| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Pavía, M L de Ceballos, F Sanchez de la Cuest. Alzheimer's disease: relationship between muscarinic cholinergic receptors, beta-amyloid and tau proteins. Fundamental & clinical pharmacology. vol 12. issue 5. 1998-12-22. PMID:9794144. |
the existence of a link between beta-amyloid and tau proteins also has been reported; treatment of hippocampal neurones with beta-amyloid, or the 25-35 residue fragment, resulted in an increase in tau protein phosphorylation. |
1998-12-22 |
2023-08-12 |
human |
| C Duyckaerts, M A Colle, F Dessi, Y Grignon, F Piette, J J Hau. The progression of the lesions in Alzheimer disease: insights from a prospective clinicopathological study. Journal of neural transmission. Supplementum. vol 53. 1998-11-12. PMID:9700650. |
in the isocortex, the progression of the tau positive alterations is, on the contrary, stepwise--in a "all or none" fashion--from the hippocampus to the primary cortices, through the associative multimodal areas. |
1998-11-12 |
2023-08-12 |
Not clear |
| S L Kwei, A Clement, A Faissner, R Brand. Differential interactions of MAP2, tau and MAP5 during axogenesis in culture. Neuroreport. vol 9. issue 6. 1998-08-13. PMID:9601663. |
the subcellular interactions of the neuronal microtubule-associated proteins tau, map2 and map5 were determined in cultured rat hippocampal neurons using differential detergent extraction and laser scanning microscopy. |
1998-08-13 |
2023-08-12 |
rat |
| C K Combs, P D Coleman, M K O'Banio. Developmental regulation and PKC dependence of Alzheimer's-type tau phosphorylations in cultured fetal rat hippocampal neurons. Brain research. Developmental brain research. vol 107. issue 1. 1998-07-27. PMID:9602100. |
developmental regulation and pkc dependence of alzheimer's-type tau phosphorylations in cultured fetal rat hippocampal neurons. |
1998-07-27 |
2023-08-12 |
rat |
| C K Combs, P D Coleman, M K O'Banio. Developmental regulation and PKC dependence of Alzheimer's-type tau phosphorylations in cultured fetal rat hippocampal neurons. Brain research. Developmental brain research. vol 107. issue 1. 1998-07-27. PMID:9602100. |
using fetal rat hippocampal cultures, we report a spatial and temporal expression of tau phosphorylation during neuronal differentiation. |
1998-07-27 |
2023-08-12 |
rat |
| K Imahori, M Hoshi, K Ishiguro, K Sato, M Takahashi, R Shiurba, H Yamaguchi, A Takashima, T Uchid. Possible role of tau protein kinases in pathogenesis of Alzheimer's disease. Neurobiology of aging. vol 19. issue 1 Suppl. 1998-06-12. PMID:9562476. |
such up-regulation of tpki and phosphorylatioin of tau were reproduced by treating cultured hippocampal cells with amyloid beta (abeta) protein. |
1998-06-12 |
2023-08-12 |
Not clear |
| B A Bahr, J S Vicent. Age-related phosphorylation and fragmentation events influence the distribution profiles of distinct tau isoforms in mouse brain. Journal of neuropathology and experimental neurology. vol 57. issue 2. 1998-06-08. PMID:9600203. |
the hippocampus and neocortex had concentrated levels of 55 kda tau, and moderate amounts of 62-69 kda isoforms. |
1998-06-08 |
2023-08-12 |
mouse |
| B A Bahr, J S Vicent. Age-related phosphorylation and fragmentation events influence the distribution profiles of distinct tau isoforms in mouse brain. Journal of neuropathology and experimental neurology. vol 57. issue 2. 1998-06-08. PMID:9600203. |
when assessing hippocampal tau across age, increasing levels of 69 kda tau were found to correlate with a gradual reduction in 42-50 kda isoforms. |
1998-06-08 |
2023-08-12 |
mouse |
| J Collet, L Fehrat, H Pollard, L Ribas de Pouplana, G Charton, A Bernard, J Moreau, Y Ben-Ari, M Khrestchatisk. Developmentally regulated alternative splicing of mRNAs encoding N-terminal tau variants in the rat hippocampus: structural and functional implications. The European journal of neuroscience. vol 9. issue 12. 1998-04-24. PMID:9517477. |
developmentally regulated alternative splicing of mrnas encoding n-terminal tau variants in the rat hippocampus: structural and functional implications. |
1998-04-24 |
2023-08-12 |
rat |
| J Collet, L Fehrat, H Pollard, L Ribas de Pouplana, G Charton, A Bernard, J Moreau, Y Ben-Ari, M Khrestchatisk. Developmentally regulated alternative splicing of mRNAs encoding N-terminal tau variants in the rat hippocampus: structural and functional implications. The European journal of neuroscience. vol 9. issue 12. 1998-04-24. PMID:9517477. |
we studied the expression of the mrnas encoding n-terminal variants of tau, and we showed distinct alternative splicing of exons 2 and 3 in nervous tissues of the adult rat, including the inner ear, hippocampus, cortex, striatum, brainstem, cerebellum, olfactory bulb and retina. |
1998-04-24 |
2023-08-12 |
rat |
| J Collet, L Fehrat, H Pollard, L Ribas de Pouplana, G Charton, A Bernard, J Moreau, Y Ben-Ari, M Khrestchatisk. Developmentally regulated alternative splicing of mRNAs encoding N-terminal tau variants in the rat hippocampus: structural and functional implications. The European journal of neuroscience. vol 9. issue 12. 1998-04-24. PMID:9517477. |
using the reverse transcriptase-coupled polymerase chain reaction and in situ hybridization, we then focused our developmental study on hippocampal neurons, both in vivo and in vitro, to address the developmental and spatial expression of the alternatively spliced mrnas encoding n-terminal variants of tau. |
1998-04-24 |
2023-08-12 |
rat |
| J Collet, L Fehrat, H Pollard, L Ribas de Pouplana, G Charton, A Bernard, J Moreau, Y Ben-Ari, M Khrestchatisk. Developmentally regulated alternative splicing of mRNAs encoding N-terminal tau variants in the rat hippocampus: structural and functional implications. The European journal of neuroscience. vol 9. issue 12. 1998-04-24. PMID:9517477. |
the timing and pattern of tau alternative splicing were maintained in cultured hippocampal neurons, suggesting that splicing processes are independent of the organized connectivity and of the environmental cues provided in vivo. |
1998-04-24 |
2023-08-12 |
rat |
| A Ferreira, Q Lu, L Orecchio, K S Kosi. Selective phosphorylation of adult tau isoforms in mature hippocampal neurons exposed to fibrillar A beta. Molecular and cellular neurosciences. vol 9. issue 3. 1997-10-27. PMID:9245504. |
selective phosphorylation of adult tau isoforms in mature hippocampal neurons exposed to fibrillar a beta. |
1997-10-27 |
2023-08-12 |
rat |
| A Ferreira, Q Lu, L Orecchio, K S Kosi. Selective phosphorylation of adult tau isoforms in mature hippocampal neurons exposed to fibrillar A beta. Molecular and cellular neurosciences. vol 9. issue 3. 1997-10-27. PMID:9245504. |
we characterized a hippocampal neuronal culture system in which tau undergoes maturation in vivo; rat neurons maintained in culture for more than 3 weeks replicated the splicing and phosphorylation changes that tau undergoes upon maturation in situ. |
1997-10-27 |
2023-08-12 |
rat |
| M P Mattson, W Fu, G Waeg, K Uchid. 4-Hydroxynonenal, a product of lipid peroxidation, inhibits dephosphorylation of the microtubule-associated protein tau. Neuroreport. vol 8. issue 9-10. 1997-10-07. PMID:9243625. |
we now report that following exposure of cultured rat hippocampal neurons to 4-hydroxynonenal (hne), an aldehydic product of membrane lipid peroxidation, tau is resistant to dephosphorylation. |
1997-10-07 |
2023-08-12 |
rat |
| P Giannakopoulos, S Silhol, V Jallageas, J Mallet, N Bons, C Bouras, P Delaèr. Quantitative analysis of tau protein-immunoreactive accumulations and beta amyloid protein deposits in the cerebral cortex of the mouse lemur, Microcebus murinus. Acta neuropathologica. vol 94. issue 2. 1997-09-17. PMID:9255387. |
the age-dependent progression of tau protein-immunoreactive accumulations indicates that this prosimian may represent a valuable model for the study of the biochemical mechanisms of brain aging, while the relative sparing of hippocampus in mouse lemurs contrasts sharply with previous reports on neurofibrillary tangle formation in humans, and suggests that this animal may also be useful to investigate the biological characteristics of neuroprotection in this area. |
1997-09-17 |
2023-08-12 |
mouse |
| K Sugaya, M Reeves, M McKinne. Topographic associations between DNA fragmentation and Alzheimer's disease neuropathology in the hippocampus. Neurochemistry international. vol 31. issue 2. 1997-09-02. PMID:9220460. |
to identify whether the process of apoptosis bears a topographic relationship to selected aspects of alzheimer's disease (ad) pathology, we used an in situ nick translation method (tunel) to map dna fragmentation in hippocampal sections immunostained for abnormally phosphorylated tau, which exists in the neurofibrillary tangles (nfts) and in the dystrophic neurites associated with senile plaques. |
1997-09-02 |
2023-08-12 |
human |
| F Malchiodi-Albedi, T C Petrucci, B Picconi, F Iosi, M Falch. Protein phosphatase inhibitors induce modification of synapse structure and tau hyperphosphorylation in cultured rat hippocampal neurons. Journal of neuroscience research. vol 48. issue 5. 1997-07-28. PMID:9185666. |
protein phosphatase inhibitors induce modification of synapse structure and tau hyperphosphorylation in cultured rat hippocampal neurons. |
1997-07-28 |
2023-08-12 |
rat |
| E A Irving, J McCulloch, D Dewa. The effect of postmortem delay on the distribution of microtubule-associated proteins tau, MAP2, and MAP5 in the rat. Molecular and chemical neuropathology. vol 30. issue 3. 1997-07-18. PMID:9165490. |
in this study, the distribution of tau, map2, and map5 immunohistochemistry was examined following postmortem intervals of 0-72 h in the rat cerebral cortex, corpus callosum, caudate nucleus, and hippocampus. |
1997-07-18 |
2023-08-12 |
human |
| K Imahori, T Uchid. Physiology and pathology of tau protein kinases in relation to Alzheimer's disease. Journal of biochemistry. vol 121. issue 2. 1997-07-11. PMID:9089387. |
when a primary culture of embryonic rat hippocampus was treated with 20 microm a beta, induction of tpki, extensive phosphorylation of tau and then programmed cell death were observed, indicating that tpki induced by a beta phosphorylates tau, followed by disruption of axonal transportation and finally cell death. |
1997-07-11 |
2023-08-12 |
rat |