| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| James S Meabon, Bertrand R Huber, Donna J Cross, Todd L Richards, Satoshi Minoshima, Kathleen F Pagulayan, Ge Li, Kole D Meeker, Brian C Kraemer, Eric C Petrie, Murray A Raskind, Elaine R Peskind, David G Coo. Repetitive blast exposure in mice and combat veterans causes persistent cerebellar dysfunction. Science translational medicine. vol 8. issue 321. 2016-12-13. PMID:26764157. |
purkinje cell loss was most pronounced in the ventral cerebellar lobules, suggesting that early-stage breakdown of bbb integrity may be an important factor driving long-term brain changes. |
2016-12-13 |
2023-08-13 |
mouse |
| Giorgio Grasselli, Qionger He, Vivian Wan, John P Adelman, Gen Ohtsuki, Christian Hanse. Activity-Dependent Plasticity of Spike Pauses in Cerebellar Purkinje Cells. Cell reports. vol 14. issue 11. 2016-12-13. PMID:26972012. |
our findings demonstrate that spike pauses can be regulated through an activity-dependent, exclusively non-synaptic, sk2 channel-dependent mechanism and suggest that pause plasticity-by altering the purkinje cell output-may be crucial to cerebellar information storage and learning. |
2016-12-13 |
2023-08-13 |
mouse |
| Jan Voog. Deiters' Nucleus. Its Role in Cerebellar Ideogenesis : The Ferdinando Rossi Memorial Lecture. Cerebellum (London, England). vol 15. issue 1. 2016-10-21. PMID:26054378. |
this nucleus, however, should be considered as a cerebellar nucleus because it receives purkinje cell axons from the vermal b zone in its dorsal portion. |
2016-10-21 |
2023-08-13 |
human |
| Jan Cendeli. Transplantation and Stem Cell Therapy for Cerebellar Degenerations. Cerebellum (London, England). vol 15. issue 1. 2016-10-21. PMID:26155762. |
in purkinje cell degeneration mice, lurcher mutant mice and mouse models of spinocerebellar ataxia type 1 and type 2 and niemann-pick disease type c. despite the lack of direct comparative studies, it appears that there might be differences in graft development and functioning between various types of cerebellar degeneration. |
2016-10-21 |
2023-08-13 |
mouse |
| Roy V Sillito. Mossy Fibers Terminate Directly Within Purkinje Cell Zones During Mouse Development. Cerebellum (London, England). vol 15. issue 1. 2016-10-21. PMID:26255945. |
at the center of every zone is the purkinje cell, the principal cell type of the cerebellum and sole output of the cerebellar cortex. |
2016-10-21 |
2023-08-13 |
mouse |
| Roy V Sillito. Mossy Fibers Terminate Directly Within Purkinje Cell Zones During Mouse Development. Cerebellum (London, England). vol 15. issue 1. 2016-10-21. PMID:26255945. |
the traced purkinje cell zones formed a zebrin-like pattern that was defined by the expression of neurofilament heavy chain (nfh), a marker of zones in the postnatal developing cerebellum. |
2016-10-21 |
2023-08-13 |
mouse |
| Maryam Rahimi Balaei, Xiaodan Jiao, Niloufar Ashtari, Pegah Afsharinezhad, Saeid Ghavami, Hassan Marzba. Cerebellar Expression of the Neurotrophin Receptor p75 in Naked-Ataxia Mutant Mouse. International journal of molecular sciences. vol 17. issue 1. 2016-10-20. PMID:26784182. |
spontaneous mutation in the lysosomal acid phosphatase 2 (acp2) mouse (nax--naked-ataxia mutant mouse) correlates with severe cerebellar defects including ataxia, reduced size and abnormal lobulation as well as purkinje cell (pc) degeneration. |
2016-10-20 |
2023-08-13 |
mouse |
| Joshua J White, Marife Arancillo, Annesha King, Tao Lin, Lauren N Miterko, Samrawit A Gebre, Roy V Sillito. Pathogenesis of severe ataxia and tremor without the typical signs of neurodegeneration. Neurobiology of disease. vol 86. 2016-10-14. PMID:26586559. |
we found that faulty molecular patterning, which shapes functional circuits called zones, leads to alterations in cerebellar wiring and purkinje cell activity, but not to degeneration. |
2016-10-14 |
2023-08-13 |
mouse |
| Antonella Bizzoca, Sabrina Picocci, Patrizia Corsi, Stefania Arbia, Laura Croci, G Giacomo Consalez, Gianfranco Gennarin. The gene encoding the mouse contactin-1 axonal glycoprotein is regulated by the collier/Olf1/EBF family early B-Cell factor 2 transcription factor. Developmental neurobiology. vol 75. issue 12. 2016-10-11. PMID:25820347. |
likewise, null mutant mice for the collier/olf1/early b-cell family transcription factor ebf2, in which purkinje neuron development is primarily affected, exhibit abnormalities in cerebellar corticogenesis. |
2016-10-11 |
2023-08-13 |
mouse |
| Han-Sam Cho, Tae-Woon Kim, Eun-Sang Ji, Hye-Sang Park, Mal-Soon Shin, Seung-Soo Bae. Treadmill exercise ameliorates motor dysfunction through inhibition of Purkinje cell loss in cerebellum of valproic acid-induced autistic rats. Journal of exercise rehabilitation. vol 12. issue 4. 2016-09-22. PMID:27656625. |
treadmill exercise ameliorates motor dysfunction through inhibition of purkinje cell loss in cerebellum of valproic acid-induced autistic rats. |
2016-09-22 |
2023-08-13 |
rat |
| Han-Sam Cho, Tae-Woon Kim, Eun-Sang Ji, Hye-Sang Park, Mal-Soon Shin, Seung-Soo Bae. Treadmill exercise ameliorates motor dysfunction through inhibition of Purkinje cell loss in cerebellum of valproic acid-induced autistic rats. Journal of exercise rehabilitation. vol 12. issue 4. 2016-09-22. PMID:27656625. |
in the present study, we evaluated the effect of treadmill exercise on the motor coordination and purkinje cell loss in relation with reactive astrocytes and microglial activation in the cerebellum using valproic acid (vpa)-induced autism rat model. |
2016-09-22 |
2023-08-13 |
rat |
| Joaquín Martí, M C Santa-Cruz, Roger Serra, José P Hervá. Systematic differences in time of cerebellar-neuron origin derived from bromodeoxyuridine immunoperoxidase staining protocols and tritiated thymidine autoradiography: A comparative study. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 47. issue Pt B. 2016-09-16. PMID:26434379. |
we observed that, in comparison to the saline group, several parameters of the cerebellum such as length of the cerebellar cortex, the area of the molecular layer, purkinje cell (pcs) number, the areas of the cerebellar nuclei, and the number of the deep cerebellar nuclei (dcn) neurons were lower in the brdu injected group. |
2016-09-16 |
2023-08-13 |
mouse |
| Jonathan Fleming, Chin Chian. The Purkinje neuron: A central orchestrator of cerebellar neurogenesis. Neurogenesis (Austin, Tex.). vol 2. issue 1. 2016-09-08. PMID:27604220. |
the purkinje neuron: a central orchestrator of cerebellar neurogenesis. |
2016-09-08 |
2023-08-13 |
Not clear |
| Jonathan Fleming, Chin Chian. The Purkinje neuron: A central orchestrator of cerebellar neurogenesis. Neurogenesis (Austin, Tex.). vol 2. issue 1. 2016-09-08. PMID:27604220. |
recent work has demonstrated that the purkinje neuron, the central integrator of signaling within the cerebellar system, acts during development to ensure that neurogenesis occurring in spatially opposed domains reaches completion by transmitting the sonic hedgehog ligand bi-directionally. |
2016-09-08 |
2023-08-13 |
Not clear |
| Anand Venkatraman, Puneet Opa. Paraneoplastic cerebellar degeneration with anti-Yo antibodies - a review. Annals of clinical and translational neurology. vol 3. issue 8. 2016-09-08. PMID:27606347. |
the ataxic syndrome associated with anti-yo antibody, or purkinje cell cytoplasmic antibody type 1 (pca1), is the most common variant of paraneoplastic cerebellar degeneration (pcd). |
2016-09-08 |
2023-08-13 |
Not clear |
| P De Bartolo, F Florenzano, L Burello, F Gelfo, L Petrosin. Activity-dependent structural plasticity of Purkinje cell spines in cerebellar vermis and hemisphere. Brain structure & function. vol 220. issue 5. 2016-08-19. PMID:25023735. |
activity-dependent structural plasticity of purkinje cell spines in cerebellar vermis and hemisphere. |
2016-08-19 |
2023-08-13 |
rat |
| P De Bartolo, F Florenzano, L Burello, F Gelfo, L Petrosin. Activity-dependent structural plasticity of Purkinje cell spines in cerebellar vermis and hemisphere. Brain structure & function. vol 220. issue 5. 2016-08-19. PMID:25023735. |
thus, aim of the present study was to characterize the ee effects on density and size of dendritic spines of purkinje cell proximal and distal compartments in cerebellar vermian and hemispherical regions. |
2016-08-19 |
2023-08-13 |
rat |
| P De Bartolo, F Florenzano, L Burello, F Gelfo, L Petrosin. Activity-dependent structural plasticity of Purkinje cell spines in cerebellar vermis and hemisphere. Brain structure & function. vol 220. issue 5. 2016-08-19. PMID:25023735. |
the morphological features of purkinje cell spines were visualized on calbindin immunofluorescence-stained cerebellar vermian and hemispherical sections. |
2016-08-19 |
2023-08-13 |
rat |
| Supriya Swarnkar, Youjun Chen, William M Pryor, Neelam Shahani, Damon T Page, Srinivasa Subramania. Ectopic expression of the striatal-enriched GTPase Rhes elicits cerebellar degeneration and an ataxia phenotype in Huntington's disease. Neurobiology of disease. vol 82. 2016-08-19. PMID:26048156. |
pathological and biochemical analysis of rhes-injected n171-82q mice revealed a cerebellar lesion with marked loss of purkinje neuron layer parvalbumin-immunoreactivity, induction of caspase 3 activation, and enhanced soluble forms of mhtt. |
2016-08-19 |
2023-08-13 |
mouse |
| Kenji Sakai, Chiho Ishida, Akiyoshi Morinaga, Kazuya Takahashi, Masahito Yamad. Case Study: Somatic Sprouts and Halo-Like Amorphous Materials of the Purkinje Cells in Huntington's Disease. Cerebellum (London, England). vol 14. issue 6. 2016-08-15. PMID:25962893. |
the cerebellum was macroscopically unremarkable; however, somatic sprouts and halo-like amorphous materials of purkinje cell with a large amount of torpedoes were noteworthy. |
2016-08-15 |
2023-08-13 |
Not clear |