| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiaoli Wang, Yun Xu, Fang Wang, Lihua Tang, Zhilong Liu, Honglian Li, Shenghong Li. Aging-related changes of microglia and astrocytes in hypothalamus after intraperitoneal injection of hypertonic saline in rats. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 26. issue 2. 2008-05-12. PMID:16850755. |
lectin histochemical techniques using ricinus communis agglutinin-1 (rca-1) and immunocytochemical method employing antibody against glial fibrillary acidic protein (gfap) were used to demonstrate microglia and astrocytes in the hypothalamus of the rats, and the positively-stained cells were analyzed by computer-assisted image analysis system. |
2008-05-12 |
2023-08-12 |
rat |
| Tetsuhiro Niidome, Satoru Matsuda, Hideki Nonaka, Akinori Akaike, Takeshi Kihara, Hachiro Sugimot. A molecular pathway involved in the generation of microtubule-associated protein 2-positive cells from microglia. Biochemical and biophysical research communications. vol 370. issue 1. 2008-05-12. PMID:18361915. |
we have recently demonstrated that microglia as multipotential stem cells give rise to microtubule-associated protein 2 (map2)-positive and glial fibrillary acidic protein (gfap)-positive cells and that microglia-derived map2-positive cells possess properties of functional neurons. |
2008-05-12 |
2023-08-12 |
Not clear |
| Stefania Echeverry, Xiang Qun Shi, Ji Zhan. Characterization of cell proliferation in rat spinal cord following peripheral nerve injury and the relationship with neuropathic pain. Pain. vol 135. issue 1-2. 2008-03-25. PMID:17560721. |
the majority of the proliferating cells were iba-1(+) microglia, together with some ng2(+) oligodendrocyte progenitors, and gfap(+) astrocytes. |
2008-03-25 |
2023-08-12 |
rat |
| W T J Hendriks, R Eggers, J Verhaagen, G J Boe. Gene transfer to the spinal cord neural scar with lentiviral vectors: predominant transgene expression in astrocytes but not in meningeal cells. Journal of neuroscience research. vol 85. issue 14. 2008-02-14. PMID:17671987. |
the colocalization of gfp with specific cell markers (gfap, vimentin, raldh2, neun, ox-42, ed-1, and ng-2) indicated that the predominant cells transduced in the rim of the lesion were astrocytes, with neurons, microglia, oligodendrocyte precursors, and macrophages transduced to a lesser extent. |
2008-02-14 |
2023-08-12 |
rat |
| Sarah M Rothman, Beth A Winkelstei. Chemical and mechanical nerve root insults induce differential behavioral sensitivity and glial activation that are enhanced in combination. Brain research. vol 1181. 2008-01-29. PMID:17920051. |
mechanical allodynia was assessed, and glial reactivity in the c7 spinal cord tissue was assayed at days 1 and 7 by immunohistochemistry using gfap and ox-42 as markers of astrocytes and microglia, respectively. |
2008-01-29 |
2023-08-12 |
Not clear |
| M S Petrik, J M B Wilson, S C Grant, S J Blackband, R C Tabata, X Shan, C Krieger, C A Sha. Magnetic resonance microscopy and immunohistochemistry of the CNS of the mutant SOD murine model of ALS reveals widespread neural deficits. Neuromolecular medicine. vol 9. issue 3. 2007-12-27. PMID:17914180. |
increased apoptosis, gfap positive astrocytes, and/or activated microglia were observed in all those cns regions that showed volume loss except for the hippocampus. |
2007-12-27 |
2023-08-12 |
mouse |
| Darice Y Wong, Scott J Hollister, Paul H Krebsbach, Christopher Nosra. Poly(epsilon-caprolactone) and poly (L-lactic-co-glycolic acid) degradable polymer sponges attenuate astrocyte response and lesion growth in acute traumatic brain injury. Tissue engineering. vol 13. issue 10. 2007-11-26. PMID:17655492. |
morphology, defect size, activation of microglia (ox-42) and astrocytes (glial fibrillary acidic protein (gfap)), infiltration of activated macrophages (major histocompatibility complex (mhc)-ii), and ingrowth of neurons (beta-tubulin type iii (tuj-1)) and progenitor cells (nestin) were analyzed using hematoxylin and eosin staining and immunofluorescence. |
2007-11-26 |
2023-08-12 |
rat |
| I Klejbor, E K Stachowiak, D J Bharali, I Roy, I Spodnik, J Morys, E J Bergey, P N Prasad, M K Stachowia. ORMOSIL nanoparticles as a non-viral gene delivery vector for modeling polyglutamine induced brain pathology. Journal of neuroscience methods. vol 165. issue 2. 2007-11-20. PMID:17655935. |
in both routes of transfection, q127 induced the appearance of reactive gfap (+) astrocytes and activated ed1 antigen expressing microglia. |
2007-11-20 |
2023-08-12 |
mouse |
| Michael D Lovelace, David M Cahil. A rapid cell counting method utilising acridine orange as a novel discriminating marker for both cultured astrocytes and microglia. Journal of neuroscience methods. vol 165. issue 2. 2007-11-20. PMID:17662460. |
previously, we reported the use of l-leucine methyl ester (l-lme) to prepare purified cultures of type 1 astrocytes with minimal microglia, and staining by gfap and cd antibodies, respectively. |
2007-11-20 |
2023-08-12 |
Not clear |
| Milan Makwana, Leonard L Jones, Dan Cuthill, Heike Heuer, Marion Bohatschek, Mariya Hristova, Sönke Friedrichsen, Ilona Ormsby, Dietmute Bueringer, Andrea Koppius, Karl Bauer, Thomas Doetschman, Gennadij Raivic. Endogenous transforming growth factor beta 1 suppresses inflammation and promotes survival in adult CNS. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 42. 2007-11-08. PMID:17942715. |
astrocytes increased in gfap and cd44 immunoreactivity; microglia showed proliferative activity, expression of phagocytosis-associated markers [alphaxbeta2, b7.2, and mhc1 (major histocompatibility complex type 1)], and reduced branching. |
2007-11-08 |
2023-08-12 |
mouse |
| A M M Silva, A R Silva, A M Pinheiro, S R V B Freitas, V D A Silva, C S Souza, J B Hughes, R S El-Bachá, M F D Costa, E S Velozo, M Tardy, S L Cost. Alkaloids from Prosopis juliflora leaves induce glial activation, cytotoxicity and stimulate NO production. Toxicon : official journal of the International Society on Toxinology. vol 49. issue 5. 2007-09-26. PMID:17241650. |
morphological changes and glial cells activation were investigated through rosenfeld's staining, by immunocytochemistry for the protein ox-42, specific of activated microglia, by immunocytochemistry and western immunoblot for gfap, the marker of reactive and mature astrocytes, and by the production of nitric oxide (no). |
2007-09-26 |
2023-08-12 |
rat |
| Sachiko Homma, Xiongjie Jin, Guanghu Wang, Naxin Tu, Jinna Min, Nathan Yanasak, Nahid F Mivech. Demyelination, astrogliosis, and accumulation of ubiquitinated proteins, hallmarks of CNS disease in hsf1-deficient mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 30. 2007-08-20. PMID:17652588. |
concomitantly, hsf1-/- aged cns exhibit increased activated microglia and apoptotic cells that are mainly positive for gfap, an astrocyte-specific marker. |
2007-08-20 |
2023-08-12 |
mouse |
| Adelina Holguin, Matthew G Frank, Joseph C Biedenkapp, Kristen Nelson, Dylan Lippert, Linda R Watkins, Jerry W Rudy, Steven F Maie. Characterization of the temporo-spatial effects of chronic bilateral intrahippocampal cannulae on interleukin-1beta. Journal of neuroscience methods. vol 161. issue 2. 2007-06-12. PMID:17241670. |
cannulation increased the gene expression of the microglia activation antigens mhc ii and cd11b, but not the astrocyte antigen gfap. |
2007-06-12 |
2023-08-12 |
Not clear |
| Marcus Ohlsson, Thao X Hoang, Jun Wu, Leif A Havto. Glial reactions in a rodent cauda equina injury and repair model. Experimental brain research. vol 170. issue 1. 2007-05-02. PMID:16328291. |
at 4 weeks postoperatively, immunohistochemistry using primary antibodies to gfap (astrocytes), ox-42 (microglia), and ed-1 (macrophages) was performed at the l6 spinal cord segment, and quantified using densitometry. |
2007-05-02 |
2023-08-12 |
rat |
| Rashmi Kumari, Lisa B Willing, J Kyle Krady, Susan J Vannucci, Ian A Simpso. Impaired wound healing after cerebral hypoxia-ischemia in the diabetic mouse. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 27. issue 4. 2007-04-19. PMID:16926846. |
in situ hybridization using bfl-1 (microglia) and glial fibrillary acidic protein (gfap) (astrocytes) revealed expression of both bfl-1 and gfap in the ipsilateral hemisphere at 4 h in the db/+ mice, which was delayed and minimal in the db/db mice. |
2007-04-19 |
2023-08-12 |
mouse |
| Milena Damjanac, Agnès Rioux Bilan, Laurence Barrier, Raymond Pontcharraud, Cantereau Anne, Jacques Hugon, Guylène Pag. Fluoro-Jade B staining as useful tool to identify activated microglia and astrocytes in a mouse transgenic model of Alzheimer's disease. Brain research. vol 1128. issue 1. 2007-03-27. PMID:17125750. |
in this study, we analyzed the staining of fluoro-jade b alone or combined with specific markers for detection of glial fibrillary acidic protein (gfap) or activated cd68 microglia in the double app(sl)/ps1 ki transgenic mice of alzheimer's disease (ad), which display a massive neuronal loss in the ca1 region of the hippocampus. |
2007-03-27 |
2023-08-12 |
mouse |
| Milena Damjanac, Agnès Rioux Bilan, Laurence Barrier, Raymond Pontcharraud, Cantereau Anne, Jacques Hugon, Guylène Pag. Fluoro-Jade B staining as useful tool to identify activated microglia and astrocytes in a mouse transgenic model of Alzheimer's disease. Brain research. vol 1128. issue 1. 2007-03-27. PMID:17125750. |
furthermore, fluoro-jade b was co-localized with cd68/macrosialin, a specific marker of activated microglia, and with gfap for astrocytes in app(sl)/ps1 ki transgenic mice of ad. |
2007-03-27 |
2023-08-12 |
mouse |
| Claudia Röhl, Ralph Lucius, Jobst Siever. The effect of activated microglia on astrogliosis parameters in astrocyte cultures. Brain research. vol 1129. issue 1. 2007-03-22. PMID:17169340. |
to examine the involvement of activated microglia in the onset and maintenance of astrogliosis, we used an in vitro model of purified cultures of astrocytes and assessed as parameters for astrogliosis gfap, vimentin, astroglial hypertrophy and cell growth after treatment with medium conditioned by lps (lipopolysaccarides)-stimulated microglia. |
2007-03-22 |
2023-08-12 |
Not clear |
| Derrick F MacFabe, Donald P Cain, Karina Rodriguez-Capote, Andrew E Franklin, Jennifer E Hoffman, Francis Boon, A Roy Taylor, Martin Kavaliers, Klaus-Peter Ossenkop. Neurobiological effects of intraventricular propionic acid in rats: possible role of short chain fatty acids on the pathogenesis and characteristics of autism spectrum disorders. Behavioural brain research. vol 176. issue 1. 2007-03-01. PMID:16950524. |
neurohistological examinations of hippocampus and adjacent white matter (external capsule) of ppa treated rats revealed increased reactive astrogliosis (gfap immunoreactivity) and activated microglia (cd68 immunoreactivity) suggestive of a neuroinflammatory process. |
2007-03-01 |
2023-08-12 |
human |
| Matthew G Frank, Michael V Baratta, David B Sprunger, Linda R Watkins, Steven F Maie. Microglia serve as a neuroimmune substrate for stress-induced potentiation of CNS pro-inflammatory cytokine responses. Brain, behavior, and immunity. vol 21. issue 1. 2007-02-22. PMID:16647243. |
the effect of inescapable shock (is) on glial activation (mhc ii, cd11b, iba-1, and gfap) and regulatory markers (cd200) in vivo, and microglia pro-inflammatory responses (interleukin-1beta; il-1beta) to lipopolysaccharide (lps) ex vivo, were assessed in rat hippocampus. |
2007-02-22 |
2023-08-12 |
rat |