All Relations between hypertrophic and matrix compartment

Reference Sentence Publish Date Extraction Date Species
Qing Zhang, Lin Shi, Hong He, Xingmou Liu, Yong Huang, Dan Xu, Mengyun Yao, Ning Zhang, Yicheng Guo, Yifei Lu, Haisheng Li, Junyi Zhou, Jianglin Tan, Malcolm Xing, Gaoxing Lu. Down-Regulating Scar Formation by Microneedles Directly ACS nano vol issue 2022 35617518 down-regulating scar formation by microneedles directly excessive extracellular matrix deposition drives fibroblasts into a state of high mechanical stress, exacerbating pathological fibrosis and hypertrophic scar formation, leading to tissue dysfunction. 2022-05-26 2023-01-27 rabbit
Maria Barilli, Maria Cristina Tavera, Serafina Valente, Alberto Palazzuol. Structural and Hemodynamic Changes of the Right Ventricle in PH-HFpEF. International journal of molecular sciences vol 23 issue 9 2022 35562945 conversely, ph related to hfpef is primarily due to an increase of venules/capillaries parietal fibrosis, extracellular matrix deposition, and myocyte hypertrophy with a secondary "arteriolarization" of the vessels. 2022-05-14 2023-01-27 Not clear
Joshua S Godwin, Bradley Ruple, Casey Sexton, Morgan Smith, Andrew Fruge, Kaelin Young, Christopher Mobley, Michael Robert. Extracellular Matrix Content and Remodeling Does Not Differ Between Higher-Responders and Lower-Responders to Resistance Training. FASEB journal : official publication of the Federation of American Societies for Experimental Biology vol 36 Suppl 1 issue 2022 35555323 to determine if markers of skeletal muscle extracellular matrix (ecm) content and ecm remodeling are indicators of hypertrophy in previously untrained collage aged males. 2022-05-13 2023-01-27 Not clear
Chen Chen, Xiyu Zhang, Cuiting Zheng, Zhenqiang Gao, Xi Jiang, Yunfei Bai, Yan Men. Sulfasalazine exacerbates Angiotensin II induced cardiac remodeling by activating Akt signal pathway. Clinical and experimental pharmacology & physiology vol issue 2022 35538895 angiotensin ii (ang ii) results in cardiac fibrosis and hypertrophy partly through activation of inflammation, which increases the fibroblasts and promotes extracellular matrix production. 2022-05-11 2023-01-27 mouse
Abu Mohammad Syed, Sourav Kundu, Chetan Ram, Uttam Kulhari, Akhilesh Kumar, Madhav Nilakanth Mugale, Purusottam Mohapatra, Upadhyayula Suryanarayana Murty, Bidya Dhar Sah. Up-regulation of Nrf2/HO-1 and inhibition of TGF-\\xce\\xb21/Smad2/3 signaling axis by daphnetin alleviates transverse aortic constriction-induced cardiac remodeling in mice. Free radical biology & medicine vol issue 2022 35513128 oxidative damage and accumulation of extracellular matrix (ecm) components play a crucial role in the adverse outcome of cardiac hypertrophy. 2022-05-05 2023-01-27 mouse
Kyle Sylakowski, Mintai Peter Hwang, Amritha Justin, Diana Whaley, Yadong Wang, Alan Well. The matricellular protein decorin delivered intradermally with coacervate improves wound resolution in the CXCR3-deficient mouse model of hypertrophic scarring. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society vol issue 2022 35470921 we investigated the use of decorin as a therapeutic by administering the matrix protein anchored in a slow-release coacervate in a hypertrophic scarring mouse model. 2022-04-26 2023-01-27 mouse
Gianluca Di Bella, Francesco Cappelli, Roberto Licordari, Paolo Piaggi, Mariapaola Campisi, Diego Bellavia, Fabio Minutoli, Luca Gentile, Massimo Russo, Cesare de Gregorio, Federico Perfetto, Anna Mazzeo, Calogero Falletta, Francesco Clemenza, Giuseppe Vita, Scipione Carerj, Giovanni Donato Aquar. Prevalence and diagnostic value of extra-left ventricle echocardiographic findings in transthyretin-related cardiac amyloidosis. Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis vol issue 2022 35465808 cardiac amyloidosis (ca) is cardiomyopathy with a hypertrophic phenotype characterised by diffuse deposition of anomalous fibrillar proteins in the extracellular matrix. 2022-04-25 2023-01-27 Not clear
Sandra Fawcett, Raida Al Kassas, Iain M Dykes, Alun Tl Hughes, Fawaz Ghali, Kehinde Ros. A time to heal: microRNA and circadian dynamics in cutaneous wound repair. Clinical science (London, England : 1979) vol 136 issue 8 2022 35445708 on the other hand, keloids and hypertrophic scars arise from overactive repair mechanisms that fail to cease in a timely fashion, leading to excessive production of extracellular matrix (ecm) components such as such as collagen. 2022-04-21 2023-01-27 Not clear
Hui Song Cui, Dong Hyun Kim, So Young Joo, Yoon Soo Cho, June-Bum Kim, Cheong Hoon Se. Exosomes derived from human hypertrophic scar fibroblasts induces smad and TAK1 signaling in normal dermal fibroblasts. Archives of biochemistry and biophysics vol issue 2022 35430216 post-burn hypertrophic scars are characterized by excessive accumulation of extracellular matrix secreted by fibroblasts. 2022-04-17 2023-01-27 human
Bo-Yu Yang, Zhi-Yuan Zhou, Shi-Yun Liu, Ming-Jun Shi, Xi-Jian Liu, Tian-Ming Cheng, Guo-Ying Deng, Ye Tian, Jian Song, Xuan-Hao L. Porous Se@SiO Frontiers in bioengineering and biotechnology vol 10 issue 2022 35387298 porous se@sio hypertrophic scarring, which is characterized by excessive extracellular matrix deposition and abnormal fibroblast homeostasis, is an undesirable outcome of dermal wound healing. 2022-04-07 2023-01-27 Not clear
Zhaojie Lyu, Yifeng Da, Hongkai Liu, Zhihao Wang, Yong Zhu, Jing Tia. Chsy1 deficiency reduces extracellular matrix productions and aggravates cartilage injury in osteoarthritis. Gene vol issue 2022 35390446 it was found that chsy1 deficiency resulted in a reduction of extracellular matrix production in chondrocytes and a promotion of endochondral osteogenesis, which was indicated by the decreased expression of early chondrocytes genes (col2a1, sox9), and the increased expression of cartilage hypertrophy genes (col10a1, runx2, mmp13, mmp3). 2022-04-07 2023-01-27 rat
Amy Larson, Christina J Codden, Gordon S Huggins, Hassan Rastegar, Frederick Y Chen, Barry J Maron, Ethan J Rowin, Martin S Maron, Michael T Chi. Altered intercellular communication and extracellular matrix signaling as a potential disease mechanism in human hypertrophic cardiomyopathy. Scientific reports vol 12 issue 1 2022 35338173 altered intercellular communication and extracellular matrix signaling as a potential disease mechanism in human hypertrophic cardiomyopathy. 2022-03-26 2023-01-27 human
Y B Meng, J Lei, H R Zhang, Z M Hao, P Y Bai, P Dua. [Clinical effects of in situ perforation of preserved split scar matrix in combination with scalp transplantation and vacuum sealing drainage in the treatment of hypertrophic scar in non-functional sites after burns]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns vol 38 issue 3 2022 35325970 [clinical effects of in situ perforation of preserved split scar matrix in combination with scalp transplantation and vacuum sealing drainage in the treatment of hypertrophic scar in non-functional sites after burns]. 2022-03-24 2023-01-27 Not clear
Alberto Aimo, Oriol Iborra-Egea, Nicola Martini, Carolina Galvez-Monton, Silvia Burchielli, Giorgia Panichella, Claudio Passino, Michele Emdin, Antoni Bayes-Geni. Cardiac protection by pirfenidone after myocardial infarction: a bioinformatic analysis. Scientific reports vol 12 issue 1 2022 35304529 we identified 6 causative motives of post-mi remodeling (cardiomyocyte cell death, impaired myocyte contractility, extracellular matrix remodeling and fibrosis, hypertrophy, renin-angiotensin-aldosterone system activation, and inflammation), 4 pirfenidone targets and 21 bioflags (indirect effectors). 2022-03-19 2023-01-27 Not clear
Ye Lu, Chengyuan Zhang, Shilin Jiang, Feng Yua. Anti-Dlx5 Retards the Progression of Osteoarthritis through Inhibiting Chondrocyte Hypertrophy and Apoptosis. Evidence-based complementary and alternative medicine : eCAM vol 2022 issue 2022 35280506 the results showed that administration of anti-dlx5 improved pathological changes of osteoarthritis cartilages, characterized by decreased chondrocyte proliferation, chondrocyte hypertrophy, and matrix damage. 2022-03-14 2023-01-27 Not clear
Kimberley C W Wang, Graham M Donovan, Sejal Saglani, Thais Mauad, Alan L James, John G Elliot, Peter B Nobl. Growth of the airway smooth muscle layer from late gestation to childhood is mediated initially by hypertrophy and subsequently hyperplasia. Respirology (Carlton, Vic.) vol issue 2022 35266251 this study characterized thickening of the asm layer from foetal life to childhood and elucidated the underlying mechanism in terms of hypertrophy, hyperplasia and extracellular matrix (ecm) deposition. 2022-03-10 2023-01-27 Not clear
Arijit Bhattacharjee, Dhirendra S Katt. A human osteoarthritis mimicking goat cartilage explant-based disease model for drug screening. ALTEX vol issue 2022 35258089 treatment with il1\xce\xb2 induced oa-like traits in goat cartilage explants and caused a shift in cartilage homeostasis towards enhanced catabolism, resulting in higher matrix degradation, overexpression of degradative and inflammatory mediators and chondrocyte hypertrophy. 2022-03-08 2023-01-27 human
Arijit Bhattacharjee, Dhirendra S Katt. A human osteoarthritis mimicking goat cartilage explant-based disease model for drug screening. ALTEX vol issue 2022 35258089 finally, we evaluated the translational relevance of the developed ex vivo oa model by comparing it with late-stage oa patient samples and observed a striking resemblance in terms of matrix degradation, expression of degradative enzymes, chondrocyte hypertrophy and inflammation. 2022-03-08 2023-01-27 human
Yingying Guo, Dan Li, Xian-Feng Cen, Hong-Liang Qiu, Yu-Lan Ma, Yi Liu, Si-Hui Huang, Li-Bo Liu, Man Xu, Qi-Zhu Tan. Diosmetin Protects against Cardiac Hypertrophy via p62/Keap1/Nrf2 Signaling Pathway. Oxidative medicine and cellular longevity vol 2022 issue 2022 35242278 an important pathophysiological consequence of pressure overload-induced cardiac hypertrophy is adverse cardiac remodeling, including structural changes in cardiomyocytes and extracellular matrix. 2022-03-04 2023-01-27 mouse
Yun Bai, Xiaoshan Gong, Rui Dong, Zhen Cao, Ce Dou, Chuan Liu, Jianmei Li, Fei Kang, Jingjin Dai, Chunrong Zhao, Zhansong Tian, Jiulin Tan, Qijie Dai, Shiwu Don. Long non-coding RNA HCAR promotes endochondral bone repair by upregulating VEGF and MMP13 in hypertrophic chondrocyte through sponging miR-15b-5p. Genes & diseases vol 9 issue 2 2022 35224160 here, we identified a lncrna, named hypertrophic chondrocyte angiogenesis-related lncrna (hcar), and proved it to promote the endochondral bone repair by upregulating the expression of matrix metallopeptidase 13 (mmp13) and vascular endothelial growth factor \xce\xb1 (vegfa) in hypertrophic chondrocytes. 2022-02-28 2023-01-27 Not clear