| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Asmae Lguensat, Christian Montanari, Cassandre Vielle, Mohamed Bennis, Saadia Ba-M'hamed, Christelle Baunez, René Garci. Repeated cocaine exposure prior to fear conditioning induces persistency of PTSD-like symptoms and enhancement of hippocampal and amygdala cell density in male rats. Brain structure & function. vol 226. issue 7. 2021-08-11. PMID:34195855. |
repeated cocaine exposure prior to fear conditioning induces persistency of ptsd-like symptoms and enhancement of hippocampal and amygdala cell density in male rats. |
2021-08-11 |
2023-08-13 |
rat |
| Robert H Oakley, Shannon D Whirledge, Maria G Petrillo, Natallia V Riddick, Xiaojiang Xu, Sheryl S Moy, John A Cidlowsk. Combinatorial actions of glucocorticoid and mineralocorticoid stress hormone receptors are required for preventing neurodegeneration of the mouse hippocampus. Neurobiology of stress. vol 15. 2021-08-10. PMID:34368410. |
mice lacking mr alone or both gr and mr in the hippocampus exhibited altered expression of multiple ca2-specific neuronal markers and enhanced cue-dependent learning in a conditioned fear test. |
2021-08-10 |
2023-08-13 |
mouse |
| Yanmei Chen, Na Kang, Jingsheng Gu, Boling Chu, Lilu Luo, Yingjie An, Fengyuan Yang, Jun Cao, Jichuan Zhan. Inactivation of endopeduncular nucleus impaired fear conditioning and hippocampal synaptic plasticity in rats. Neurobiology of learning and memory. vol 173. 2021-07-27. PMID:32246991. |
inactivation of endopeduncular nucleus impaired fear conditioning and hippocampal synaptic plasticity in rats. |
2021-07-27 |
2023-08-13 |
rat |
| Yulia K Komleva, Olga L Lopatina, Iana V Gorina, Anton N Shuvaev, Anatoly Chernykh, Ilia V Potapenko, Alla B Salmin. NLRP3 deficiency-induced hippocampal dysfunction and anxiety-like behavior in mice. Brain research. vol 1752. 2021-07-22. PMID:33358726. |
these include the following: anxious behavior and deterioration in learning and memory of fear conditioning; impairment of adult neurogenesis; reduction and altered morphology of astrocytes in the brain; hyperexcitability in basolateral amygdala (bla); impaired activation in axons of pyramidal cells of ca1 hippocampal zone in nlrp3 ko mice particularly via the schaffer collateral pathway; and impaired synaptic transduction in pyramidal cells mediated by an embarrassment of neurotransmitter release from presynaptic site in ca3 hippocampal zone. |
2021-07-22 |
2023-08-13 |
mouse |
| Xiaoyu Cui, Songhua Zhou, Guang Xia, Jie Chen, Lizhu Jiang, Jufang Huang, Jianbin Ton. A multispecies probiotic accelerates fear extinction and inhibits relapse in mice: Role of microglia. Neuropharmacology. vol 193. 2021-07-21. PMID:34022177. |
we found that fear conditioning induced synapse loss, microglial activation, and synaptic phagocytosis of activated microglial cells in hippocampal dentate gyrus of mice. |
2021-07-21 |
2023-08-13 |
mouse |
| Yann S Mineur, Charlotte Ernstsen, Ashraful Islam, Kathrine Lefoli Maibom, Marina R Picciott. Hippocampal knockdown of α2 nicotinic or M1 muscarinic acetylcholine receptors in C57BL/6J male mice impairs cued fear conditioning. Genes, brain, and behavior. vol 19. issue 6. 2021-07-16. PMID:32447811. |
hippocampal knockdown of α2 nicotinic or m1 muscarinic acetylcholine receptors in c57bl/6j male mice impairs cued fear conditioning. |
2021-07-16 |
2023-08-13 |
mouse |
| Yann S Mineur, Charlotte Ernstsen, Ashraful Islam, Kathrine Lefoli Maibom, Marina R Picciott. Hippocampal knockdown of α2 nicotinic or M1 muscarinic acetylcholine receptors in C57BL/6J male mice impairs cued fear conditioning. Genes, brain, and behavior. vol 19. issue 6. 2021-07-16. PMID:32447811. |
short term learning was intact immediately after training in all groups of mice, but both the m1 and α2 hippocampal knock down resulted in impaired cued fear conditioning 24 h after training. |
2021-07-16 |
2023-08-13 |
mouse |
| Chun Wang, Xu Cao, Jing Yin, Wen-Rui Gao, Wei-Ran Li, Jin-Shun Qi, Mei-Na W. [Chronic sleep deprivation exacerbates cognitive and pathological impairments in APP/PS1/tau triple transgenic Alzheimer's disease model mice]. Sheng li xue bao : [Acta physiologica Sinica]. vol 73. issue 3. 2021-07-08. PMID:34230948. |
the results showed that: (1) chronic sleep deprivation did not affect anxiety- (p = 0.539) and depression-like behaviors (p = 0.874) in 3xtg-ad mice; (2) chronic sleep deprivation exacerbated the impairments of object recognition memory (p < 0.001), working memory (p = 0.002) and the conditioned fear memory (p = 0.039) in 3xtg-ad mice; (3) chronic sleep deprivation increased amyloid β (aβ) deposition (p < 0.001) and microglial activation (p < 0.001) in the hippocampus of 3xtg-ad mice, without inducing abnormal tau phosphorylation and neurofibrillary tangles. |
2021-07-08 |
2023-08-13 |
mouse |
| Chun Wang, Xu Cao, Jing Yin, Wen-Rui Gao, Wei-Ran Li, Jin-Shun Qi, Mei-Na W. [Chronic sleep deprivation exacerbates cognitive and pathological impairments in APP/PS1/tau triple transgenic Alzheimer's disease model mice]. Sheng li xue bao : [Acta physiologica Sinica]. vol 73. issue 3. 2021-07-08. PMID:34230948. |
these results indicate that chronic sleep deprivation exacerbates the impairments of recognition memory, working memory and conditioned fear memory in 3xtg-ad mice by aggravating aβ deposition and the excessive activation of microglia in the hippocampus. |
2021-07-08 |
2023-08-13 |
mouse |
| Jung-Pyo Oh, Jin-Hee Ha. A critical role of hippocampus for formation of remote cued fear memory. Molecular brain. vol 13. issue 1. 2021-07-07. PMID:32799906. |
here, using a pharmacological reversible inactivation of dorsal hippocampus in auditory cued fear conditioning by local infusion of muscimol, we demonstrate in mice that hippocampus is critical for remote memory formation of learned fear to the discrete sensory cue. |
2021-07-07 |
2023-08-13 |
mouse |
| Masatoshi Takita, Yumi Izawa-Sugay. Neurocircuit differences between memory traces of persistent hypoactivity and freezing following fear conditioning among the amygdala, hippocampus, and prefrontal cortex. AIMS neuroscience. vol 8. issue 2. 2021-05-19. PMID:33709024. |
neurocircuit differences between memory traces of persistent hypoactivity and freezing following fear conditioning among the amygdala, hippocampus, and prefrontal cortex. |
2021-05-19 |
2023-08-13 |
rat |
| Umer Javed Butt, Imam Hassouna, Laura Fernandez Garcia-Agudo, Agnes A Steixner-Kumar, Constanze Depp, Nadine Barnkothe, Matthias R Zillmann, Anja Ronnenberg, Viktoria Bonet, Sandra Goebbels, Klaus-Armin Nave, Hannelore Ehrenreic. CaMKIIα Expressing Neurons to Report Activity-Related Endogenous Hypoxia upon Motor-Cognitive Challenge. International journal of molecular sciences. vol 22. issue 6. 2021-05-12. PMID:33804598. |
in contrast, fear conditioning as hippocampal stimulus was likely too short-lived to provoke neuronal hypoxia. |
2021-05-12 |
2023-08-13 |
mouse |
| J D White, C M Urbano, J O Taylor, J L Peterman, M Cooksey, M Eimerbrink, M D Eriksson, B G Cooper, M J Chumley, G W Boeh. Intraventricular murine Aβ infusion elicits hippocampal inflammation and disrupts the consolidation, but not retrieval, of conditioned fear in C57BL6/J mice. Behavioural brain research. vol 378. 2021-04-29. PMID:31622640. |
intraventricular murine aβ infusion elicits hippocampal inflammation and disrupts the consolidation, but not retrieval, of conditioned fear in c57bl6/j mice. |
2021-04-29 |
2023-08-13 |
mouse |
| Isabelle C Ridderbusch, Yunbo Yang, Heike Weber, Andreas Reif, Sabine Herterich, Andreas Ströhle, Bettina Pfleiderer, Volker Arolt, Hans-Ulrich Wittchen, Ulrike Lueken, Tilo Kircher, Benjamin Straub. Neural correlates of NOS1 ex1f-VNTR allelic variation in panic disorder and agoraphobia during fear conditioning and extinction in fMRI. NeuroImage. Clinical. vol 27. 2021-03-08. PMID:32361414. |
in humans, the short (s) allele of a functional promotor polymorphism of nos1 (nos1 ex1f-vntr) has been shown to be associated with higher anxiety and altered fear conditioning in healthy subjects in the amygdala and hippocampus (amy/hipp). |
2021-03-08 |
2023-08-13 |
human |
| Hanna Yousuf, Vanessa L Ehlers, Megha Sehgal, Chenghui Song, James R Moye. Modulation of intrinsic excitability as a function of learning within the fear conditioning circuit. Neurobiology of learning and memory. vol 167. 2021-01-22. PMID:31821881. |
after fear conditioning, intrinsic excitability changes are evident in brain regions that are a critical part of the fear circuit, including the amygdala, hippocampus, retrosplenial cortex, and prefrontal cortex. |
2021-01-22 |
2023-08-13 |
Not clear |
| Chun Hui J Park, Despina E Ganella, Christina J Perry, Jee Hyun Ki. Dissociated roles of dorsal and ventral hippocampus in recall and extinction of conditioned fear in male and female juvenile rats. Experimental neurology. vol 329. 2020-12-24. PMID:32283056. |
dissociated roles of dorsal and ventral hippocampus in recall and extinction of conditioned fear in male and female juvenile rats. |
2020-12-24 |
2023-08-13 |
human |
| Linna Zhang, Danni Feng, Hong Tao, Xiangyan DE, Qing Chang, Qikuan H. Increased stathmin expression strengthens fear conditioning in epileptic rats. Biomedical reports. vol 3. issue 1. 2020-10-01. PMID:25469242. |
fear conditioning slightly increased the expression of stathmin, whereas epilepsy with fear conditioning increased it significantly in the hippocampus, insular cortex and hypothalamus. |
2020-10-01 |
2023-08-13 |
rat |
| Yang Zhang, Rong Ding, Shanshan Wang, Zhiyun Ren, Lingyan Xu, Xunle Zhang, Jiahui Zhao, Yu Ding, Yu Wu, Yuesong Gon. Effect of intraperitoneal or intracerebroventricular injection of streptozotocin on learning and memory in mice. Experimental and therapeutic medicine. vol 16. issue 3. 2020-10-01. PMID:30186480. |
following morris water maze (mwm) test and fear-conditioning test, cerebral cortex and hippocampus tissues were collected and the levels of psd95 and shank3 proteins in these tissues were measured by western blot analysis. |
2020-10-01 |
2023-08-13 |
mouse |
| Nicholas Chaaya, Angela Jacques, Arnauld Belmer, Kate Beecher, Syed A Ali, Fatemeh Chehrehasa, Andrew R Battle, Luke R Johnson, Selena E Bartlet. Contextual Fear Conditioning Alter Microglia Number and Morphology in the Rat Dorsal Hippocampus. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:31139053. |
the unpaired fear conditioning procedure (whereby non-reinforced and non-overlapping auditory tones were provided at random intervals during conditioning), despite producing equivalent levels of fear as the standard procedure, did not alter microglia, bdnf or pcreb number in any dorsal hippocampus or lateral amygdala brain regions. |
2020-10-01 |
2023-08-13 |
rat |
| Cuiyu Xiao, Yun Liu, Jian Xu, Xiong Gan, Zhongju Xia. Septal and Hippocampal Neurons Contribute to Auditory Relay and Fear Conditioning. Frontiers in cellular neuroscience. vol 12. 2020-09-30. PMID:29713265. |
septal and hippocampal neurons contribute to auditory relay and fear conditioning. |
2020-09-30 |
2023-08-13 |
Not clear |