| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Konrad Mader, Jonas Andermahr, Doychin N Angelov, Wolfram F Neis. Dual mode of signalling of the axotomy reaction: retrograde electric stimulation or block of retrograde transport differently mimic the reaction of motoneurons to nerve transection in the rat brainstem. Journal of neurotrauma. vol 21. issue 7. 2004-09-23. PMID:15307907. |
nerve resection activated microglia at 2-35 days post-operation (dpo), elevated gfap in astrocytes at 3-35 dpo and increased cgrp in motoneurons at 2-15 dpo. |
2004-09-23 |
2023-08-12 |
rat |
| Konrad Mader, Jonas Andermahr, Doychin N Angelov, Wolfram F Neis. Dual mode of signalling of the axotomy reaction: retrograde electric stimulation or block of retrograde transport differently mimic the reaction of motoneurons to nerve transection in the rat brainstem. Journal of neurotrauma. vol 21. issue 7. 2004-09-23. PMID:15307907. |
colchicine block similarly activated microglia at 5-35 dpo, elevated gfap at 7-35 dpo and upregulated cgrp at 7-25 dpo. |
2004-09-23 |
2023-08-12 |
rat |
| Young-Tae Kim, Robert W Hitchcock, Michael J Bridge, Patrick A Tresc. Chronic response of adult rat brain tissue to implants anchored to the skull. Biomaterials. vol 25. issue 12. 2004-09-14. PMID:14741588. |
we found that the reaction surrounding transcranially implanted hfms was significantly greater than that observed with intraparenchymally implanted materials including increases in immunoreactivity against gfap, vimentin, ed-1 labeled macrophages and microglia, and several extracellular matrix proteins including collagen, fibronectin, and laminin. |
2004-09-14 |
2023-08-12 |
rat |
| M M Ahmed, H Hoshino, T Chikuma, M Yamada, T Kat. Effect of memantine on the levels of glial cells, neuropeptides, and peptide-degrading enzymes in rat brain regions of ibotenic acid-treated alzheimer's disease model. Neuroscience. vol 126. issue 3. 2004-09-14. PMID:15183513. |
furthermore, the immunohistochemical and enzymatic studies of gfap and cd 11b, and peptidylarginine deiminase, markers of glia, in the striatum and frontal cortex showed the increase in ibo-treated rat brain as compared with controls, while co-administration of memantine and ibo no increase of astrocytes and microglia activation was observed. |
2004-09-14 |
2023-08-12 |
rat |
| Ru Ping Dai, Bei Ping He, S Thameem Dheen, Samuel Sam Wah Ta. Acute cardiac injury induces glial cell response and activates extracellular signaling-regulated kinase-1 and -2 in the spinal cord of Wistar rats. Neuroscience letters. vol 366. issue 1. 2004-08-26. PMID:15265585. |
following aci, the astrocytes (determined by glial fibrillary acidic protein (gfap) immunoreactivity (-ir)) and microglia (determined by ox-42-ir) were activated within the thoracic spinal cord. |
2004-08-26 |
2023-08-12 |
rat |
| Francesca R Fusco, Alessandro Martorana, Carmela Giampà, Zena De March, Fabrizio Vacca, Alessandro Tozzi, Patrizia Longone, Silvia Piccirilli, Stefano Paolucci, Giuseppe Sancesario, Nicola B Mercuri, Giorgio Bernard. Cellular localization of TRPC3 channel in rat brain: preferential distribution to oligodendrocytes. Neuroscience letters. vol 365. issue 2. 2004-08-09. PMID:15245795. |
we performed a double labeling study for trpc3 and one of the following cell-specific markers: mouse anti-glial fibrillary acidic protein (gfap) for astrocytes; mouse anti-rip for oligodendrocytes, or mouse anti-ox42 for microglia, or mouse anti-neun for neuronal nuclei or mouse anti-tyrosine hydroxylase (th) for detection of dopaminergic neurons of the substantia nigra. |
2004-08-09 |
2023-08-12 |
mouse |
| Ming-Kai Chen, Kwamena Baidoo, Tatyana Verina, Tomás R Guilart. Peripheral benzodiazepine receptor imaging in CNS demyelination: functional implications of anatomical and cellular localization. Brain : a journal of neurology. vol 127. issue Pt 6. 2004-07-13. PMID:15069023. |
quantitative autoradiography of the pbr-selective ligand [(3)h]-(r)-pk11195 and [(125)i]-(r)-pk11195 showed that increased pbr levels were associated with the degree of demyelination assessed by black-gold histochemistry and activation of glial cells assessed by glial fibrillary acidic protein (gfap) immunohistochemistry for astrocytes and cd11b (mac-1) for microglia. |
2004-07-13 |
2023-08-12 |
mouse |
| Ming-Kai Chen, Kwamena Baidoo, Tatyana Verina, Tomás R Guilart. Peripheral benzodiazepine receptor imaging in CNS demyelination: functional implications of anatomical and cellular localization. Brain : a journal of neurology. vol 127. issue Pt 6. 2004-07-13. PMID:15069023. |
high-resolution emulsion autoradiography of [(3)h]-(r)-pk11195 binding to pbr coupled with gfap or mac-1 immunohistochemistry showed that demyelination-induced increases in pbr levels were co-localized to both microglia and astrocytes. |
2004-07-13 |
2023-08-12 |
mouse |
| Boris Ferger, Andreas Leng, Anna Mura, Bastian Hengerer, Joram Feldo. Genetic ablation of tumor necrosis factor-alpha (TNF-alpha) and pharmacological inhibition of TNF-synthesis attenuates MPTP toxicity in mouse striatum. Journal of neurochemistry. vol 89. issue 4. 2004-06-04. PMID:15140182. |
real-time rt-pcr revealed that the striatal mrna levels of tnf-alpha, of the astrocytic marker glial fibrillary acidic protein (gfap) and of the marker for activated microglia, macrophage antigen complex-1 (mac-1), were significantly enhanced after mptp administration. |
2004-06-04 |
2023-08-12 |
mouse |
| Michel Baudry, Yuequin Yao, Danielle Simmons, Jihua Liu, Xiaoning B. Postnatal development of inflammation in a murine model of Niemann-Pick type C disease: immunohistochemical observations of microglia and astroglia. Experimental neurology. vol 184. issue 2. 2004-04-02. PMID:14769381. |
brain sections from npc1-/- and wild-type (npc1+/+) mice were immunostained with the mac1 antibody, which recognizes microglia, with antibodies against glial fibrillary acidic protein (gfap), which recognize astrocytes, and with antibodies against the cytokine interleukin-1beta (il-1beta). |
2004-04-02 |
2023-08-12 |
mouse |
| Thad A Rosenberger, Nelly E Villacreses, Jonathan T Hovda, Francesca Bosetti, Gayani Weerasinghe, Robert N Wine, G Jean Harry, Stanley I Rapopor. Rat brain arachidonic acid metabolism is increased by a 6-day intracerebral ventricular infusion of bacterial lipopolysaccharide. Journal of neurochemistry. vol 88. issue 5. 2004-03-30. PMID:15009672. |
the 6-day intracerebral ventricular infusion increased lectin-reactive microglia in the cerebral ventricles, pia mater, and the glial membrane of the cortex and resulted in morphological changes of glial fibrillary acidic protein (gfap)-positive astrocytes in the cortical mantel and areas surrounding the cerebral ventricles. |
2004-03-30 |
2023-08-12 |
rat |
| R W P Rodrigues, V C Gomide, G Chad. Astroglial and microglial activation in the wistar rat ventral tegmental area after a single striatal injection of 6-hydroxydopamine. The International journal of neuroscience. vol 114. issue 2. 2004-03-15. PMID:14702208. |
the tyrosine hydroxylase (th) positive dopamine cells, the glial fibrillary acidic protein (gfap) immuno -labeled astrocytes, and the ox42 immunoreactive microglia were visualized by means of immunohistochemistry and quantified by stereologic methods employing the optical dissector and the point intercepts. |
2004-03-15 |
2023-08-12 |
rat |
| C A Davies, H Gollins, N Stevens, A P Fotheringham, I Davie. The glial cell response to a viral vector in the aged brain. Neuropathology and applied neurobiology. vol 30. issue 1. 2004-03-10. PMID:14720174. |
after 48 h, the mice were killed and the brains analysed for numbers of activated microglia and macrophages using the biotinylated lectin griffonia simplicifolia as a marker; astroglia were identified by immunohistochemistry for glial fibrillary acidic protein (gfap). |
2004-03-10 |
2023-08-12 |
mouse |
| Michael G Drage, Gregory L Holmes, Thomas N Seyfrie. Hippocampal neurons and glia in epileptic EL mice. Journal of neurocytology. vol 31. issue 8-9. 2004-02-26. PMID:14501207. |
immunostaining for glial fibrillary acidic protein (gfap) and iba1, an actin cross-linking molecule restricted to macrophages and microglia, was used to evaluate astrocytes and microglia, respectively. |
2004-02-26 |
2023-08-12 |
mouse |
| D H Szarowski, M D Andersen, S Retterer, A J Spence, M Isaacson, H G Craighead, J N Turner, W Shai. Brain responses to micro-machined silicon devices. Brain research. vol 983. issue 1-2. 2003-11-28. PMID:12914963. |
tissues were immunochemically labeled for glial fibrillary acidic protein (gfap) or vimentin to identify astrocytes, or for ed1 to identify microglia. |
2003-11-28 |
2023-08-12 |
Not clear |
| Steven W Levison, Stuart K Druckman, Greg M Young, Anirban Bas. Neural stem cells in the subventricular zone are a source of astrocytes and oligodendrocytes, but not microglia. Developmental neuroscience. vol 25. issue 2-4. 2003-10-30. PMID:12966216. |
of 130 clones examined, where we used triple immunofluorescence with antibodies that recognize microglia, 2 clonal clusters contained ox-42+ microglia that were retrovirally labeled, but all of the cells in those clones expressed the microglial marker and none expressed either gfap or o4. |
2003-10-30 |
2023-08-12 |
human |
| M Tortarolo, P Veglianese, N Calvaresi, A Botturi, C Rossi, A Giorgini, A Migheli, C Bendott. Persistent activation of p38 mitogen-activated protein kinase in a mouse model of familial amyotrophic lateral sclerosis correlates with disease progression. Molecular and cellular neurosciences. vol 23. issue 2. 2003-09-30. PMID:12812752. |
as the disease progressed, activated p38mapk also accumulated in hypertrophic astrocytes and reactive microglia, as demonstrated by colocalization with gfap and cd11b immunostaining, respectively. |
2003-09-30 |
2023-08-12 |
mouse |
| K E Rhodes, L D F Moon, J W Fawcet. Inhibiting cell proliferation during formation of the glial scar: effects on axon regeneration in the CNS. Neuroscience. vol 120. issue 1. 2003-09-30. PMID:12849739. |
almost complete elimination of ng2 oligodendrocyte progenitor cells from the lesion site was seen up to 7 dpl in arac-infused animals; reduced numbers of reactive cd11b microglia were also seen but no effects were seen on the injury response of gfap astrocytes. |
2003-09-30 |
2023-08-12 |
rat |
| Alicia A Babcock, William A Kuziel, Serge Rivest, Trevor Owen. Chemokine expression by glial cells directs leukocytes to sites of axonal injury in the CNS. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 21. 2003-09-16. PMID:12944523. |
in situ hybridization combined with immunohistochemistry for ionized binding calcium adapter molecule (iba)1 or glial fibrillary acidic protein (gfap) identified iba1+ microglia and gfap+ astrocytes as major sources of mcp-1/ccl2 within the lesion-reactive hippocampus. |
2003-09-16 |
2023-08-12 |
mouse |
| David A Bechtold, Ian R Brow. Induction of Hsp27 and Hsp32 stress proteins and vimentin in glial cells of the rat hippocampus following hyperthermia. Neurochemical research. vol 28. issue 8. 2003-09-03. PMID:12834255. |
a pronounced induction of these low-molecular-weight stress proteins was apparent in populations of glial cells such as astrocytes and microglia that were identified using cell-specific markers (gfap for astrocytes and the lectin gsa i-b4 for microglia). |
2003-09-03 |
2023-08-12 |
rat |