| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E-M Kim, J J Elliot, P Hobson, E O'Har. Effects of intrahippocampal NAC 61-95 injections on memory in the rat and attenuation with vitamin E. Progress in neuro-psychopharmacology & biological psychiatry. vol 33. issue 6. 2010-04-12. PMID:19410626. |
two groups were injected bilaterally into the dorsal hippocampus with aggregated nac(61-95) (5 microl suspension), and two groups were injected bilaterally into the dorsal hippocampus with sterile water (5 microl). |
2010-04-12 |
2023-08-12 |
human |
| Matthew J Fell, Jason S Katner, Bryan G Johnson, Albert Khilevich, Jeffrey M Schkeryantz, Kenneth W Perry, Kjell A Svensso. Activation of metabotropic glutamate (mGlu)2 receptors suppresses histamine release in limbic brain regions following acute ketamine challenge. Neuropharmacology. vol 58. issue 3. 2010-04-07. PMID:19951716. |
ketamine (25 mg/kg) increased ha in the medial prefrontal cortex (mpfc), ventral hippocampus (vhipp) and the nucleus accumbens (nac) shell. |
2010-04-07 |
2023-08-12 |
rat |
| Agata Adamczyk, Grzegorz A Czapski, Anna Kaźmierczak, Joanna B Strosznajde. Effect of N-methyl-D-aspartate (NMDA) receptor antagonists on alpha-synuclein-evoked neuronal nitric oxide synthase activation in the rat brain. Pharmacological reports : PR. vol 61. issue 6. 2010-03-30. PMID:20081243. |
the present study examined the effect of alpha-synuclein and the nac peptide on nitric oxide synthase (nos) activity in rat brain cortical and hippocampal slices using a radiochemical technique. |
2010-03-30 |
2023-08-12 |
rat |
| Eugene O'Hare, Jennifer J Elliott, Peter Hobson, Shane M O'Mara, David Spanswick, Eun-Mee Ki. Bilateral intrahippocampal NAC61-95 effects on behavior and moderation with L-NAME treatment. Neuroscience research. vol 66. issue 2. 2010-03-02. PMID:19913060. |
this study evaluated the effect of n((omega))-nitro-l-arginine methyl ester (l-name), a nitric oxide synthase inhibitor, on the behavior of rats bilaterally injected into the ca3 area of the dorsal hippocampus with aggregated nac(61-95). |
2010-03-02 |
2023-08-12 |
rat |
| Eugene O'Hare, Jennifer J Elliott, Peter Hobson, Shane M O'Mara, David Spanswick, Eun-Mee Ki. Bilateral intrahippocampal NAC61-95 effects on behavior and moderation with L-NAME treatment. Neuroscience research. vol 66. issue 2. 2010-03-02. PMID:19913060. |
when responding was stable, 12 rats were injected bilaterally into the ca3 area of the hippocampus with aggregated nac(61-95) (5muicro per side; concentration 10(-4)m), the remaining 12 rats were similarly injected with sterile water (sw), six of the nac(61-95) injected rats and six of the sw injected rats were treated for 90 days post-injections with 0.05mg/ml l-name in drinking water available ad libitum. |
2010-03-02 |
2023-08-12 |
rat |
| Gustavo S Pacheco, Jordana P Panatto, Diego A Fagundes, Giselli Scaini, Cintia Bassani, Isabela C Jeremias, Gislaine T Rezin, Larissa Constantino, Felipe Dal-Pizzol, Emilio L Strec. Brain creatine kinase activity is inhibited after hepatic failure induced by carbon tetrachloride or acetaminophen. Metabolic brain disease. vol 24. issue 3. 2009-12-30. PMID:19688255. |
the administration of nac plus dfx reversed the inhibition of ck activity caused by carbon tetrachloride in cerebellum and by acetaminophen in cerebellum and hippocampus. |
2009-12-30 |
2023-08-12 |
human |
| Ulises M Ricoy, Joe L Martine. Local hippocampal methamphetamine-induced reinforcement. Frontiers in behavioral neuroscience. vol 3. 2009-12-16. PMID:19949457. |
here, the focus is on the hippocampus which has been largely ignored in the addiction literature as compared to the nucleus accumbens (nac), ventral tegmental area (vta), and prefrontal cortex (pfc). |
2009-12-16 |
2023-08-12 |
rat |
| Jingyi Ma, L Stan Leun. Kindled seizure in the prefrontal cortex activated behavioral hyperactivity and increase in accumbens gamma oscillations through the hippocampus. Behavioural brain research. vol 206. issue 1. 2009-12-09. PMID:19744527. |
after partial kindling (11+/-2 ads) of the pfc, the pfc-ad propagated into the hippocampus and nucleus accumbens (nac) and postictal hyperactivity lasted > 5 min. |
2009-12-09 |
2023-08-12 |
Not clear |
| Jingyi Ma, L Stan Leun. Kindled seizure in the prefrontal cortex activated behavioral hyperactivity and increase in accumbens gamma oscillations through the hippocampus. Behavioural brain research. vol 206. issue 1. 2009-12-09. PMID:19744527. |
a single ad in hippocampal ca1 also induced > 5 min of postictal hyperactivity and increased gamma oscillations in the nac and the pfc, with a transient increase in hippocampus-nac gamma coherence occurring 2-3 min after a hippocampal ad. |
2009-12-09 |
2023-08-12 |
Not clear |
| Feng Shao, Jian Jin, Qingxuan Meng, Mei Liu, Xi Xie, Wenjuan Lin, Weiwen Wan. Pubertal isolation alters latent inhibition and DA in nucleus accumbens of adult rats. Physiology & behavior. vol 98. issue 3. 2009-10-27. PMID:19527740. |
after the behavioral test, dopamine (da) levels were measured in the medial prefrontal cortex (mpfc), nucleus accumbens (nac), caudate-putamen (cpu), and the hippocampus (hip). |
2009-10-27 |
2023-08-12 |
rat |
| Yuan-Yuan Hou, Bin Lu, Mu Li, Yao Liu, Jie Chen, Zhi-Qiang Chi, Jing-Gen Li. Involvement of actin rearrangements within the amygdala and the dorsal hippocampus in aversive memories of drug withdrawal in acute morphine-dependent rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 39. 2009-10-13. PMID:19793983. |
we found that lesions of the amygdala or dorsal hippocampus (dh) but not nucleus accumbens (nac) impaired conditioned place aversion (cpa) of acute morphine-dependent rats. |
2009-10-13 |
2023-08-12 |
rat |
| Alberto Del Arco, Francisco Mor. Neurotransmitters and prefrontal cortex-limbic system interactions: implications for plasticity and psychiatric disorders. Journal of neural transmission (Vienna, Austria : 1996). vol 116. issue 8. 2009-09-24. PMID:19475335. |
the pfc sends glutamatergic outputs to limbic areas such as the hippocampus and amygdala which in turn modulate the activity of the nucleus accumbens (nac). |
2009-09-24 |
2023-08-12 |
Not clear |
| Alberto Del Arco, Francisco Mor. Neurotransmitters and prefrontal cortex-limbic system interactions: implications for plasticity and psychiatric disorders. Journal of neural transmission (Vienna, Austria : 1996). vol 116. issue 8. 2009-09-24. PMID:19475335. |
dopamine and acetylcholine neurons in the brainstem and basal forebrain/septal areas, which send outputs to nac, hippocampus and amygdala, are also regulated by pfc glutamatergic projections, and seem to be of special relevance in modulating motor, emotional and mnemonic functions. |
2009-09-24 |
2023-08-12 |
Not clear |
| Frank I Tarazi, Yong Kee Choi, Matthew Gardner, Erik H F Wong, Brian Henry, Mohammed Shahi. Asenapine exerts distinctive regional effects on ionotropic glutamate receptor subtypes in rat brain. Synapse (New York, N.Y.). vol 63. issue 5. 2009-06-17. PMID:19177511. |
brain sections were collected from the medial prefrontal cortex (mpfc), dorsolateral frontal cortex, caudate putamen (cpu), nucleus accumbens (nac), and hippocampus (hip), and processed for in vitro receptor autoradiography. |
2009-06-17 |
2023-08-12 |
human |
| Kristen A Horner, Erika S Noble, Edward C Lauterbac. Differential regulation of prodynophin, c-fos, and serotonin transporter mRNA following withdrawal from a chronic, escalating dose regimen of D-amphetamine. Synapse (New York, N.Y.). vol 63. issue 4. 2009-04-08. PMID:19116947. |
following 24 h of withdrawal, there was an increase in pd and c-fos mrna expression in the cpu and nucleus accumbens (nac), and a decrease in pd and c-fos expression in hippocampus and amygdala. |
2009-04-08 |
2023-08-12 |
rat |
| Mei Huang, Zhu Li, Jin Dai, Mohammed Shahid, Erik H F Wong, Herbert Y Meltze. Asenapine increases dopamine, norepinephrine, and acetylcholine efflux in the rat medial prefrontal cortex and hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 12. 2009-02-20. PMID:18418367. |
atypical antipsychotic drugs, which are more potent direct acting antagonists of brain serotonin (5-ht)(2a) than dopamine (da) d(2) receptors, preferentially enhance da and acetylcholine (ach) efflux in the rat medial prefrontal cortex (mpfc) and hippocampus (hip), compared with the nucleus accumbens (nac). |
2009-02-20 |
2023-08-12 |
rat |
| Soon-Eng Ta. Roles of hippocampal NMDA receptors and nucleus accumbens D1 receptors in the amphetamine-produced conditioned place preference in rats. Brain research bulletin. vol 77. issue 6. 2008-12-29. PMID:18929625. |
there are glutamatergic projections from the hippocampus to the nucleus accumbens (nac), which regulate da transmission in this structure. |
2008-12-29 |
2023-08-12 |
rat |
| Soon-Eng Ta. Roles of hippocampal NMDA receptors and nucleus accumbens D1 receptors in the amphetamine-produced conditioned place preference in rats. Brain research bulletin. vol 77. issue 6. 2008-12-29. PMID:18929625. |
this study investigates the roles of hippocampal n-methyl-d-aspartate (nmda) glutamate receptors and nac type 1 dopamine receptor (d1) in amphetamine-produced conditioned place preference (amph-cpp) in rats. |
2008-12-29 |
2023-08-12 |
rat |
| Soon-Eng Ta. Roles of hippocampal NMDA receptors and nucleus accumbens D1 receptors in the amphetamine-produced conditioned place preference in rats. Brain research bulletin. vol 77. issue 6. 2008-12-29. PMID:18929625. |
moreover, inactivation of hippocampal area (dorsal hippocampus or ventral hippocampus) impaired amph-cpp, but its effect was diminished by the activation of d1 receptors in accumbal region (nac core or nac shell). |
2008-12-29 |
2023-08-12 |
rat |
| Pornnarin Taepavarapruk, John G Howland, Soyon Ahn, Anthony G Phillip. Neural circuits engaged in ventral hippocampal modulation of dopamine function in medial prefrontal cortex and ventral striatum. Brain structure & function. vol 213. issue 1-2. 2008-12-02. PMID:18288486. |
using microdialysis in freely moving rats, we provide evidence in the present study that brief stimulation (20 hz, 10 s) of the ventral hippocampus potently increases da efflux in the mpfc, nac, and ventral tegmental area for 30-40 min. |
2008-12-02 |
2023-08-12 |
rat |