| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Bagetta, G Nisticó, J O Doll. Production of seizures and brain damage in rats by alpha-dendrotoxin, a selective K+ channel blocker. Neuroscience letters. vol 139. issue 1. 1992-11-06. PMID:1357602. |
whilst brain damage was seen bilaterally, significant neuronal loss occurred only in regions (ca1, ca3, ca4 and dg) ipsilateral to the site of injection. |
1992-11-06 |
2023-08-11 |
rat |
| J M Bronstein, P Micevych, P Popper, G Huez, D B Farber, C G Wasterlai. Long-lasting decreases of type II calmodulin kinase expression in kindled rat brains. Brain research. vol 584. issue 1-2. 1992-10-07. PMID:1325246. |
kindling decreased hippocampal cam kinase mrna by 30% in ca1, 34% in ca2, 35% in ca3 41% in ca4, and 29% in the dentate gyrus. |
1992-10-07 |
2023-08-11 |
rat |
| J W Harding, V I Cook, A V Miller-Wing, J M Hanesworth, M F Sardinia, K L Hall, J W Stobb, G N Swanson, J K Coleman, J W Wrigh. Identification of an AII(3-8) [AIV] binding site in guinea pig hippocampus. Brain research. vol 583. issue 1-2. 1992-09-18. PMID:1504842. |
this binding site, which is present in the pyramidal cell layer of ca1, ca2, ca3 of the hippocampus and dentate gyrus, binds aii(3-8) with high affinity (kd = 1.29 +/- 0.18 nm) in a saturable manner (bmax = 449 +/- 62 fmol/mg protein). |
1992-09-18 |
2023-08-11 |
Not clear |
| M M Dugich-Djordjevic, G Tocco, P A Lapchak, G M Pasinetti, I Najm, M Baudry, F Heft. Regionally specific and rapid increases in brain-derived neurotrophic factor messenger RNA in the adult rat brain following seizures induced by systemic administration of kainic acid. Neuroscience. vol 47. issue 2. 1992-09-03. PMID:1641125. |
the greatest increase (10-fold) occurred in the dentate granule cell layer, while pyramidal layers ca1, ca3, and ca4 exhibited increases of two- to six-fold. |
1992-09-03 |
2023-08-11 |
rat |
| M M Dugich-Djordjevic, G Tocco, P A Lapchak, G M Pasinetti, I Najm, M Baudry, F Heft. Regionally specific and rapid increases in brain-derived neurotrophic factor messenger RNA in the adult rat brain following seizures induced by systemic administration of kainic acid. Neuroscience. vol 47. issue 2. 1992-09-03. PMID:1641125. |
peak elevation of brain-derived neurotrophic factor messenger rna in ca1 hippocampal region was evident at 4 h in ca3, and in the dentate granule layer at 30 min postseizure. |
1992-09-03 |
2023-08-11 |
rat |
| L L Boatell, N Lindefors, M Ballarin, P Ernfors, N Mahy, H Persso. Activation of basal forebrain cholinergic neurons differentially regulates brain-derived neurotrophic factor mRNA expression in different projection areas. Neuroscience letters. vol 136. issue 2. 1992-08-28. PMID:1641192. |
in contrast, 7 h after an injection into the septum the level of bdnf mrna increased 3- to 5-fold in the dentate gyrus, throughout ca1 to ca3 in the hippocampus and in the piriform cortex. |
1992-08-28 |
2023-08-11 |
Not clear |
| S Khanna, J G Sinclai. Responses in the CA1 region of the rat hippocampus to a noxious stimulus. Experimental neurology. vol 117. issue 1. 1992-08-04. PMID:1618285. |
this suggested that noxious stimulus-induced ca1 synaptic depression is mediated at the apical dendritic region, perhaps postsynaptically at the dendrites and/or presynaptically on ca3 afferent terminals. |
1992-08-04 |
2023-08-11 |
rat |
| R A Padua, T Yamamoto, D Fyda, M A Sawchuk, J D Geiger, J I Nag. Autoradiographic analysis of [3H]Ryanodine binding sites in rat brain: regional distribution and the effects of lesions on sites in the hippocampus. Journal of chemical neuroanatomy. vol 5. issue 1. 1992-07-23. PMID:1605914. |
in experimental animals, intracerebral injections of kainic acid caused neuronal degeneration and a near total depletion of [3h]ryanodine binding sites in the dentate gyrus and in fields ca1, ca2 and ca3 of the hippocampus. |
1992-07-23 |
2023-08-11 |
rat |
| A Mitani, Y Andou, K Kataok. Selective vulnerability of hippocampal CA1 neurons cannot be explained in terms of an increase in glutamate concentration during ischemia in the gerbil: brain microdialysis study. Neuroscience. vol 48. issue 2. 1992-07-16. PMID:1351267. |
in the present study, we measured the levels of released glutamate during ischemia in field ca1 and field ca3, separately, and evaluated whether there are subregional differences in the concentration of released glutamate which could be a satisfactory explanation for the selective vulnerability of hippocampal neurons to ischemia. |
1992-07-16 |
2023-08-11 |
Not clear |
| A Mitani, Y Andou, K Kataok. Selective vulnerability of hippocampal CA1 neurons cannot be explained in terms of an increase in glutamate concentration during ischemia in the gerbil: brain microdialysis study. Neuroscience. vol 48. issue 2. 1992-07-16. PMID:1351267. |
extracellular glutamate levels were significantly increased during ischemia in both field ca1 and field ca3. |
1992-07-16 |
2023-08-11 |
Not clear |
| A Mitani, Y Andou, K Kataok. Selective vulnerability of hippocampal CA1 neurons cannot be explained in terms of an increase in glutamate concentration during ischemia in the gerbil: brain microdialysis study. Neuroscience. vol 48. issue 2. 1992-07-16. PMID:1351267. |
no significant differences were detected in the time-course of change in glutamate release and the levels of glutamate between field ca1 and field ca3. |
1992-07-16 |
2023-08-11 |
Not clear |
| M Nakamura, M Araki, K Oguro, T Masuzaw. Differential distribution of 68 Kd and 200 Kd neurofilament proteins in the gerbil hippocampus and their early distributional changes following transient forebrain ischemia. Experimental brain research. vol 89. issue 1. 1992-07-16. PMID:1601102. |
in the normal hippocampus, nf68-like immunoreactivity (nf68-li) was densely distributed in nerve processes in ca2, ca3 and the hilus of the dentate gyrus but was less intense in ca1. |
1992-07-16 |
2023-08-11 |
Not clear |
| M Nakamura, M Araki, K Oguro, T Masuzaw. Differential distribution of 68 Kd and 200 Kd neurofilament proteins in the gerbil hippocampus and their early distributional changes following transient forebrain ischemia. Experimental brain research. vol 89. issue 1. 1992-07-16. PMID:1601102. |
in contrast, processes with nf200-li appeared to be evenly distributed in ca1, ca2, ca3 and the dentate gyrus. |
1992-07-16 |
2023-08-11 |
Not clear |
| M Nakamura, M Araki, K Oguro, T Masuzaw. Differential distribution of 68 Kd and 200 Kd neurofilament proteins in the gerbil hippocampus and their early distributional changes following transient forebrain ischemia. Experimental brain research. vol 89. issue 1. 1992-07-16. PMID:1601102. |
four days after ischemia, when neuronal death of ca1 pyramidal cells had occurred, processes in ca1, particularly 68 kd components, showed marked decreases in number and staining intensity, although processes in most layers of ca2, ca3 and the dentate gyrus appeared to be stained similarly to normal brain. |
1992-07-16 |
2023-08-11 |
Not clear |
| C Moncada, B Arvin, E Le Peillet, B S Meldru. Non-NMDA antagonists protect against kainate more than AMPA toxicity in the rat hippocampus. Neuroscience letters. vol 133. issue 2. 1992-06-26. PMID:1816508. |
single focal injection of the excitatory amino acids (eaas) kainic acid (ka, 1.1 nmol/microliters) and (s)-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (s)-ampa, 6 nmol/microliters) into rat dorsal hippocampus resulted in widespread neurodegeneration with 90-100% loss of hippocampal pyramidal cells in ca1, ca2, ca3 and ca4 subfields, and 50-70% loss of dentate granule (dg) cells. |
1992-06-26 |
2023-08-11 |
rat |
| C Moncada, B Arvin, E Le Peillet, B S Meldru. Non-NMDA antagonists protect against kainate more than AMPA toxicity in the rat hippocampus. Neuroscience letters. vol 133. issue 2. 1992-06-26. PMID:1816508. |
focal injection of nmda (30 nmol/microliters) under the same conditions resulted in 70-90% loss of ca1 cells with less damage in ca2, ca3, ca4 and dg cells (30-50%, 10-30%, and 30-50%, respectively). |
1992-06-26 |
2023-08-11 |
rat |
| C Moncada, B Arvin, E Le Peillet, B S Meldru. Non-NMDA antagonists protect against kainate more than AMPA toxicity in the rat hippocampus. Neuroscience letters. vol 133. issue 2. 1992-06-26. PMID:1816508. |
infusion (30 mg/kg/3h), protected against ka toxicity in ca1, ca2 and dg cells, with no protection in ca3 and ca4. |
1992-06-26 |
2023-08-11 |
rat |
| D Paré, M deCurtis, R Lliná. Role of the hippocampal-entorhinal loop in temporal lobe epilepsy: extra- and intracellular study in the isolated guinea pig brain in vitro. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 12. issue 5. 1992-06-05. PMID:1578275. |
two patterns of eds were distinguished by performing simultaneous field potential recordings along the dentate gyrus (dg), ec, ca1, and ca3. |
1992-06-05 |
2023-08-11 |
human |
| D Paré, M deCurtis, R Lliná. Role of the hippocampal-entorhinal loop in temporal lobe epilepsy: extra- and intracellular study in the isolated guinea pig brain in vitro. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 12. issue 5. 1992-06-05. PMID:1578275. |
thereafter, population spikes occurred sequentially in the ca1 region, ec, dg, and back to the ca3 region. |
1992-06-05 |
2023-08-11 |
human |
| D Johnston, S Williams, D Jaffe, R Gra. NMDA-receptor-independent long-term potentiation. Annual review of physiology. vol 54. 1992-05-12. PMID:1314043. |
at the hippocampal ca3 mf synapse, activation of voltage-gated ca2+ channels has been proposed as a trigger for ltp induction, and this may also be the case for certain types of ltp at the sc synapse in ca1 (25, 40). |
1992-05-12 |
2023-08-11 |
Not clear |