| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Irena Smaga, Bartosz Pomierny, Weronika Krzyżanowska, Lucyna Pomierny-Chamioło, Joanna Miszkiel, Ewa Niedzielska, Agata Ogórka, Małgorzata Fili. N-acetylcysteine possesses antidepressant-like activity through reduction of oxidative stress: behavioral and biochemical analyses in rats. Progress in neuro-psychopharmacology & biological psychiatry. vol 39. issue 2. 2013-03-19. PMID:22820675. |
on the other hand, chronic administration of nac and imi resulted in a significant increase in cellular antioxidant mechanisms (sod activity) that reversed the effects of bulb in the frontal cortex, hippocampus and striatum. |
2013-03-19 |
2023-08-12 |
rat |
| Julie M Brooks, Michelle L Pershing, Morten S Thomsen, Jens D Mikkelsen, Martin Sarter, John P Brun. Transient inactivation of the neonatal ventral hippocampus impairs attentional set-shifting behavior: reversal with an α7 nicotinic agonist. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 11. 2013-02-26. PMID:22781844. |
cognitive deficits represent a core symptom cluster in schizophrenia that are thought to reflect developmental dysregulations within a neural system involving the ventral hippocampus (vh), nucleus accumbens (nac), and prefrontal cortex (pfc). |
2013-02-26 |
2023-08-12 |
rat |
| Andrew F MacAskill, Justin P Little, John M Cassel, Adam G Carte. Subcellular connectivity underlies pathway-specific signaling in the nucleus accumbens. Nature neuroscience. vol 15. issue 12. 2013-01-29. PMID:23143514. |
we found that medium spiny neurons (msns) in both the direct and indirect pathways of the mouse nucleus accumbens (nac) receive inputs from the cortex, thalamus and hippocampus. |
2013-01-29 |
2023-08-12 |
mouse |
| Jonathan P Britt, Faiza Benaliouad, Ross A McDevitt, Garret D Stuber, Roy A Wise, Antonello Bonc. Synaptic and behavioral profile of multiple glutamatergic inputs to the nucleus accumbens. Neuron. vol 76. issue 4. 2013-01-24. PMID:23177963. |
here, we compared the innervation patterns and synaptic properties of ventral hippocampus, basolateral amygdala, and prefrontal cortex input to the nac. |
2013-01-24 |
2023-08-12 |
Not clear |
| Jonathan P Britt, Faiza Benaliouad, Ross A McDevitt, Garret D Stuber, Roy A Wise, Antonello Bonc. Synaptic and behavioral profile of multiple glutamatergic inputs to the nucleus accumbens. Neuron. vol 76. issue 4. 2013-01-24. PMID:23177963. |
ventral hippocampal input was found to be uniquely localized to the medial nac shell, where it was predominant and selectively potentiated after cocaine exposure. |
2013-01-24 |
2023-08-12 |
Not clear |
| Michelle A Erickson, Kim Hansen, William A Bank. Inflammation-induced dysfunction of the low-density lipoprotein receptor-related protein-1 at the blood-brain barrier: protection by the antioxidant N-acetylcysteine. Brain, behavior, and immunity. vol 26. issue 7. 2013-01-17. PMID:22809665. |
we also found that nac pre-administration resulted in lower blood levels of the cytokines and chemokines interferon-γ, interleukin-10, ccl2, ccl4, and ccl5, but only lowered ccl4 in the cerebral cortex and hippocampus. |
2013-01-17 |
2023-08-12 |
Not clear |
| Viviana Trezza, Ruth Damsteegt, Antonia Manduca, Stefania Petrosino, Linda W M Van Kerkhof, R Jeroen Pasterkamp, Yeping Zhou, Patrizia Campolongo, Vincenzo Cuomo, Vincenzo Di Marzo, Louk J M J Vanderschure. Endocannabinoids in amygdala and nucleus accumbens mediate social play reward in adolescent rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 43. 2013-01-07. PMID:23100412. |
social play increased levels of the endocannabinoid anandamide in the amygdala and nucleus accumbens (nac), but not in prefrontal cortex or hippocampus of 4- to 5-week-old male wistar rats. |
2013-01-07 |
2023-08-12 |
rat |
| Yonas B Keleta, Joe L Martine. Brain Circuits of Methamphetamine Place Reinforcement Learning: The Role of the Hippocampus-VTA Loop. Brain and behavior. vol 2. issue 2. 2012-08-23. PMID:22574281. |
vta is primary source of dopamine (da) to the nucleus accumbens (nac) and the ventral hippocampus (vhc). |
2012-08-23 |
2023-08-12 |
rat |
| Yonas B Keleta, Joe L Martine. Brain Circuits of Methamphetamine Place Reinforcement Learning: The Role of the Hippocampus-VTA Loop. Brain and behavior. vol 2. issue 2. 2012-08-23. PMID:22574281. |
therefore, we tested the involvement of the hippocampus in reinforcement learning by studying conditioned place preference (cpp) learning by sequentially conditioning each of the three nuclei in either the bottom-up order of conditioning; vta, then vhc, finally nac, or the top-down order; vhc, then vta, finally nac. |
2012-08-23 |
2023-08-12 |
rat |
| Zhengtao Hu, Yi Deng, Chunyan Hu, Pengchi Deng, Qian Bu, Guangyan Yan, Jiaqing Zhou, Xue Shao, Jinxuan Zhao, Yan Li, Ruiming Zhu, Youzhi Xu, Yinglan Zhao, Xiaobo Ce. ¹H NMR-based metabonomic analysis of brain in rats of morphine dependence and withdrawal intervention. Behavioural brain research. vol 231. issue 1. 2012-08-20. PMID:22391120. |
in the present study, the metabolic changes in brain hippocampus, nucleus accumbens (nac), prefrontal cortex (pfc) and striatum of rats with morphine dependence and withdrawal intervention were explored by using ¹h nuclear magnetic resonance coupled with principal component analysis, partial least squares and orthogonal signal correction analysis. |
2012-08-20 |
2023-08-12 |
rat |
| Zhengtao Hu, Yi Deng, Chunyan Hu, Pengchi Deng, Qian Bu, Guangyan Yan, Jiaqing Zhou, Xue Shao, Jinxuan Zhao, Yan Li, Ruiming Zhu, Youzhi Xu, Yinglan Zhao, Xiaobo Ce. ¹H NMR-based metabonomic analysis of brain in rats of morphine dependence and withdrawal intervention. Behavioural brain research. vol 231. issue 1. 2012-08-20. PMID:22391120. |
we found that the concentrations of neurotransmitters including glutamate, glutamine and gamma-aminobutyric acid changed differentially in hippocampus, nac, pfc and striatum after repeated morphine treatment. |
2012-08-20 |
2023-08-12 |
rat |
| Milene C Carvalho, Caio M Moreira, Janaína M Zanoveli, Marcus L Brandã. Central, but not basolateral, amygdala involvement in the anxiolytic-like effects of midazolam in rats in the elevated plus maze. Journal of psychopharmacology (Oxford, England). vol 26. issue 4. 2012-08-17. PMID:21148026. |
in the present study, we ethopharmacologically analyzed the behavior of rats subjected to the epm and the tissue content of the monoamines dopamine (da) and serotonin (5-ht) and their metabolites in the nucleus accumbens (nac), dorsal hippocampus (dh), and dorsal striatum (ds) of animals injected with saline or midazolam (20 and 30 nmol/0.2 µl) into the bla or cea. |
2012-08-17 |
2023-08-12 |
rat |
| Julie M Brooks, Martin Sarter, John P Brun. Transient inactivation of the neonatal ventral hippocampus permanently disrupts the mesolimbic regulation of prefrontal cholinergic transmission: implications for schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 12. 2012-08-08. PMID:21814184. |
intra-nac nmda evoked prefrontal ach release in rats receiving ttx, on pd7, into the dorsal hippocampus (dh), basolateral amygdala, or nac. |
2012-08-08 |
2023-08-12 |
rat |
| Anthony Falluel-Morel, Lulu Lin, Katie Sokolowski, Elizabeth McCandlish, Brian Buckley, Emanuel DiCicco-Bloo. N-acetyl cysteine treatment reduces mercury-induced neurotoxicity in the developing rat hippocampus. Journal of neuroscience research. vol 90. issue 4. 2012-06-12. PMID:22420031. |
moreover, the intermediate-term decrease in hippocampal cell number provoked by mehg was fully blocked by nac. |
2012-06-12 |
2023-08-12 |
rat |
| Ya-Hsin Hsiao, Jinn-Rung Kuo, Shun-Hua Chen, Po-Wu Gea. Amelioration of social isolation-triggered onset of early Alzheimer's disease-related cognitive deficit by N-acetylcysteine in a transgenic mouse model. Neurobiology of disease. vol 45. issue 3. 2012-06-07. PMID:22227002. |
here we show that n-acetylcysteine (nac), an anti-oxidant, is capable of preventing social isolation-induced accelerated impairment of contextual fear memory and rundown of hippocampal ltp in 3-month old app/ps1 mice. |
2012-06-07 |
2023-08-12 |
mouse |
| Ya-Hsin Hsiao, Jinn-Rung Kuo, Shun-Hua Chen, Po-Wu Gea. Amelioration of social isolation-triggered onset of early Alzheimer's disease-related cognitive deficit by N-acetylcysteine in a transgenic mouse model. Neurobiology of disease. vol 45. issue 3. 2012-06-07. PMID:22227002. |
increased hippocampal levels of γ-secretase activity, aβ-40 and aβ-42 seen in the isolated app/ps1 mice were reduced by chronic treatment of nac. |
2012-06-07 |
2023-08-12 |
mouse |
| Paolo Tucci, Maria Grazia Morgese, Marilena Colaianna, Margherita Zotti, Stefania Schiavone, Vincenzo Cuomo, Luigia Trabac. Neurochemical consequence of steroid abuse: stanozolol-induced monoaminergic changes. Steroids. vol 77. issue 3. 2012-05-11. PMID:22197661. |
twenty-four hours after last injection, changes of dopamine (da) and relative metabolite levels, homovanilic acid (hva) and 3,4-dihydroxy phenylacetic acid (dopac), serotonin (5-ht) and its metabolite levels, 5-hydroxy indolacetic acid (5-hiaa), and noradrenaline (na) amount were investigated in prefrontal cortex (pfc), nucleus accumbens (nac), striatum (str) and hippocampus (hipp). |
2012-05-11 |
2023-08-12 |
rat |
| Roberto I Melendez, Jacqueline F McGinty, Peter W Kalivas, Howard C Becke. Brain region-specific gene expression changes after chronic intermittent ethanol exposure and early withdrawal in C57BL/6J mice. Addiction biology. vol 17. issue 2. 2012-05-08. PMID:21812870. |
high-density oligonucleotide microarrays (affymetrix 430a 2.0, affymetrix, santa clara, ca, usa) and bioinformatics analysis were used to characterize gene expression and function in the prefrontal cortex (pfc), hippocampus (hpc) and nucleus accumbens (nac) of c57bl/6j mice (jackson laboratories, bar harbor, me, usa). |
2012-05-08 |
2023-08-12 |
mouse |
| Edit Papp, Zsolt Borhegyi, Ryohei Tomioka, Kathleen S Rockland, István Mody, Tamás F Freun. Glutamatergic input from specific sources influences the nucleus accumbens-ventral pallidum information flow. Brain structure & function. vol 217. issue 1. 2012-04-23. PMID:21643647. |
the excitatory inputs governing this system converge in the nac from the prefrontal cortex (pfc), ventral hippocampus (vhc), midline and intralaminar thalamus (th) and basolateral nucleus of the amygdala (bla). |
2012-04-23 |
2023-08-12 |
Not clear |
| Kristen A Horner, Yamiece E Gilbert, Erika S Nobl. Differential regulation of 5-HT2A receptor mRNA expression following withdrawal from a chronic escalating dose regimen of D-amphetamine. Brain research. vol 1390. 2012-03-07. PMID:21420940. |
the goal of the current study was to determine the effects of chronic, escalating doses of d-amphetamine (d-amph) and withdrawal on the expression of 5-ht(2a) receptors in the cortex, caudate putamen, nac and hippocampus of rat brain. |
2012-03-07 |
2023-08-12 |
rat |