All Relations between (2R)-amino-5-phosphonovaleric acid (AP5) and hippocampus

Publication Sentence Publish Date Extraction Date Species
Alessandro Piva, Lucia Caffino, Francesca Mottarlini, Nicholas Pintori, Fernando Castillo Díaz, Fabio Fumagalli, Cristiano Chiamuler. Metaplastic Effects of Ketamine and MK-801 on Glutamate Receptors Expression in Rat Medial Prefrontal Cortex and Hippocampus. Molecular neurobiology. vol 58. issue 7. 2021-11-03. PMID:33723767. metaplastic effects of ketamine and mk-801 on glutamate receptors expression in rat medial prefrontal cortex and hippocampus. 2021-11-03 2023-08-13 rat
Alessandro Piva, Lucia Caffino, Francesca Mottarlini, Nicholas Pintori, Fernando Castillo Díaz, Fabio Fumagalli, Cristiano Chiamuler. Metaplastic Effects of Ketamine and MK-801 on Glutamate Receptors Expression in Rat Medial Prefrontal Cortex and Hippocampus. Molecular neurobiology. vol 58. issue 7. 2021-11-03. PMID:33723767. the aim of the present study was to investigate the molecular changes occurring at glutamatergic synapses 24 h after ketamine or mk-801 treatment in the rat medial prefrontal cortex (mpfc) and hippocampus (hipp). 2021-11-03 2023-08-13 rat
Alessandro Piva, Lucia Caffino, Francesca Mottarlini, Nicholas Pintori, Fernando Castillo Díaz, Fabio Fumagalli, Cristiano Chiamuler. Metaplastic Effects of Ketamine and MK-801 on Glutamate Receptors Expression in Rat Medial Prefrontal Cortex and Hippocampus. Molecular neurobiology. vol 58. issue 7. 2021-11-03. PMID:33723767. taken together, these findings indicate a fine tuning of glutamatergic synapses by ketamine compared to mk-801 both in the mpfc and hipp. 2021-11-03 2023-08-13 rat
Giuliana S Zuccoli, Guilherme Reis-de-Oliveira, Bruna Garbes, Peter Falkai, Andrea Schmitt, Helder I Nakaya, Daniel Martins-de-Souz. Linking proteomic alterations in schizophrenia hippocampus to NMDAr hypofunction in human neurons and oligodendrocytes. European archives of psychiatry and clinical neuroscience. vol 271. issue 8. 2021-11-03. PMID:33751207. here, we performed proteomic analysis of hippocampus postmortem samples from schizophrenia patients as well as neural cells-neurons and oligodendrocytes-treated with mk-801, an nmda receptor antagonist. 2021-11-03 2023-08-13 human
Ivan Goussakov, Sylvia Synowiec, Daniil P Aksenov, Alexander Drobyshevsk. Occlusion of activity dependent synaptic plasticity by late hypoxic long term potentiation after neonatal intermittent hypoxia. Experimental neurology. vol 337. 2021-09-13. PMID:33358869. in vivo recordings of schaffer collateral stimulation-induced synaptic responses during and after ih in the ca1 region of the hippocampus revealed pathological late phase hypoxic long term potentiation (hltp) (154%) that lasted more than four hours and could be reversed by depotentiation with low frequency stimulation (lfs), or abolished by nmda and pka inhibitors (mk-801 and cmiq). 2021-09-13 2023-08-13 mouse
Hao Zhu, Yu Yang, Min Zhu, Xiao Shi, Le Ye, Song Zhang, Hongwei Fang, Wenjuan Y. Alteration in the expression of inflammatory cytokines in primary hippocampal astrocytes in response to MK-801 through ERK1/2 and PI3K signals. Cytokine. vol 138. 2021-07-26. PMID:33187817. alteration in the expression of inflammatory cytokines in primary hippocampal astrocytes in response to mk-801 through erk1/2 and pi3k signals. 2021-07-26 2023-08-13 rat
Hao Zhu, Yu Yang, Min Zhu, Xiao Shi, Le Ye, Song Zhang, Hongwei Fang, Wenjuan Y. Alteration in the expression of inflammatory cytokines in primary hippocampal astrocytes in response to MK-801 through ERK1/2 and PI3K signals. Cytokine. vol 138. 2021-07-26. PMID:33187817. our previous study showed that dizocilpine (mk-801) induced schizophrenia-like behavior in rats, enhanced gfap expression, and activated primary cultured hippocampal astrocytes. 2021-07-26 2023-08-13 rat
Hao Zhu, Yu Yang, Min Zhu, Xiao Shi, Le Ye, Song Zhang, Hongwei Fang, Wenjuan Y. Alteration in the expression of inflammatory cytokines in primary hippocampal astrocytes in response to MK-801 through ERK1/2 and PI3K signals. Cytokine. vol 138. 2021-07-26. PMID:33187817. to address this issue, il1β, il6, tnfα and il10 expression and secretion levels were evaluated in hippocampal astrocytes in response to mk-801 for 24 h by elisa and real-time pcr, with and without pretreatment of either the erk1/2 inhibitor, pd98059 or the pi3k inhibitor, ly294002. 2021-07-26 2023-08-13 rat
Hao Zhu, Yu Yang, Min Zhu, Xiao Shi, Le Ye, Song Zhang, Hongwei Fang, Wenjuan Y. Alteration in the expression of inflammatory cytokines in primary hippocampal astrocytes in response to MK-801 through ERK1/2 and PI3K signals. Cytokine. vol 138. 2021-07-26. PMID:33187817. mk-801 treatment did not induce hippocampal astrocytes apoptosis or proliferation, however, mk-801 enhanced astrocytes viability. 2021-07-26 2023-08-13 rat
Ayse Cigel, Oya Sayin, Seren Gulsen Gurgen, Atac Sonme. Long term neuroprotective effects of acute single dose MK-801treatment against traumatic brain injury in immature rats. Neuropeptides. vol 88. 2021-07-12. PMID:34098454. the study aims to investigate the long-term effects of mk-801 (dizocilpine), an n-methyl d-aspartate (nmda) receptor antagonist, on hippocampal damage, locomotor activity, and cognitive functions following tbi in immature rats. 2021-07-12 2023-08-13 rat
Ayse Cigel, Oya Sayin, Seren Gulsen Gurgen, Atac Sonme. Long term neuroprotective effects of acute single dose MK-801treatment against traumatic brain injury in immature rats. Neuropeptides. vol 88. 2021-07-12. PMID:34098454. histopathological and immunohistochemical evaluations showed that treatment with mk-801 significantly ameliorated the trauma-induced hippocampal neuron loss and increased bdnf, ngf, nmda-r, gfap expressions in ca1, ca3, and dg hippocampal regions. 2021-07-12 2023-08-13 rat
Ayse Cigel, Oya Sayin, Seren Gulsen Gurgen, Atac Sonme. Long term neuroprotective effects of acute single dose MK-801treatment against traumatic brain injury in immature rats. Neuropeptides. vol 88. 2021-07-12. PMID:34098454. these results show that acute treatment of mk-801 has a neuroprotective role against trauma-induced hippocampal neuron loss and associated cognitive impairment in rats. 2021-07-12 2023-08-13 rat
Maria E Plataki, Konstantinos Diskos, Christos Sougklakos, Marouso Velissariou, Alexandros Georgilis, Vasiliki Stavroulaki, Kyriaki Sidiropoulo. Effect of Neonatal Treatment With the NMDA Receptor Antagonist, MK-801, During Different Temporal Windows of Postnatal Period in Adult Prefrontal Cortical and Hippocampal Function. Frontiers in behavioral neuroscience. vol 15. 2021-06-29. PMID:34177484. effect of neonatal treatment with the nmda receptor antagonist, mk-801, during different temporal windows of postnatal period in adult prefrontal cortical and hippocampal function. 2021-06-29 2023-08-13 mouse
Wenjuan Yu, Hongwei Fang, Lei Zhang, Miaowen Hu, Sidi He, Huafang Li, Hao Zh. Reversible Changes in BDNF Expression in MK-801-Induced Hippocampal Astrocytes Through NMDAR/PI3K/ERK Signaling. Frontiers in cellular neuroscience. vol 15. 2021-06-01. PMID:34054433. we previously found that bdnf signaling was upregulated by mk-801 in cultured hippocampal astrocytes, but the underlying mechanism is not clear. 2021-06-01 2023-08-13 rat
Wenjuan Yu, Hongwei Fang, Lei Zhang, Miaowen Hu, Sidi He, Huafang Li, Hao Zh. Reversible Changes in BDNF Expression in MK-801-Induced Hippocampal Astrocytes Through NMDAR/PI3K/ERK Signaling. Frontiers in cellular neuroscience. vol 15. 2021-06-01. PMID:34054433. to address this issue, the levels of bdnf expression and secretion were evaluated in hippocampal astrocytes incubated with mk-801 by elisa and qpcr, with and without nmda co-incubation or pretreatment of either the erk1/2 inhibitor, pd98059 or the pi3k inhibitor, ly294002. 2021-06-01 2023-08-13 rat
Wenjuan Yu, Hongwei Fang, Lei Zhang, Miaowen Hu, Sidi He, Huafang Li, Hao Zh. Reversible Changes in BDNF Expression in MK-801-Induced Hippocampal Astrocytes Through NMDAR/PI3K/ERK Signaling. Frontiers in cellular neuroscience. vol 15. 2021-06-01. PMID:34054433. in the current study, we demonstrate that mk-801 treatment (20 μm for 5 days) enhances the proliferation of rat cultured hippocampal astrocytes. 2021-06-01 2023-08-13 rat
Carey Wilson, Shanshan Li, Anthony J Hannan, Thibault Renoi. Antidepressant-like effects of ketamine in a mouse model of serotonergic dysfunction. Neuropharmacology. vol 168. 2021-05-27. PMID:32061666. 5-htt ko mice also exhibited a reduced locomotor response to both mk-801 (another nmdar antagonist) and ketamine, and reduced glun2a protein levels in the hippocampus, suggesting glutamatergic dysfunction in this model. 2021-05-27 2023-08-13 mouse
Ming-Heng Hsiung, Wan-Ling Huang, Li-Yu Kan, Li-Hsien Chen, Sherry Shu-Jung H. The facilitating effect of MK-801 on inhibitory avoidance memory via mTOR signaling in the mouse hippocampus. Behavioural brain research. vol 389. 2021-05-06. PMID:32348869. the facilitating effect of mk-801 on inhibitory avoidance memory via mtor signaling in the mouse hippocampus. 2021-05-06 2023-08-13 mouse
Ming-Heng Hsiung, Wan-Ling Huang, Li-Yu Kan, Li-Hsien Chen, Sherry Shu-Jung H. The facilitating effect of MK-801 on inhibitory avoidance memory via mTOR signaling in the mouse hippocampus. Behavioural brain research. vol 389. 2021-05-06. PMID:32348869. in this study, we investigated the effect of mk-801 on multiple memory stages of the inhibitory avoidance task, as well as its underlying signaling mechanism in the mouse hippocampus. 2021-05-06 2023-08-13 mouse
Ming-Heng Hsiung, Wan-Ling Huang, Li-Yu Kan, Li-Hsien Chen, Sherry Shu-Jung H. The facilitating effect of MK-801 on inhibitory avoidance memory via mTOR signaling in the mouse hippocampus. Behavioural brain research. vol 389. 2021-05-06. PMID:32348869. we next showed that mk-801 induced a fast-onset increase in the extent of mammalian target of rapamycin (mtor) phosphorylation in the hippocampus. 2021-05-06 2023-08-13 mouse