| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ryoji Goto, Masanori Kurihara, Masashi Kameyama, Hiroki Komatsu, Masashi Higashino, Keiko Hatano, Ryoko Ihara, Mana Higashihara, Yasushi Nishina, Tomoyasu Matsubara, Kazutomi Kanemaru, Yuko Saito, Shigeo Murayama, Atsushi Iwat. Correlations between cerebrospinal fluid homovanillic acid and dopamine transporter SPECT in degenerative parkinsonian syndromes. Journal of neural transmission (Vienna, Austria : 1996) vol issue 2023 36871130 |
both cerebrospinal fluid (csf) homovanillic acid (hva) and striatal dopamine transporter (dat) binding on single-photon emission computed tomography (spect) reflect nigrostriatal dopaminergic function, but studies on the relationship between the two have been limited. |
2023-03-04 |
2023-03-06 |
human |
| Laura Hautrive Milanesi, Domenika Rubert Rossato, J\\xc3\\xa9ssica Leandra Oliveira Rosa, L\\xc3\\xadvia Ferraz D'avila, Vin\\xc3\\xadcia Garzella Metz, Camila Reck Rampelotto, Viviane Gon\\xc3\\xa7alves Pereira, Scheila Rezende Schaffazick, Cristiane de Bona da Silva, Marilise E Burge. Ferulic acid-loaded nanostructure prevents morphine reinstatement: the involvement of dopamine system, NRF2, and \\xce\\x94FosB in the striatum brain area of rats. Naunyn-Schmiedeberg's archives of pharmacology vol issue 2023 36790483 |
morphine exposure increased the dopaminergic markers (d1r, d3r, dat) and \xce\x94fosb immunoreactivity in the ventral striatum; however, fa-nc treatment decreased d1r, d3r, and \xce\x94fosb and increased d2r, dat, and nrf2. |
2023-02-15 |
2023-03-06 |
rat |
| Daniel Kalinowski, Krystyna Bogus-Nowakowska, Anna Koz\\xc5\\x82owska, Maciej R\\xc3\\xb3wnia. Dopaminergic and cholinergic modulation of the amygdala is altered in female mice with oestrogen receptor \\xce\\xb2 deprivation. Scientific reports vol 13 issue 1 2023 36650256 |
the results show that among dopaminergic markers, the expression of tyrosine hydroxylase (th), dopamine transporter (dat) and dopamine d |
2023-01-17 |
2023-01-30 |
mouse |
| Patrick J Kearney, Nicholas C Bolden, Elizabeth Kahuno, Tucker L Conklin, Gilles E Martin, Gert Lubec, Haley E Melikia. Presynaptic Gq-coupled receptors drive biphasic dopamine transporter trafficking that modulates dopamine clearance and motor function. The Journal of biological chemistry vol issue 2023 36640864 |
despite its necessity for da neurotransmission, dat regulation in situ is poorly understood, and it is unknown whether regulated dat trafficking impacts dopaminergic signaling and/or behaviors. |
2023-01-14 |
2023-01-30 |
Not clear |
| Patrick J Kearney, Nicholas C Bolden, Elizabeth Kahuno, Tucker L Conklin, Gilles E Martin, Gert Lubec, Haley E Melikia. Presynaptic Gq-coupled receptors drive biphasic dopamine transporter trafficking that modulates dopamine clearance and motor function. The Journal of biological chemistry vol issue 2023 36640864 |
further, dopaminergic mglu5 silencing elevated dat surface expression and abolished motor learning, which was rescued by inhibiting dat with a subthreshold ce-158 dose. |
2023-01-14 |
2023-01-30 |
Not clear |
| Riccardo Camedda, Chiara Giuseppina Bonomi, Martina Gaia Di Donna, Agostino Chiaravallot. Functional Correlates of Striatal Dopamine Transporter Cerebrospinal Fluid Levels in Alzheimer's Disease: A Preliminary International journal of molecular sciences vol 24 issue 1 2023 36614193 |
results indicate that patients with higher csf dat levels have a better metabolic pattern in two key zones, suggesting less advanced disease status in patients with more conserved dopaminergic systems. |
2023-01-08 |
2023-01-30 |
Not clear |
| Tahereh Ghaedian, Ali Razmkon, Leila Kalhor, Vahid Reza Ostovan, Omid Yousefi, Raziyeh Rezaei, Mohammad Reza Hossein-Tehrani, Abbas Rakhsh. Correlation of response to subthalamic deep brain stimulation in Parkinson's disease patients with striatal dopamine transporter density on 99mtc-TRODAT-1 SPECT. Neurological research vol issue 2022 36573915 |
since the loss of dopaminergic neurons in the substantia nigra is the main pathophysiology of pd, we aimed to evaluate the association of response to dbs with preoperative dopamine transporter density (dat) and its postoperative changes in pd patients who underwent the bilateral implantation of the electrodes in the subthalamic nucleus (stn). |
2022-12-27 |
2023-01-30 |
Not clear |
| Ciara Frances Pugh, Brian Thomas DeVree, Solveig Gaarde Schmidt, Claus Juul Lolan. Pharmacological Characterization of Purified Full-Length Dopamine Transporter from Cells vol 11 issue 23 2022 36497070 |
pharmacological characterization of purified full-length dopamine transporter from the dopamine transporter (dat) is a member of the neurotransmitter:sodium symporter (nss) family, mediating the sodium-driven reuptake of dopamine from the extracellular space thereby terminating dopaminergic neurotransmission. |
2022-12-11 |
2023-01-30 |
Not clear |
| Jing Deng, Xirong Zheng, Linyue Shang, Chang-Guo Zhan, Fang Zhen. Gender differences in cocaine-induced hyperactivity and dopamine transporter trafficking to the plasma membrane. Addiction biology vol 27 issue 6 2022 36301205 |
as well known, cocaine induces stimulant effects and dopamine transporter (dat) trafficking to the plasma membrane of dopaminergic neurons. |
2022-10-27 |
2023-01-30 |
rat |
| Jing Deng, Xirong Zheng, Linyue Shang, Chang-Guo Zhan, Fang Zhen. Gender differences in cocaine-induced hyperactivity and dopamine transporter trafficking to the plasma membrane. Addiction biology vol 27 issue 6 2022 36301205 |
in the present study, we examined cocaine-induced hyperactivity along with cocaine-induced dat trafficking and the recovery rate of the dopaminergic system in female rats in comparison with male rats, demonstrating interesting gender differences. |
2022-10-27 |
2023-01-30 |
rat |
| Matthew D Lycas, Aske L Ejdrup, Andreas T S\\xc3\\xb8rensen, Nicolai O Haahr, S\\xc3\\xb8ren H J\\xc3\\xb8rgensen, Daryl A Guthrie, Jonatan F St\\xc3\\xb8ier, Christian Werner, Amy Hauck Newman, Markus Sauer, Freja Herborg, Ulrik Gethe. Nanoscopic dopamine transporter distribution and conformation are inversely regulated by excitatory drive and D2 autoreceptor activity. Cell reports vol 40 issue 13 2022 36170827 |
here we show, by application of several super-resolution microscopy techniques to cultured neurons and mouse striatal slices, that the da transporter (dat), a key protein in varicosities of dopaminergic neurons, exists in the membrane in dynamic equilibrium between an inward-facing nanodomain-localized and outward-facing unclustered configuration. |
2022-09-28 |
2023-01-30 |
mouse |
| Milca Abda Morais, Beatriz Silva Franco, Alessandro Spencer Souza Holanda, La\\xc3\\xads Ang\\xc3\\xa9lica de Paula Simino, Alana Carolina Costa Veras, Marcio Alberto Torsoni, Mauro Manconi, Adriana Souza Torsoni, Andrea Maculano Esteve. Protein tyrosine phosphatase receptor type delta (PTPRD) gene in an animal model of restless legs syndrome. Journal of sleep research vol issue 2022 36053904 |
to evaluate the tyrosine hydroxylase enzyme, dopamine transporter (dat) and type 2 dopaminergic receptor, qpcr and western blotting techniques were used. |
2022-09-02 |
2023-01-30 |
rat |
| Xiaosan Tang, Heng Li, Baozeng An, Haibo Ma, Nana Huang, Xiaohong L. Transplantation of human cord blood-derived multipotent stem cells (CB-SCs) enhances the recovery of Parkinson in rats. Transplant immunology vol issue 2022 36038047 |
after being transplanted into the striatum and substantia nigra of pd rats, most of cb-scs (>90%) developed a fate commitment to dopaminergic differentiation, expressed as the expression of tyrosine hydroxylase (th) and dopamine transporter (dat). |
2022-08-29 |
2023-01-30 |
rat |
| Takehiro Tamura, Genichi Sugihara, Kyoji Okita, Yohei Mukai, Hiroshi Matsuda, Hiroki Shiwaku, Shunsuke Takagi, Hiromitsu Daisaki, Ukihide Tateishi, Hidehiko Takahash. Dopamine dysfunction in depression: application of texture analysis to dopamine transporter single-photon emission computed tomography imaging. Translational psychiatry vol 12 issue 1 2022 35922402 |
however, results of recent neuroimaging studies on dopamine transporter (dat), which reflect the function of the dopaminergic system, are inconclusive. |
2022-08-03 |
2023-01-30 |
Not clear |
| Dag Nyholm, Wolfgang H Jos. Levodopa-entacapone-carbidopa intestinal gel infusion in advanced Parkinson's disease: real-world experience and practical guidance. Therapeutic advances in neurological disorders vol 15 issue 2022 35785401 |
at this point, patients may wish to consider a device-aided therapy (dat) that provides continuous dopaminergic stimulation to help overcome these issues. |
2022-07-05 |
2023-01-27 |
Not clear |
| Jing Deng, Ting Zhang, Xirong Zheng, Linyue Shang, Chang-Guo Zhan, Fang Zhen. Recovery of dopaminergic system after cocaine exposure and impact of a long-acting cocaine hydrolase. Addiction biology vol 27 issue 4 2022 35754103 |
dysregulation of dopamine transporters (dat) within the dopaminergic system is an important biomarker of cocaine exposure. |
2022-06-27 |
2023-01-27 |
rat |
| Jing Deng, Ting Zhang, Xirong Zheng, Linyue Shang, Chang-Guo Zhan, Fang Zhen. Recovery of dopaminergic system after cocaine exposure and impact of a long-acting cocaine hydrolase. Addiction biology vol 27 issue 4 2022 35754103 |
depending on cocaine amount in-taken, one-time exposure in rats could lead to most (>95% of total) of dat translocating to plasma membrane of the dopaminergic neurons compared to normal dat distribution (~5.7% on the plasma membrane). |
2022-06-27 |
2023-01-27 |
rat |
| Jing Deng, Ting Zhang, Xirong Zheng, Linyue Shang, Chang-Guo Zhan, Fang Zhen. Recovery of dopaminergic system after cocaine exposure and impact of a long-acting cocaine hydrolase. Addiction biology vol 27 issue 4 2022 35754103 |
without further cocaine exposure, the time course of striatal dat distribution, in terms of intracellular and plasma membrane fractions of dat, represents a recovery process of the dopaminergic system. |
2022-06-27 |
2023-01-27 |
rat |
| Jing Deng, Ting Zhang, Xirong Zheng, Linyue Shang, Chang-Guo Zhan, Fang Zhen. Recovery of dopaminergic system after cocaine exposure and impact of a long-acting cocaine hydrolase. Addiction biology vol 27 issue 4 2022 35754103 |
the cocaine hydrolase protected dopaminergic system and helped the cocaine-altered dat distribution to recover by preventing the dopaminergic system from further damage by cocaine. |
2022-06-27 |
2023-01-27 |
rat |
| Eric Gyimah, Xian Zhu, Ziqi Zhang, Mengyuan Guo, Hai Xu, John Kenneth Mensah, Xing Dong, Zhen Zhang, Godfred Nana Wireko Gyima. Oxidative Stress and Apoptosis in Bisphenol AF-induced Neurotoxicity in Zebrafish Embryos. Environmental toxicology and chemistry vol issue 2022 35723417 |
moreover, qpcr results depicted that bpaf (0.3 \xce\xbcm and 1.0 \xce\xbcm) significantly altered the normal dopaminergic signalling where dat was upregulated, while drd2a and th1 were downregulated, in a concentration-dependent manner. |
2022-06-20 |
2023-01-27 |
cat |