| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Milena Damjanac, Agnès Rioux Bilan, Laurence Barrier, Raymond Pontcharraud, Cantereau Anne, Jacques Hugon, Guylène Pag. Fluoro-Jade B staining as useful tool to identify activated microglia and astrocytes in a mouse transgenic model of Alzheimer's disease. Brain research. vol 1128. issue 1. 2007-03-27. PMID:17125750. |
furthermore, fluoro-jade b was co-localized with cd68/macrosialin, a specific marker of activated microglia, and with gfap for astrocytes in app(sl)/ps1 ki transgenic mice of ad. |
2007-03-27 |
2023-08-12 |
mouse |
| Claudia Röhl, Ralph Lucius, Jobst Siever. The effect of activated microglia on astrogliosis parameters in astrocyte cultures. Brain research. vol 1129. issue 1. 2007-03-22. PMID:17169340. |
to examine the involvement of activated microglia in the onset and maintenance of astrogliosis, we used an in vitro model of purified cultures of astrocytes and assessed as parameters for astrogliosis gfap, vimentin, astroglial hypertrophy and cell growth after treatment with medium conditioned by lps (lipopolysaccarides)-stimulated microglia. |
2007-03-22 |
2023-08-12 |
Not clear |
| Derrick F MacFabe, Donald P Cain, Karina Rodriguez-Capote, Andrew E Franklin, Jennifer E Hoffman, Francis Boon, A Roy Taylor, Martin Kavaliers, Klaus-Peter Ossenkop. Neurobiological effects of intraventricular propionic acid in rats: possible role of short chain fatty acids on the pathogenesis and characteristics of autism spectrum disorders. Behavioural brain research. vol 176. issue 1. 2007-03-01. PMID:16950524. |
neurohistological examinations of hippocampus and adjacent white matter (external capsule) of ppa treated rats revealed increased reactive astrogliosis (gfap immunoreactivity) and activated microglia (cd68 immunoreactivity) suggestive of a neuroinflammatory process. |
2007-03-01 |
2023-08-12 |
human |
| Matthew G Frank, Michael V Baratta, David B Sprunger, Linda R Watkins, Steven F Maie. Microglia serve as a neuroimmune substrate for stress-induced potentiation of CNS pro-inflammatory cytokine responses. Brain, behavior, and immunity. vol 21. issue 1. 2007-02-22. PMID:16647243. |
the effect of inescapable shock (is) on glial activation (mhc ii, cd11b, iba-1, and gfap) and regulatory markers (cd200) in vivo, and microglia pro-inflammatory responses (interleukin-1beta; il-1beta) to lipopolysaccharide (lps) ex vivo, were assessed in rat hippocampus. |
2007-02-22 |
2023-08-12 |
rat |
| Matthew G Frank, Michael V Baratta, David B Sprunger, Linda R Watkins, Steven F Maie. Microglia serve as a neuroimmune substrate for stress-induced potentiation of CNS pro-inflammatory cytokine responses. Brain, behavior, and immunity. vol 21. issue 1. 2007-02-22. PMID:16647243. |
is upregulated the microglia activation marker mhc ii 24h post-is, while the astroglia marker gfap was unaffected. |
2007-02-22 |
2023-08-12 |
rat |
| Shaji Theodore, Stephanie Stolberg, Wayne A Cass, William F Marago. Human immunodeficiency virus-1 protein tat and methamphetamine interactions. Annals of the New York Academy of Sciences. vol 1074. 2007-01-10. PMID:17105916. |
we have also examined the glial reaction using gfap as a marker of astrocyte activation and ox-42 as a marker of activated microglia. |
2007-01-10 |
2023-08-12 |
human |
| Vadim S Polikov, Michelle L Block, Jean-Marc Fellous, Jau-Shyong Hong, W Monty Reicher. In vitro model of glial scarring around neuroelectrodes chronically implanted in the CNS. Biomaterials. vol 27. issue 31. 2006-10-17. PMID:16842846. |
the chronic presence of microwire resulted in a glial scar forming at 10 days, with microglia forming an inner layer of cells coating the microwire, while astrocytes surrounded the microglial core with a network of cellular processes containing upregulated gfap. |
2006-10-17 |
2023-08-12 |
rat |
| P M Rappold, E Lynd-Balta, S A Josep. P2X7 receptor immunoreactive profile confined to resting and activated microglia in the epileptic brain. Brain research. vol 1089. issue 1. 2006-09-08. PMID:16635480. |
specific glial markers tested in the series included iba1 (microglia), cox-1 (microglia), and gfap (astroglia). |
2006-09-08 |
2023-08-12 |
rat |
| Ming Qin, Jing-Jie Wang, Rong Cao, Hui Zhang, Li Duan, Bei Gao, Ying-Fei Xiong, Liang-Wei Chen, Zhi-Ren Ra. The lumbar spinal cord glial cells actively modulate subcutaneous formalin induced hyperalgesia in the rat. Neuroscience research. vol 55. issue 4. 2006-09-08. PMID:16759728. |
it was demonstrated that fos/neun immunoreactive (-ir) neurons, glial fibrillary acidic protein (gfap)-ir astrocytes and ox42-ir microglia were distributed in dorsal horn of lumbar spinal cord, predominantly in the superficial layer. |
2006-09-08 |
2023-08-12 |
rat |
| William L Maxwell, Mary Anne MacKinnon, Douglas H Smith, Tracy K McIntosh, David I Graha. Thalamic nuclei after human blunt head injury. Journal of neuropathology and experimental neurology. vol 65. issue 5. 2006-07-26. PMID:16772871. |
neurons, astrocytes, macrophages, and activated microglia were differentiated by luxol fast blue/cresyl violet, gfap, cd68, and cr3/43 staining and stereological techniques used to estimate cell number in a 28-microm-thick coronal section. |
2006-07-26 |
2023-08-12 |
human |
| Minoru Narita, Takuya Yoshida, Mayumi Nakajima, Michiko Narita, Mayumi Miyatake, Tomoe Takagi, Yoshinori Yajima, Tsutomu Suzuk. Direct evidence for spinal cord microglia in the development of a neuropathic pain-like state in mice. Journal of neurochemistry. vol 97. issue 5. 2006-07-21. PMID:16606373. |
furthermore, 5-bromo-2'-deoxyuridine (brdu)-positive cells on the ipsilateral dorsal horn of the spinal cord were significantly increased at 7 days after nerve ligation and were highly co-localized with another microglia marker, ionized calcium-binding adaptor molecule 1 (iba1), but neither with gfap nor a specific neural nuclei marker, neun, in the spinal dorsal horn of nerve-ligated mice. |
2006-07-21 |
2023-08-12 |
mouse |
| Rui-Xin Zhang, Bing Liu, Linbo Wang, Ke Ren, Jian-Tian Qiao, Brian M Berman, Lixing La. Spinal glial activation in a new rat model of bone cancer pain produced by prostate cancer cell inoculation of the tibia. Pain. vol 118. issue 1-2. 2006-07-06. PMID:16154703. |
the results showed that: (1) inoculation of prostate cancer cells, but not the vehicle hank's solution, induced progressive bone destruction at the proximal epiphysis of the tibia from day 7-20 post inoculation; (2) the inoculation also induced progressive thermal hyperalgesia, mechanical hyperalgesia, mechanical allodynia, and spontaneous flinches; (3) astrocytes and microglia were significantly activated in the spinal cord ipsilateral to the cancer leg, characterized by enhanced immunostaining of both glial fibrillary acidic protein (gfap, astrocyte marker) and ox-42 (microglial marker); (4) il-1beta was up-regulated in the ipsilateral spinal cord, evidenced by an increase of il-1beta immunostained astrocytes. |
2006-07-06 |
2023-08-12 |
rat |
| Zheng Gen Piao, Ik-Hyun Cho, Chul Kyu Park, Jin Pyo Hong, Se-Young Choi, Sung Joong Lee, Seungbok Lee, Kyungpyo Park, Joong Soo Kim, Seog Bae O. Activation of glia and microglial p38 MAPK in medullary dorsal horn contributes to tactile hypersensitivity following trigeminal sensory nerve injury. Pain. vol 121. issue 3. 2006-06-22. PMID:16495005. |
activation of microglia and astrocytes was monitored at 2 h, 1, 3, 7, 14, 28, and 60 days using immunohistochemical analysis with ox-42 and gfap antibodies, respectively. |
2006-06-22 |
2023-08-12 |
Not clear |
| Stanley Anthony Benkovic, James Patrick O'Callaghan, Diane Bemis Mille. Regional neuropathology following kainic acid intoxication in adult and aged C57BL/6J mice. Brain research. vol 1070. issue 1. 2006-06-06. PMID:16403473. |
histochemical evaluation of gfap and lectin staining revealed activation of astrocytes and microglia in regions with corresponding argyrophilia. |
2006-06-06 |
2023-08-12 |
mouse |
| Donna L Herber, Jessica L Maloney, Lisa M Roth, Melissa J Freeman, Dave Morgan, Marcia N Gordo. Diverse microglial responses after intrahippocampal administration of lipopolysaccharide. Glia. vol 53. issue 4. 2006-04-04. PMID:16288481. |
significant elevations of cluster differentiation marker cd45, glial fibrillary acidic protein (gfap), scavenger receptor a (sra), and fcgamma receptor mrna were seen after 24 h. immunohistochemistry revealed a complex pattern of protein expression by microglia, as well as changes in cell morphologies. |
2006-04-04 |
2023-08-12 |
mouse |
| Jing-Hui Dong, Guo-Xin Ying, Xin Liu, Wen-Yuan Wang, Yan Wang, Zi-Mei Ni, Chang-Fu Zho. Lesion-induced gelsolin upregulation in the hippocampus following entorhinal deafferentation. Hippocampus. vol 16. issue 1. 2006-03-02. PMID:16261560. |
double labeling of either gelsolin mrna or protein with markers of glial cells (griffonia simplicifolia ib4 and cd11b for microglial cells, gfap for astroglial cells) revealed that gelsolin was highly expressed by both activated microglia and astrocytes. |
2006-03-02 |
2023-08-12 |
Not clear |
| Han Kyu Lee, Young Jun Seo, Seong Soo Choi, Min Soo Kwon, Eon Jeong Shim, Jin Young Lee, Hong Won Su. Role of gamma-aminobutyricacidB(GABA(B)) receptors in the regulation of kainic acid-induced cell death in mouse hippocampus. Experimental & molecular medicine. vol 37. issue 6. 2006-02-01. PMID:16391514. |
activated astrocytes, which was presented by gfap ir, and activated microglia, which was presented by the ox-42 ir, may be a good indicator for measuring the cell death in hippocampal regions by ka excitotoxicity. |
2006-02-01 |
2023-08-12 |
mouse |
| Alexander Semmler, Torsten Okulla, Magdalena Sastre, Lucia Dumitrescu-Ozimek, Michael T Henek. Systemic inflammation induces apoptosis with variable vulnerability of different brain regions. Journal of chemical neuroanatomy. vol 30. issue 2-3. 2006-01-25. PMID:16122904. |
immunohistochemical evaluation revealed a sepsis-induced, time-dependent increase in the immunoreactivity of inos, glial fibrillary acidic protein (gfap) and activated microglia (ed-1), paralleled by a time-dependent increase of apoptotic brain cells marked by terminal deoxynucleotidyl transferase-mediated dutp-nick end labeling (tunel), an increase of bax-positive cells and a decrease of bcl-2-positive cells. |
2006-01-25 |
2023-08-12 |
rat |
| Purnima P Desai, Milos D Ikonomovic, Eric E Abrahamson, Ronald L Hamilton, Barbara A Isanski, Caroline E Hope, William E Klunk, Steven T DeKosky, M Ilyas Kambo. Apolipoprotein D is a component of compact but not diffuse amyloid-beta plaques in Alzheimer's disease temporal cortex. Neurobiology of disease. vol 20. issue 2. 2006-01-23. PMID:15916898. |
apod-immunoreactive cells within plaques morphologically matched mhc-ii- and cd-68-immunoreactive microglia, and did not contain the astrocytic marker gfap, which labeled a subset of apod-immunoreactive cells surrounding plaques. |
2006-01-23 |
2023-08-12 |
Not clear |
| Mahmoud M Iravani, Clement C M Leung, Mona Sadeghian, Claire O Haddon, Sarah Rose, Peter Jenne. The acute and the long-term effects of nigral lipopolysaccharide administration on dopaminergic dysfunction and glial cell activation. The European journal of neuroscience. vol 22. issue 2. 2005-09-23. PMID:16045485. |
at 24 h, there was a moderate increase in glial fibrillary acidic protein (gfap)-ir astrocytes in the sn but a marked elevation of p47phox positive ox-42-ir microglia, and intense inducible nitric oxide synthase (inos)-ir and 3-nitrotyrosine (3-nt)-ir was present. |
2005-09-23 |
2023-08-12 |
human |