norouzi-Javidan, Javad Javanbakht, Fardin Barati, Nahid Fakhraei, Fatemeh Mohammadi, Ahmad Reza Dehpou. Serotonin 5-HT7 receptor agonist, LP-211, exacerbates Na(+), K(+)-ATPase/Mg(2+)-ATPase imbalances in spinal cord-injured male rats. Diagnostic pathology. vol 10. 2016-05-27. PMID:26369408. |
the observed controversy that n-(4-cyanophenylmethyl)-4-(2-diphenyl)-1-piperazinehexanamide (lp-211), a selective serotonin (5-ht7) receptor agonist, may either modify or exacerbate imbalances in serum electrolyte concentrations and renal tissue of spinal cord trauma cases has not been reported yet. |
2016-05-27 |
2023-08-13 |
rat |
| Tetsuya Imamura, Osamu Ishizuka, Teruyuki Ogawa, Tomonori Minagawa, Masakuni Ishikawa, Shiro Hiragata, Hitoshi Yokoyama, Masaki Nakazawa, Yoshiki Kurizaki, Osamu Nishizaw. Expression of 5-Hydroxytryptamine Receptors in Human Urinary Bladders with Benign Prostatic Hyperplasia. Advances in therapy. vol 32 Suppl 1. 2016-05-25. PMID:26391373. |
this study investigated the mrna expression pattern and distribution of 5-hydroxytryptamine (5-ht) receptors 5-ht2a, 5-ht2b, 5-ht3a, 5-ht4, and 5-ht7 within the urothelium and detrusor of normal bladder tissue and in the urothelium of bladders from patients with benign prostatic hyperplasia (bph). |
2016-05-25 |
2023-08-13 |
human |
| Ozgur Yesilyurt, Melik Seyrek, Serdar Tasdemir, Serdar Kahraman, Mehmet Salih Deveci, Emre Karakus, Zekai Halici, Ahmet Dogru. The critical role of spinal 5-HT7 receptors in opioid and non-opioid type stress-induced analgesia. European journal of pharmacology. vol 762. 2016-05-24. PMID:25917322. |
we previously reported that the spinal serotonin 7 receptor (5-ht7) blockers inhibit both morphine and cannabinoid-induced analgesia, thus we hypothesized that descending serotonergic pathways-spinal 5-ht7 receptor loop might contribute to stress-induced analgesia. |
2016-05-24 |
2023-08-13 |
mouse |
| Ozgur Yesilyurt, Melik Seyrek, Serdar Tasdemir, Serdar Kahraman, Mehmet Salih Deveci, Emre Karakus, Zekai Halici, Ahmet Dogru. The critical role of spinal 5-HT7 receptors in opioid and non-opioid type stress-induced analgesia. European journal of pharmacology. vol 762. 2016-05-24. PMID:25917322. |
the expression of 5-ht7 receptors mrna in the dorsal lumbar region of spinal cord were analyzed by rt-pcr following spinal serotonin depletion or dorsolateral funiculus lesion. |
2016-05-24 |
2023-08-13 |
mouse |
| Ornella Manfra, Kathleen Van Craenenbroeck, Kamila Skieterska, Thomas Frimurer, Thue W Schwartz, Finn Olav Levy, Kjetil Wessel Andresse. Downregulation of 5-HT7 Serotonin Receptors by the Atypical Antipsychotics Clozapine and Olanzapine. Role of Motifs in the C-Terminal Domain and Interaction with GASP-1. ACS chemical neuroscience. vol 6. issue 7. 2016-04-19. PMID:25706089. |
downregulation of 5-ht7 serotonin receptors by the atypical antipsychotics clozapine and olanzapine. |
2016-04-19 |
2023-08-13 |
human |
| Clinton E Canal, Daniel E Felsing, Yue Liu, Wanying Zhu, JodiAnne T Wood, Charles K Perry, Rajender Vemula, Raymond G Boot. An Orally Active Phenylaminotetralin-Chemotype Serotonin 5-HT7 and 5-HT1A Receptor Partial Agonist that Corrects Motor Stereotypy in Mouse Models. ACS chemical neuroscience. vol 6. issue 7. 2016-04-19. PMID:26011730. |
an orally active phenylaminotetralin-chemotype serotonin 5-ht7 and 5-ht1a receptor partial agonist that corrects motor stereotypy in mouse models. |
2016-04-19 |
2023-08-13 |
mouse |
| N K Popova, E G Ponimaskin, V S Naumenk. [CROSS-TALK BETWEEN 5-HT1A AND 5-HT7 RECEPTORS: ROLE IN THE AUTOREGULATION OF THE BRAIN SEROTONIN SYSTEM AND IN MECHANISM OF ANTIDEPRESSANTS ACTION]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 101. issue 11. 2016-04-08. PMID:26995955. |
the results described in the present review indicate that: i) dimerization and formation of mobile receptor complexes is a common feature for the members of g-protein coupled receptor superfamily; ii) 5-ht7 receptor appears to be a modulator for 5-ht1a receptor - the key autoregulator of the brain serotonin system; iii) 5-ht1a/5-ht7 receptor complexes formation is one of the mechanisms for inactivation and desensitization of the 5-htia receptors in the brain; iv) differences in the 5-ht7 receptor and 5-htia/5-ht7 heterodimers density define different sensitivity of pre- and postsynaptic 5-htla receptors to chronic treatment with selective serotonin reuptake inhibitors. |
2016-04-08 |
2023-08-13 |
Not clear |