| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kiyoshi Asada, Yashige Kotake, Rumiko Asada, Deborah Saunders, Robert H Broyles, Rheal A Towner, Hiroshi Fukui, Robert A Floy. LINE-1 hypomethylation in a choline-deficiency-induced liver cancer in rats: dependence on feeding period. Journal of biomedicine & biotechnology. vol 2006. issue 1. 2010-06-09. PMID:16877811. |
chronic feeding of methyl-donor (methionine, choline, folic acid, and vitamin b12) deficient diet induces hepatocellular carcinoma formation in rats. |
2010-06-09 |
2023-08-12 |
rat |
| J H JONE. Effect of feeding succinylsulfathiazole to rats on a diet low in choline. Federation proceedings. vol 6. issue 1. 2010-03-29. PMID:20249656. |
effect of feeding succinylsulfathiazole to rats on a diet low in choline. |
2010-03-29 |
2023-08-12 |
rat |
| M Ardalan, K Rezayazdi, M Dehghan-Banadak. Investigation on the effect of supplementing rumen-protected forms of methionine and choline on health situation and reproductive performance of Holstein dairy cows. Pakistan journal of biological sciences : PJBS. vol 12. issue 1. 2009-07-23. PMID:19579921. |
the aim was to investigate the effect of feeding different levels of ruminally protected methionine and choline on health situation and reproductive indices of holstein dairy cows. |
2009-07-23 |
2023-08-12 |
Not clear |
| Minoru Setoue, Seiya Ohuchi, Tatsuya Morita, Kimio Sugiyam. Choline deprivation induces hyperhomocysteinemia in rats fed low methionine diets. Journal of nutritional science and vitaminology. vol 54. issue 6. 2009-04-15. PMID:19155587. |
feeding rats with the choline-deprived 25s diet for 10 d significantly increased plasma total homocysteine concentration to a level 2.68-times higher than that of the control group, whereas choline deprivation had no effect in rats fed the 25c diet. |
2009-04-15 |
2023-08-12 |
rat |
| Alexandre Ivanov, Susan Nash-Barboza, Sabrina Hinkis, Marie A Caudil. Genetic variants in phosphatidylethanolamine N-methyltransferase and methylenetetrahydrofolate dehydrogenase influence biomarkers of choline metabolism when folate intake is restricted. Journal of the American Dietetic Association. vol 109. issue 2. 2009-03-16. PMID:19167960. |
this controlled feeding study, conducted in 2000-2001, examined the effects of the pemt and mthfd1 genetic variants on biomarkers of choline metabolism in premenopausal mexican-american women (n=43) after a 7-week period of folate restriction (135 microg as dietary folate equivalents) and after a 7-week period of folate treatment (400 and 800 microg dietary folate equivalents/day combined). |
2009-03-16 |
2023-08-12 |
Not clear |
| Harold L Newmark, Kan Yang, Naoto Kurihara, Kunhua Fan, Leonard H Augenlicht, Martin Lipki. Western-style diet-induced colonic tumors and their modulation by calcium and vitamin D in C57Bl/6 mice: a preclinical model for human sporadic colon cancer. Carcinogenesis. vol 30. issue 1. 2009-02-12. PMID:19017685. |
we also similarly tested individual supplements of methyl donor (transfer) nutrients (folic acid, choline, methionine and dietary fiber), but these had no significant effect on colonic tumor incidence or multiplicity, whereas supplementation with combined calcium and vitamin d produced significant decrease in both colon tumor incidence and multiplicity, during 2 years of feeding. |
2009-02-12 |
2023-08-12 |
mouse |
| Christian M Abratte, Wei Wang, Rui Li, Juan Axume, David J Moriarty, Marie A Caudil. Choline status is not a reliable indicator of moderate changes in dietary choline consumption in premenopausal women. The Journal of nutritional biochemistry. vol 20. issue 1. 2009-01-07. PMID:18495456. |
as an extension of our previous work, this 14-week controlled feeding study investigated the relationship between moderate changes in dietary choline intake and blood indicators of status. |
2009-01-07 |
2023-08-12 |
Not clear |
| Kun-Tai Li, Dong-Hong Liu, Ju Chu, Yong-Hong Wang, Ying-Ping Zhuang, Si-Liang Zhan. An effective and simplified pH-stat control strategy for the industrial fermentation of vitamin B(12) by Pseudomonas denitrificans. Bioprocess and biosystems engineering. vol 31. issue 6. 2008-11-13. PMID:18320234. |
results obtained from shake flask experiments showed that the feeding of carbon source (beet molasses or glucose) and methyl-group donor (betaine or choline chloride) significantly influenced the ph and the biosynthesis of vitamin b(12). |
2008-11-13 |
2023-08-12 |
Not clear |
| Charis Liapi, Irini Feskou, Apostolos Zarros, Haris Carageorgiou, Panagiota Galanopoulou, Stylianos Tsakiri. Equilibrated diet restores the effects of early age choline-deficient feeding on rat brain antioxidant status and enzyme activities: the role of homocysteine, L-phenylalanine and L-alanine. Metabolic brain disease. vol 23. issue 3. 2008-10-31. PMID:18642068. |
the aim of this study was to: (a)examine the effects of early age choline deficient diet (cdd) administration on the total antioxidant status (tas) and the activities of acetylcholinesterase (ache), (na(+),k(+))-atpase and mg(2+)-atpase in the rat brain, (b)investigate the effect of feeding restoration into an equilibrated diet on the above parameters, and (c)study the role of homocysteine (hcy), l: -phenylalanine (phe) and l: -alanine (ala) in certain of the above effects. |
2008-10-31 |
2023-08-12 |
rat |
| Wei-Na Cong, Rong-Ya Tao, Jin-Ying Tian, Geng-Tao Liu, Fei Y. The establishment of a novel non-alcoholic steatohepatitis model accompanied with obesity and insulin resistance in mice. Life sciences. vol 82. issue 19-20. 2008-07-10. PMID:18417155. |
the novel model was induced in c57bl/6 mice by 23 weeks of ad libitum feeding of a modified high-fat diet (mhfd), with lower methinione and choline and higher fat content. |
2008-07-10 |
2023-08-12 |
mouse |
| L M MORRISON, A ROSS. Absorption of aortic atherosclerosis by choline feeding. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). vol 69. issue 2. 2007-12-27. PMID:18102203. |
absorption of aortic atherosclerosis by choline feeding. |
2007-12-27 |
2023-08-12 |
Not clear |
| Jun Yu, Eagle S H Chu, Alex Y Hui, Kin F Cheung, Henry L Y Chan, Wai K Leung, Geoffrey C Farrell, Joseph J Y Sun. Lipoprotein lipase activator ameliorates the severity of dietary steatohepatitis. Biochemical and biophysical research communications. vol 356. issue 1. 2007-06-20. PMID:17350593. |
dietary model of steatohepatitis was established by feeding mice a methionine choline deficient (mcd) diet. |
2007-06-20 |
2023-08-12 |
mouse |
| Zhaoyu Li, Luis B Agellon, Dennis E Vanc. Choline redistribution during adaptation to choline deprivation. The Journal of biological chemistry. vol 282. issue 14. 2007-06-06. PMID:17283071. |
complete choline deprivation is achieved by feeding pemt(-)(/)(-) mice a choline-deficient diet and is lethal due to liver failure. |
2007-06-06 |
2023-08-12 |
mouse |
| Peter J Raubenheimer, Moffat J Nyirenda, Brian R Walke. A choline-deficient diet exacerbates fatty liver but attenuates insulin resistance and glucose intolerance in mice fed a high-fat diet. Diabetes. vol 55. issue 7. 2006-08-14. PMID:16804070. |
in choline replete animals, high-fat feeding induced weight gain, elevated liver triglycerides (171%), hyperinsulinemia, and glucose intolerance. |
2006-08-14 |
2023-08-12 |
mouse |
| D Zhou, K Ghebremeskel, M A Crawford, R Reife. Vitamin A deficiency enhances docosahexaenoic and osbond acids in liver of rats fed an alpha linolenic acid-adequate diet. Lipids. vol 41. issue 3. 2006-06-30. PMID:16711595. |
after 7 wk of feeding, liver and colon choline (cpg) and ethanolamine (epg) phosphoglyceride fa were analyzed. |
2006-06-30 |
2023-08-12 |
rat |
| Zhaoyu Li, Luis B Agellon, Dennis E Vanc. Phosphatidylcholine homeostasis and liver failure. The Journal of biological chemistry. vol 280. issue 45. 2006-01-12. PMID:16144842. |
complete choline deprivation in mice by feeding pemt(-/-) mice a choline-deficient (cd) diet decreases hepatic pc by 50% and is lethal within 5 days. |
2006-01-12 |
2023-08-12 |
mouse |
| Leslie M Fischer, Julie A Scearce, Mei-Heng Mar, Jayanti R Patel, Renee T Blanchard, Beth A Macintosh, Marjorie G Busby, Steven H Zeise. Ad libitum choline intake in healthy individuals meets or exceeds the proposed adequate intake level. The Journal of nutrition. vol 135. issue 4. 2005-05-31. PMID:15795442. |
choline intakes estimated from the 3-d food records were significantly lower than this (when expressed as mg/kg, or as total mg, but not when normalized to energy intake), suggesting underreporting of food intake. |
2005-05-31 |
2023-08-12 |
human |
| Sean W P Koppe, Atul Sahai, Padmini Malladi, Peter F Whitington, Richard M Gree. Pentoxifylline attenuates steatohepatitis induced by the methionine choline deficient diet. Journal of hepatology. vol 41. issue 4. 2005-03-03. PMID:15464239. |
feeding mice a methionine choline deficient (mcd) diet serves as a nutritional model of non-alcoholic steatohepatitis (nash). |
2005-03-03 |
2023-08-12 |
mouse |
| C H BEST, W S HARTROF. Liver damage produced by feeding alcohol or sugar and its prevention by choline. British medical journal. vol 2. issue 4635. 2004-09-30. PMID:15393035. |
liver damage produced by feeding alcohol or sugar and its prevention by choline. |
2004-09-30 |
2023-08-12 |
Not clear |
| Atul Sahai, Padmini Malladi, Hector Melin-Aldana, Richard M Green, Peter F Whitingto. Upregulation of osteopontin expression is involved in the development of nonalcoholic steatohepatitis in a dietary murine model. American journal of physiology. Gastrointestinal and liver physiology. vol 287. issue 1. 2004-07-23. PMID:15044174. |
feeding mice a diet deficient in methionine and choline (mcd diet) induces experimental nash. |
2004-07-23 |
2023-08-12 |
mouse |