| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yong Xie, Lihua Zhang, Bin Zhang, Li Fan. Roles of heat shock factor 1 in isoproterenol\\xe2\\x80\\x91induced myocardial fibrosis in mice. Molecular medicine reports vol 12 issue 4 2016 26239834 |
although it is well known that isoproterenol (iso) causes myocardial hypertrophy and myocardial fibrosis in rats, it has remained elusive whether heat shock factor 1 (hsf1) has a role in this process. |
2016-06-27 |
2023-01-25 |
rat |
| Rebecca A Capel, Emma L Bolton, Wee K Lin, Daniel Aston, Yanwen Wang, Wei Liu, Xin Wang, Rebecca-Ann B Burton, Duncan Bloor-Young, Kai-Ting Shade, Margarida Ruas, John Parrington, Grant C Churchill, Ming Lei, Antony Galione, Derek A Terra. Two-pore Channels (TPC2s) and Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) at Lysosomal-Sarcoplasmic Reticular Junctions Contribute to Acute and Chronic \\xce\\xb2-Adrenoceptor Signaling in the Heart. The Journal of biological chemistry vol 290 issue 50 2016 26438825 |
hearts from tpcn2(-/-) mice chronically exposed to isoproterenol showed less cardiac hypertrophy and increased threshold for arrhythmogenesis compared with wt controls. |
2016-05-10 |
2023-01-25 |
mouse |
| Jennifer L Major, Maysoon Salih, Balwant S Tuan. Interplay between the E2F pathway and \\xce\\xb2-adrenergic signaling in the pathological hypertrophic response of myocardium. Journal of molecular and cellular cardiology vol 84 issue 2016 25944088 |
we assessed the mechanisms of the apparent failure of compensatory hypertrophic growth as well as their response to the \xce\xb2-adrenergic agonist isoproterenol. |
2016-04-07 |
2023-01-25 |
mouse |
| Robrecht Thoonen, Laura Ernande, Juan Cheng, Yasuko Nagasaka, Vincent Yao, Alexandre Miranda-Bezerra, Chan Chen, Wei Chao, Marcello Panagia, David E Sosnovik, Dheeraj Puppala, Antonis A Armoundas, Allyson Hindle, Kenneth D Bloch, Emmanuel S Buys, Marielle Scherrer-Crosbi. Functional brown adipose tissue limits cardiomyocyte injury and adverse remodeling in catecholamine-induced cardiomyopathy. Journal of molecular and cellular cardiology vol 84 issue 2016 25968336 |
isoproterenol infusion increased ctni and myocardial fibrosis and induced left ventricular (lv) hypertrophy in both wt and ucp1(-/-) mice. |
2016-04-07 |
2023-01-25 |
mouse |
| Nouf M Al-Rasheed, Maha M Al-Oteibi, Reem Z Al-Manee, Sarah A Al-Shareef, Nawal M Al-Rasheed, Iman H Hasan, Raeesa A Mohamad, Ayman M Mahmou. Simvastatin prevents isoproterenol-induced cardiac hypertrophy through modulation of the JAK/STAT pathway. Drug design, development and therapy vol 9 issue 2016 26150695 |
the present study was designed to investigate the effect of pretreatment with sim on isoproterenol (iso)-induced cardiac hypertrophy in rats. |
2016-03-29 |
2023-01-25 |
rat |
| Aina Luan, Futian Tang, Yuhong Yang, Meili Lu, Hongxin Wang, Yingjie Zhan. Astragalus polysaccharide attenuates isoproterenol-induced cardiac hypertrophy by regulating TNF-\\xce\\xb1/PGC-1\\xce\\xb1 signaling mediated energy biosynthesis. Environmental toxicology and pharmacology vol 39 issue 3 2016 25880160 |
bge, attenuates hypertrophy of neonatal rat ventricular myocytes (nrvms) induced by isoproterenol (iso). |
2016-03-22 |
2023-01-25 |
rat |
| Hassan N Althurwi, Zaid H Maayah, Osama H Elshenawy, Ayman O S El-Kad. Early Changes in Cytochrome P450s and Their Associated Arachidonic Acid Metabolites Play a Crucial Role in the Initiation of Cardiac Hypertrophy Induced by Isoproterenol. Drug metabolism and disposition: the biological fate of chemicals vol 43 issue 8 2016 26033621 |
early changes in cytochrome p450s and their associated arachidonic acid metabolites play a crucial role in the initiation of cardiac hypertrophy induced by isoproterenol. |
2016-03-10 |
2023-01-25 |
rat |
| Hassan N Althurwi, Zaid H Maayah, Osama H Elshenawy, Ayman O S El-Kad. Early Changes in Cytochrome P450s and Their Associated Arachidonic Acid Metabolites Play a Crucial Role in the Initiation of Cardiac Hypertrophy Induced by Isoproterenol. Drug metabolism and disposition: the biological fate of chemicals vol 43 issue 8 2016 26033621 |
to test our hypothesis, rats and rl-14 cells were treated with the hypertrophic agonist isoproterenol for different time periods. |
2016-03-10 |
2023-01-25 |
rat |
| Hassan N Althurwi, Zaid H Maayah, Osama H Elshenawy, Ayman O S El-Kad. Early Changes in Cytochrome P450s and Their Associated Arachidonic Acid Metabolites Play a Crucial Role in the Initiation of Cardiac Hypertrophy Induced by Isoproterenol. Drug metabolism and disposition: the biological fate of chemicals vol 43 issue 8 2016 26033621 |
our results show that in vivo and in vitro hypertrophy was initiated after 72 hours and 6 hours of isoproterenol treatment, respectively. |
2016-03-10 |
2023-01-25 |
rat |
| Benzhi Cai, Xueying Tan, Yong Zhang, Xingda Li, Xinyue Wang, Jiuxin Zhu, Yang Wang, Fan Yang, Baoqiu Wang, Yanju Liu, Chaoqian Xu, Zhenwei Pan, Ning Wang, Baofeng Yang, Yanjie L. Mesenchymal Stem Cells and Cardiomyocytes Interplay to Prevent Myocardial Hypertrophy. Stem cells translational medicine vol 4 issue 12 2016 26586774 |
the results showed that isoproterenol (iso)-induced typical hypertrophic characteristics of cardiomyocytes were prevented by bmscs in the coculture model in vitro and after bmsc transplantation in vivo. |
2016-02-23 |
2023-01-25 |
rat |
| Xiao-Jun Feng, Hui Gao, Si Gao, Zhuoming Li, Hong Li, Jing Lu, Jiao-Jiao Wang, Xiao-Yang Huang, Min Liu, Jian Zou, Jian-Tao Ye, Pei-Qing Li. The orphan receptor NOR1 participates in isoprenaline-induced cardiac hypertrophy by regulating PARP-1. British journal of pharmacology vol 172 issue 11 2016 25625556 |
here, the roles of nor1 in cardiac hypertrophy induced by isoprenaline and the underlying molecular mechanisms were investigated. |
2016-02-16 |
2023-01-25 |
Not clear |
| Francisco Rodrigo Lemos Caldas, Iago Mateus Rocha Leite, Ana Beatriz Tavarez Filgueiras, Isaias Lima de Figueiredo J\\xc3\\xbanior, Tereza Am\\xc3\\xa1lia Gomes Marques de Sousa, Pamela Reis Martins, Alicia Juliana Kowaltowski, Heberty di Tarso Fernandes Facund. Mitochondrial ATP-sensitive potassium channel opening inhibits isoproterenol-induced cardiac hypertrophy by preventing oxidative damage. Journal of cardiovascular pharmacology vol 65 issue 4 2016 25850726 |
in this study, we show that treatment of swiss mice with isoproterenol (30 mg\xc2\xb7kg\xc2\xb7d) induces cardiac hypertrophy while significantly decreasing the levels of reduced protein thiols, glutathione, catalase, and superoxide dismutase activity, indicative of a condition of oxidative imbalance. |
2016-02-01 |
2023-01-25 |
mouse |
| Ashfaq Ahmad, Munavvar Z A Sattar, Hassaan A Rathore, Safia Akhtar Khan, Mohammed A Lazhari, Fayaz Hashmi, Nor A Abdullah, Edward J John. IMPACT OF ISOPRENALINE AND CAFFEINE ON DEVELOPMENT OF LEFT VENTRICULAR HYPERTROPHY AND RENAL HEMODYNAMIC IN WISTAR KYOTO RATS. Acta poloniae pharmaceutica vol 72 issue 5 2016 26665409 |
impact of isoprenaline and caffeine on development of left ventricular hypertrophy and renal hemodynamic in wistar kyoto rats. |
2016-01-11 |
2023-01-25 |
rat |
| Ashfaq Ahmad, Munavvar Z A Sattar, Hassaan A Rathore, Safia Akhtar Khan, Mohammed A Lazhari, Fayaz Hashmi, Nor A Abdullah, Edward J John. IMPACT OF ISOPRENALINE AND CAFFEINE ON DEVELOPMENT OF LEFT VENTRICULAR HYPERTROPHY AND RENAL HEMODYNAMIC IN WISTAR KYOTO RATS. Acta poloniae pharmaceutica vol 72 issue 5 2016 26665409 |
in conclusion, isoprenaline and caffeine (i/c) induces lvh and cardiac hypertrophy with increases in blood pressure, fluid excretion and reduced renal hemodynamics. |
2016-01-11 |
2023-01-25 |
rat |
| Suping Zhang, Futian Tang, Yuhong Yang, Meili Lu, Aina Luan, Jing Zhang, Juan Yang, Hongxin Wan. Astragaloside IV protects against isoproterenol-induced cardiac hypertrophy by regulating NF-\\xce\\xbaB/PGC-1\\xce\\xb1 signaling mediated energy biosynthesis. PloS one vol 10 issue 3 2015 25738576 |
we previously reported that astragaloside iv (asiv), a major active constituent of astragalus membranaceus (fisch) bge protects against cardiac hypertrophy in rats induced by isoproterenol (iso), however the mechanism underlying the protection remains unknown. |
2015-12-03 |
2023-01-25 |
rat |
| Guijun Yan, Ni Zhu, Shengdong Huang, Bing Yi, Xiying Shang, Ming Chen, Nadan Wang, Guan-xin Zhang, Jennifer A Talarico, Douglas G Tilley, Erhe Gao, Jianxin Su. Orphan Nuclear Receptor Nur77 Inhibits Cardiac Hypertrophic Response to Beta-Adrenergic Stimulation. Molecular and cellular biology vol 35 issue 19 2015 26195821 |
by using northern blot, western blot, and immunofluorescent staining assays, we showed that nur77 expression was markedly upregulated in cardiomyocytes in response to multiple hypertrophic stimuli, including isoproterenol (iso), phenylephrine (pe), and endothelin-1 (et-1). |
2015-12-03 |
2023-01-25 |
mouse |
| Ji-Min Sun, Chun-Miao Wang, Zeng Guo, Yu-Yu Hao, Yang-Jing Xie, Jian Gu, Ai-Ling Wan. Reduction of isoproterenol-induced cardiac hypertrophy and modulation of myocardial connexin43 by a KATP channel agonist. Molecular medicine reports vol 11 issue 3 2015 25411819 |
the aim of this study was to investigate whether an atp\xe2\x80\x91sensitive k+ (katp) channel agonist was capable of reducing isoproterenol (iso)\xe2\x80\x91induced cardiac hypertrophy and modulating myocardial connexin43 (cx43) expression. |
2015-10-12 |
2023-01-25 |
rat |
| Martin Andrews, Maryellen L Giger, Brian B Roma. Manganese-enhanced MRI detection of impaired calcium regulation in a mouse model of cardiac hypertrophy. NMR in biomedicine vol 28 issue 2 2015 25523065 |
hypertrophy was induced via subcutaneous continuous 3-day infusion of isoproterenol, and sham mice not subjected to cardiac hypertrophy were also imaged. |
2015-09-14 |
2023-01-25 |
mouse |
| C Z Yang, A J Tian, Z H Meng, J M Wu, Y Y Zhang, L J Guo, Z J L. [Establishment of a FVB/N mouse model of cardiac hypertrophy by isoprenaline]. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences vol 46 issue 6 2015 25512281 |
[establishment of a fvb/n mouse model of cardiac hypertrophy by isoprenaline]. |
2015-09-08 |
2023-01-25 |
mouse |
| C Z Yang, A J Tian, Z H Meng, J M Wu, Y Y Zhang, L J Guo, Z J L. [Establishment of a FVB/N mouse model of cardiac hypertrophy by isoprenaline]. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences vol 46 issue 6 2015 25512281 |
to investigate the condition of isoprenaline (iso)-induced cardiac hypertrophy in the fvb/n mouse. |
2015-09-08 |
2023-01-25 |
mouse |