| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Morioka, K Fukunaga, S Yasugawa, S Nagahiro, Y Ushio, E Miyamot. Regional and temporal alterations in Ca2+/calmodulin-dependent protein kinase II and calcineurin in the hippocampus of rat brain after transient forebrain ischemia. Journal of neurochemistry. vol 58. issue 5. 1992-05-11. PMID:1313854. |
immunoreactivity and enzyme activity of cam kinase ii decreased in regions ca1 and ca3, and in the dentate gyrus, of the hippocampus early (6-12 h) after ischemia, but the decrease in immunoreactivity gradually recovered over time, except in the ca1 region. |
1992-05-11 |
2023-08-11 |
rat |
| J R Seckl, K L Dickson, C Yates, G Fin. Distribution of glucocorticoid and mineralocorticoid receptor messenger RNA expression in human postmortem hippocampus. Brain research. vol 561. issue 2. 1992-04-24. PMID:1666329. |
gr mrna was highly expressed in dentate gyrus, ca3 and ca4, but levels were significantly lower in ca1 and ca2. |
1992-04-24 |
2023-08-11 |
human |
| J R Seckl, K L Dickson, C Yates, G Fin. Distribution of glucocorticoid and mineralocorticoid receptor messenger RNA expression in human postmortem hippocampus. Brain research. vol 561. issue 2. 1992-04-24. PMID:1666329. |
mr mrna was also very highly expressed in hippocampus, with significantly higher levels in dentate gyrus and ca2, ca3 and ca4 than ca1. |
1992-04-24 |
2023-08-11 |
human |
| K Kitagawa, M Matsumoto, K Kuwabara, M Tagaya, T Ohtsuki, R Hata, H Ueda, N Handa, K Kimura, T Kamad. 'Ischemic tolerance' phenomenon detected in various brain regions. Brain research. vol 561. issue 2. 1992-04-24. PMID:1802339. |
single 10-min ischemia consistently caused neuronal damage in the hippocampal ca1, ca2, ca3 and ca4, layer iii/iv of the cerebral cortex, dorsolateral part of the caudoputamen and ventrolateral part of the thalamus. |
1992-04-24 |
2023-08-11 |
Not clear |
| D T Chalmers, S J Watso. Comparative anatomical distribution of 5-HT1A receptor mRNA and 5-HT1A binding in rat brain--a combined in situ hybridisation/in vitro receptor autoradiographic study. Brain research. vol 561. issue 1. 1992-04-16. PMID:1797349. |
high levels of both 5-ht1a mrna and 5-ht1a receptors were evident in the hippocampal formation (ca1, ca3, dentate gyrus), entorhinal cortex, and raphe nuclei and lower levels in neocortex and thalamus. |
1992-04-16 |
2023-08-11 |
rat |
| N Lindefors, P Ernfors, T Falkenberg, H Persso. Septal cholinergic afferents regulate expression of brain-derived neurotrophic factor and beta-nerve growth factor mRNA in rat hippocampus. Experimental brain research. vol 88. issue 1. 1992-04-03. PMID:1541364. |
both bdnf and ngf mrna levels increased more than 4-fold in the granule layer of the dentate gyrus and for bdnf mrna also in the pyramidal cells of ca1, while the levels of bdnf mrna in ca3 increased 2-fold. |
1992-04-03 |
2023-08-11 |
rat |
| G Lallement, P Carpentier, A Collet, I Pernot-Marino, D Baubichon, G Blanche. Effects of soman-induced seizures on different extracellular amino acid levels and on glutamate uptake in rat hippocampus. Brain research. vol 563. issue 1-2. 1992-03-23. PMID:1786536. |
extracellular amino acid levels in ca3 and ca1 fields of rat hippocampus, an area highly sensitive to seizures, were determined by intracranial microdialysis during seizures induced by systemic administration of soman (o-1,2,2-trimethylpropyl methylphosphonofluoridate), a potent inhibitor of acetylcholinesterase. |
1992-03-23 |
2023-08-11 |
rat |
| G Lallement, P Carpentier, A Collet, I Pernot-Marino, D Baubichon, G Blanche. Effects of soman-induced seizures on different extracellular amino acid levels and on glutamate uptake in rat hippocampus. Brain research. vol 563. issue 1-2. 1992-03-23. PMID:1786536. |
the role of the transient release of glutamate in ca3 and of the sustained release in ca1 in prolonged soman-induced seizures is considered. |
1992-03-23 |
2023-08-11 |
rat |
| J W Geddes, L Brunner, C W Cotman, G Buzsák. Alterations in [3H]kainate and N-methyl-D-aspartate-sensitive L-[3H]-glutamate binding in the rat hippocampal formation following fimbria-fornix lesions. Experimental neurology. vol 115. issue 2. 1992-03-10. PMID:1310474. |
at 5 days post-lesion, the ca3 and ca1 strata radiatum and oriens displayed a decrease (20-42%, p less than 0.01) in nmda-sensitive l-[3h]glutamate binding. |
1992-03-10 |
2023-08-11 |
rat |
| E Gould, C S Woolley, B S McEwe. Short-term glucocorticoid manipulations affect neuronal morphology and survival in the adult dentate gyrus. Neuroscience. vol 37. issue 2. 1992-03-10. PMID:2133348. |
in contrast, no obvious signs of degeneration were detected in the pyramidal cell layers of the ca1 and ca3 regions of the hippocampus at either three or seven days following adrenalectomy. |
1992-03-10 |
2023-08-11 |
rat |
| H Hörtnagl, M L Berger, G Sperk, C Pif. Regional heterogeneity in the distribution of neurotransmitter markers in the rat hippocampus. Neuroscience. vol 45. issue 2. 1992-02-07. PMID:1684835. |
the concentrations of somatostatin were highest in ca1; those of serotonin were highest in ca3. |
1992-02-07 |
2023-08-11 |
rat |
| T Mizutani, H Shimad. Quantitative study of neurofibrillary tangles in subdivisions of the hippocampus. CA2 as a special area in normal aging and senile dementia of the Alzheimer type. Acta pathologica japonica. vol 41. issue 8. 1992-01-17. PMID:1750357. |
the regions were ca4, ca3, ca2 and ca1, the latter being subdivided into ca1a (the region near ca2) and ca1b (the region near the subiculum). |
1992-01-17 |
2023-08-11 |
Not clear |
| D Dewar, D T Chalmers, D I Graham, J McCulloc. Glutamate metabotropic and AMPA binding sites are reduced in Alzheimer's disease: an autoradiographic study of the hippocampus. Brain research. vol 553. issue 1. 1991-12-24. PMID:1933277. |
the regional distribution of glutamate metabotropic binding and ampa binding were similar, being most abundant in the subiculum and ca1 region and lower in the ca3 region. |
1991-12-24 |
2023-08-11 |
human |
| H Benvenist. The excitotoxin hypothesis in relation to cerebral ischemia. Cerebrovascular and brain metabolism reviews. vol 3. issue 3. 1991-12-13. PMID:1931486. |
there appeared to be a clear correlation between ischemia-induced glutamate accumulation and the decrease in extracellular calcium since both changes were prevented in the denervated ca1 (the destruction of glutamatergic innervation from ca3 protects ca1 pyramidal neurons from ischemic damage). |
1991-12-13 |
2023-08-11 |
rat |
| S M Strain, R A Taske. Hippocampal damage produced by systemic injections of domoic acid in mice. Neuroscience. vol 44. issue 2. 1991-12-05. PMID:1944890. |
with both toxins the most extensive damage was always observed in the ca3 region of the hippocampus, with lesser degrees of damage observed in other hippocampal regions (ca4 greater than ca1 greater than ca2 greater than dentate granule cells). |
1991-12-05 |
2023-08-11 |
mouse |
| H Hörtnagl, M L Berger, H Reither, O Hornykiewic. Cholinergic deficit induced by ethylcholine aziridinium (AF64A) in rat hippocampus: effect on glutamatergic systems. Naunyn-Schmiedeberg's archives of pharmacology. vol 344. issue 2. 1991-12-02. PMID:1682822. |
on the other hand, the transient reduction in glutamate was restricted to the ca1 and ca3 area. |
1991-12-02 |
2023-08-11 |
rat |
| N Lowe, Y H Edwards, M Edwards, P H Butterwort. Physical mapping of the human carbonic anhydrase gene cluster on chromosome 8. Genomics. vol 10. issue 4. 1991-11-04. PMID:1916821. |
the genes lie in the order ca2, ca3, ca1. |
1991-11-04 |
2023-08-11 |
mouse |
| N Lowe, Y H Edwards, M Edwards, P H Butterwort. Physical mapping of the human carbonic anhydrase gene cluster on chromosome 8. Genomics. vol 10. issue 4. 1991-11-04. PMID:1916821. |
ca2 and ca3 are separated by 20 kb and are transcribed in the same direction, away from ca1. |
1991-11-04 |
2023-08-11 |
mouse |
| N Lowe, Y H Edwards, M Edwards, P H Butterwort. Physical mapping of the human carbonic anhydrase gene cluster on chromosome 8. Genomics. vol 10. issue 4. 1991-11-04. PMID:1916821. |
ca1 is separated from ca3 by over 80 kb and is transcribed in the direction opposite to ca2 and ca3. |
1991-11-04 |
2023-08-11 |
mouse |
| N Lowe, Y H Edwards, M Edwards, P H Butterwort. Physical mapping of the human carbonic anhydrase gene cluster on chromosome 8. Genomics. vol 10. issue 4. 1991-11-04. PMID:1916821. |
the arrangement of the genes is consistent with proposals that the duplication event which gave rise to ca1 predated the duplication which gave rise to ca2 and ca3. |
1991-11-04 |
2023-08-11 |
mouse |