| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Oh, C G Jang, I K H. Activation of protein kinase C by phorbol dibutyrate potentiates [3H]MK-801 binding in rat brain slices. Brain research. vol 793. issue 1-2. 1999-03-29. PMID:9630713. |
the density of [3h]mk-801 binding was highest in hippocampus and high levels were found in cortex, striatum and thalamus. |
1999-03-29 |
2023-08-12 |
rat |
| K Kawabe, T Yoshihara, Y Ichitani, T Iwasak. Intrahippocampal D-cycloserine improves MK-801-induced memory deficits: radial-arm maze performance in rats. Brain research. vol 814. issue 1-2. 1999-03-16. PMID:9838131. |
in order to investigate whether strychnine-insensitive glycine sites coupled with hippocampal nmda (n-methyl-d-aspartate) receptors are involved in spatial memory in rats, we examined the effects of intrahippocampal treatment of d-cycloserine (dcs), a glycine-site agonist, on spatial-memory deficits which were produced by an nmda antagonist mk-801 (dizocilpine) on the radial-arm maze task. |
1999-03-16 |
2023-08-12 |
rat |
| E Fedele, G Varnier, M A Ansaldo, M Raiter. Nicotine administration stimulates the in vivo N-methyl-D-aspartate receptor/nitric oxide/cyclic GMP pathway in rat hippocampus through glutamate release. British journal of pharmacology. vol 125. issue 5. 1999-02-26. PMID:9846643. |
nicotine was able to stimulate cyclic gmp outflow also when administered directly into the hippocampus; the effect was sensitive to mecamylamine, l-noarg, odq or mk-801. |
1999-02-26 |
2023-08-12 |
rat |
| U Martens, B Capito, A Wre. Septotemporal distribution of [3H]MK-801, [3H]AMPA and [3H]Kainate binding sites in the rat hippocampus. Anatomy and embryology. vol 198. issue 3. 1998-12-09. PMID:9764974. |
septotemporal distribution of [3h]mk-801, [3h]ampa and [3h]kainate binding sites in the rat hippocampus. |
1998-12-09 |
2023-08-12 |
rat |
| C Arias, F Becerra-García, I Arrieta, R Tapi. The protein phosphatase inhibitor okadaic acid induces heat shock protein expression and neurodegeneration in rat hippocampus in vivo. Experimental neurology. vol 153. issue 2. 1998-11-25. PMID:9784284. |
the expression of the heat shock protein was partially prevented in the injected hippocampus and completely blocked in the contralateral ca1 region, by the systemic previous administration of the nmda receptor antagonist mk-801. |
1998-11-25 |
2023-08-12 |
rat |
| T Ma, H H Chen, D K Lim, A S Hume, I K H. Excitatory amino acids and lead-induced neurotoxicity. The Journal of toxicological sciences. vol 23 Suppl 2. 1998-11-17. PMID:9760459. |
however, lead caused a significant increase in [3h]mk-801 binding in the hippocampus including ca1 and ca2, and in the occipital and temporal cortical areas at pn 56 and at pn 112. |
1998-11-17 |
2023-08-12 |
rat |
| H S Mangat, A Islam, C Heigensköld, A Mustafa, B Winblad, A Ade. Long-term adrenalectomy decreases NMDA receptors in rat hippocampus. Neuroreport. vol 9. issue 9. 1998-09-25. PMID:9674584. |
hippocampal sections of control and adrenalectomized rats were incubated with [3h]mk-801, a radiolabeled non-competitive inhibitor of the nmda receptor. |
1998-09-25 |
2023-08-12 |
rat |
| E L Roberts, D Wisotzky, C P Chi. Aging and the effects of MK-801 on anoxic damage in rat hippocampal slices. Brain research. vol 791. issue 1-2. 1998-08-03. PMID:9593969. |
aging and the effects of mk-801 on anoxic damage in rat hippocampal slices. |
1998-08-03 |
2023-08-12 |
rat |
| E L Roberts, D Wisotzky, C P Chi. Aging and the effects of MK-801 on anoxic damage in rat hippocampal slices. Brain research. vol 791. issue 1-2. 1998-08-03. PMID:9593969. |
in both adult and aged hippocampal slices, nmda receptor blockade with mk-801 did not affect the onset of anoxic depolarization. |
1998-08-03 |
2023-08-12 |
rat |
| P Meoni, M Mugnaini, B H Bunnemann, D G Trist, N G Bower. [3H]MK-801 binding and the mRNA for the NMDAR1 subunit of the NMDA receptor are differentially distributed in human and rat forebrain. Brain research. Molecular brain research. vol 54. issue 1. 1998-06-10. PMID:9526033. |
the hippocampi of either species presented similar levels of [3h]mk-801 binding and nmdar1 mrna, but when the two signals were measured in specific subfields of the hippocampal formation, the differential distribution of the two signals reflected the anatomy of hippocampal connections assuming a preferential dendritic distribution for mk-801 binding. |
1998-06-10 |
2023-08-12 |
human |
| W Lasoń, J Turchan, B Przewłocka, D Labuz, H Machelska, R Przewłock. Effects of pentylenetetrazol kindling on glutamate receptor genes expression in the rat hippocampus. Brain research. vol 785. issue 2. 1998-05-29. PMID:9518693. |
a receptor autoradiography showed an increase in the [3h]mk-801 binding density in the hippocampus following both acute and repeated pentylenetetrazol administration. |
1998-05-29 |
2023-08-12 |
rat |
| K Morimoto, K Yoshimi, T Tonohiro, N Yamada, T Oda, I Kanek. Co-injection of beta-amyloid with ibotenic acid induces synergistic loss of rat hippocampal neurons. Neuroscience. vol 84. issue 2. 1998-05-22. PMID:9539218. |
dizocilpine maleate (mk-801), an antagonist for an excitatory amino acid receptor, completely inhibited the neuronal death in rat hippocampus. |
1998-05-22 |
2023-08-12 |
rat |
| Y Nomura, T Arima, T Namba, M Hattori, S Kadot. [Ameliorating effects of dan-shen and its major ingredient calcium/magnesium lithospermate B on cognitive deficiencies in senescence-accelerated mouse]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 110 Suppl 1. 1998-05-07. PMID:9503422. |
neurochemical investigations indicated that both drugs did not affect the cholinergic system, but enhanced functions of the glutamate-pkc system in hippocampus, since the increases in [3h]mk-801 ((+)-5-methyl-10,11-dihydro-5h-dibenzo[a,b]-cyclohepten-5,10-imine maleate) binding in cortex and [3h]pdbu (phorbol 12,13-dibutyrate) binding in hippocampus were observed in dme and lsb treatments. |
1998-05-07 |
2023-08-12 |
mouse |
| M T Su, W B Lin, W M Lue, C Y Cheng, P L Ta. Blockade of the development of morphine tolerance by U-50,488, an AVP antagonist or MK-801 in the rat hippocampal slice. British journal of pharmacology. vol 123. issue 4. 1998-04-16. PMID:9517380. |
blockade of the development of morphine tolerance by u-50,488, an avp antagonist or mk-801 in the rat hippocampal slice. |
1998-04-16 |
2023-08-12 |
rat |
| M T Su, W B Lin, W M Lue, C Y Cheng, P L Ta. Blockade of the development of morphine tolerance by U-50,488, an AVP antagonist or MK-801 in the rat hippocampal slice. British journal of pharmacology. vol 123. issue 4. 1998-04-16. PMID:9517380. |
in this study, we investigated the effects of different drugs (a kappa-opioid receptor agonist u-50,488, a vasopressin receptor antagonist dptyr(me)avp or an n-methyl-d-aspartate (nmda) receptor antagonist mk-801) on the development of morphine tolerance in rat hippocampal slices. |
1998-04-16 |
2023-08-12 |
rat |
| P Saransaari, S S Oj. Taurine release from the developing and ageing hippocampus: stimulation by agonists of ionotropic glutamate receptors. Mechanisms of ageing and development. vol 99. issue 3. 1998-03-25. PMID:9483494. |
the effect of kainate was blocked by 6-cyano-7-nitroquinoxaline-2,3-dione (cnqx) in the developing and aged hippocampus and those of ampa and nmda by 6-nitro-7-sulphamoylbenzo[f]quinoxaline-2,3-dione (nbqx) and dizocilpine a(mk-801) at every age studied. |
1998-03-25 |
2023-08-12 |
mouse |
| W Lasoń, J Turchan, B Przewłocka, D Labuz, R Przewłock. Effects of repeated MK-801 administration on the glutamate receptor gene expression in the rat hippocampus. Polish journal of pharmacology. vol 49. issue 4. 1998-03-02. PMID:9437768. |
effects of repeated mk-801 administration on the glutamate receptor gene expression in the rat hippocampus. |
1998-03-02 |
2023-08-12 |
rat |
| H N Bhargava, S Kumar, J T Bia. Up-regulation of brain N-methyl-D-aspartate receptors following multiple intracerebroventricular injections of [D-Pen2, D-Pen5] enkephalin and [D-Ala2, Glu4]deltorphin II in mice. Peptides. vol 18. issue 10. 1998-02-18. PMID:9437723. |
the binding of [3h]mk-801 was determined in brain regions (cortex, midbrain, pons and medulla, hippocampus, striatum, hypothalamus and amygdala). |
1998-02-18 |
2023-08-12 |
mouse |
| H N Bhargava, S Kumar, J T Bia. Up-regulation of brain N-methyl-D-aspartate receptors following multiple intracerebroventricular injections of [D-Pen2, D-Pen5] enkephalin and [D-Ala2, Glu4]deltorphin II in mice. Peptides. vol 18. issue 10. 1998-02-18. PMID:9437723. |
at 5 nm-concentration, the binding of [3h]mk-801 was increased in cerebral cortex, hippocampus, and pons and medulla of [d-pen2, d-pen5]enkephalin treated mice. |
1998-02-18 |
2023-08-12 |
mouse |
| H N Bhargava, S Kumar, J T Bia. Up-regulation of brain N-methyl-D-aspartate receptors following multiple intracerebroventricular injections of [D-Pen2, D-Pen5] enkephalin and [D-Ala2, Glu4]deltorphin II in mice. Peptides. vol 18. issue 10. 1998-02-18. PMID:9437723. |
in [d-ala2, glu4]deltorphin ii treated mice, the binding of [3h]mk-801 was increased in cerebral cortex and hippocampus. |
1998-02-18 |
2023-08-12 |
mouse |