| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ameer Elena Rasool, Teri Furlong, Asheeta A Prasa. Microglia activity in the human basal ganglia is altered in alcohol use disorder and reversed with remission from alcohol. Addiction biology. vol 29. issue 2. 2024-02-21. PMID:38380734. |
immunohistochemistry was performed to analyze cell count, staining intensity, and morphology of microglia and astrocytes, using markers iba-1 and gfap. |
2024-02-21 |
2024-02-23 |
human |
| Guido S Alvarez Quintero, Analia Lima, Paulina Roig, Maria Meyer, E Ron de Kloet, Alejandro F De Nicola, Laura I Gara. effects of the mineralocorticoid receptor antagonist eplerenone in experimental autoimmune encephalomyelitis. The Journal of steroid biochemistry and molecular biology. 2024-01-14. PMID:38219844. |
the mr blocker (a) significantly decreased the inflammatory parameters tlr4, myd88, il-1β, and inos mrnas; (b) attenuated hmgb1, nlrp3, tgf-β mrnas, microglia, and aquaporin4 immunoreaction without modifying gfap. |
2024-01-14 |
2024-01-17 |
mouse |
| Kentaro Suda, Jaime Pignatelli, Laura Genis, Ana M Fernandez, Estrella Fernandez de Sevilla, Ines Fernandez de la Cruz, Andrea Pozo-Rodrigalvarez, Maria L de Ceballos, Sonia Díaz-Pacheco, Raquel Herrero-Labrador, Ignacio Torres Alema. A role for astrocytic insulin-like growth factor I receptors in the response to ischemic insult. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2023-11-28. PMID:38017004. |
further, greater damage was also accompanied by altered glial reactivity as reflected by changes in the morphology of gfap astrocytes, and relative abundance of ionized calcium binding adaptor molecule 1 (iba 1) microglia. |
2023-11-28 |
2023-12-07 |
mouse |
| Maurício Dos Santos Pereira, Bruna Maitan Santos, Rocio Gimenez, Francisco Silveira Guimarães, Rita Raisman-Vozari, Elaine Del Bel, Patrick Pierre Miche. The two synthetic cannabinoid compounds 4'-F-CBD and HU-910 efficiently restrain inflammatory responses of brain microglia and astrocytes. Glia. 2023-11-28. PMID:38013496. |
upon lps challenge, 4'-f-cbd and hu-910 also prevented the activation of phenotypic activation markers specific to microglia and astrocytes, that is, iba-1 and gfap, respectively. |
2023-11-28 |
2023-11-29 |
mouse |
| Fernanda Huf, Jessié Martins Gutierres, Gabrielle N da Silva, Adriana M Zago, Luiz Felipe C Koenig, Marilda C Fernande. Neuroprotection elicited by taurine in sporadic Alzheimer-like disease: benefits on memory and control of neuroinflammation in the hippocampus of rats. Molecular and cellular biochemistry. 2023-10-24. PMID:37874493. |
insulin receptor (ir) was evaluated by immunoperoxidase while mature neurons (neun), astrocytes (gfap, s100b, sox9), and microglia (iba-1) were evaluated by immunofluorescence. |
2023-10-24 |
2023-11-08 |
rat |
| D R De Paula, M S França, L K R Leão, A A Maciel, T A A Moura, S A S de Moraes, C P Bahia, R S Borges, E J O Batista, A C F Passos, K R H M Oliveira, A M Herculan. Total rupture of Achilles tendon induces inflammatory response and glial activation on the spinal cord of mice. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 56. 2023-10-21. PMID:37851789. |
this phenomenon was accompanied by overexpression of cyclooxygenase-2 (cox-2) and inducible nitric oxide synthase-2 (nos-2) as well as hyperactivation of astrocytes and microglia in nociceptive areas of l5 spinal cord as evidenced by intense gfap and iba-1 immunostaining, respectively. |
2023-10-21 |
2023-11-08 |
mouse |
| Valentin Garcia, Marine Blaquiere, Alicia Janvier, Noemie Cresto, Carla Lana, Athenais Genin, Helene Hirbec, Etienne Audinat, Adele Faucherre, Emmanuel L Barbier, Sophie Hamelin, Philippe Kahane, Chris Jopling, Nicola March. PIEZO1 expression at the glio-vascular unit adjusts to neuroinflammation in seizure conditions. Neurobiology of disease. 2023-09-17. PMID:37717661. |
post-se and during epileptogenesis, ameboid iba1 microglia, hypertrophic gfap astrocytes, and damaged ng2dsred pericytes exhibited time-dependent patterns of increased piezo1 expression. |
2023-09-17 |
2023-10-07 |
mouse |
| Iain J Hartnell, Declan Woodhouse, William Jasper, Luke Mason, Pavan Marwaha, Manon Graffeuil, Laurie C Lau, Jeanette L Norman, David S Chatelet, Luc Buee, James A R Nicoll, David Blum, Guillaume Dorothee, Delphine Boch. Glial reactivity and T cell infiltration in frontotemporal lobar degeneration with tau pathology. Brain : a journal of neurology. 2023-09-13. PMID:37703311. |
the immunophenotypes of microglia and astrocytes were assessed with phenotypic markers (iba1, cd68, hla-dr, cd64, cd32a, cd16 for microglia and gfap, eaat2, glutamine synthetase and aldh1l1 for astrocytes). |
2023-09-13 |
2023-10-07 |
mouse |
| Haley F Spencer, Martin Boese, Rina Y Berman, Kennett D Radford, Kwang H Cho. Effects of a Subanesthetic Ketamine Infusion on Inflammatory and Behavioral Outcomes after Closed Head Injury in Rats. Bioengineering (Basel, Switzerland). vol 10. issue 8. 2023-08-26. PMID:37627826. |
brain tissue samples were collected at pid 4 and processed for gfap (astrocytes), iba-1 (microglia), and silver staining (axonal injury). |
2023-08-26 |
2023-09-07 |
rat |
| Mohammed Z Rizwan, Romy Kerbus, Kaj Kamstra, Pramuk Keerthisinghe, Alexander Tup. Dietary wheat gluten induces astro- and microgliosis in the hypothalamus of male mice. Journal of neuroendocrinology. 2023-08-03. PMID:37534400. |
gluten regardless of whether it was added to lfd or hfd led to a profound increase in the number of microglia and astrocytes in the arcuate nucleus of the hypothalamus, as detected by immunohistochemistry for ionised calcium binding adaptor molecule 1 (iba-1) and glial fibrillary acidic protein (gfap), respectively. |
2023-08-03 |
2023-08-14 |
mouse |
| Zhi-Ling Zhang, Zhi-Tong Wang, Jing Shi, Xiao-Ping Pu, Suo-Di Zha. Tetrandrine attenuates SNI-induced mechanical allodynia by inhibiting spinal CKLF1. Neuropharmacology. 2023-07-30. PMID:37517461. |
western blotting and immunofluorescence staining showed that tet significantly inhibited spinal protein expression levels of cklf1, p-nf-κb/nf-κb, p-ikk/ikk, pro-inflammatory cytokines il-1β and tnf-α, and increased protein expression levels of the anti-inflammatory cytokine il-10, while inhibiting the expression levels of microglia and astrocyte markers iba-1 and gfap of sni mice. |
2023-07-30 |
2023-08-14 |
mouse |
| Osama F Elabi, Elena Espa, Katrine Skovgård, Silvia Fanni, Maria Angela Cenc. Ropinirole Cotreatment Prevents Perivascular Glial Recruitment in a Rat Model of L-DOPA-Induced Dyskinesia. Cells. vol 12. issue 14. 2023-07-29. PMID:37508522. |
immunohistochemistry was used to examine the reactivity of microglia (ionized calcium-binding adapter molecule 1, iba-1) and astroglia (glial fibrillary acidic protein, gfap), as well as blood vessel density (rat endothelial cell antigen 1, reca-1) and albumin extravasation. |
2023-07-29 |
2023-08-14 |
rat |
| Georg Prokop, Benedikt Wiestler, Daniel Hieber, Fynn Withake, Karoline Mayer, Jens Gempt, Claire Delbridge, Friederike Schmidt-Graf, Nicole Pfarr, Bruno Märkl, Jürgen Schlegel, Friederike Liesche-Starnecke. Multiscale quantification of morphological heterogeneity with creation of a predictor of longer survival in glioblastoma. International journal of cancer. 2023-07-28. PMID:37501565. |
with this aim, 157 biopsies of 37 patients with therapy-naive idh-wildtype gbm were analyzed regarding the intratumor variance of protein expression of glial marker gfap, microglia marker iba1 and proliferation marker mib1. |
2023-07-28 |
2023-08-14 |
Not clear |
| Thomas Jacobus Geus, Glenn Franken, Bert Bert Jooste. Conventional, High Frequency and Differential Targeted Multiplexed Spinal Cord Stimulation in experimental Painful Diabetic Peripheral Neuropathy: pain behavior and role of the central inflammatory balance. Molecular pain. 2023-07-25. PMID:37488684. |
the inflammatory balance and glial response were analyzed in the dorsal spinal cord based on rna expression of pro- and anti-inflammatory cytokines (tnf-α, il-1ß, il-4, il-10), a microglia marker (itgam), an astrocyte marker (gfap), a t-cell marker (cd3d), microglia proliferation markers (irf8, adgre1) and p2x4, p13-mapk, bdnf signaling markers (p2x4, mapk14, bdnf). |
2023-07-25 |
2023-08-14 |
Not clear |
| Inez Koopman, Bart J van Dijk, Nicolaas P A Zuithoff, Jacqueline A Sluijs, Marije J van der Kamp, Zelonna A V Baldew, Catharina J M Frijns, Gabriel J E Rinkel, Elly M Hol, Mervyn D I Vergouwe. Glial cell response and microthrombosis in aneurysmal subarachnoid hemorrhage patients: An autopsy study. Journal of neuropathology and experimental neurology. 2023-07-21. PMID:37478478. |
in comparison with controls, we found increased numbers of microglia (mean ± sem 50 ± 8 vs 20 ± 5 per 0.0026 mm³, p < 0.01), an increased surface area (%) of microglia (mean ± sem 4.2 ± 0.6 vs 2.2 ± 0.4, p < 0.05), a higher intensity of the astrocytic intermediate filament protein glial fibrillary acidic protein (gfap) (mean ± sem 184 ± 28 vs 92 ± 23 arbitrary units, p < 0.05), and an increased gfap surface area (%) (mean ± sem 21.2 ± 2.6 vs 10.7 ± 2.1, p < 0.01) in asah tissue. |
2023-07-21 |
2023-08-14 |
Not clear |
| Maiko Inoue, Takashi Tanida, Tomohiro Kondo, Shigeo Takenaka, Takayuki Nakajim. Oxygen-glucose deprivation-induced glial cell reactivity in the rat primary neuron-glia co-culture. The Journal of veterinary medical science. 2023-07-05. PMID:37407448. |
in contrast, glial fibrillary acidic protein (gfap)-immunopositive astrocytes and ionized calcium-binding adapter protein-1 (iba-1)-immunopositive microglia, and 2',3'-cyclic nucleotide-3'-phosphodiesterase (cnpase)-immunopositive oligodendrocytes survived ogd. |
2023-07-05 |
2023-08-14 |
rat |
| Maiko Inoue, Takashi Tanida, Tomohiro Kondo, Shigeo Takenaka, Takayuki Nakajim. Oxygen-glucose deprivation-induced glial cell reactivity in the rat primary neuron-glia co-culture. The Journal of veterinary medical science. 2023-07-05. PMID:37407448. |
therefore, applying ogd to ngc cells could serve as a useful in vitro tool to elucidate the molecular mechanisms underlying brain ischemia-induced changes in gfap expression, astrocyte proliferation, and m1 microglia phenotype-related gene expression. |
2023-07-05 |
2023-08-14 |
rat |
| Gumaro Galindo-Paredes, Gonzalo Flores, Julio César Morales-Medin. Olfactory bulbectomy induces nociceptive alterations associated with gliosis in male rats. IBRO neuroscience reports. vol 14. 2023-06-30. PMID:37388490. |
quantitative morphological analysis, as well as assessment of the number of glial fibrillary acidic protein (gfap) and ionizing calcium-binding adaptor molecule 1 (iba1) positive astrocytes and microglia were carried out to characterize glial remodeling and density, respectively. |
2023-06-30 |
2023-08-14 |
rat |
| Abubakar Atiq, Hyeon Jin Lee, Amjad Khan, Min Hwa Kang, Inayat Ur Rehman, Riaz Ahmad, Muhammad Tahir, Jawad Ali, Kyonghwan Choe, Jun Sung Park, Myeong Ok Ki. Vitamin E Analog Trolox Attenuates MPTP-Induced Parkinson's Disease in Mice, Mitigating Oxidative Stress, Neuroinflammation, and Motor Impairment. International journal of molecular sciences. vol 24. issue 12. 2023-06-28. PMID:37373089. |
lastly, trolox treatment inhibited the activated astrocytes (gfap) and microglia (iba-1), also reducing phosphorylated nuclear factor-κb, (p-nf-κb) and tumor necrosis factor-alpha (tnf-α) in the pd mouse brain. |
2023-06-28 |
2023-08-14 |
mouse |
| Nundehui Díaz-Lezama, Jacqueline Kajtna, Jiou Wu, Monika Ayten, Susanne F Koc. Microglial and macroglial dynamics in a model of retinitis pigmentosa. Vision research. vol 210. 2023-06-09. PMID:37295269. |
we demonstrated an increased number of activated microglia, retraction of microglial processes, reactive gliosis of müller cells, astrocyte remodelling and an upregulation of glial fibrillary acidic protein (gfap) in response to photoreceptor degeneration. |
2023-06-09 |
2023-08-14 |
mouse |