| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Kawasaki, S F Traynelis, R Dingledin. Different responses of CA1 and CA3 regions to hypoxia in rat hippocampal slice. Journal of neurophysiology. vol 63. issue 3. 1990-05-29. PMID:2158521. |
in contrast to the ca1 region, the ca3 region could undergo spreading depression during hypoxia. |
1990-05-29 |
2023-08-11 |
rat |
| T Beck, A Wree, A Schleiche. Postischemic glucose utilization in rat hippocampal layers. Brain research. vol 510. issue 1. 1990-05-21. PMID:2322849. |
despite severe neuronal damage as assessed by histological techniques, local cerebral glucose utilization (lcgu) was significantly increased in the pyramidal and radiatum layer of the ca1 sector, while in layers of the ca2, ca3 and ca4 sector and dentate gyrus. |
1990-05-21 |
2023-08-11 |
rat |
| D G Muno. The distribution of chromogranin A-like immunoreactivity in the human hippocampus coincides with the pattern of resistance to epilepsy-induced neuronal damage. Annals of neurology. vol 27. issue 3. 1990-05-21. PMID:2327736. |
the two prominently immunoreactive neuronal populations, ca2 pyramids and dentate granule cells, are those spared in human and experimental epileptic brain damage, whereas ca1 and ca3 pyramids, lacking chromogranin, are characteristically destroyed in this condition. |
1990-05-21 |
2023-08-11 |
human |
| M M Haglund, P A Schwartzkroi. Role of Na-K pump potassium regulation and IPSPs in seizures and spreading depression in immature rabbit hippocampal slices. Journal of neurophysiology. vol 63. issue 2. 1990-04-13. PMID:2313342. |
we report here a difference between the ca1 and ca3 cell populations in the immature hippocampus with regard to 1) resting [k+]o, 2) magnitude of the [k+]o change during seizurelike events and sds, and 3) susceptibility to sd episodes. |
1990-04-13 |
2023-08-11 |
rabbit |
| M M Haglund, P A Schwartzkroi. Role of Na-K pump potassium regulation and IPSPs in seizures and spreading depression in immature rabbit hippocampal slices. Journal of neurophysiology. vol 63. issue 2. 1990-04-13. PMID:2313342. |
simultaneous intra- and extracellular recordings were made in the ca1 and ca3 regions of the immature rabbit hippocampus during spontaneous or evoked sd, while potassium ion-sensitive microelectrodes (k-isms) monitored changes in [k+]o. |
1990-04-13 |
2023-08-11 |
rabbit |
| M M Haglund, P A Schwartzkroi. Role of Na-K pump potassium regulation and IPSPs in seizures and spreading depression in immature rabbit hippocampal slices. Journal of neurophysiology. vol 63. issue 2. 1990-04-13. PMID:2313342. |
the ca1 region had 1) a higher frequency of spontaneous sd episodes than ca3, 2) a lower threshold to potassium-triggered sd, 3) a longer duration sd episode, and 4) smaller post-sd membrane potential and [k+]o undershoots (below the original resting membrane potential and resting [k+]o). |
1990-04-13 |
2023-08-11 |
rabbit |
| J P Herman, P D Patel, H Akil, S J Watso. Localization and regulation of glucocorticoid and mineralocorticoid receptor messenger RNAs in the hippocampal formation of the rat. Molecular endocrinology (Baltimore, Md.). vol 3. issue 11. 1990-02-15. PMID:2558306. |
both gr and mr mrnas were present in all subfields examined; gr mrna was of greatest abundance in ca1, while mr mrna was most densely labeled in ca3. |
1990-02-15 |
2023-08-11 |
rat |
| M P Mattson, P B Guthrie, S B Kate. Intrinsic factors in the selective vulnerability of hippocampal pyramidal neurons. Progress in clinical and biological research. vol 317. 1990-01-31. PMID:2690106. |
selective degeneration of pyramidal neurons in regions ca1 and ca3 of the hippocampus is a common structural correlate of several neurodegenerative conditions including alzheimer's disease, epilepsy and stroke. |
1990-01-31 |
2023-08-11 |
rat |
| M P Mattson, P B Guthrie, S B Kate. Intrinsic factors in the selective vulnerability of hippocampal pyramidal neurons. Progress in clinical and biological research. vol 317. 1990-01-31. PMID:2690106. |
the first paradigm consisted of neurons isolated from different hippocampal regions (ca1, ca2, ca3, dentate gyrus). |
1990-01-31 |
2023-08-11 |
rat |
| W Tack, A Wree, A Schleiche. Local cerebral glucose utilization in the hippocampus of old rats. Histochemistry. vol 92. issue 5. 1990-01-11. PMID:2584066. |
compared to young animals, in the old rats the lcgu was significantly reduced by 12% to 15% in the oriens layers of ca1 and ca2, the pyramidal layers of the ca sectors 1-3, the radiatum and lacunosum-molecular layers of ca2 and ca3 and in the lucidum layer of ca3. |
1990-01-11 |
2023-08-11 |
rat |
| C M Picone, J C Grotta, R Earls, R Strong, J Dedma. Immunohistochemical determination of calcium-calmodulin binding predicts neuronal damage after global ischemia. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 9. issue 6. 1989-12-29. PMID:2511211. |
ischemic animals demonstrated reduced (grade 0 to 2) staining in the ca1 and ca3 regions immediately and 2 and 24 h after ischemia (p less than 0.01 for both regions at all three time intervals) indicating persistent binding of cam with ca2+ and target proteins in these regions. |
1989-12-29 |
2023-08-11 |
rat |
| D V Lewis, L S Jones, D D Mot. Baclofen induces spontaneous, rhythmic sharp waves in the rat hippocampal slice. Experimental neurology. vol 106. issue 2. 1989-12-12. PMID:2509234. |
these low amplitude (0.1 to 0.3 mv) srsws were visible with high amplification in the extracellular recordings from the ca1, ca2, and ca3 regions and were roughly synchronous in all areas. |
1989-12-12 |
2023-08-11 |
rat |
| L M Ford, P R Sanberg, A B Norman, M H Fogelso. MK-801 prevents hippocampal neurodegeneration in neonatal hypoxic-ischemic rats. Archives of neurology. vol 46. issue 10. 1989-11-09. PMID:2552968. |
hippocampal neuronal damage in the ca1 and ca3 regions was prevented in animals pretreated with mk-801 vs saline-treated controls. |
1989-11-09 |
2023-08-11 |
rat |
| W E Stumpf, C Heiss, M Sar, G E Duncan, C Crave. Dexamethasone and corticosterone receptor sites. Differential topographic distribution in rat hippocampus revealed by high resolution autoradiography. Histochemistry. vol 92. issue 3. 1989-10-23. PMID:2777639. |
with 3h corticosterone, strongest nuclear labeling was observed in neurons in area ca2 and in the dorsomedial subiculum and indusium griseum, followed by area ca1, then ca3 and ca4; the dentate gyrus contained scattered strongly labeled cells among cells with intermediate nuclear labeling. |
1989-10-23 |
2023-08-11 |
rat |
| H Benveniste, M B Jørgensen, M Sandberg, T Christensen, H Hagberg, N H Dieme. Ischemic damage in hippocampal CA1 is dependent on glutamate release and intact innervation from CA3. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 9. issue 5. 1989-10-19. PMID:2570785. |
ischemic damage in hippocampal ca1 is dependent on glutamate release and intact innervation from ca3. |
1989-10-19 |
2023-08-11 |
Not clear |
| H Benveniste, M B Jørgensen, M Sandberg, T Christensen, H Hagberg, N H Dieme. Ischemic damage in hippocampal CA1 is dependent on glutamate release and intact innervation from CA3. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 9. issue 5. 1989-10-19. PMID:2570785. |
the removal of glutamatergic afferents to ca1 by destruction of the ca3 region is known to protect ca1 pyramidal cells against 10 min of transient global ischemia. |
1989-10-19 |
2023-08-11 |
Not clear |
| H Benveniste, M B Jørgensen, M Sandberg, T Christensen, H Hagberg, N H Dieme. Ischemic damage in hippocampal CA1 is dependent on glutamate release and intact innervation from CA3. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 9. issue 5. 1989-10-19. PMID:2570785. |
it is concluded that the ischemia-induced damage of pyramidal cells in ca1 is dependent on glutamate release and intact innervation from ca3. |
1989-10-19 |
2023-08-11 |
Not clear |
| M P Mattson, S B Kate. Development and selective neurodegeneration in cell cultures from different hippocampal regions. Brain research. vol 490. issue 1. 1989-09-08. PMID:2569350. |
previous studies have shown that pyramidal neurons in hippocampal regions ca1 and ca3 are selectively vulnerable in several neurodegenerative disorders and that a subpopulation of pyramidal neurons in cell cultures of embryonic hippocampus are sensitive to glutamate neurotoxicity. |
1989-09-08 |
2023-08-11 |
rat |
| M P Mattson, S B Kate. Development and selective neurodegeneration in cell cultures from different hippocampal regions. Brain research. vol 490. issue 1. 1989-09-08. PMID:2569350. |
tissue corresponding to the dentate gyrus (dg) and regions ca1, ca2 and ca3 of ammon's horn was removed by microdissection from transverse hippocampal slices and was used to establish cultures of dissociated cells. |
1989-09-08 |
2023-08-11 |
rat |
| M P Mattson, S B Kate. Development and selective neurodegeneration in cell cultures from different hippocampal regions. Brain research. vol 490. issue 1. 1989-09-08. PMID:2569350. |
the rank order of the vulnerability of pyramidal-like neurons to glutamate-induced neurodegeneration between regions in culture was: dg less than ca2 less than ca3 less than ca1. |
1989-09-08 |
2023-08-11 |
rat |