| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R A Padua, T Yamamoto, D Fyda, M A Sawchuk, J D Geiger, J I Nag. Autoradiographic analysis of [3H]Ryanodine binding sites in rat brain: regional distribution and the effects of lesions on sites in the hippocampus. Journal of chemical neuroanatomy. vol 5. issue 1. 1992-07-23. PMID:1605914. |
in experimental animals, intracerebral injections of kainic acid caused neuronal degeneration and a near total depletion of [3h]ryanodine binding sites in the dentate gyrus and in fields ca1, ca2 and ca3 of the hippocampus. |
1992-07-23 |
2023-08-11 |
rat |
| A Mitani, Y Andou, K Kataok. Selective vulnerability of hippocampal CA1 neurons cannot be explained in terms of an increase in glutamate concentration during ischemia in the gerbil: brain microdialysis study. Neuroscience. vol 48. issue 2. 1992-07-16. PMID:1351267. |
in the present study, we measured the levels of released glutamate during ischemia in field ca1 and field ca3, separately, and evaluated whether there are subregional differences in the concentration of released glutamate which could be a satisfactory explanation for the selective vulnerability of hippocampal neurons to ischemia. |
1992-07-16 |
2023-08-11 |
Not clear |
| A Mitani, Y Andou, K Kataok. Selective vulnerability of hippocampal CA1 neurons cannot be explained in terms of an increase in glutamate concentration during ischemia in the gerbil: brain microdialysis study. Neuroscience. vol 48. issue 2. 1992-07-16. PMID:1351267. |
extracellular glutamate levels were significantly increased during ischemia in both field ca1 and field ca3. |
1992-07-16 |
2023-08-11 |
Not clear |
| A Mitani, Y Andou, K Kataok. Selective vulnerability of hippocampal CA1 neurons cannot be explained in terms of an increase in glutamate concentration during ischemia in the gerbil: brain microdialysis study. Neuroscience. vol 48. issue 2. 1992-07-16. PMID:1351267. |
no significant differences were detected in the time-course of change in glutamate release and the levels of glutamate between field ca1 and field ca3. |
1992-07-16 |
2023-08-11 |
Not clear |
| M Nakamura, M Araki, K Oguro, T Masuzaw. Differential distribution of 68 Kd and 200 Kd neurofilament proteins in the gerbil hippocampus and their early distributional changes following transient forebrain ischemia. Experimental brain research. vol 89. issue 1. 1992-07-16. PMID:1601102. |
in the normal hippocampus, nf68-like immunoreactivity (nf68-li) was densely distributed in nerve processes in ca2, ca3 and the hilus of the dentate gyrus but was less intense in ca1. |
1992-07-16 |
2023-08-11 |
Not clear |
| M Nakamura, M Araki, K Oguro, T Masuzaw. Differential distribution of 68 Kd and 200 Kd neurofilament proteins in the gerbil hippocampus and their early distributional changes following transient forebrain ischemia. Experimental brain research. vol 89. issue 1. 1992-07-16. PMID:1601102. |
in contrast, processes with nf200-li appeared to be evenly distributed in ca1, ca2, ca3 and the dentate gyrus. |
1992-07-16 |
2023-08-11 |
Not clear |
| M Nakamura, M Araki, K Oguro, T Masuzaw. Differential distribution of 68 Kd and 200 Kd neurofilament proteins in the gerbil hippocampus and their early distributional changes following transient forebrain ischemia. Experimental brain research. vol 89. issue 1. 1992-07-16. PMID:1601102. |
four days after ischemia, when neuronal death of ca1 pyramidal cells had occurred, processes in ca1, particularly 68 kd components, showed marked decreases in number and staining intensity, although processes in most layers of ca2, ca3 and the dentate gyrus appeared to be stained similarly to normal brain. |
1992-07-16 |
2023-08-11 |
Not clear |
| C Moncada, B Arvin, E Le Peillet, B S Meldru. Non-NMDA antagonists protect against kainate more than AMPA toxicity in the rat hippocampus. Neuroscience letters. vol 133. issue 2. 1992-06-26. PMID:1816508. |
single focal injection of the excitatory amino acids (eaas) kainic acid (ka, 1.1 nmol/microliters) and (s)-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (s)-ampa, 6 nmol/microliters) into rat dorsal hippocampus resulted in widespread neurodegeneration with 90-100% loss of hippocampal pyramidal cells in ca1, ca2, ca3 and ca4 subfields, and 50-70% loss of dentate granule (dg) cells. |
1992-06-26 |
2023-08-11 |
rat |
| C Moncada, B Arvin, E Le Peillet, B S Meldru. Non-NMDA antagonists protect against kainate more than AMPA toxicity in the rat hippocampus. Neuroscience letters. vol 133. issue 2. 1992-06-26. PMID:1816508. |
focal injection of nmda (30 nmol/microliters) under the same conditions resulted in 70-90% loss of ca1 cells with less damage in ca2, ca3, ca4 and dg cells (30-50%, 10-30%, and 30-50%, respectively). |
1992-06-26 |
2023-08-11 |
rat |
| C Moncada, B Arvin, E Le Peillet, B S Meldru. Non-NMDA antagonists protect against kainate more than AMPA toxicity in the rat hippocampus. Neuroscience letters. vol 133. issue 2. 1992-06-26. PMID:1816508. |
infusion (30 mg/kg/3h), protected against ka toxicity in ca1, ca2 and dg cells, with no protection in ca3 and ca4. |
1992-06-26 |
2023-08-11 |
rat |
| D Paré, M deCurtis, R Lliná. Role of the hippocampal-entorhinal loop in temporal lobe epilepsy: extra- and intracellular study in the isolated guinea pig brain in vitro. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 12. issue 5. 1992-06-05. PMID:1578275. |
two patterns of eds were distinguished by performing simultaneous field potential recordings along the dentate gyrus (dg), ec, ca1, and ca3. |
1992-06-05 |
2023-08-11 |
human |
| D Paré, M deCurtis, R Lliná. Role of the hippocampal-entorhinal loop in temporal lobe epilepsy: extra- and intracellular study in the isolated guinea pig brain in vitro. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 12. issue 5. 1992-06-05. PMID:1578275. |
thereafter, population spikes occurred sequentially in the ca1 region, ec, dg, and back to the ca3 region. |
1992-06-05 |
2023-08-11 |
human |
| D Johnston, S Williams, D Jaffe, R Gra. NMDA-receptor-independent long-term potentiation. Annual review of physiology. vol 54. 1992-05-12. PMID:1314043. |
at the hippocampal ca3 mf synapse, activation of voltage-gated ca2+ channels has been proposed as a trigger for ltp induction, and this may also be the case for certain types of ltp at the sc synapse in ca1 (25, 40). |
1992-05-12 |
2023-08-11 |
Not clear |
| M Morioka, K Fukunaga, S Yasugawa, S Nagahiro, Y Ushio, E Miyamot. Regional and temporal alterations in Ca2+/calmodulin-dependent protein kinase II and calcineurin in the hippocampus of rat brain after transient forebrain ischemia. Journal of neurochemistry. vol 58. issue 5. 1992-05-11. PMID:1313854. |
immunoreactivity and enzyme activity of cam kinase ii decreased in regions ca1 and ca3, and in the dentate gyrus, of the hippocampus early (6-12 h) after ischemia, but the decrease in immunoreactivity gradually recovered over time, except in the ca1 region. |
1992-05-11 |
2023-08-11 |
rat |
| J R Seckl, K L Dickson, C Yates, G Fin. Distribution of glucocorticoid and mineralocorticoid receptor messenger RNA expression in human postmortem hippocampus. Brain research. vol 561. issue 2. 1992-04-24. PMID:1666329. |
gr mrna was highly expressed in dentate gyrus, ca3 and ca4, but levels were significantly lower in ca1 and ca2. |
1992-04-24 |
2023-08-11 |
human |
| J R Seckl, K L Dickson, C Yates, G Fin. Distribution of glucocorticoid and mineralocorticoid receptor messenger RNA expression in human postmortem hippocampus. Brain research. vol 561. issue 2. 1992-04-24. PMID:1666329. |
mr mrna was also very highly expressed in hippocampus, with significantly higher levels in dentate gyrus and ca2, ca3 and ca4 than ca1. |
1992-04-24 |
2023-08-11 |
human |
| K Kitagawa, M Matsumoto, K Kuwabara, M Tagaya, T Ohtsuki, R Hata, H Ueda, N Handa, K Kimura, T Kamad. 'Ischemic tolerance' phenomenon detected in various brain regions. Brain research. vol 561. issue 2. 1992-04-24. PMID:1802339. |
single 10-min ischemia consistently caused neuronal damage in the hippocampal ca1, ca2, ca3 and ca4, layer iii/iv of the cerebral cortex, dorsolateral part of the caudoputamen and ventrolateral part of the thalamus. |
1992-04-24 |
2023-08-11 |
Not clear |
| D T Chalmers, S J Watso. Comparative anatomical distribution of 5-HT1A receptor mRNA and 5-HT1A binding in rat brain--a combined in situ hybridisation/in vitro receptor autoradiographic study. Brain research. vol 561. issue 1. 1992-04-16. PMID:1797349. |
high levels of both 5-ht1a mrna and 5-ht1a receptors were evident in the hippocampal formation (ca1, ca3, dentate gyrus), entorhinal cortex, and raphe nuclei and lower levels in neocortex and thalamus. |
1992-04-16 |
2023-08-11 |
rat |
| N Lindefors, P Ernfors, T Falkenberg, H Persso. Septal cholinergic afferents regulate expression of brain-derived neurotrophic factor and beta-nerve growth factor mRNA in rat hippocampus. Experimental brain research. vol 88. issue 1. 1992-04-03. PMID:1541364. |
both bdnf and ngf mrna levels increased more than 4-fold in the granule layer of the dentate gyrus and for bdnf mrna also in the pyramidal cells of ca1, while the levels of bdnf mrna in ca3 increased 2-fold. |
1992-04-03 |
2023-08-11 |
rat |
| G Lallement, P Carpentier, A Collet, I Pernot-Marino, D Baubichon, G Blanche. Effects of soman-induced seizures on different extracellular amino acid levels and on glutamate uptake in rat hippocampus. Brain research. vol 563. issue 1-2. 1992-03-23. PMID:1786536. |
extracellular amino acid levels in ca3 and ca1 fields of rat hippocampus, an area highly sensitive to seizures, were determined by intracranial microdialysis during seizures induced by systemic administration of soman (o-1,2,2-trimethylpropyl methylphosphonofluoridate), a potent inhibitor of acetylcholinesterase. |
1992-03-23 |
2023-08-11 |
rat |