| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Michael Bradshaw, Yoshi Kubota, Tobias Meyer, Howard Schulma. An ultrasensitive Ca2+/calmodulin-dependent protein kinase II-protein phosphatase 1 switch facilitates specificity in postsynaptic calcium signaling. Proceedings of the National Academy of Sciences of the United States of America. vol 100. issue 18. 2003-10-23. PMID:12928489. |
the switch-like response of a camkii-pp1 system suggests that camkii and pp1 may function together as a simple molecular device that specifically translates only strong ca2+ signals into all-or-none potentiation of individual hippocampal synapses. |
2003-10-23 |
2023-08-12 |
Not clear |
| Bjarte Håvik, Håvard Røkke, Kjetil Bårdsen, Svend Davanger, Clive R Bramha. Bursts of high-frequency stimulation trigger rapid delivery of pre-existing alpha-CaMKII mRNA to synapses: a mechanism in dendritic protein synthesis during long-term potentiation in adult awake rats. The European journal of neuroscience. vol 17. issue 12. 2003-09-24. PMID:12823475. |
messenger ribonucleic acid encoding the alpha-subunit of calcium/calmodulin-dependent protein kinase ii (camkii) is abundantly and constitutively expressed in dendrites of pyramidal and granule cell neurons of the adult hippocampus. |
2003-09-24 |
2023-08-12 |
rat |
| Charles C Fink, Karl-Ulrich Bayer, Jason W Myers, James E Ferrell, Howard Schulman, Tobias Meye. Selective regulation of neurite extension and synapse formation by the beta but not the alpha isoform of CaMKII. Neuron. vol 39. issue 2. 2003-08-18. PMID:12873385. |
here we show that ca2+/calmodulin-dependent protein kinase ii (camkii) regulates movement, extension, and branching of filopodia and fine dendrites as well as the number of synapses in hippocampal neurons. |
2003-08-18 |
2023-08-12 |
Not clear |
| P R Blanquet, J Mariani, P Dere. A calcium/calmodulin kinase pathway connects brain-derived neurotrophic factor to the cyclic AMP-responsive transcription factor in the rat hippocampus. Neuroscience. vol 118. issue 2. 2003-06-16. PMID:12699783. |
recently, using rat hippocampal slices, we found that bdnf induces activation of calcium/calmodulin-dependent protein kinase 2 (camkii), a critical mediator of synaptic plasticity. |
2003-06-16 |
2023-08-12 |
rat |
| Fanjie Meng, Jun Guo, Quanguang Zhang, Bo Song, Guangyi Zhan. Autophosphorylated calcium/calmodulin-dependent protein kinase II alpha (CaMKII alpha) reversibly targets to and phosphorylates N-methyl-D-aspartate receptor subunit 2B (NR2B) in cerebral ischemia and reperfusion in hippocampus of rats. Brain research. vol 967. issue 1-2. 2003-06-05. PMID:12650977. |
autophosphorylated calcium/calmodulin-dependent protein kinase ii alpha (camkii alpha) reversibly targets to and phosphorylates n-methyl-d-aspartate receptor subunit 2b (nr2b) in cerebral ischemia and reperfusion in hippocampus of rats. |
2003-06-05 |
2023-08-12 |
rat |
| Edwin J Weeber, Yong-Hui Jiang, Ype Elgersma, Andrew W Varga, Yarimar Carrasquillo, Sarah E Brown, Jill M Christian, Banefsheh Mirnikjoo, Alcino Silva, Arthur L Beaudet, J David Sweat. Derangements of hippocampal calcium/calmodulin-dependent protein kinase II in a mouse model for Angelman mental retardation syndrome. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 7. 2003-05-30. PMID:12684449. |
mutant animals exhibited a significant increase in hippocampal phospho-calcium/calmodulin-dependent protein kinase ii (camkii), specifically at sites thr(286) and thr(305), with no corresponding change in the levels of total camkii. |
2003-05-30 |
2023-08-12 |
mouse |
| Heather L Hinds, Ivan Goussakov, Kazu Nakazawa, Susumu Tonegawa, Vadim Y Bolshako. Essential function of alpha-calcium/calmodulin-dependent protein kinase II in neurotransmitter release at a glutamatergic central synapse. Proceedings of the National Academy of Sciences of the United States of America. vol 100. issue 7. 2003-05-22. PMID:12629219. |
to determine whether camkii regulates neurotransmitter release, we generated and analyzed knockout mice in which the dominant alpha-isoform of camkii was specifically deleted from the presynaptic side of the ca3-ca1 hippocampal synapse. |
2003-05-22 |
2023-08-12 |
mouse |
| Yuko Takagi, Norio Takagi, Shintaro Besshoh, Keiko Miyake-Takagi, Satoshi Take. Transient global ischemia enhances phosphorylation of the GluR1 subunit of the alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor in the hippocampal CA1 region in rats. Neuroscience letters. vol 341. issue 1. 2003-05-20. PMID:12676337. |
the results suggest that an activated camkii may phosphorylate ser831 of glur1 and a consequent phosphorylation of glur1 may be related to pathogenic events occurring in the vulnerable subfield of the hippocampus after transient global ischemia. |
2003-05-20 |
2023-08-12 |
rat |
| German Szapiro, Monica R M Vianna, James L McGaugh, Jorge H Medina, Ivan Izquierd. The role of NMDA glutamate receptors, PKA, MAPK, and CAMKII in the hippocampus in extinction of conditioned fear. Hippocampus. vol 13. issue 1. 2003-04-18. PMID:12625457. |
the role of nmda glutamate receptors, pka, mapk, and camkii in the hippocampus in extinction of conditioned fear. |
2003-04-18 |
2023-08-12 |
Not clear |
| Thomas Blank, Ingrid Nijholt, Stefanie Vollstaedt, Joachim Spies. The corticotropin-releasing factor receptor 1 antagonist CP-154,526 reverses stress-induced learning deficits in mice. Behavioural brain research. vol 138. issue 2. 2003-04-15. PMID:12527451. |
when animals were pretreated with cp-154,526 before immobilization, the amount of hippocampal autophosphorylated camkii was elevated. |
2003-04-15 |
2023-08-12 |
mouse |
| E Miyamoto, K Fukunaga, Y Takeuchi, H Yamamoto, J Kasahara, Jie Li. [Calcium signaling and brain functions]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 120. issue 1. 2003-04-01. PMID:12491766. |
activation of camkii and iv and mitogen-activated protein kinase (mapk) was observed during long-term potentiation (ltp) induction in the ca1 area of hippocampus. |
2003-04-01 |
2023-08-12 |
Not clear |
| Hiroki Yasuda, Alison L Barth, David Stellwagen, Robert C Malenk. A developmental switch in the signaling cascades for LTP induction. Nature neuroscience. vol 6. issue 1. 2003-03-07. PMID:12469130. |
we report here that, unlike ltp in the more mature ca1 region of the hippocampus, ltp in neonatal rodent hippocampus (<9 postnatal days, camkii). |
2003-03-07 |
2023-08-12 |
Not clear |
| J-H Tao-Cheng, L Vinade, L D Pozzo-Miller, T S Reese, A Dosemec. Calcium/calmodulin-dependent protein kinase II clusters in adult rat hippocampal slices. Neuroscience. vol 115. issue 2. 2003-01-23. PMID:12421609. |
we have previously reported the formation of calcium/calmodulin-dependent protein kinase ii (camkii) clusters approximately 110 nm in diameter in hippocampal neurons in culture and in the intact adult brain, under conditions that simulate ischemic stress and increase [ca(2+)](i) [dosemeci et al. |
2003-01-23 |
2023-08-12 |
rat |
| J-H Tao-Cheng, L Vinade, L D Pozzo-Miller, T S Reese, A Dosemec. Calcium/calmodulin-dependent protein kinase II clusters in adult rat hippocampal slices. Neuroscience. vol 115. issue 2. 2003-01-23. PMID:12421609. |
these observations suggest that ischemia-like conditions that prevail during the dissection of brain tissue for the preparation of hippocampal slices could lead to the formation of camkii clusters. |
2003-01-23 |
2023-08-12 |
rat |
| J-H Tao-Cheng, L Vinade, L D Pozzo-Miller, T S Reese, A Dosemec. Calcium/calmodulin-dependent protein kinase II clusters in adult rat hippocampal slices. Neuroscience. vol 115. issue 2. 2003-01-23. PMID:12421609. |
we now show by pre-embedding immuno-electron microscopy that, indeed, camkii clusters are present in the ca1 pyramidal neurons in hippocampal slices from adult rats fixed immediately after dissection, and that the number of camkii clusters increases with the delay time between decapitation and fixation. |
2003-01-23 |
2023-08-12 |
rat |
| J-H Tao-Cheng, L Vinade, L D Pozzo-Miller, T S Reese, A Dosemec. Calcium/calmodulin-dependent protein kinase II clusters in adult rat hippocampal slices. Neuroscience. vol 115. issue 2. 2003-01-23. PMID:12421609. |
on the other hand, when dissociated hippocampal neurons in primary culture are exposed to the same depolarizing conditions, only approximately 25% of neurons exhibit camkii clusters, indicating a difference in the susceptibility of the neurons in culture and in acute slices to excitatory stimuli. |
2003-01-23 |
2023-08-12 |
rat |
| J-H Tao-Cheng, L Vinade, L D Pozzo-Miller, T S Reese, A Dosemec. Calcium/calmodulin-dependent protein kinase II clusters in adult rat hippocampal slices. Neuroscience. vol 115. issue 2. 2003-01-23. PMID:12421609. |
altogether these observations indicate that the effect of camkii clustering should be considered when interpreting experimental results obtained with hippocampal slices. |
2003-01-23 |
2023-08-12 |
rat |
| Fanjie Meng, Guangyi Zhan. Autophosphorylated calcium/calmodulin-dependent protein kinase II alpha induced by cerebral ischemia immediately targets and phosphorylates N-methyl-D-aspartate receptor subunit 2B (NR2B) in hippocampus of rats. Neuroscience letters. vol 333. issue 1. 2002-12-26. PMID:12401560. |
in this article, we investigated the autophosphorylation and translocation of calcium/calmodulin-dependent protein kinase ii alpha (camkii alpha) in hippocampus during global ischemia. |
2002-12-26 |
2023-08-12 |
rat |
| T Sawai, F Bernier, T Fukushima, T Hashimoto, H Ogura, Y Nishizaw. Estrogen induces a rapid increase of calcium-calmodulin-dependent protein kinase II activity in the hippocampus. Brain research. vol 950. issue 1-2. 2002-12-23. PMID:12231258. |
we show that estradiol benzoate activates camkii in a dose and time-dependent manner in mouse hippocampus after 30 min stimulation. |
2002-12-23 |
2023-08-12 |
mouse |
| T Sawai, F Bernier, T Fukushima, T Hashimoto, H Ogura, Y Nishizaw. Estrogen induces a rapid increase of calcium-calmodulin-dependent protein kinase II activity in the hippocampus. Brain research. vol 950. issue 1-2. 2002-12-23. PMID:12231258. |
these results suggest that estrogen action in the hippocampus is linked to camkii activation. |
2002-12-23 |
2023-08-12 |
mouse |