Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
C L Meier, A Obenaus, F E Dude. Persistent hyperexcitability in isolated hippocampal CA1 of kainate-lesioned rats. Journal of neurophysiology. vol 68. issue 6. 1993-03-03. PMID:1491262. |
subcutaneous kainate injection in rats evoked acute seizures and led to cell loss in the hilus and areas ca1 and ca3, which resembled the pattern of hippocampal sclerosis often associated with temporal lobe epilepsy in humans. |
1993-03-03 |
2023-08-11 |
rat |
C E Ribak, L Seress, C Lerant. Electron microscopic immunocytochemical study of the distribution of parvalbumin-containing neurons and axon terminals in the primate dentate gyrus and Ammon's horn. The Journal of comparative neurology. vol 327. issue 2. 1993-03-02. PMID:8425946. |
both semithin sections and electron microscopic preparations indicated that more pv-positive axon terminals formed symmetric axosomatic synapses with pyramidal cells in ca2 than in ca1 and ca3. |
1993-03-02 |
2023-08-12 |
monkey |
J Walden, H Grunze, D Bingmann, Z Liu, R Düsin. Calcium antagonistic effects of carbamazepine as a mechanism of action in neuropsychiatric disorders: studies in calcium dependent model epilepsies. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 2. issue 4. 1993-03-01. PMID:1490097. |
in ca3 and ca1 areas of hippocampal slice preparations of guinea pigs cbz reduced paroxysmal depolarizations and extracellular field potentials (efp) in a typical time and concentration dependent manner as it is known from calcium antagonists. |
1993-03-01 |
2023-08-11 |
Not clear |
B R Finsen, M B Jørgensen, N H Diemer, J Zimme. Microglial MHC antigen expression after ischemic and kainic acid lesions of the adult rat hippocampus. Glia. vol 7. issue 1. 1993-02-23. PMID:8423061. |
subpopulations of microglial cells also expressed class ii mhc antigen and leukocyte common antigen (lca) in relation to (1) degenerating nerve cell bodies in the dentate hilus and the ca1 and ca3 pyramidal cell layers, (2) postischemic degeneration of dendrites in the stratum radiatum of ca1, and (3) combined dendritic and axonal degeneration in the stratum radiatum of the ka-lesioned ca3. |
1993-02-23 |
2023-08-12 |
rat |
R F Genovese, J M Petras, F C Tortell. Evaluation of transient forebrain ischemia induced by four vessel occlusion using schedule-controlled behavior. Physiology & behavior. vol 52. issue 5. 1993-02-18. PMID:1484834. |
severe damage in the ca1, ca2, and ca3 formations was observed in a single rat, and that rat also showed the greatest degree of response disruption. |
1993-02-18 |
2023-08-11 |
rat |
P Jonas, B Sakman. Glutamate receptor channels in isolated patches from CA1 and CA3 pyramidal cells of rat hippocampal slices. The Journal of physiology. vol 455. 1993-02-17. PMID:1282929. |
currents activated by glutamate receptor (glur) agonists were recorded from outside-out patches isolated from the soma of visually identified pyramidal neurones of the ca3 and ca1 region of rat hippocampal slices. |
1993-02-17 |
2023-08-11 |
rat |
Y Watanabe, H Saito, K Ab. Effects of glycine and structurally related amino acids on generation of long-term potentiation in rat hippocampal slices. European journal of pharmacology. vol 223. issue 2-3. 1993-02-09. PMID:1478265. |
the effects of glycine and structurally related amino acids, serine, alanine and valine, on generation of long-term potentiation (ltp) of evoked potentials were investigated in the ca1, ca3 and dentate regions of rat hippocampal slices. |
1993-02-09 |
2023-08-11 |
rat |
Y Watanabe, H Saito, K Ab. Effects of glycine and structurally related amino acids on generation of long-term potentiation in rat hippocampal slices. European journal of pharmacology. vol 223. issue 2-3. 1993-02-09. PMID:1478265. |
these results suggest that exogenous glycine can facilitate the generation of ltp in the ca1 region and in the dentate gyrus but not in the ca3 region. |
1993-02-09 |
2023-08-11 |
rat |
G Lallement, P Carpentier, A Collet, D Baubichon, I Pernot-Marino, G Blanche. Extracellular acetylcholine changes in rat limbic structures during soman-induced seizures. Neurotoxicology. vol 13. issue 3. 1993-02-03. PMID:1475060. |
extracellular acetylcholine (ach) levels were determined, by intracranial microdialysis, in medial septum, amygdala and hippocampus (ca1, ca3, dentate gyrus) of rats during seizures induced by systemic administration of soman (pinacolyl methylphosphonofluoridate), a potent inhibitor of acetylcholinesterase (ache). |
1993-02-03 |
2023-08-11 |
rat |
K J Sass, A Sass, M Westerveld, T Lencz, R A Novelly, J H Kim, D D Spence. Specificity in the correlation of verbal memory and hippocampal neuron loss: dissociation of memory, language, and verbal intellectual ability. Journal of clinical and experimental neuropsychology. vol 14. issue 5. 1993-02-01. PMID:1474137. |
after surgical removal of the mesial temporal lobe structures, two blinded observers established volumetric cell densities for hippocampal subfields ca1, ca2, ca3, the hilar area, and the granule cell layer of area dentata. |
1993-02-01 |
2023-08-11 |
Not clear |
A Yoshino, D A Hovda, Y Katayama, T Kawamata, D P Becke. Hippocampal CA3 lesion prevents postconcussive metabolic dysfunction in CA1. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 12. issue 6. 1992-11-25. PMID:1356995. |
to determine if endogenous glutamate innervation to the ca1 region of the hippocampus can provide an anatomical basis for this proposed mechanism, it was removed by kainic-acid-induced destruction of ca3, and the effect on ca1 metabolism following concussive injury was studied. |
1992-11-25 |
2023-08-11 |
rat |
P Dauch, Y Masuo, J P Vincent, F Checle. Endopeptidase 24-16 in murines: tissue distribution, cerebral regionalization, and ontogeny. Journal of neurochemistry. vol 59. issue 5. 1992-11-20. PMID:1402928. |
endopeptidase 24-16 appeared in high concentrations in the olfactory bulb and tubercule, cingulate cortex, medial striatum, and globus pallidus, and was particularly weak in the ca1, ca2, and ca3 parts of the hippocampal formation and in the cerebellum. |
1992-11-20 |
2023-08-11 |
mouse |
S G Beck, K C Choi, T J Lis. Comparison of 5-hydroxytryptamine1A-mediated hyperpolarization in CA1 and CA3 hippocampal pyramidal cells. The Journal of pharmacology and experimental therapeutics. vol 263. issue 1. 1992-11-20. PMID:1403796. |
5-hydroxytryptamine (5-ht) hyperpolarizes hippocampal pyramidal cells in both areas ca1 and ca3 through an increase in potassium conductance. |
1992-11-20 |
2023-08-11 |
Not clear |
S G Beck, K C Choi, T J Lis. Comparison of 5-hydroxytryptamine1A-mediated hyperpolarization in CA1 and CA3 hippocampal pyramidal cells. The Journal of pharmacology and experimental therapeutics. vol 263. issue 1. 1992-11-20. PMID:1403796. |
the receptor mediating the hyperpolarization in ca1 has been characterized as the 5-ht1a receptor, but has not been identified in area ca3. |
1992-11-20 |
2023-08-11 |
Not clear |
S G Beck, K C Choi, T J Lis. Comparison of 5-hydroxytryptamine1A-mediated hyperpolarization in CA1 and CA3 hippocampal pyramidal cells. The Journal of pharmacology and experimental therapeutics. vol 263. issue 1. 1992-11-20. PMID:1403796. |
the 5-ht1 agonist 5-carboxyamidotryptamine and 5-ht were full agonists and the 5-ht1a-selective ligand 8-hydroxydipropyl-aminotetralin hydrobromide was a partial agonist in both ca3 and ca1. |
1992-11-20 |
2023-08-11 |
Not clear |
S G Beck, K C Choi, T J Lis. Comparison of 5-hydroxytryptamine1A-mediated hyperpolarization in CA1 and CA3 hippocampal pyramidal cells. The Journal of pharmacology and experimental therapeutics. vol 263. issue 1. 1992-11-20. PMID:1403796. |
the agonists were a half-log unit less potent and the maximum response elicited by 5-carboxyamidotryptamine and 5-ht was greater in area ca3 than in area ca1. |
1992-11-20 |
2023-08-11 |
Not clear |
S G Beck, K C Choi, T J Lis. Comparison of 5-hydroxytryptamine1A-mediated hyperpolarization in CA1 and CA3 hippocampal pyramidal cells. The Journal of pharmacology and experimental therapeutics. vol 263. issue 1. 1992-11-20. PMID:1403796. |
the selective 5-ht1a antagonist bmy 7378 and the 5-ht1a/2 antagonist spiperone were competitive in area ca1, but insurmountable in area ca3. |
1992-11-20 |
2023-08-11 |
Not clear |
S G Beck, K C Choi, T J Lis. Comparison of 5-hydroxytryptamine1A-mediated hyperpolarization in CA1 and CA3 hippocampal pyramidal cells. The Journal of pharmacology and experimental therapeutics. vol 263. issue 1. 1992-11-20. PMID:1403796. |
based on these results, we conclude that the hyperpolarization elicited by 5-ht in areas ca1 and ca3 is mediated by the 5-ht1a receptor. |
1992-11-20 |
2023-08-11 |
Not clear |
A Malgaroli, R Malinow, H Schulman, R W Tsie. Persistent signalling and changes in presynaptic function in long-term potentiation. Ciba Foundation symposium. vol 164. 1992-11-19. PMID:1327679. |
at the synapse between hippocampal ca3 and ca1 neurons ltp is induced by a ca2+ influx through glutamate receptors of the nmda (n-methyl-d-aspartate) type (see collingridge et al 1992, this volume). |
1992-11-19 |
2023-08-11 |
Not clear |
N Amlaiky, S Ramboz, U Boschert, J L Plassat, R He. Isolation of a mouse "5HT1E-like" serotonin receptor expressed predominantly in hippocampus. The Journal of biological chemistry. vol 267. issue 28. 1992-11-16. PMID:1328180. |
in situ hybridization experiments revealed that the 5ht1e beta transcripts were detected only in the ca1, ca2, and ca3 layers of the hippocampus. |
1992-11-16 |
2023-08-11 |
mouse |