| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J G Rudolph, D W Walker, Y Iimuro, R G Thurman, F T Crew. NMDA receptor binding in adult rat brain after several chronic ethanol treatment protocols. Alcoholism, clinical and experimental research. vol 21. issue 8. 1998-01-16. PMID:9394125. |
(hepatology 5:224-232, 1985), small, but significant, increases in the binding of [3h]mk-801 were seen in the ca1 and dentate gyrus regions of the hippocampus. |
1998-01-16 |
2023-08-12 |
rat |
| E Gilland, E Bona, M Levene, H Hagber. Magnesium and the N-methyl-D-aspartate receptor antagonist dizocilpine maleate neither increase glucose use nor induce a 72-kilodalton heat shock protein expression in the immature rat brain. Pediatric research. vol 42. issue 4. 1997-11-12. PMID:9380438. |
both doses of mk-801 and 4 mmol/kg mgso4 induced a temporary decrease in glucose use in the posterior cingulate and retrosplenial cortex, the ca1 and ca3 subfields of the hippocampus, the caudoputamen, and the parietal cortex. |
1997-11-12 |
2023-08-12 |
rat |
| J K Robinson, J B Ma. Differential effects on delayed non-matching-to-position in rats of microinjections of muscarinic receptor antagonist scopolamine or NMDA receptor antagonist MK-801 into the dorsal or ventral extent of the hippocampus. Brain research. vol 765. issue 1. 1997-11-06. PMID:9310393. |
differential effects on delayed non-matching-to-position in rats of microinjections of muscarinic receptor antagonist scopolamine or nmda receptor antagonist mk-801 into the dorsal or ventral extent of the hippocampus. |
1997-11-06 |
2023-08-12 |
rat |
| J K Robinson, J B Ma. Differential effects on delayed non-matching-to-position in rats of microinjections of muscarinic receptor antagonist scopolamine or NMDA receptor antagonist MK-801 into the dorsal or ventral extent of the hippocampus. Brain research. vol 765. issue 1. 1997-11-06. PMID:9310393. |
mk-801 administered into dorsal hippocampus produced delay-independent deficits in dnmtp delayed choice. |
1997-11-06 |
2023-08-12 |
rat |
| J K Robinson, J B Ma. Differential effects on delayed non-matching-to-position in rats of microinjections of muscarinic receptor antagonist scopolamine or NMDA receptor antagonist MK-801 into the dorsal or ventral extent of the hippocampus. Brain research. vol 765. issue 1. 1997-11-06. PMID:9310393. |
neither scopolamine administered into the dorsal or ventral hippocampus, nor mk-801 administered into the ventral hippocampus, produced significant disruption of dnmtp delayed choice. |
1997-11-06 |
2023-08-12 |
rat |
| J K Robinson, J B Ma. Differential effects on delayed non-matching-to-position in rats of microinjections of muscarinic receptor antagonist scopolamine or NMDA receptor antagonist MK-801 into the dorsal or ventral extent of the hippocampus. Brain research. vol 765. issue 1. 1997-11-06. PMID:9310393. |
scopolamine into the dorsal and ventral hippocampus increased errors of omission, scopolamine into the ventral hippocampus decreased sample response accuracy, and mk-801 into the dorsal hippocampus decreased sample response accuracy and increased response bias. |
1997-11-06 |
2023-08-12 |
rat |
| T Ma, H H Chen, D K Lim, A S Hume, I K H. Effects of subacute lead exposure on [3H]MK-801 binding in hippocampus and cerebral cortex in the adult rat. Brain research. vol 760. issue 1-2. 1997-10-28. PMID:9237534. |
effects of subacute lead exposure on [3h]mk-801 binding in hippocampus and cerebral cortex in the adult rat. |
1997-10-28 |
2023-08-12 |
rat |
| J L Diaz-Granados, K Spuhler-Phillips, M W Lilliquist, A Amsel, S W Lesli. Effects of prenatal and early postnatal ethanol exposure on [3H]MK-801 binding in rat cortex and hippocampus. Alcoholism, clinical and experimental research. vol 21. issue 5. 1997-10-23. PMID:9267538. |
effects of prenatal and early postnatal ethanol exposure on [3h]mk-801 binding in rat cortex and hippocampus. |
1997-10-23 |
2023-08-12 |
rat |
| I Smolders, G M Khan, J Manil, G Ebinger, Y Michott. NMDA receptor-mediated pilocarpine-induced seizures: characterization in freely moving rats by microdialysis. British journal of pharmacology. vol 121. issue 6. 1997-10-08. PMID:9249254. |
intrahippocampal administration of mk-801 and lamotrigine resulted in an elevation of hippocampal dopamine levels and protected the rats from the pilocarpine-induced seizures. |
1997-10-08 |
2023-08-12 |
human |
| I Smolders, G M Khan, J Manil, G Ebinger, Y Michott. NMDA receptor-mediated pilocarpine-induced seizures: characterization in freely moving rats by microdialysis. British journal of pharmacology. vol 121. issue 6. 1997-10-08. PMID:9249254. |
hippocampal dopamine release may be functionally important in epileptogenesis and may participate in the anticonvulsant effects of mk-801 and lamotrigine. |
1997-10-08 |
2023-08-12 |
human |
| H Katoh, K Sima, H Nawashiro, K Wada, H Chigasak. The effect of MK-801 on extracellular neuroactive amino acids in hippocampus after closed head injury followed by hypoxia in rats. Brain research. vol 758. issue 1-2. 1997-09-16. PMID:9203544. |
the effect of mk-801 on extracellular neuroactive amino acids in hippocampus after closed head injury followed by hypoxia in rats. |
1997-09-16 |
2023-08-12 |
rat |
| S E Tan, S S Che. The activation of calcium/calmodulin-dependent protein kinase II after glutamate or potassium stimulation in hippocampal slices. Brain research bulletin. vol 43. issue 3. 1997-09-16. PMID:9227836. |
rat hippocampal slices were preincubated with one of the drugs (egta, dl-apv, cnqx, ap3, nitrendipine, kn-62, staurosporin, and h-89) before they were stimulated with either glutamate/glycine (100 microm/1 microm) or kcl (60 mm). |
1997-09-16 |
2023-08-12 |
rat |
| R S Bitner, G K Yim, G E Iso. 2-Iminothiazolidine-4-carboxylic acid produces hippocampal CA1 lesions independent of seizure excitation and glutamate receptor activation. Neurotoxicology. vol 18. issue 1. 1997-09-09. PMID:9216001. |
neither mk-801 (dizocilpine maleate) nor cnqx (6-cyano-7-nitroquinoxaline-2,3-dione) pretreatment prevented hippocampal lesions produced by 2-ica. |
1997-09-09 |
2023-08-12 |
mouse |
| R S Bitner, G K Yim, G E Iso. 2-Iminothiazolidine-4-carboxylic acid produces hippocampal CA1 lesions independent of seizure excitation and glutamate receptor activation. Neurotoxicology. vol 18. issue 1. 1997-09-09. PMID:9216001. |
in contrast, mk-801 significantly reduced the frequency of mice displaying glutamate hippocampal lesions, but failed to block seizures produced by glutamate. |
1997-09-09 |
2023-08-12 |
mouse |
| H Ishimaru, A Takahashi, Y Ikarashi, Y Maruyam. Effects of MK-801 and pentobarbital on cholinergic terminal damage and delayed neuronal death in the ischemic gerbil hippocampus. Brain research bulletin. vol 43. issue 1. 1997-09-04. PMID:9205799. |
effects of mk-801 and pentobarbital on cholinergic terminal damage and delayed neuronal death in the ischemic gerbil hippocampus. |
1997-09-04 |
2023-08-12 |
Not clear |
| H Kato, T Araki, T Chen, X H Liu, T Hiranuma, K Murase, Y Itoyama, K Kogur. Effects of chronic treatment with a cyclic AMP-selective phosphodiesterase inhibitor, rolipram, on excitatory amino acid neurotransmission systems in young and aged rat brains. Journal of neural transmission (Vienna, Austria : 1996). vol 104. issue 2-3. 1997-09-03. PMID:9203088. |
the highest binding of [3h]mk-801, [3h]glycine, and d-[3h]aspartate was seen in the hippocampus in vehicle-treated rats. |
1997-09-03 |
2023-08-12 |
rat |
| M Toropainen, R Näkki, A Honkanen, P H Rosenberg, D J Laurie, M Pelto-Huikko, J Koistinaho, C J Eriksson, E R Korp. Behavioral sensitivity and ethanol potentiation of the N-methyl-D-aspartate receptor antagonist MK-801 in a rat line selected for high ethanol sensitivity. Alcoholism, clinical and experimental research. vol 21. issue 4. 1997-08-20. PMID:9194922. |
ethanol treatment decreased the cerebellar and hippocampal cgmp concentrations both with and without mk-801 pretreatment in both rat lines. |
1997-08-20 |
2023-08-12 |
rat |
| T Ma, H H Chen, H L Chang, A S Hume, I K H. Effects of chronic lead exposure on [3H]MK-801 binding in the brain of rat. Toxicology letters. vol 92. issue 1. 1997-08-20. PMID:9242358. |
however, lead caused a significant increase in [3h]mk-801 binding in the hippocampus including ca1 and ca2, and in the occipital and temporal cortical areas at pn 56 and at pn 112. |
1997-08-20 |
2023-08-12 |
rat |
| S Tanaka, Y Kiuchi, S Numazawa, K Oguchi, T Yoshida, Y Kuroiw. Changes in glutamate receptors, c-fos mRNA expression and activator protein-1 (AP-1) DNA binding activity in the brain of phenobarbital-dependent and -withdrawn rats. Brain research. vol 756. issue 1-2. 1997-08-15. PMID:9187311. |
however, [3h]mk-801 binding in the hippocampus and [3h]6-cyano-7-nitroquinoxaline-2,3-dione (cnqx) and [3h]kainic acid binding in the hippocampus and cerebral cortex were essentially unchanged in both groups. |
1997-08-15 |
2023-08-12 |
rat |
| K Wedzony, M Maćkowiak, A Czyrak, K Fijał, B Michalsk. Single doses of MK-801, a non-competitive antagonist of NMDA receptors, increase the number of 5-HT1A serotonin receptors in the rat brain. Brain research. vol 756. issue 1-2. 1997-08-15. PMID:9187317. |
the binding of [3h]8-oh-dpat to 5-ht1a serotonin receptors was increased after mk-801 (0.4 mg/kg) as was shown by autoradiographic studies in the frontal, cingulate and part of enthorinal cortex, subregions of the hippocampus and raphe nuclei. |
1997-08-15 |
2023-08-12 |
rat |