| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| I C PLOUGH, A J PATEK, M BEVAN. The relative effects of protein, choline, and methionine in the treatment of experimental dietary cirrhosis in the rat. The Journal of experimental medicine. vol 96. issue 3. 2004-02-15. PMID:14955576. |
these studies suggest that the feeding of high protein (30 per cent casein) diets to rats with nutritional cirrhosis produces reparative effects greater than those attributable to the supplements choline and methionine. |
2004-02-15 |
2023-08-12 |
rat |
| Emilia Ip, Geoffrey C Farrell, Graham Robertson, Pauline Hall, Richard Kirsch, Isabelle Leclerc. Central role of PPARalpha-dependent hepatic lipid turnover in dietary steatohepatitis in mice. Hepatology (Baltimore, Md.). vol 38. issue 1. 2003-07-25. PMID:12829994. |
we tested the hypothesis that increasing cyp4a through activation of peroxisome proliferator-activated receptor alpha (pparalpha) should aggravate steatohepatitis produced by feeding a methionine and choline deficient (mcd) diet. |
2003-07-25 |
2023-08-12 |
mouse |
| Susan J Hemmings, Judee Stricklan. Administration of diethylnitrosamine in the immediate postnatal period coupled with exposure to a choline deficient diet accelerates hepatocarcinogenesis in the rat. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 12. issue 5-6. 2003-06-10. PMID:12438770. |
subsequent feeding of a choline deficient diet could accelerate hepatic premalignancy in the rat. |
2003-06-10 |
2023-08-12 |
rat |
| G F BUCKLEY, W S HARTROF. Effects of choline on cardiovascular lesions induced by feeding large doses of vitamin D. The American journal of clinical nutrition. vol 2. issue 6. 2003-05-01. PMID:13207035. |
effects of choline on cardiovascular lesions induced by feeding large doses of vitamin d. |
2003-05-01 |
2023-08-12 |
Not clear |
| Songtao Yu, Kimihiko Matsusue, Papreddy Kashireddy, Wen-Qing Cao, Vaishalee Yeldandi, Anjana V Yeldandi, M Sambasiva Rao, Frank J Gonzalez, Janardan K Redd. Adipocyte-specific gene expression and adipogenic steatosis in the mouse liver due to peroxisome proliferator-activated receptor gamma1 (PPARgamma1) overexpression. The Journal of biological chemistry. vol 278. issue 1. 2003-02-10. PMID:12401792. |
of interest is that hepatic steatosis per se, induced either by feeding a diet deficient in choline or developing in fasted pparalpha(-/-) mice, failed to induce the expression of these ppargamma-regulated adipogenesis-related genes in steatotic liver. |
2003-02-10 |
2023-08-12 |
mouse |
| L Tessitore, B Batetta, B Vizio, M F Mulas, B Marengo, S Dess. Cell cholesterol esters and high-density lipoprotein plasma levels during liver hyperplasia in choline-fed male and female rats. International journal of experimental pathology. vol 81. issue 4. 2000-10-06. PMID:10971745. |
continuous choline feeding displaced the liver cholesterol ester pattern and plasma hdl cholesterol levels in females, and in parallel that of dna synthesis, towards those of males. |
2000-10-06 |
2023-08-12 |
rat |
| D Naka. Endogenous liver carcinogenesis in the rat. Pathology international. vol 49. issue 12. 2000-05-10. PMID:10632923. |
however, continuous feeding of a diet deficient in choline and methionine is well known to cause hepatocellular carcinomas (hcc) in rats in the absence of any known exogenous carcinogens and can serve as a good research model. |
2000-05-10 |
2023-08-12 |
rat |
| R G Twibell, P B Brow. Dietary choline requirement of juvenile yellow perch (Perca flavescens). The Journal of nutrition. vol 130. issue 1. 2000-01-21. PMID:10613773. |
we conducted an 11-wk feeding trial to determine the dietary choline requirement of juvenile yellow perch (perca flavescens) and to investigate whether dietary phosphatidylcholine (pc) could meet this requirement. |
2000-01-21 |
2023-08-12 |
Not clear |
| S Y Shiau, P S L. Dietary choline requirements of juvenile hybrid tilapia, Oreochromis niloticus x O. aureus. The Journal of nutrition. vol 130. issue 1. 2000-01-21. PMID:10613774. |
an 8-wk feeding trial was conducted to determine the dietary choline requirement for juvenile hybrid tilapia, oreochromis niloticus x o. aureus. |
2000-01-21 |
2023-08-12 |
Not clear |
| R A Webb, L Xu. The spatial and temporal concentrations of choline in the lumen contents of the small intestine of uninfected and Hymenolepis diminuta infected rats. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. vol 120. issue 4. 1999-07-08. PMID:10400494. |
following feeding, choline levels were significantly elevated to approximately 3 mm by 6 h, although these concentrations fell rapidly in transit down the intestine. |
1999-07-08 |
2023-08-12 |
rat |
| R A Jacob, D J Jenden, M A Allman-Farinelli, M E Swendsei. Folate nutriture alters choline status of women and men fed low choline diets. The Journal of nutrition. vol 129. issue 3. 1999-04-02. PMID:10082779. |
feeding methionine supplements to the men did not prevent plasma choline depletion, indicating that folate is a more limiting nutrient for these methylation pathways. |
1999-04-02 |
2023-08-12 |
rat |
| S Jakob, R Mosenthin, G Huesgen, J Kinkeldei, K J Powelei. Diurnal pattern of choline concentrations in serum of pigs as influenced by dietary choline or lecithin intake. Zeitschrift fur Ernahrungswissenschaft. vol 37. issue 4. 1999-02-25. PMID:9894684. |
all pigs received the basal diet that contained 450 mg/kg choline at the evening feeding (20.00 h). |
1999-02-25 |
2023-08-12 |
Not clear |
| R K Le Leu, G H McIntosh, G P Youn. Ability of endogenous folate from soy protein isolate to maintain plasma homocysteine and hepatic DNA methylation during methyl group depletion in rats. Journal of nutritional science and vitaminology. vol 44. issue 3. 1998-11-24. PMID:9742465. |
we investigated different means of achieving methyl depletion by feeding weanling rats modified ain diets depleted of folate (fd), folate + choline (fcd), and folate + choline + methionine (fcmd), and examined the consequent effects on folate status, homocysteine levels, and methylation status. |
1998-11-24 |
2023-08-12 |
rat |
| C A Rivera, M D Wheeler, N Enomoto, R G Thurma. A choline-rich diet improves survival in a rat model of endotoxin shock. The American journal of physiology. vol 275. issue 4. 1998-11-23. PMID:9756519. |
feeding choline also blunted tumor necrosis factor-alpha production. |
1998-11-23 |
2023-08-12 |
rat |
| C A Rivera, M D Wheeler, N Enomoto, R G Thurma. A choline-rich diet improves survival in a rat model of endotoxin shock. The American journal of physiology. vol 275. issue 4. 1998-11-23. PMID:9756519. |
feeding glycine, which prevents macrophage activation via a chloride channel, in addition to choline was even more effective than feeding choline alone, suggesting that glycine and choline act via distinct sites. |
1998-11-23 |
2023-08-12 |
rat |
| W D SALMON, P M NEWBERN. Cardiovascular disease in choline-deficient rats. Effects of choline deficiency, nature and level of dietary lipids and proteins, and duration of feeding on plasma and liver lipid values and cardiovascular lesions. Archives of pathology. vol 73. 1998-11-01. PMID:14496441. |
effects of choline deficiency, nature and level of dietary lipids and proteins, and duration of feeding on plasma and liver lipid values and cardiovascular lesions. |
1998-11-01 |
2023-08-12 |
rat |
| M Kataria, R Somvanshi, S Das. Biochemical and histological changes in blood, erythrocytes and tissue of rats on feeding Dryopteris juxtaposita fern. Indian journal of experimental biology. vol 36. issue 5. 1998-09-15. PMID:9717467. |
significant increase in lipid peroxidation, atpases and decrease in gst on 80 days post feeding in liver, kidneys and brain and acetyl choline estrase in brain was observed as compared to control. |
1998-09-15 |
2023-08-12 |
rat |
| G W Fink, J G Norma. Specific changes in the pancreatic expression of the interleukin 1 family of genes during experimental acute pancreatitis. Cytokine. vol 9. issue 12. 1998-02-27. PMID:9417814. |
moderate or severe necrotizing pancreatitis was induced by the intraperitoneal injection of a cholecystokinin analogue or the feeding of a choline deficient diet, respectively. |
1998-02-27 |
2023-08-12 |
Not clear |
| E Sesca, M Chiara, V Binasco, F Premoselli, L Tessitor. Choline feeding depresses the phospholipase C activity in the regenerating liver of female rats. Bollettino della Societa italiana di biologia sperimentale. vol 72. issue 11-12. 1997-07-24. PMID:9178584. |
choline feeding depresses the phospholipase c activity in the regenerating liver of female rats. |
1997-07-24 |
2023-08-12 |
rat |
| E Sesca, M Chiara, V Binasco, F Premoselli, L Tessitor. Choline feeding depresses the phospholipase C activity in the regenerating liver of female rats. Bollettino della Societa italiana di biologia sperimentale. vol 72. issue 11-12. 1997-07-24. PMID:9178584. |
choline feeding can affect the phospholipid composition of cell membranes and, as a consequence, the transduction of the mitogenic signals. |
1997-07-24 |
2023-08-12 |
rat |