| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M I Perera, S L Katyal, H Shinozuk. Choline deficient diet enhances the initiating and promoting effects of methapyrilene hydrochloride in rat liver as assayed by the induction of gamma-glutamyltranspeptidase-positive hepatocyte foci. British journal of cancer. vol 56. issue 6. 1988-03-30. PMID:2893639. |
feeding a choline supplemented (cs) or a cd diet containing 0.1% mph for 2 weeks followed by 7 weeks promotion by a cd diet plus phenobarbital was ineffective in inducing ggt-positive foci. |
1988-03-30 |
2023-08-11 |
rat |
| H Dodd, R L Shorey-Kutschk. Ethanol lowers heart carnitine in the methionine and choline deficient rat. Alcohol (Fayetteville, N.Y.). vol 4. issue 5. 1987-12-24. PMID:3675861. |
when ethanol was given as 30% of energy in combination with a diet deficient in methionine and choline, and the feeding period was extended to 5 weeks, heart carnitine levels were significantly affected (experiment 2). |
1987-12-24 |
2023-08-11 |
rat |
| V K Tsiagbe, M E Cook, A E Harper, M L Sund. Enhanced immune responses in broiler chicks fed methionine-supplemented diets. Poultry science. vol 66. issue 7. 1987-11-24. PMID:3671290. |
effects of feeding supplementary methionine and choline on broiler growth and immunity were examined by supplementing a corn-soybean diet that contained 21% crude protein, 3,255 kcal metabolizable energy/kg diet, .35% methionine, .37% cystine, and .13% choline. |
1987-11-24 |
2023-08-11 |
Not clear |
| A K Ghoshal, T H Rushmore, E Farbe. Initiation of carcinogenesis by a dietary deficiency of choline in the absence of added carcinogens. Cancer letters. vol 36. issue 3. 1987-11-09. PMID:2888529. |
the feeding for 10 or 11 weeks of young male fischer-344 rats, a diet devoid of choline and low in methionine, leads to the appearance of gamma-glutamyltransferase-positive foci of altered hepatocytes in the liver and to the induction of initiated resistant hepatocytes. |
1987-11-09 |
2023-08-11 |
rat |
| M Vahter, E Marafant. Effects of low dietary intake of methionine, choline or proteins on the biotransformation of arsenite in the rabbit. Toxicology letters. vol 37. issue 1. 1987-07-10. PMID:3590229. |
the effects of 6 weeks feeding with diets low in methionine, choline, or proteins on the biotransformation and retention of 76as-labelled arsenite (0.4 mg as/kg bw) in rabbits have been studied. |
1987-07-10 |
2023-08-11 |
human |
| N Shivapurkar, M J Wilson, K L Hoover, Y B Mikol, D Creasia, L A Poirie. Hepatic DNA methylation and liver tumor formation in male C3H mice fed methionine- and choline-deficient diets. Journal of the National Cancer Institute. vol 77. issue 1. 1986-08-18. PMID:3459914. |
feeding diet 2, deficient in methionine and choline, to male c3h mice for 5-20 weeks decreased the hepatic ratio of s-adenosylmethionine (cas: 29908-3-0) to s-adenosylhomocysteine (979-92-0) relative to that observed in mice fed the adequate diet 1. |
1986-08-18 |
2023-08-11 |
mouse |
| N Shivapurkar, K L Hoover, L A Poirie. Effect of methionine and choline on liver tumor promotion by phenobarbital and DDT in diethylnitrosamine-initiated rats. Carcinogenesis. vol 7. issue 4. 1986-05-30. PMID:3698186. |
the effect of the chronic feeding of methionine or choline on liver tumor promotion by phenobarbital (phb) or 1,1 bis(p-chlorophenyl)-2,2,2-trichloroethane (ddt) was studied in rats receiving an initiating dose of diethylnitrosamine (den). |
1986-05-30 |
2023-08-11 |
rat |
| N Shivapurkar, K L Hoover, L A Poirie. Effect of methionine and choline on liver tumor promotion by phenobarbital and DDT in diethylnitrosamine-initiated rats. Carcinogenesis. vol 7. issue 4. 1986-05-30. PMID:3698186. |
dietary feeding of methionine and choline either alone or in combination with phb or ddt did not have any significant effect on the incidence of hcc's. |
1986-05-30 |
2023-08-11 |
rat |
| S Lowis, M A Eastwood, W G Brydo. The influence of creatinine, lecithin and choline feeding on aliphatic amine production and excretion in the rat. The British journal of nutrition. vol 54. issue 1. 1985-12-27. PMID:4063314. |
the influence of creatinine, lecithin and choline feeding on aliphatic amine production and excretion in the rat. |
1985-12-27 |
2023-08-11 |
rat |
| S Lowis, M A Eastwood, W G Brydo. The influence of creatinine, lecithin and choline feeding on aliphatic amine production and excretion in the rat. The British journal of nutrition. vol 54. issue 1. 1985-12-27. PMID:4063314. |
the excretion of aliphatic amines, methylamine, dimethylamine and trimethylamine in the urine and faeces of rats fed on a control diet and diets supplemented with creatinine, lecithin or choline were measured over a 14 d feeding period. |
1985-12-27 |
2023-08-11 |
rat |
| R Kramar, K Kremser, R Raa. Enhancement of choline dehydrogenase activity in rat liver mitochondria by clofibrate feeding. Hoppe-Seyler's Zeitschrift fur physiologische Chemie. vol 365. issue 10. 1985-02-25. PMID:6394466. |
enhancement of choline dehydrogenase activity in rat liver mitochondria by clofibrate feeding. |
1985-02-25 |
2023-08-12 |
rat |
| H Shinozuka, S E Abanobi, B Lombard. Modulation of tumor promotion in liver carcinogenesis. Environmental health perspectives. vol 50. 1983-09-23. PMID:6135607. |
earlier, we demonstrated that feeding to rats a diet devoid of choline, a lipotropic factor, markedly enhances hepatoma induction by several chemical carcinogens, and that the diet acts as a strong promoter of the evolution of initiated cells to foci of altered hepatocytes. |
1983-09-23 |
2023-08-12 |
rat |
| A K Ghoshal, E Farbe. The induction of resistant hepatocytes during initiation of liver carcinogenesis with chemicals in rats fed a choline deficient methionine low diet. Carcinogenesis. vol 4. issue 7. 1983-09-09. PMID:6307537. |
feeding a choline deficient methionine low (cld) diet for two weeks can substitute for partial hepatectomy in the genesis with benzo[a]pyrene (b[a]p) or 1,2-dimethylhydrazine (1,2-dmh) of resistant hepatocytes that can be selected with dietary 2-acetylaminofluorene plus partial hepatectomy. |
1983-09-09 |
2023-08-12 |
rat |
| A K Ghoshal, E Farbe. The induction of resistant hepatocytes during initiation of liver carcinogenesis with chemicals in rats fed a choline deficient methionine low diet. Carcinogenesis. vol 4. issue 7. 1983-09-09. PMID:6307537. |
feeding ethionine for 6 or 12 weeks in a similar choline lipotrope deficient diet also induced a significant increase in foci of enzyme altered hepatocytes. |
1983-09-09 |
2023-08-12 |
rat |
| R Sleight, C Ken. Regulation of phosphatidylcholine biosynthesis in mammalian cells. III. Effects of alterations in the phospholipid compositions of Chinese hamster ovary and LM cells on the activity and distribution of CTP:phosphocholine cytidylyltransferase. The Journal of biological chemistry. vol 258. issue 2. 1983-03-11. PMID:6296086. |
the activity and subcellular distribution of ctp:phosphocholine cytidylyltransferase in lm and chinese hamster ovary cells in which the phospholipid composition had been altered by supplementary feeding with choline analogues were examined. |
1983-03-11 |
2023-08-12 |
Not clear |
| N Shivapurkar, L A Poirie. Decreased levels of S-adenosylmethionine in the livers of rats fed phenobarbital and DDT. Carcinogenesis. vol 3. issue 5. 1982-09-24. PMID:7094216. |
such reductions were inhibited by the simultaneous feeding of choline chloride and were completely prevented by the dietary administration of methionine. |
1982-09-24 |
2023-08-12 |
rat |
| A A Alie. [Effect of lipid-inhibiting animal feed containing acetate-mineral additives on choline metabolism in the ruminant stomach and intestines]. Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova. vol 68. issue 4. 1982-08-26. PMID:7084516. |
feeding of the cows with granulated food alone decreases synthesis and excretion of choline whereas acetate-mineral additions restore its level as well as the amount of fat in milk of the cows. |
1982-08-26 |
2023-08-12 |
Not clear |
| R D Boyd, B D Moser, E R Peo, A J Lewis, R K Johnso. Effect of tallow and choline chloride addition to the diet of sows milk composition, milk yield and preweaning pig performance. Journal of animal science. vol 54. issue 1. 1982-08-07. PMID:7085489. |
four trials were conducted with a total of 188 crossbred sows to determine the effect of feeding diets supplemented with tallow (0 or 8%) and choline chloride (220 or 770 mg/kg diet) prior to parturition and during lactation on preweaning pig performance. |
1982-08-07 |
2023-08-12 |
Not clear |
| R M Dawson, D W Grime, D B Lindsa. On the insensitivity of sheep to the almost complete microbial destruction of dietary choline before alimentary-tract absorption. The Biochemical journal. vol 196. issue 2. 1982-02-12. PMID:7316991. |
long-term feeding of [me-3h]choline to sheep produced insignificant labelling of plasma phosphatidylcholine, indicating that more than 99% of the choline body pool was of non-dietary origin. |
1982-02-12 |
2023-08-12 |
rat |
| B de Kruijff, A M van den Besselaar, H van den Bosch, L L van Deene. Inside-outside distribution and diffusion of phosphatidylcholine in rat sarcoplasmic reticulum as determined by 13C NMR and phosphatidylcholine exchange protein. Biochimica et biophysica acta. vol 555. issue 2. 1979-11-28. PMID:476100. |
sarcoplasmic reticulum phosphatidylcholine was enriched with 13c by feeding rats a diet containing [n-me3-13c]choline. |
1979-11-28 |
2023-08-11 |
rat |