| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Weizhe Liu, Fang Han, Shuai Qu, Yuanfei Yao, Jianxiang Zhao, Muhammad Luqman Akhtar, Yanpeng Ci, Hao Zhang, Hongfei Li, Yufang Zhao, Lei Yue, Yao Zhang, Changlin Wang, Yu L. MARVELD1 depletion leads to dysfunction of motor and cognition via regulating glia-dependent neuronal migration during brain development. Cell death & disease. vol 9. issue 10. 2019-12-13. PMID:30250269. |
the laminar organization of the cerebral cortex and cerebellum in marveld1 knockout (ko) mice is disrupted, indicating impaired radial neuronal migration. |
2019-12-13 |
2023-08-13 |
mouse |
| Alexandra H Leighton, Christian Lohman. The Wiring of Developing Sensory Circuits-From Patterned Spontaneous Activity to Synaptic Plasticity Mechanisms. Frontiers in neural circuits. vol 10. 2019-11-20. PMID:27656131. |
as soon as the eyelids first open, neurons in the cortex respond to visual information without the animal having previously encountered structured sensory input (cang et al., 2005b; rochefort et al., 2011; zhang et al., 2012; ko et al., 2013). |
2019-11-20 |
2023-08-13 |
mouse |
| Marwan Mannaa, Lajos Markó, András Balogh, Emilia Vigolo, Gabriele N'diaye, Mario Kaßmann, Laura Michalick, Ulrike Weichelt, Kai M Schmidt-Ott, Wolfgang B Liedtke, Yu Huang, Dominik N Müller, Wolfgang M Kuebler, Maik Gollasc. Transient Receptor Potential Vanilloid 4 Channel Deficiency Aggravates Tubular Damage after Acute Renal Ischaemia Reperfusion. Scientific reports. vol 8. issue 1. 2019-11-04. PMID:29559678. |
detailed histological analysis revealed that iri caused aggravated renal tubular damage in trpv4 ko mice, especially in the renal cortex. |
2019-11-04 |
2023-08-13 |
mouse |
| Manoj Kumar Neog, Hyunju Chung, Min Joo Jang, Dong Jin Kim, Sang Ho Lee, Kyoung Soo Ki. Effect of Aging on Taurine Transporter (TauT) Expression in the Mouse Brain Cortex. Advances in experimental medicine and biology. vol 1155. 2019-09-19. PMID:31468381. |
moreover, taut expression in the brain cortex of 12- or 24-month-old mice did not significantly differ from age-matched nlrp3 ko mice. |
2019-09-19 |
2023-08-13 |
mouse |
| Gourango Talukdar, Ran Inoue, Tomoyuki Yoshida, Hisashi Mor. Impairment in extinction of cued fear memory in syntenin-1 knockout mice. Neurobiology of learning and memory. vol 149. 2019-09-16. PMID:29408273. |
this extinction retention deficit in syntenin-1 ko mice was associated with reduced c-fos-positive neurons in the basolateral amygdala (bla) and infralimbic cortex (il) after extinction training and increased c-fos-positive neurons in the bla after an extinction retention test. |
2019-09-16 |
2023-08-13 |
mouse |
| Bo Wang, Joung Hyuck Joo, Rebecca Mount, Brett J W Teubner, Alison Krenzer, Amber L Ward, Viraj P Ichhaporia, Elizabeth J Adams, Rami Khoriaty, Samuel T Peters, Shondra M Pruett-Miller, Stanislav S Zakharenko, David Ginsburg, Mondira Kund. The COPII cargo adapter SEC24C is essential for neuronal homeostasis. The Journal of clinical investigation. vol 128. issue 8. 2019-09-10. PMID:29939162. |
conditional ko of sec24c in neural progenitors during embryogenesis caused perinatal mortality and microcephaly, with activation of the unfolded protein response and apoptotic cell death of postmitotic neurons in the murine cerebral cortex. |
2019-09-10 |
2023-08-13 |
mouse |
| Ajmal Zemmar, Chia-Chien Chen, Oliver Weinmann, Brigitt Kast, Flora Vajda, James Bozeman, Noel Isaad, Yi Zuo, Martin E Schwa. Oligodendrocyte- and Neuron-Specific Nogo-A Restrict Dendritic Branching and Spine Density in the Adult Mouse Motor Cortex. Cerebral cortex (New York, N.Y. : 1991). vol 28. issue 6. 2019-09-06. PMID:28505229. |
finally, we used two-photon laser scanning microscopy to measure the spine turnover rate of adult mouse motor cortex layer 5 cells and find that both nogo-a ko mouse lines show enhanced spine remodeling after 4 days. |
2019-09-06 |
2023-08-13 |
mouse |
| Jonathan W Lovelace, Iryna M Ethell, Devin K Binder, Khaleel A Raza. Translation-relevant EEG phenotypes in a mouse model of Fragile X Syndrome. Neurobiology of disease. vol 115. 2019-09-06. PMID:29605426. |
the abnormal gamma oscillations are consistent with parvalbumin neuron and perineuronal net deficits seen in the fmr1 ko mouse auditory cortex indicating that the eeg biomarkers are not only clinically relevant, but could also be used to probe cellular and circuit mechanisms of sensory hypersensitivity in fxs. |
2019-09-06 |
2023-08-13 |
mouse |
| Maham Rais, Devin K Binder, Khaleel A Razak, Iryna M Ethel. Sensory Processing Phenotypes in Fragile X Syndrome. ASN neuro. vol 10. 2019-07-11. PMID:30231625. |
fmr1 ko mice also show impaired encoding of tactile stimulation frequency and larger size of receptive fields in the somatosensory cortex. |
2019-07-11 |
2023-08-13 |
mouse |
| D Mielenz, M Reichel, T Jia, E B Quinlan, T Stöckl, M Mettang, D Zilske, E Kirmizi-Alsan, P Schönberger, M Praetner, S E Huber, D Amato, M Schwarz, P Purohit, S Brachs, J Spranger, A Hess, C Büttner, A B Ekici, F Perez-Branguli, B Winner, V Rauschenberger, T Banaschewski, A L W Bokde, C Büchel, P J Conrod, S Desrivières, H Flor, V Frouin, J Gallinat, H Garavan, P Gowland, A Heinz, J-L Martinot, H Lemaitre, F Nees, T Paus, M N Smolka, A Schambony, T Bäuerle, V Eulenburg, C Alzheimer, A Lourdusamy, G Schumann, C P Mülle. EFhd2/Swiprosin-1 is a common genetic determinator for sensation-seeking/low anxiety and alcohol addiction. Molecular psychiatry. vol 23. issue 5. 2019-03-27. PMID:28397836. |
in confirmation, gene expression analysis revealed reduced tyrosine hydroxylase expression and the regulation of genes involved in cortex development, eomes and pax6, in efhd2 ko cortices. |
2019-03-27 |
2023-08-13 |
mouse |
| Marine H Laporte, Christine Chatellard, Victoria Vauchez, Fiona J Hemming, Jean-Christophe Deloulme, Frédérique Vossier, Béatrice Blot, Sandrine Fraboulet, Rémy Sadou. Alix is required during development for normal growth of the mouse brain. Scientific reports. vol 7. 2018-11-09. PMID:28322231. |
indeed, embryonic surface expansion of the alix ko cortex is reduced because of the loss of neural progenitors during a transient phase of apoptosis occurring between e11.5 and e12.5. |
2018-11-09 |
2023-08-13 |
mouse |
| Marine H Laporte, Christine Chatellard, Victoria Vauchez, Fiona J Hemming, Jean-Christophe Deloulme, Frédérique Vossier, Béatrice Blot, Sandrine Fraboulet, Rémy Sadou. Alix is required during development for normal growth of the mouse brain. Scientific reports. vol 7. 2018-11-09. PMID:28322231. |
subsequent development of the alix ko cortex occurs normally until birth, when alix is again required for the post-natal radial expansion of the cortex through its capacity to allow proper neurite outgrowth. |
2018-11-09 |
2023-08-13 |
mouse |
| Hiroshi Ogi, Nobuhiro Nitta, So Tando, Akira Fujimori, Ichio Aoki, Shinji Fushiki, Kyoko Ito. Longitudinal Diffusion Tensor Imaging Revealed Nerve Fiber Alterations in Aspm Mutated Microcephaly Model Mice. Neuroscience. vol 371. 2018-11-09. PMID:29253521. |
voxel-based statistics showed that the fractional anisotropy (fa) values were significantly lower in aspm ko mice in both the cortex and white matter at both time points. |
2018-11-09 |
2023-08-13 |
mouse |
| Mark R Zielinski, Dmitry Gerashchenko, Svetlana A Karpova, Varun Konanki, Robert W McCarley, Fayyaz S Sutterwala, Robert E Strecker, Radhika Bashee. The NLRP3 inflammasome modulates sleep and NREM sleep delta power induced by spontaneous wakefulness, sleep deprivation and lipopolysaccharide. Brain, behavior, and immunity. vol 62. 2018-08-29. PMID:28109896. |
nlrp3, asc, and il1β mrna, il-1β protein, and caspase-1 activity were greater in the somatosensory cortex at the end of the wake-active period when sleep propensity was high and after sd in wild-type but not nlrp3 ko mice. |
2018-08-29 |
2023-08-13 |
mouse |
| Bo Jiang, Guohao Liu, Jiashuo Zheng, Mengxia Chen, Zaitunamu Maimaitiming, Min Chen, Shunli Liu, Ruiwei Jiang, Brie K Fuqua, Joshua L Dunaief, Chris D Vulpe, Gregory J Anderson, Hongwei Wang, Huijun Che. Hephaestin and ceruloplasmin facilitate iron metabolism in the mouse kidney. Scientific reports. vol 6. 2018-07-23. PMID:27991585. |
the non-heme iron content both in the renal cortex and medulla of heph/cp ko mice was significantly increased. |
2018-07-23 |
2023-08-13 |
mouse |
| Bo Jiang, Guohao Liu, Jiashuo Zheng, Mengxia Chen, Zaitunamu Maimaitiming, Min Chen, Shunli Liu, Ruiwei Jiang, Brie K Fuqua, Joshua L Dunaief, Chris D Vulpe, Gregory J Anderson, Hongwei Wang, Huijun Che. Hephaestin and ceruloplasmin facilitate iron metabolism in the mouse kidney. Scientific reports. vol 6. 2018-07-23. PMID:27991585. |
a significant increase in ferritin protein expression was also observed in the renal medulla and cortex of heph/cp ko mice. |
2018-07-23 |
2023-08-13 |
mouse |
| Bo Jiang, Guohao Liu, Jiashuo Zheng, Mengxia Chen, Zaitunamu Maimaitiming, Min Chen, Shunli Liu, Ruiwei Jiang, Brie K Fuqua, Joshua L Dunaief, Chris D Vulpe, Gregory J Anderson, Hongwei Wang, Huijun Che. Hephaestin and ceruloplasmin facilitate iron metabolism in the mouse kidney. Scientific reports. vol 6. 2018-07-23. PMID:27991585. |
both dmt1 and tfr1 protein expression were significantly decreased in the renal medulla of heph/cp ko mice, while the expression of dmt1 protein was significantly increased in the renal cortex of these animals. |
2018-07-23 |
2023-08-13 |
mouse |
| Kei Hashimoto, Natsumi Ikeda, Mari Nakashima, Hiroko Ikeshima-Kataoka, Yasunori Miyamot. Vitronectin Regulates the Fibrinolytic System during the Repair of Cerebral Cortex in Stab-Wounded Mice. Journal of neurotrauma. vol 34. issue 22. 2018-06-28. PMID:28683586. |
we examined the effects of vn on the fibrinolytic system in the stab-wounded cerebral cortex of vn-knockout (ko) mice. |
2018-06-28 |
2023-08-13 |
mouse |
| Qi Wang, Evanthia Mergia, Doris Koesling, Thomas Mittman. Nitric oxide/cGMP signaling via guanylyl cyclase isoform 1 modulates glutamate and GABA release in somatosensory cortex of mice. Neuroscience. vol 360. 2018-06-05. PMID:28782641. |
in the present study, we used knock-out mice deficient for the no-gc1 isoform (no-gc1 ko) to analyze its role in the glutamatergic and gabaergic neurotransmission at pyramidal neurons in layers ii/iii of somatosensory cortex. |
2018-06-05 |
2023-08-13 |
mouse |
| Anand Suresh, Anna Dunaevsk. Relationship Between Synaptic AMPAR and Spine Dynamics: Impairments in the FXS Mouse. Cerebral cortex (New York, N.Y. : 1991). vol 27. issue 8. 2018-05-01. PMID:28541473. |
here, we tracked ampar and spines over multiple days in vivo in the cortex and found that dendritic spines in the fmr1 ko mouse were denser, smaller, had higher turnover rates and contained less sglua2 compared to littermate controls. |
2018-05-01 |
2023-08-13 |
mouse |