| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M P Mattson, P B Guthrie, S B Kate. Intrinsic factors in the selective vulnerability of hippocampal pyramidal neurons. Progress in clinical and biological research. vol 317. 1990-01-31. PMID:2690106. |
selective degeneration of pyramidal neurons in regions ca1 and ca3 of the hippocampus is a common structural correlate of several neurodegenerative conditions including alzheimer's disease, epilepsy and stroke. |
1990-01-31 |
2023-08-11 |
rat |
| M P Mattson, P B Guthrie, S B Kate. Intrinsic factors in the selective vulnerability of hippocampal pyramidal neurons. Progress in clinical and biological research. vol 317. 1990-01-31. PMID:2690106. |
the first paradigm consisted of neurons isolated from different hippocampal regions (ca1, ca2, ca3, dentate gyrus). |
1990-01-31 |
2023-08-11 |
rat |
| W Tack, A Wree, A Schleiche. Local cerebral glucose utilization in the hippocampus of old rats. Histochemistry. vol 92. issue 5. 1990-01-11. PMID:2584066. |
compared to young animals, in the old rats the lcgu was significantly reduced by 12% to 15% in the oriens layers of ca1 and ca2, the pyramidal layers of the ca sectors 1-3, the radiatum and lacunosum-molecular layers of ca2 and ca3 and in the lucidum layer of ca3. |
1990-01-11 |
2023-08-11 |
rat |
| C M Picone, J C Grotta, R Earls, R Strong, J Dedma. Immunohistochemical determination of calcium-calmodulin binding predicts neuronal damage after global ischemia. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 9. issue 6. 1989-12-29. PMID:2511211. |
ischemic animals demonstrated reduced (grade 0 to 2) staining in the ca1 and ca3 regions immediately and 2 and 24 h after ischemia (p less than 0.01 for both regions at all three time intervals) indicating persistent binding of cam with ca2+ and target proteins in these regions. |
1989-12-29 |
2023-08-11 |
rat |
| D V Lewis, L S Jones, D D Mot. Baclofen induces spontaneous, rhythmic sharp waves in the rat hippocampal slice. Experimental neurology. vol 106. issue 2. 1989-12-12. PMID:2509234. |
these low amplitude (0.1 to 0.3 mv) srsws were visible with high amplification in the extracellular recordings from the ca1, ca2, and ca3 regions and were roughly synchronous in all areas. |
1989-12-12 |
2023-08-11 |
rat |
| L M Ford, P R Sanberg, A B Norman, M H Fogelso. MK-801 prevents hippocampal neurodegeneration in neonatal hypoxic-ischemic rats. Archives of neurology. vol 46. issue 10. 1989-11-09. PMID:2552968. |
hippocampal neuronal damage in the ca1 and ca3 regions was prevented in animals pretreated with mk-801 vs saline-treated controls. |
1989-11-09 |
2023-08-11 |
rat |
| W E Stumpf, C Heiss, M Sar, G E Duncan, C Crave. Dexamethasone and corticosterone receptor sites. Differential topographic distribution in rat hippocampus revealed by high resolution autoradiography. Histochemistry. vol 92. issue 3. 1989-10-23. PMID:2777639. |
with 3h corticosterone, strongest nuclear labeling was observed in neurons in area ca2 and in the dorsomedial subiculum and indusium griseum, followed by area ca1, then ca3 and ca4; the dentate gyrus contained scattered strongly labeled cells among cells with intermediate nuclear labeling. |
1989-10-23 |
2023-08-11 |
rat |
| H Benveniste, M B Jørgensen, M Sandberg, T Christensen, H Hagberg, N H Dieme. Ischemic damage in hippocampal CA1 is dependent on glutamate release and intact innervation from CA3. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 9. issue 5. 1989-10-19. PMID:2570785. |
ischemic damage in hippocampal ca1 is dependent on glutamate release and intact innervation from ca3. |
1989-10-19 |
2023-08-11 |
Not clear |
| H Benveniste, M B Jørgensen, M Sandberg, T Christensen, H Hagberg, N H Dieme. Ischemic damage in hippocampal CA1 is dependent on glutamate release and intact innervation from CA3. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 9. issue 5. 1989-10-19. PMID:2570785. |
the removal of glutamatergic afferents to ca1 by destruction of the ca3 region is known to protect ca1 pyramidal cells against 10 min of transient global ischemia. |
1989-10-19 |
2023-08-11 |
Not clear |
| H Benveniste, M B Jørgensen, M Sandberg, T Christensen, H Hagberg, N H Dieme. Ischemic damage in hippocampal CA1 is dependent on glutamate release and intact innervation from CA3. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 9. issue 5. 1989-10-19. PMID:2570785. |
it is concluded that the ischemia-induced damage of pyramidal cells in ca1 is dependent on glutamate release and intact innervation from ca3. |
1989-10-19 |
2023-08-11 |
Not clear |
| M P Mattson, S B Kate. Development and selective neurodegeneration in cell cultures from different hippocampal regions. Brain research. vol 490. issue 1. 1989-09-08. PMID:2569350. |
previous studies have shown that pyramidal neurons in hippocampal regions ca1 and ca3 are selectively vulnerable in several neurodegenerative disorders and that a subpopulation of pyramidal neurons in cell cultures of embryonic hippocampus are sensitive to glutamate neurotoxicity. |
1989-09-08 |
2023-08-11 |
rat |
| M P Mattson, S B Kate. Development and selective neurodegeneration in cell cultures from different hippocampal regions. Brain research. vol 490. issue 1. 1989-09-08. PMID:2569350. |
tissue corresponding to the dentate gyrus (dg) and regions ca1, ca2 and ca3 of ammon's horn was removed by microdissection from transverse hippocampal slices and was used to establish cultures of dissociated cells. |
1989-09-08 |
2023-08-11 |
rat |
| M P Mattson, S B Kate. Development and selective neurodegeneration in cell cultures from different hippocampal regions. Brain research. vol 490. issue 1. 1989-09-08. PMID:2569350. |
the rank order of the vulnerability of pyramidal-like neurons to glutamate-induced neurodegeneration between regions in culture was: dg less than ca2 less than ca3 less than ca1. |
1989-09-08 |
2023-08-11 |
rat |
| J L Stringer, J M Williamson, E W Lothma. Induction of paroxysmal discharges in the dentate gyrus: frequency dependence and relationship to afterdischarge production. Journal of neurophysiology. vol 62. issue 1. 1989-08-31. PMID:2754466. |
stimulating electrodes were placed in the ca3 region contralateral to the recording electrode (cca3) and in the ipsilateral angular bundle (ab) while recording in the ca1 pyramidal-cell layer or the granule-cell layer of the dentate gyrus. |
1989-08-31 |
2023-08-11 |
rat |
| M L Berger, H Lassmann, O Hornykiewic. Limbic seizures without brain damage after injection of low doses of kainic acid into the amygdala of freely moving rats. Brain research. vol 489. issue 2. 1989-08-11. PMID:2743156. |
after 10 min status epilepticus, we observed marginal neuronal damage with slight gliosis in both hippocampi (ca3 and ca1); after 30 min, hippocampal histopathology was more pronounced, with additional necrosis of the ipsilateral piriform cortex. |
1989-08-11 |
2023-08-11 |
rat |
| H Kojima, M Kowada, Y Katsut. Cellular substrates for epileptiform activity induced by repeated tetanic stimulation in hippocampal slices. Neurologia medico-chirurgica. vol 29. issue 1. 1989-08-10. PMID:2472557. |
using intact and transected hippocampal slices, we investigated the relationship between ca3 and ca1 subfields in the generation of stimulus train-induced bursting. |
1989-08-10 |
2023-08-11 |
Not clear |
| H Kojima, M Kowada, Y Katsut. Cellular substrates for epileptiform activity induced by repeated tetanic stimulation in hippocampal slices. Neurologia medico-chirurgica. vol 29. issue 1. 1989-08-10. PMID:2472557. |
after transection between ca3 and ca1, neither spontaneous nor triggered bursts could be induced or maintained in isolated ca1, where only small after-discharge bursts with higher bursting frequency were observed. |
1989-08-10 |
2023-08-11 |
Not clear |
| A Represa, C Chanez, M A Flexor, Y Ben-Ar. Development of the cholinergic system in control and intra-uterine growth retarded rat brain. Brain research. Developmental brain research. vol 47. issue 1. 1989-07-28. PMID:2736767. |
the different markers of the cholinergic system were estimated at p (postnatal day) 6, 9, 12, 15, 22 and 60 in cerebellum, hypothalamus, septum, striatum and ca1, ca3 and fascia dentata of the hippocampus. |
1989-07-28 |
2023-08-11 |
rat |
| H S Swartzwelder, C Ferrari, W W Anderson, W A Wilso. The drug MK-801 attenuates the development, but not the expression, of long-term potentiation and stimulus train-induced bursting in hippocampal slices. Neuropharmacology. vol 28. issue 5. 1989-07-11. PMID:2657480. |
in the present experiment, slices of hippocampus, prepared from rats, were electrically stimulated to produce either long-term potentiation of the ca1 population spike or stimulus train-induced epileptiform bursting in area ca3. |
1989-07-11 |
2023-08-11 |
rat |
| W Müller, U Misgeld, H D Lu. gamma-Aminobutyric acid-induced ion movements in the guinea pig hippocampal slice. Brain research. vol 484. issue 1-2. 1989-06-15. PMID:2469522. |
microdrop application of gaba to the pyramidal cell layer of ca3 or ca1 induced a decrease of [cl]o, while application to the dendritic layer of ca3 or ca1 induced an increase of [cl]o in addition. |
1989-06-15 |
2023-08-11 |
Not clear |