| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M P Witter, D G Amara. Entorhinal cortex of the monkey: V. Projections to the dentate gyrus, hippocampus, and subicular complex. The Journal of comparative neurology. vol 307. issue 3. 1991-08-28. PMID:1713237. |
projections to the dentate gyrus, and fields ca3 and ca2 of the hippocampus, originated preferentially in layers ii and vi of the entorhinal cortex whereas projections to ca1 and to the subiculum originated mainly in layers iii and v. anterograde tracing experiments demonstrated that all regions of the entorhinal cortex project to the outer two-thirds of the molecular layer of the dentate gyrus and to much of the radial extent of the stratum lacunosum-moleculare of ca3 and ca2. |
1991-08-28 |
2023-08-11 |
rat |
| Z Oláh, S Komoly, N Nagashima, F Joó, U R Rapp, W B Anderso. Cerebral ischemia induces transient intracellular redistribution and intranuclear translocation of the raf proto-oncogene product in hippocampal pyramidal cells. Experimental brain research. vol 84. issue 2. 1991-08-13. PMID:2065747. |
non-occluded hemisphere) neurons of ca1 and ca3 subfields 4 days after the ischemic insult indicating a possible transsynaptic increase in the amount of raf protein along with redistribution. |
1991-08-13 |
2023-08-11 |
Not clear |
| O Bengoechea, L M Gonzal. Effects of alcoholization on the rat hippocampus. Neuroscience letters. vol 123. issue 1. 1991-08-02. PMID:2062446. |
the neuron loss in group a, with respect to group c was: highly significant (p less than 0.001) for ca2; very significant (p less than 0.01) for ca3 and ca4; in ca1 and gd the reduction was not significant. |
1991-08-02 |
2023-08-11 |
rat |
| N Hori, N Doi, S Miyahara, Y Shinoda, D O Carpente. Appearance of NMDA receptors triggered by anoxia independent of voltage in vivo and in vitro. Experimental neurology. vol 112. issue 3. 1991-06-17. PMID:1827626. |
after anoxic damage to the intact animal, neurons in both ca1 and ca3 show abnormal bursting discharges in response to synaptic activation for several days, and then the response in ca1 decreases in amplitude and finally the area become unexcitable. |
1991-06-17 |
2023-08-11 |
rat |
| N Hori, N Doi, S Miyahara, Y Shinoda, D O Carpente. Appearance of NMDA receptors triggered by anoxia independent of voltage in vivo and in vitro. Experimental neurology. vol 112. issue 3. 1991-06-17. PMID:1827626. |
however, a period of hyperexcitability and bursting follows and electrical excitability is lost in ca1 but not ca3 neurons after about 90 min. |
1991-06-17 |
2023-08-11 |
rat |
| A Mitani, F Kadoya, Y Nakamura, K Kataok. Visualization of hypoxia-induced glutamate release in gerbil hippocampal slice. Neuroscience letters. vol 122. issue 2. 1991-06-07. PMID:2027517. |
the hypoxia-induced release of glutamate was gradually increased throughout the slice: no significant difference was detected among ca1 region, ca3 region and the dentate gyrus. |
1991-06-07 |
2023-08-11 |
Not clear |
| M Lerner-Natoli, G Rondouin, M Belaidi, M Baldy-Moulinier, J M Kamenk. N-[1-(2-thienyl)cyclohexyl]-piperidine (TCP) does not block kainic acid-induced status epilepticus but reduces secondary hippocampal damage. Neuroscience letters. vol 122. issue 2. 1991-06-07. PMID:2027518. |
distant damage, localized in the ca3 and ca1 areas, was observed in the hippocampus of rats as a consequence of status epilepticus (se) induced by the injection of 2.5 nmol of kainic acid (ka) into the amygdala. |
1991-06-07 |
2023-08-11 |
rat |
| D Jaarsma, J B Sebens, J Kor. Reduction of adenosine A1-receptors in the perforant pathway terminal zone in Alzheimer hippocampus. Neuroscience letters. vol 121. issue 1-2. 1991-05-29. PMID:1850501. |
the ca1 and the ca3, in spite of a pronounced cellular pathology and reduced n-methyl-d-aspartate (nmda) receptor densities, assessed as strychnine insensitive [3h]glycine autoradiography. |
1991-05-29 |
2023-08-11 |
rat |
| W Stummer, K Weber, L Schürer, A Baethmann, O Kempsk. Electrical impedance, rCBF, survival and histology in Mongolian gerbils with forebrain ischaemia. Acta neurochirurgica. Supplementum. vol 51. 1991-05-24. PMID:2089890. |
neuronal loss was found in all animals in the hippocampus (ca1, ca2, ca3 and ca4), and was most pronounced in the ca1 sector. |
1991-05-24 |
2023-08-11 |
Not clear |
| M F Gonzalez, D Lowenstein, S Fernyak, K Hisanaga, R Simon, F R Shar. Induction of heat shock protein 72-like immunoreactivity in the hippocampal formation following transient global ischemia. Brain research bulletin. vol 26. issue 2. 1991-05-16. PMID:2012984. |
it is proposed that (a) the induction of hsp72 in hippocampal sectors correlates with their vulnerability to global ischemia (ca1 greater than hilus greater than ca3 greater than dentate gyrus); (b) the induction of hsp72 in hippocampal cells correlates with their vulnerability to global ischemia in that mild ischemia induced hsp72 only in neurons, moderate ischemia in neurons and glia, and severe ischemia only in capillary endothelial cells; (c) the failure to induce hsp72 in hippocampal neurons in 2 cases of 10 min ischemia may be related to severe injury causing disruption of protein synthesis in these cells. |
1991-05-16 |
2023-08-11 |
rat |
| G J Lees, A Lehmann, M Sandberg, A Hamberge. The neurotoxicity of ouabain, a sodium-potassium ATPase inhibitor, in the rat hippocampus. Neuroscience letters. vol 120. issue 2. 1991-04-09. PMID:1705675. |
the neuronal perikaryal death produced in the subicular, ca1 and ca2 regions was only partially decreased by intraperitoneal injections of the anticonvulsants diazepam and mk-801; these drugs were without effect in the ca3 or hilar interneuronal regions. |
1991-04-09 |
2023-08-11 |
rat |
| J J Hagan, M Beaughar. The effects of forebrain ischaemia on spatial learning. Behavioural brain research. vol 41. issue 2. 1991-04-04. PMID:2288667. |
the behavioural deficits were associated with neuropathological damage in the ca1 cell layer of the dorsal hippocampus with varying degrees of damage in layers ca2, ca3 and ca4. |
1991-04-04 |
2023-08-11 |
rat |
| J E Franck, D L Robert. Combined kainate and ischemia produces 'mesial temporal sclerosis'. Neuroscience letters. vol 118. issue 2. 1991-02-28. PMID:2274264. |
in the hippocampi of individuals with temporal lobe epilepsy, cells in ca1, ca3, and the dentate hilus are often gone, but dentate granule cells and ca2 are relatively spared. |
1991-02-28 |
2023-08-11 |
Not clear |
| R N Kalaria, S Sromek, B J Wilcox, J R Unnerstal. Hippocampal adenosine A1 receptors are decreased in Alzheimer's disease. Neuroscience letters. vol 118. issue 2. 1991-02-28. PMID:2274280. |
in view of previous evidence indicating that these receptors are associated with the perforant pathway and dendritic fields of the ca1 and ca3 regions, our findings suggest loss of the presynaptic a1 receptors on axon terminals of extrinsic pathways including the perforant path and intrinsic pyramidal neurons which release glutamate. |
1991-02-28 |
2023-08-11 |
human |
| G A Werther, M Abate, A Hogg, H Cheesman, B Oldfield, D Hards, P Hudson, B Power, K Freed, A C Heringto. Localization of insulin-like growth factor-I mRNA in rat brain by in situ hybridization--relationship to IGF-I receptors. Molecular endocrinology (Baltimore, Md.). vol 4. issue 5. 1991-02-25. PMID:2177145. |
in hippocampus, hybridization was to pyramidal cells of ammon's horn in ca1 and ca2 layers and dentate gyrus, with some labeling in ca3. |
1991-02-25 |
2023-08-11 |
human |
| K J Sass, T Lencz, M Westerveld, R A Novelly, D D Spencer, J H Ki. The neural substrate of memory impairment demonstrated by the intracarotid amobarbital procedure. Archives of neurology. vol 48. issue 1. 1991-02-14. PMID:1986726. |
after anteromedial temporal lobectomy, neuronal densities were established for hippocampal subfields ca1, ca2, and ca3; the hilum; and the dentate granule cell layer. |
1991-02-14 |
2023-08-11 |
Not clear |
| R Schmidt-Kastner, J Szymas, K A Hossman. Immunohistochemical study of glial reaction and serum-protein extravasation in relation to neuronal damage in rat hippocampus after ischemia. Neuroscience. vol 38. issue 2. 1991-02-01. PMID:1702195. |
neuronal damage in the hilus was manifested 3-8 h after ischemia; neurons in the ca1 and ca2 sector suffered delayed neuronal death after 48-72 h whereas the dentate gyrus and the ca3 sector were normal. |
1991-02-01 |
2023-08-11 |
rat |
| S B Churn, W C Taft, M S Billingsley, R E Blair, R J DeLorenz. Temperature modulation of ischemic neuronal death and inhibition of calcium/calmodulin-dependent protein kinase II in gerbils. Stroke. vol 21. issue 12. 1991-02-01. PMID:2264078. |
hyperthermic (39 degrees c) gerbils showed almost complete loss of neurons in the ca1 region (3.0 neurons/mm, n = 11) and extension of neuronal death into the ca2, ca3, and ca4 regions. |
1991-02-01 |
2023-08-11 |
Not clear |
| J W McDonald, F S Silverstein, M V Johnsto. MK-801 pretreatment enhances N-methyl-D-aspartate-mediated brain injury and increases brain N-methyl-D-aspartate recognition site binding in rats. Neuroscience. vol 38. issue 1. 1991-01-24. PMID:2255390. |
a 2 h mk-801 pretreatment produced a 30-50% increase in [3h]glutamate binding at n-methyl-d-aspartate preferring recognition sites in all four brain regions examined (areas ca1 and ca3 of the hippocampus, corpus striatum, cingulate cortex) in comparison with saline-treated controls (p less than 0.05, anova). |
1991-01-24 |
2023-08-11 |
rat |
| K J Sass, D D Spencer, J H Kim, M Westerveld, R A Novelly, T Lenc. Verbal memory impairment correlates with hippocampal pyramidal cell density. Neurology. vol 40. issue 11. 1990-12-10. PMID:2234424. |
after surgical removal of the mesial temporal lobe structures, 2 blinded observers established volumetric cell densities for hippocampal subfields ca1, ca2, ca3, the hilar area, and the granule cell layer of the area dentata. |
1990-12-10 |
2023-08-11 |
Not clear |