| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J J Vornov, R C Tasker, J T Coyl. Direct observation of the agonist-specific regional vulnerability to glutamate, NMDA, and kainate neurotoxicity in organotypic hippocampal cultures. Experimental neurology. vol 114. issue 1. 1991-10-30. PMID:1717307. |
glutamate (1 mm) caused a delayed, progressive pattern of staining that began in ca1 (2 to 4 h after exposure), then extended to include ca3 and finally the dentate gyrus over the next 24 h. release of ldh activity into the media was slower and less sensitive than propidium staining. |
1991-10-30 |
2023-08-11 |
Not clear |
| C Leranth, C E Riba. Calcium-binding proteins are concentrated in the CA2 field of the monkey hippocampus: a possible key to this region's resistance to epileptic damage. Experimental brain research. vol 85. issue 1. 1991-10-10. PMID:1884753. |
the density and intensity of immunoreactivity for both of these calcium-binding proteins was greatest in ca2 as compared to ca1 and ca3. |
1991-10-10 |
2023-08-11 |
rat |
| D Leifer, D G Cole, N W Kowal. Neuropathologic asymmetries in the brain of a patient with a unilateral status epilepticus. Journal of the neurological sciences. vol 103. issue 2. 1991-09-30. PMID:1715386. |
autopsy study of a patient who died after an episode of prolonged unilateral status epilepticus revealed neuronal loss in the hippocampus on the epileptic side, with gliosis confined to the ca1 and ca3 fields. |
1991-09-30 |
2023-08-11 |
human |
| G Debonnel, M Weiss, C de Montign. Neurotoxic effect of domoic acid: mediation by kainate receptor electrophysiological studies in the rat. Canada diseases weekly report = Rapport hebdomadaire des maladies au Canada. vol 16 Suppl 1E. 1991-09-19. PMID:1983213. |
the present in vivo electrophysiological studies, using unitary extracellular recordings obtained from pyramidal neurons of the ca1 and of the ca3 regions of the rat dorsal hippocampus, were undertaken to study the effect of kainic acid and domoic acid applied by microiontophoresis and compare their potencies to that of agonists of the 2 other subtypes of glutamatergic receptors or neuropeptides. |
1991-09-19 |
2023-08-11 |
rat |
| C Grillo, S Vallee, G Piroli, J A Angulo, B S McEwen, A F De Nicol. Effects of deoxycorticosterone treatment on beta-subunit mRNA for (Na + K)ATPase in brain regions determined by in situ hybridization. Cellular and molecular neurobiology. vol 11. issue 3. 1991-09-16. PMID:1651164. |
doc treatment did not change the number of silver grains/cell deposited in cells from ca1, ca2, ca3, and ca4 hippocampal subfields, dentate gyrus, cerebral cortex, medial preoptic area (poa), substantia nigra, and periventricular gray matter. |
1991-09-16 |
2023-08-11 |
rat |
| M Parmentier, E Passage, G Vassart, M G Matte. The human calbindin D28k (CALB1) and calretinin (CALB2) genes are located at 8q21.3----q22.1 and 16q22----q23, respectively, suggesting a common duplication with the carbonic anhydrase isozyme loci. Cytogenetics and cell genetics. vol 57. issue 1. 1991-08-29. PMID:1906795. |
these localizations match the chromosomal regions where the carbonic anhydrase isozyme gene cluster (ca1, ca2, ca3) and the related gene ca7 have been described, respectively. |
1991-08-29 |
2023-08-11 |
human |
| M P Witter, D G Amara. Entorhinal cortex of the monkey: V. Projections to the dentate gyrus, hippocampus, and subicular complex. The Journal of comparative neurology. vol 307. issue 3. 1991-08-28. PMID:1713237. |
the entorhinal cortex gave rise to projections that terminated in the subiculum, in the ca1, ca2, and ca3 fields of the hippocampus, and in the dentate gyrus. |
1991-08-28 |
2023-08-11 |
rat |
| M P Witter, D G Amara. Entorhinal cortex of the monkey: V. Projections to the dentate gyrus, hippocampus, and subicular complex. The Journal of comparative neurology. vol 307. issue 3. 1991-08-28. PMID:1713237. |
projections to the dentate gyrus, and fields ca3 and ca2 of the hippocampus, originated preferentially in layers ii and vi of the entorhinal cortex whereas projections to ca1 and to the subiculum originated mainly in layers iii and v. anterograde tracing experiments demonstrated that all regions of the entorhinal cortex project to the outer two-thirds of the molecular layer of the dentate gyrus and to much of the radial extent of the stratum lacunosum-moleculare of ca3 and ca2. |
1991-08-28 |
2023-08-11 |
rat |
| Z Oláh, S Komoly, N Nagashima, F Joó, U R Rapp, W B Anderso. Cerebral ischemia induces transient intracellular redistribution and intranuclear translocation of the raf proto-oncogene product in hippocampal pyramidal cells. Experimental brain research. vol 84. issue 2. 1991-08-13. PMID:2065747. |
non-occluded hemisphere) neurons of ca1 and ca3 subfields 4 days after the ischemic insult indicating a possible transsynaptic increase in the amount of raf protein along with redistribution. |
1991-08-13 |
2023-08-11 |
Not clear |
| O Bengoechea, L M Gonzal. Effects of alcoholization on the rat hippocampus. Neuroscience letters. vol 123. issue 1. 1991-08-02. PMID:2062446. |
the neuron loss in group a, with respect to group c was: highly significant (p less than 0.001) for ca2; very significant (p less than 0.01) for ca3 and ca4; in ca1 and gd the reduction was not significant. |
1991-08-02 |
2023-08-11 |
rat |
| N Hori, N Doi, S Miyahara, Y Shinoda, D O Carpente. Appearance of NMDA receptors triggered by anoxia independent of voltage in vivo and in vitro. Experimental neurology. vol 112. issue 3. 1991-06-17. PMID:1827626. |
after anoxic damage to the intact animal, neurons in both ca1 and ca3 show abnormal bursting discharges in response to synaptic activation for several days, and then the response in ca1 decreases in amplitude and finally the area become unexcitable. |
1991-06-17 |
2023-08-11 |
rat |
| N Hori, N Doi, S Miyahara, Y Shinoda, D O Carpente. Appearance of NMDA receptors triggered by anoxia independent of voltage in vivo and in vitro. Experimental neurology. vol 112. issue 3. 1991-06-17. PMID:1827626. |
however, a period of hyperexcitability and bursting follows and electrical excitability is lost in ca1 but not ca3 neurons after about 90 min. |
1991-06-17 |
2023-08-11 |
rat |
| A Mitani, F Kadoya, Y Nakamura, K Kataok. Visualization of hypoxia-induced glutamate release in gerbil hippocampal slice. Neuroscience letters. vol 122. issue 2. 1991-06-07. PMID:2027517. |
the hypoxia-induced release of glutamate was gradually increased throughout the slice: no significant difference was detected among ca1 region, ca3 region and the dentate gyrus. |
1991-06-07 |
2023-08-11 |
Not clear |
| M Lerner-Natoli, G Rondouin, M Belaidi, M Baldy-Moulinier, J M Kamenk. N-[1-(2-thienyl)cyclohexyl]-piperidine (TCP) does not block kainic acid-induced status epilepticus but reduces secondary hippocampal damage. Neuroscience letters. vol 122. issue 2. 1991-06-07. PMID:2027518. |
distant damage, localized in the ca3 and ca1 areas, was observed in the hippocampus of rats as a consequence of status epilepticus (se) induced by the injection of 2.5 nmol of kainic acid (ka) into the amygdala. |
1991-06-07 |
2023-08-11 |
rat |
| D Jaarsma, J B Sebens, J Kor. Reduction of adenosine A1-receptors in the perforant pathway terminal zone in Alzheimer hippocampus. Neuroscience letters. vol 121. issue 1-2. 1991-05-29. PMID:1850501. |
the ca1 and the ca3, in spite of a pronounced cellular pathology and reduced n-methyl-d-aspartate (nmda) receptor densities, assessed as strychnine insensitive [3h]glycine autoradiography. |
1991-05-29 |
2023-08-11 |
rat |
| W Stummer, K Weber, L Schürer, A Baethmann, O Kempsk. Electrical impedance, rCBF, survival and histology in Mongolian gerbils with forebrain ischaemia. Acta neurochirurgica. Supplementum. vol 51. 1991-05-24. PMID:2089890. |
neuronal loss was found in all animals in the hippocampus (ca1, ca2, ca3 and ca4), and was most pronounced in the ca1 sector. |
1991-05-24 |
2023-08-11 |
Not clear |
| M F Gonzalez, D Lowenstein, S Fernyak, K Hisanaga, R Simon, F R Shar. Induction of heat shock protein 72-like immunoreactivity in the hippocampal formation following transient global ischemia. Brain research bulletin. vol 26. issue 2. 1991-05-16. PMID:2012984. |
it is proposed that (a) the induction of hsp72 in hippocampal sectors correlates with their vulnerability to global ischemia (ca1 greater than hilus greater than ca3 greater than dentate gyrus); (b) the induction of hsp72 in hippocampal cells correlates with their vulnerability to global ischemia in that mild ischemia induced hsp72 only in neurons, moderate ischemia in neurons and glia, and severe ischemia only in capillary endothelial cells; (c) the failure to induce hsp72 in hippocampal neurons in 2 cases of 10 min ischemia may be related to severe injury causing disruption of protein synthesis in these cells. |
1991-05-16 |
2023-08-11 |
rat |
| G J Lees, A Lehmann, M Sandberg, A Hamberge. The neurotoxicity of ouabain, a sodium-potassium ATPase inhibitor, in the rat hippocampus. Neuroscience letters. vol 120. issue 2. 1991-04-09. PMID:1705675. |
the neuronal perikaryal death produced in the subicular, ca1 and ca2 regions was only partially decreased by intraperitoneal injections of the anticonvulsants diazepam and mk-801; these drugs were without effect in the ca3 or hilar interneuronal regions. |
1991-04-09 |
2023-08-11 |
rat |
| J J Hagan, M Beaughar. The effects of forebrain ischaemia on spatial learning. Behavioural brain research. vol 41. issue 2. 1991-04-04. PMID:2288667. |
the behavioural deficits were associated with neuropathological damage in the ca1 cell layer of the dorsal hippocampus with varying degrees of damage in layers ca2, ca3 and ca4. |
1991-04-04 |
2023-08-11 |
rat |
| J E Franck, D L Robert. Combined kainate and ischemia produces 'mesial temporal sclerosis'. Neuroscience letters. vol 118. issue 2. 1991-02-28. PMID:2274264. |
in the hippocampi of individuals with temporal lobe epilepsy, cells in ca1, ca3, and the dentate hilus are often gone, but dentate granule cells and ca2 are relatively spared. |
1991-02-28 |
2023-08-11 |
Not clear |