| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C F Lippa, T W Smit. The indusium griseum in Alzheimer's disease: an immunocytochemical study. Journal of the neurological sciences. vol 111. issue 1. 1992-11-12. PMID:1328542. |
numerous alz-50, tau and ubiquitin-positive neurofibrillary tangles and dystrophic neurites were observed in the ad hippocampus but were infrequent in the ig. |
1992-11-12 |
2023-08-11 |
Not clear |
| S Simler, L Ciesielski, J Clement, A Rastegar, P Mande. Involvement of synaptosomal neurotransmitter amino acids in audiogenic seizure-susceptibility and -severity of Rb mice. Neurochemical research. vol 17. issue 9. 1992-11-02. PMID:1357566. |
low levels of tau, gaba, and ser in hippocampus, gly in amygdala, glu in hippocampus, inferior colliculus and pons, gln and asp in inferior colliculus appeared to correlate with seizure-susceptibility. |
1992-11-02 |
2023-08-11 |
mouse |
| S Simler, L Ciesielski, J Clement, A Rastegar, P Mande. Involvement of synaptosomal neurotransmitter amino acids in audiogenic seizure-susceptibility and -severity of Rb mice. Neurochemical research. vol 17. issue 9. 1992-11-02. PMID:1357566. |
a strong involvement of hippocampus (tau, gaba, ser, glu, and gln) and inferior colliculus (asp, glu, gln) in audiogenic seizure-susceptibility, and of olfactory bulb (gaba, asp) in seizure-severity and/or -diversity is suggested. |
1992-11-02 |
2023-08-11 |
mouse |
| M P Mattso. Effects of microtubule stabilization and destabilization on tau immunoreactivity in cultured hippocampal neurons. Brain research. vol 582. issue 1. 1992-09-14. PMID:1354011. |
effects of microtubule stabilization and destabilization on tau immunoreactivity in cultured hippocampal neurons. |
1992-09-14 |
2023-08-11 |
human |
| M P Mattso. Effects of microtubule stabilization and destabilization on tau immunoreactivity in cultured hippocampal neurons. Brain research. vol 582. issue 1. 1992-09-14. PMID:1354011. |
previous data indicated that calcium influx can cause antigenic changes in tau in cultured rat hippocampal and human cortical neurons similar to those seen in nft. |
1992-09-14 |
2023-08-11 |
human |
| M P Mattso. Effects of microtubule stabilization and destabilization on tau immunoreactivity in cultured hippocampal neurons. Brain research. vol 582. issue 1. 1992-09-14. PMID:1354011. |
the present study used cultured hippocampal neurons to test the hypothesis that disruption of microtubules is a key event leading to altered antigenic properties of tau that result from calcium influx. |
1992-09-14 |
2023-08-11 |
human |
| K Kolasa, R S Jope, M S Baird, G V Johnso. Alterations of choline acetyltransferase, phosphoinositide hydrolysis, and cytoskeletal proteins in rat brain in response to colchicine administration. Experimental brain research. vol 89. issue 3. 1992-09-08. PMID:1322821. |
the concentrations of tau and tubulin in the hippocampus were unaltered by colchicine treatment, and map-2 and spectrin were only slightly reduced 4 weeks after colchicine. |
1992-09-08 |
2023-08-11 |
rat |
| H Arai, M L Schmidt, V M Lee, H I Hurtig, B D Greenberg, C H Adler, J Q Trojanowsk. Epitope analysis of senile plaque components in the hippocampus of patients with Parkinson's disease. Neurology. vol 42. issue 7. 1992-08-06. PMID:1377804. |
as in the ad hippocampus, the sps detected by conventional stains in five of the 10 demented subjects contained the beta-ap and flanking domains in beta-apps as well as epitopes in tau, neurofilament proteins, and synaptophysin. |
1992-08-06 |
2023-08-11 |
human |
| N Spruston, D Johnsto. Perforated patch-clamp analysis of the passive membrane properties of three classes of hippocampal neurons. Journal of neurophysiology. vol 67. issue 3. 1992-06-10. PMID:1578242. |
changing the membrane potential by constant current injection resulted in changes in rn and tau 0; subthreshold depolarization produced an increase, and hyperpolarization a decrease, in both rn and tau 0 for all three classes of hippocampal neurons. |
1992-06-10 |
2023-08-11 |
Not clear |
| N Spruston, D Johnsto. Perforated patch-clamp analysis of the passive membrane properties of three classes of hippocampal neurons. Journal of neurophysiology. vol 67. issue 3. 1992-06-10. PMID:1578242. |
extracellular cs+ effectively blocked the sag in all three classes of hippocampal neurons, but the effect of cs+ on rn, tau 0, and the voltage dependence of these parameters was unique for each class of neurons. |
1992-06-10 |
2023-08-11 |
Not clear |
| Y Gache, J Guilleminot, F Ricolfi, G Theiss, J Nune. A tau-related protein of 130 kDa is present in Alzheimer brain. Journal of neurochemistry. vol 58. issue 6. 1992-06-04. PMID:1374115. |
two abnormal entities of 69 and 130 kda, immunologically related to the microtubule-associated tau proteins, are present in the hippocampus and the frontal cortex of the alzheimer brain, which contain a large number of neurofibrillary tangles (nfts), but are absent in the cerebellum, which does not contain these structures. |
1992-06-04 |
2023-08-11 |
Not clear |
| R W Shin, T Iwaki, T Kitamoto, Y Sato, J Tateish. Massive accumulation of modified tau and severe depletion of normal tau characterize the cerebral cortex and white matter of Alzheimer's disease. Demonstration using the hydrated autoclaving method. The American journal of pathology. vol 140. issue 4. 1992-05-11. PMID:1373272. |
using the hydrated autoclaving method, a new immunohistochemical procedure to enhance tau immunoreactivity in formalin-fixed brain tissue, the authors recently reported that tau protein is detected in neuronal cell bodies and proximal dendrites, gray matter neuropil, axons, and glial cells in normal human hippocampus and neocortex. |
1992-05-11 |
2023-08-11 |
human |
| G T Bramblett, J Q Trojanowski, V M Le. Regions with abundant neurofibrillary pathology in human brain exhibit a selective reduction in levels of binding-competent tau and accumulation of abnormal tau-isoforms (A68 proteins). Laboratory investigation; a journal of technical methods and pathology. vol 66. issue 2. 1992-03-09. PMID:1735956. |
to elucidate the events involved in this process, we compared the relative levels of binding-competent (bc) and binding-incompetent (bi) tau with the level of a68 in six different regions (hippocampus, fornix, frontal grey and white matter, and cerebellar grey and white matter) of fresh ad and control brains. |
1992-03-09 |
2023-08-11 |
human |
| G T Bramblett, J Q Trojanowski, V M Le. Regions with abundant neurofibrillary pathology in human brain exhibit a selective reduction in levels of binding-competent tau and accumulation of abnormal tau-isoforms (A68 proteins). Laboratory investigation; a journal of technical methods and pathology. vol 66. issue 2. 1992-03-09. PMID:1735956. |
we view the reductions in bc tau in fornix and frontal white matter to be a consequence of the reductions in their associated grey matter regions i.e., hippocampus and frontal grey matter. |
1992-03-09 |
2023-08-11 |
human |
| H Ito, S Goto, A Hirano, S H Ye. Immunohistochemical study of the hippocampus in parkinsonism-dementia complex on Guam. Journal of geriatric psychiatry and neurology. vol 4. issue 3. 1991-12-27. PMID:1953965. |
this investigation concerns the expression of paired helical filaments, tau protein, ubiquitin, beta-amyloid protein, and synaptophysin in the hippocampus of patients with parkinsonism-dementia complex on guam (pdc) and alzheimer's disease. |
1991-12-27 |
2023-08-11 |
Not clear |
| C Bancher, I Grundke-Iqbal, K Iqbal, V A Fried, H T Smith, H M Wisniewsk. Abnormal phosphorylation of tau precedes ubiquitination in neurofibrillary pathology of Alzheimer disease. Brain research. vol 539. issue 1. 1991-05-22. PMID:1849776. |
on tissue sections of alzheimer brain, 4 antibodies to tau immunolabel not only neurofibrillary tangles, neuritic plaques and neuropil threads but also the tangle-free cytoplasm of a subset of hippocampal and cortical neurons we believe to be at a stage of alteration preceding the formation of paired helical filaments (phf). |
1991-05-22 |
2023-08-11 |
Not clear |
| I Mody, D L Tanelian, M B MacIve. Halothane enhances tonic neuronal inhibition by elevating intracellular calcium. Brain research. vol 538. issue 2. 1991-05-16. PMID:1901506. |
using whole cell patch-clamp recording in hippocampal slices, halothane and pentobarbital were found to prolong the decay time constant (tau(d)) of gabaa-mediated spontaneous inhibitory postsynaptic currents (sipscs). |
1991-05-16 |
2023-08-11 |
Not clear |
| A J Barton, P J Harrison, A Najlerahim, J Heffernan, B McDonald, J R Robinson, D C Davies, W J Harrison, P Mitra, J A Hard. Increased tau messenger RNA in Alzheimer's disease hippocampus. The American journal of pathology. vol 137. issue 3. 1990-10-12. PMID:2119143. |
increased tau messenger rna in alzheimer's disease hippocampus. |
1990-10-12 |
2023-08-11 |
Not clear |
| A J Barton, P J Harrison, A Najlerahim, J Heffernan, B McDonald, J R Robinson, D C Davies, W J Harrison, P Mitra, J A Hard. Increased tau messenger RNA in Alzheimer's disease hippocampus. The American journal of pathology. vol 137. issue 3. 1990-10-12. PMID:2119143. |
we detected tau mrna using in situ hybridization histochemistry in the hippocampus, visual cortex, and cerebellum, and compared its level in alzheimer's disease with controls. |
1990-10-12 |
2023-08-11 |
Not clear |
| A J Barton, P J Harrison, A Najlerahim, J Heffernan, B McDonald, J R Robinson, D C Davies, W J Harrison, P Mitra, J A Hard. Increased tau messenger RNA in Alzheimer's disease hippocampus. The American journal of pathology. vol 137. issue 3. 1990-10-12. PMID:2119143. |
a significant and gene-specific increase in tau mrna hybridization was found in hippocampal fields ca4 and ca3, with a similar trend in the dentate gyrus. |
1990-10-12 |
2023-08-11 |
Not clear |