| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G A Cabral, F Marciano-Cabra. Cannabinoid receptors in microglia of the central nervous system: immune functional relevance. Journal of leukocyte biology. vol 78. issue 6. 2006-02-09. PMID:16204639. |
microglia, in addition to exhibiting phenotypic markers for macrophages, express cb1 and cb2 cannabinoid receptors. |
2006-02-09 |
2023-08-12 |
Not clear |
| G A Cabral, F Marciano-Cabra. Cannabinoid receptors in microglia of the central nervous system: immune functional relevance. Journal of leukocyte biology. vol 78. issue 6. 2006-02-09. PMID:16204639. |
the recognition that microglia express cannabinoid receptors and that their activation results in modulation of select cellular activities suggests that they may be amenable to therapeutic manipulation for ablating untoward inflammatory responses in the central nervous system. |
2006-02-09 |
2023-08-12 |
Not clear |
| Allyn Franklin, Nephi Stell. Arachidonylcyclopropylamide increases microglial cell migration through cannabinoid CB2 and abnormal-cannabidiol-sensitive receptors. European journal of pharmacology. vol 474. issue 2-3. 2004-04-23. PMID:12921861. |
arachidonylcyclopropylamide increases microglial cell migration through cannabinoid cb2 and abnormal-cannabidiol-sensitive receptors. |
2004-04-23 |
2023-08-12 |
mouse |
| Allyn Franklin, Nephi Stell. Arachidonylcyclopropylamide increases microglial cell migration through cannabinoid CB2 and abnormal-cannabidiol-sensitive receptors. European journal of pharmacology. vol 474. issue 2-3. 2004-04-23. PMID:12921861. |
to determine if cannabinoid cb(1) receptors expressed by microglial cells modulate their migration, we assessed whether arachidonylcyclopropylamide (acpa, an agonist shown to selectively activate cb(1) receptors) affects the migration of bv-2 cells, a mouse microglial cell line. |
2004-04-23 |
2023-08-12 |
mouse |
| Allyn Franklin, Nephi Stell. Arachidonylcyclopropylamide increases microglial cell migration through cannabinoid CB2 and abnormal-cannabidiol-sensitive receptors. European journal of pharmacology. vol 474. issue 2-3. 2004-04-23. PMID:12921861. |
our results suggest that cannabinoid cb(2) receptors and abn-cbd receptors, rather than cannabinoid cb(1) receptors, regulate microglial cell migration, and that acpa is a broad cannabinoid receptor agonist. |
2004-04-23 |
2023-08-12 |
mouse |
| Erica J Carrier, Christopher S Kearn, Andrew J Barkmeier, Nicole M Breese, Wenqi Yang, Kasem Nithipatikom, Sandra L Pfister, William B Campbell, Cecilia J Hillar. Cultured rat microglial cells synthesize the endocannabinoid 2-arachidonylglycerol, which increases proliferation via a CB2 receptor-dependent mechanism. Molecular pharmacology. vol 65. issue 4. 2004-04-21. PMID:15044630. |
because peripheral macrophages are capable of producing endocannabinoids, we have examined endocannabinoid production in a macrophage-colony stimulating factor (m-csf)-dependent rat microglial cell line (rtmgl1) using reversed phase high-pressure liquid chromatography and liquid chromatography-mass spectroscopy. |
2004-04-21 |
2023-08-12 |
rat |
| Celine Gongora, Stacey Hose, Terrence P O'Brien, Debasish Sinh. Downregulation of class II transactivator (CIITA) expression by synthetic cannabinoid CP55,940. Immunology letters. vol 91. issue 1. 2004-03-30. PMID:14757364. |
cannabinoid receptors are known to be expressed in microglia; however, their involvement in specific aspects of microglial immune function has not been demonstrated. |
2004-03-30 |
2023-08-12 |
Not clear |
| P K Peterson, G Gekker, S Hu, G Cabral, J R Lokensgar. Cannabinoids and morphine differentially affect HIV-1 expression in CD4(+) lymphocyte and microglial cell cultures. Journal of neuroimmunology. vol 147. issue 1-2. 2004-03-15. PMID:14741442. |
cannabinoids and morphine differentially affect hiv-1 expression in cd4(+) lymphocyte and microglial cell cultures. |
2004-03-15 |
2023-08-12 |
Not clear |
| P K Peterson, G Gekker, S Hu, G Cabral, J R Lokensgar. Cannabinoids and morphine differentially affect HIV-1 expression in CD4(+) lymphocyte and microglial cell cultures. Journal of neuroimmunology. vol 147. issue 1-2. 2004-03-15. PMID:14741442. |
the synthetic cannabinoid win 55,212-2 was found to potently inhibit hiv-1 expression in a concentration- and time-dependent manner in cd4(+) lymphocyte and microglial cell cultures. |
2004-03-15 |
2023-08-12 |
Not clear |
| Cristina Benito, Estefanía Núñez, Rosa M Tolón, Erica J Carrier, Alberto Rábano, Cecilia J Hillard, Julián Romer. Cannabinoid CB2 receptors and fatty acid amide hydrolase are selectively overexpressed in neuritic plaque-associated glia in Alzheimer's disease brains. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 35. 2003-12-23. PMID:14657172. |
our results show that both fatty acid amide hydrolase and cannabinoid cb2 receptors are abundantly and selectively expressed in neuritic plaque-associated astrocytes and microglia, respectively, whereas the expression of cb1 receptors remains unchanged. |
2003-12-23 |
2023-08-12 |
human |
| Lisa Walter, Nephi Stell. Endothelin-1 increases 2-arachidonoyl glycerol (2-AG) production in astrocytes. Glia. vol 44. issue 1. 2003-12-15. PMID:12951660. |
immunocytochemistry showed that although cultured mouse neurons and microglia express cannabinoid receptors, cultured astrocytes do not. |
2003-12-15 |
2023-08-12 |
mouse |
| Lisa Walter, Nephi Stell. Endothelin-1 increases 2-arachidonoyl glycerol (2-AG) production in astrocytes. Glia. vol 44. issue 1. 2003-12-15. PMID:12951660. |
the data suggest that endothelin-1 modulates 2-ag production in astrocytes and that this endocannabinoid may participate in paracrine signaling toward neurons and microglia. |
2003-12-15 |
2023-08-12 |
mouse |
| Fabrizio Facchinetti, Elda Del Giudice, Sara Furegato, Marzla Passarotto, Alberta Leo. Cannabinoids ablate release of TNFalpha in rat microglial cells stimulated with lypopolysaccharide. Glia. vol 41. issue 2. 2003-04-02. PMID:12509806. |
as cannabinoids have been reported to exert anti-inflammatory and neuroprotective actions in the brain, we here examined the effect of both synthetic and endogenous cannabinoids on tnfalpha release elicited by bacterial endotoxin lypopolysaccharide (lps) in cultured microglia. |
2003-04-02 |
2023-08-12 |
rat |
| Lisa Walter, Allyn Franklin, Anke Witting, Christian Wade, Yiheng Xie, George Kunos, Ken Mackie, Nephi Stell. Nonpsychotropic cannabinoid receptors regulate microglial cell migration. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 4. 2003-03-24. PMID:12598628. |
nonpsychotropic cannabinoid receptors regulate microglial cell migration. |
2003-03-24 |
2023-08-12 |
Not clear |
| Lisa Walter, Allyn Franklin, Anke Witting, Christian Wade, Yiheng Xie, George Kunos, Ken Mackie, Nephi Stell. Nonpsychotropic cannabinoid receptors regulate microglial cell migration. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 4. 2003-03-24. PMID:12598628. |
our study identifies a cannabinoid signaling system regulating microglial cell migration. |
2003-03-24 |
2023-08-12 |
Not clear |
| G B Stefano, Y Liu, M S Goligorsk. Cannabinoid receptors are coupled to nitric oxide release in invertebrate immunocytes, microglia, and human monocytes. The Journal of biological chemistry. vol 271. issue 32. 1996-09-16. PMID:8702604. |
cannabinoid receptors are coupled to nitric oxide release in invertebrate immunocytes, microglia, and human monocytes. |
1996-09-16 |
2023-08-12 |
human |
| G B Stefano, Y Liu, M S Goligorsk. Cannabinoid receptors are coupled to nitric oxide release in invertebrate immunocytes, microglia, and human monocytes. The Journal of biological chemistry. vol 271. issue 32. 1996-09-16. PMID:8702604. |
the present study demonstrates that stereoselective binding sites for anandamide, a naturally occurring cannabinoid substance, can be found in invertebrate immunocytes and microglia. |
1996-09-16 |
2023-08-12 |
human |