| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pardis Asgari, Ghraer McKinney, Travis E Hodges, Cheryl M McCormic. Social Instability Stress in Adolescence and Social Interaction in Female Rats. Neuroscience. vol 477. 2021-11-09. PMID:34619317. |
nevertheless, when tested in adolescence at p47 (and not at p71), ss female rats had higher corticosterone release during the social interaction test than did ctl rats, and they exhibited a different pattern of neural activation as measured by immunoreactivity to the protein products of zif268 and c-fos (ss < ctl in medial prefrontal cortex and ss > ctl in hippocampus), and reduced oxytocin immunoreactivity in the paraventricular nucleus of the hypothalamus than did ctl rats. |
2021-11-09 |
2023-08-13 |
rat |
| Giorgia Boero, Ryan E Tyler, Caroline A Todd, Todd K O'Buckley, Irina Balan, Joyce Besheer, A Leslie Morro. (3α,5α)3-hydroxypregnan-20-one (3α,5α-THP) regulation of hypothalamic and extrahypothalamic corticotropin releasing factor (CRF): Sexual dimorphism and brain region specificity in Sprague Dawley rats. Neuropharmacology. vol 186. 2021-11-05. PMID:33460689. |
crf neurons are found mainly in the hypothalamus, but crf positive cells and crf1 receptors are also found in extrahypothalamic structures, including amygdala (cea), hippocampus, nac and vta. |
2021-11-05 |
2023-08-13 |
rat |
| E A Sekste, A A Lebedev, E R Bychkov, M I Airapetov, K E Gramota, I Yu Thyssen, P D Shabano. [Increase in the level of orexin receptor 1 (OX1R) mRNA in the brain structures of rats prone to impulsivity in behavior]. Biomeditsinskaia khimiia. vol 67. issue 5. 2021-11-05. PMID:34730554. |
the aim of this work was to study the level of orexin receptor mrna in the hypothalamus, hippocampus, and prefrontal cortex of rats prone to impulsivity in behavior in a model for studying the elements of gambling addiction (a variant of the iowa gambling task test). |
2021-11-05 |
2023-08-13 |
rat |
| E A Sekste, A A Lebedev, E R Bychkov, M I Airapetov, K E Gramota, I Yu Thyssen, P D Shabano. [Increase in the level of orexin receptor 1 (OX1R) mRNA in the brain structures of rats prone to impulsivity in behavior]. Biomeditsinskaia khimiia. vol 67. issue 5. 2021-11-05. PMID:34730554. |
the expression of the ox1r gene was higher in the hypothalamus by 122% and in the hippocampus by 149% in rats that preferred to receive a high reward, but with a low probability as compared with a group of animals that preferred a low level of reinforcement, but with a 100% probability. |
2021-11-05 |
2023-08-13 |
rat |
| E A Sekste, A A Lebedev, E R Bychkov, M I Airapetov, K E Gramota, I Yu Thyssen, P D Shabano. [Increase in the level of orexin receptor 1 (OX1R) mRNA in the brain structures of rats prone to impulsivity in behavior]. Biomeditsinskaia khimiia. vol 67. issue 5. 2021-11-05. PMID:34730554. |
the level of ox2r mrna insignificantly changed in the hypothalamus, hippocampus, and prefrontal cortex of rats prone to impulsivity in behavior. |
2021-11-05 |
2023-08-13 |
rat |
| E A Sekste, A A Lebedev, E R Bychkov, M I Airapetov, K E Gramota, I Yu Thyssen, P D Shabano. [Increase in the level of orexin receptor 1 (OX1R) mRNA in the brain structures of rats prone to impulsivity in behavior]. Biomeditsinskaia khimiia. vol 67. issue 5. 2021-11-05. PMID:34730554. |
the data indicate involvement of ox1r in the hypothalamus and hippocampus in mechanisms mediating impulsive behavior and the choice of the significance of positive reinforcement in terms of its varying strength and probability. |
2021-11-05 |
2023-08-13 |
rat |
| Shamseddin Ahmadi, Mohammad Zobeiri, Shiva Mohammadi Talvar, Kayvan Masoudi, Amir Khanizad, Shima Fotouhi, Steven Bradbur. Differential expression of H19, BC1, MIAT1, and MALAT1 long non-coding RNAs within key brain reward regions after repeated morphine treatment. Behavioural brain research. vol 414. 2021-11-04. PMID:34302875. |
expression of h19, bc1, miat1, and malat1 lncrnas was determined from the midbrain, striatum, hypothalamus, prefrontal cortex (pfc), and hippocampus by real-time pcr on day 8 of the repeated injections. |
2021-11-04 |
2023-08-13 |
rat |
| Shamseddin Ahmadi, Mohammad Zobeiri, Shiva Mohammadi Talvar, Kayvan Masoudi, Amir Khanizad, Shima Fotouhi, Steven Bradbur. Differential expression of H19, BC1, MIAT1, and MALAT1 long non-coding RNAs within key brain reward regions after repeated morphine treatment. Behavioural brain research. vol 414. 2021-11-04. PMID:34302875. |
the bc1 expression significantly altered in the midbrain, hypothalamus, and hippocampus, but not in the striatum and pfc after repeated morphine treatment. |
2021-11-04 |
2023-08-13 |
rat |
| Shamseddin Ahmadi, Mohammad Zobeiri, Shiva Mohammadi Talvar, Kayvan Masoudi, Amir Khanizad, Shima Fotouhi, Steven Bradbur. Differential expression of H19, BC1, MIAT1, and MALAT1 long non-coding RNAs within key brain reward regions after repeated morphine treatment. Behavioural brain research. vol 414. 2021-11-04. PMID:34302875. |
the miat1 and malat1 expression site-specifically altered in the midbrain, hypothalamus, and striatum; however, no significant changes were detected in their expression in the pfc and hippocampus after repeated morphine treatment. |
2021-11-04 |
2023-08-13 |
rat |
| Janine Karina Hideko Alfenas Horita, Maria Carolina Machado da Silva, Carolina Zaniboni Ferrari, Erica Leandro Marciano Vieira, Fabricio A Moreira, Antônio Carlos Pinheiro de Oliveira, Helton José Rei. Evaluation of Brain Cytokines and the Level of Brain-Derived Neurotrophic Factor in an Inflammatory Model of Depression. Neuroimmunomodulation. vol 27. issue 2. 2021-10-28. PMID:33176302. |
inflammatory processes are likely involved in its pathophysiology, but the underlying mechanisms have remained uncertain.here, we used the model of systemic lipopolysaccharide (lps) injection to test the hypothesis that depressive-like behaviors occur along with changes in the levels of cytokines and brain-derived neurotrophic factor (bdnf) in the hippocampus (hc), prefrontal cortex (pfc), and hypothalamus (ht), and can be prevented by dexamethasone administration. |
2021-10-28 |
2023-08-13 |
Not clear |
| Giada Amodeo, Benedetta Verduci, Patrizia Sartori, Patrizia Procacci, Vincenzo Conte, Gianfranco Balboni, Paola Sacerdote, Silvia Franch. The Antagonism of the Prokineticin System Counteracts Bortezomib Induced Side Effects: Focus on Mood Alterations. International journal of molecular sciences. vol 22. issue 19. 2021-10-28. PMID:34638592. |
the presence of mood alterations is related to the presence of neuroinflammation and pk system activation in prefrontal cortex, hippocampus and hypothalamus with high levels of pk2 and pkr2 receptor, il-6 and tnf-α, tlr4 and an upregulation of glial markers. |
2021-10-28 |
2023-08-13 |
mouse |
| Annakarina Mundorf, Jennifer Koch, Nadja Kubitza, Selina C Wagner, Michaela Schmidt, Peter Gass, Nadja Freun. Morc1 as a potential new target gene in mood regulation: when and where to find in the brain. Experimental brain research. vol 239. issue 10. 2021-10-26. PMID:34331083. |
furthermore, morc1 mrna is present in many important brain areas of mood regulation like the medial prefrontal cortex, the nucleus accumbens, the hippocampus, the hypothalamus, and the amygdala. |
2021-10-26 |
2023-08-13 |
human |
| Junlong Li, Pingya He, Jian Zhang, Ning L. Orcinol glucoside improves the depressive-like behaviors of perimenopausal depression mice through modulating activity of hypothalamic-pituitary-adrenal/ovary axis and activating BDNF- TrkB-CREB signaling pathway. Phytotherapy research : PTR. vol 35. issue 10. 2021-10-26. PMID:34382261. |
meanwhile, og reversed the hyperactivity of hypothalamic-pituitary-adrenal (hpa) axis as evidenced by decreased cort and acth in serum, reduced as well as the mrna and protein expression of corticotropin-releasing hormone (crh) in hypothalamus and hippocampus. |
2021-10-26 |
2023-08-13 |
mouse |
| Stanislava Bukatova, Emese Renczes, Alexandra Reichova, Johan Filo, Anna Sadlonova, Boris Mravec, Daniela Ostatnikova, Jan Bakos, Zuzana Bacov. Shank3 Deficiency is Associated With Altered Profile of Neurotransmission Markers in Pups and Adult Mice. Neurochemical research. vol 46. issue 12. 2021-10-21. PMID:34453663. |
our research found enhanced expression of serotonin transporter and choline acetyltransferase in the hippocampus and hypothalamus in shank3-deficient pups. |
2021-10-21 |
2023-08-13 |
mouse |
| Fumiko Obata, Tom Obri. Distribution of Gb(3) Immunoreactivity in the Mouse Central Nervous System. Toxins. vol 2. issue 8. 2021-10-20. PMID:20725533. |
the immunoreactive neurons are in olfactory bulbs, cerebral cortex, hippocampus, striatum, amygdala, thalamus, hypothalamus, cerebellum, and medulla oblongata. |
2021-10-20 |
2023-08-12 |
mouse |
| Qiong Wu, Bin Wang, Michael Ntim, Xuan Zhang, Xue-Yan Na, Yu-Hui Yuan, Xue-Fei Wu, Jin-Yi Yang, Shao L. SRC-1 Deficiency Increases Susceptibility of Mice to Depressive-Like Behavior After Exposure to CUMS. Neurochemical research. vol 46. issue 7. 2021-10-18. PMID:33881662. |
src-1 is abundant in hippocampus and hypothalamus and is also related to some major risk factors for depression, implicated by its reduced expression after stress and its effect on hypothalamus-pituitary-adrenal gland axis function. |
2021-10-18 |
2023-08-13 |
mouse |
| Yanpo Si, Xiaohui Chen, Tao Guo, Wenjun Wei, Lili Wang, Fei Zhang, Xiaoya Sun, Mengqi Li. Comprehensive 16S rDNA Sequencing and LC-MS/MS-Based Metabolomics to Investigate Intestinal Flora and Metabolic Profiles of the Serum, Hypothalamus and Hippocampus in p‑Chlorophenylalanine-Induced Insomnia Rats Treated with Lilium brownie. Neurochemical research. 2021-10-18. PMID:34661797. |
it was also found that the most of metabolic phenotypes in serum, hypothalamus and hippocampus perturbed by pcpa were regulated towards normal after lb intervention, especially 5-hydroxy-l-tryptophan of the hypothalamus involving in 5-ht metabolism. |
2021-10-18 |
2023-08-13 |
rat |
| Yanpo Si, Xiaohui Chen, Tao Guo, Wenjun Wei, Lili Wang, Fei Zhang, Xiaoya Sun, Mengqi Li. Comprehensive 16S rDNA Sequencing and LC-MS/MS-Based Metabolomics to Investigate Intestinal Flora and Metabolic Profiles of the Serum, Hypothalamus and Hippocampus in p‑Chlorophenylalanine-Induced Insomnia Rats Treated with Lilium brownie. Neurochemical research. 2021-10-18. PMID:34661797. |
moreover, the arachidonic acid metabolism in serum, hypothalamus and hippocampus, and the serotonergic synapse in hypothalamus and hippocampus were the most fundamentally and significantly affected pathways after lb intervention. |
2021-10-18 |
2023-08-13 |
rat |
| R L Moretti, E N Dias, S G Kiel, M C M Augusto, P S Rodrigues, A C S Sampaio, L S Medeiros, M F M Martins, I B Suffredini, C V Cardoso, E F Bonda. Behavioral and morphological effects of resveratrol and curcumin in rats submitted to doxorubicin-induced cognitive impairment. Research in veterinary science. vol 140. 2021-10-15. PMID:34536813. |
dox-injected rats presented short-term and long-term memory impairments as seen in the nort at 3 and 24 h after habituation and increased gfap and iba1 expression, respectively, in astrocytes and microglia of the frontal cortex, hypothalamus and hippocampus. |
2021-10-15 |
2023-08-13 |
rat |
| Yongliang Pan, Qingqing Zhu, Xiaotong Wang, Jiaxin Chen, Boyuan Wen, Zhongshan Zhang, Zuoxin Wan. Agonistic behaviors and neuronal activation in sexually naïve female Mongolian gerbils. Behavioural brain research. vol 395. 2021-10-13. PMID:32798594. |
losers also had more fos-ir cells in the paraventricular nucleus of the hypothalamus (pvn), anterior medial (bstam) and anteriolateral (bstal) subnuclei of the bed nucleus of the stria terminalis (bst), and the ventral subnucleus of the lateral septum (lsv), as well as less fos-ir cells in the dentate gyrus of the hippocampus (dg), compared to the controls. |
2021-10-13 |
2023-08-13 |
Not clear |