| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Damira Avgustinovich, Anna Kovner, Elena Kashina, Natalia Shatskaya, Galina Vishnivetskaya, Natalia Bondar, Maria Lvov. The pathogenic potential of the combined action of chronic Opisthorchis felineus infection and repeated social defeat stress in C57BL/6 mice. International journal for parasitology. vol 51. issue 5. 2021-10-11. PMID:33378706. |
real-time pcr analysis showed that the expression of genes aif1 and il6 differed among the analysed brain regions (hippocampus, hypothalamus, and frontal cortex) and depended on the adverse factors applied. |
2021-10-11 |
2023-08-13 |
mouse |
| Damira Avgustinovich, Anna Kovner, Elena Kashina, Natalia Shatskaya, Galina Vishnivetskaya, Natalia Bondar, Maria Lvov. The pathogenic potential of the combined action of chronic Opisthorchis felineus infection and repeated social defeat stress in C57BL/6 mice. International journal for parasitology. vol 51. issue 5. 2021-10-11. PMID:33378706. |
in addition, among the brain regions, there was no consistent increase or decrease in these parameters when the two adverse treatments were combined: (i) in the hippocampus, there was upregulation of aif1 and no change in il6 expression; (ii) in the hypothalamus, expression levels of aif1 and il6 were not different from controls; and (iii) in the frontal cortex, aif1 expression did not change while il6 expression increased. |
2021-10-11 |
2023-08-13 |
mouse |
| Chen-Cheng Lin, Pao-Yun Cheng, Yia-Ping Li. Effects of early life social experience on fear extinction and related glucocorticoid profiles - behavioral and neurochemical approaches in a rat model of PTSD. Behavioural brain research. vol 391. 2021-10-05. PMID:32428628. |
neurochemically, plasma corticosterone levels and glucocorticoid receptor (gr), fk506-binding proteins 4 and 5 (fkbp4 and fkbp5) and early growth response-1 (egr-1) expression were measured in gr-abundant brain areas, including the hypothalamus, medial prefrontal cortex, and hippocampus. |
2021-10-05 |
2023-08-13 |
rat |
| Chen-Cheng Lin, Pao-Yun Cheng, Yia-Ping Li. Effects of early life social experience on fear extinction and related glucocorticoid profiles - behavioral and neurochemical approaches in a rat model of PTSD. Behavioural brain research. vol 391. 2021-10-05. PMID:32428628. |
ir prevented the sps-impaired fear extinction retrieval ability and averted the sps-elevated expression of gr, fkbp4, and egr-1 in the hippocampus, whereas it did not change the sps-reduced plasma corticosterone levels and sps-enhanced gr activity in the mpfc and hypothalamus. |
2021-10-05 |
2023-08-13 |
rat |
| Xin Zhao, Alejandro N Rondón-Ortiz, Erika P Lima, Madeline Puracchio, Ryland C Roderick, Amanda C Kentne. Therapeutic efficacy of environmental enrichment on behavioral, endocrine, and synaptic alterations in an animal model of maternal immune activation. Brain, behavior, & immunity - health. vol 3. 2021-09-29. PMID:32368757. |
within the prefrontal cortex, hippocampus, amygdala, and hypothalamus, mia and ee altered the mrna expression of several genes associated with resiliency and synaptic plasticity in both sexes. |
2021-09-29 |
2023-08-13 |
human |
| Jéssica Fragoso, Gabriela Carvalho Jurema Santos, Helyson Thomaz da Silva, Emmanuelle Loizon, Viviane de Oliveira Nogueira Souza, Hubert Vidal, Rubem Carlos Araújo Guedes, João Henrique Costa-Silva, Raquel da Silva Aragão, Luciano Pirola, Carol Gois Leandr. Effects of maternal low-protein diet and spontaneous physical activity on the transcription of neurotrophic factors in the placenta and the brains of mothers and offspring rats. Journal of developmental origins of health and disease. vol 12. issue 3. 2021-09-23. PMID:32799949. |
this study quantified the gene expression of brain-derived neurotrophic factor (bdnf), neurothrophin 4, tyrosine kinase receptor b (trkb/ntrk2), insulin-like growth factor (igf-1), and insulin-like growth factor receptor (igf-1r) in the different areas of mother's brain (hypothalamus, hippocampus, and cortex), placenta, and fetus' brain of rats. |
2021-09-23 |
2023-08-13 |
rat |
| Jéssica Fragoso, Gabriela Carvalho Jurema Santos, Helyson Thomaz da Silva, Emmanuelle Loizon, Viviane de Oliveira Nogueira Souza, Hubert Vidal, Rubem Carlos Araújo Guedes, João Henrique Costa-Silva, Raquel da Silva Aragão, Luciano Pirola, Carol Gois Leandr. Effects of maternal low-protein diet and spontaneous physical activity on the transcription of neurotrophic factors in the placenta and the brains of mothers and offspring rats. Journal of developmental origins of health and disease. vol 12. issue 3. 2021-09-23. PMID:32799949. |
dams submitted to a lp diet during gestation showed upregulation of igf-1r and bdnf messenger rna in the hypothalamus, igf-1r and ntrk2 in the hippocampus, and bdnf, ntrk2, igf-1 and igf-1r in the cortex. |
2021-09-23 |
2023-08-13 |
rat |
| Jéssica Fragoso, Gabriela Carvalho Jurema Santos, Helyson Thomaz da Silva, Emmanuelle Loizon, Viviane de Oliveira Nogueira Souza, Hubert Vidal, Rubem Carlos Araújo Guedes, João Henrique Costa-Silva, Raquel da Silva Aragão, Luciano Pirola, Carol Gois Leandr. Effects of maternal low-protein diet and spontaneous physical activity on the transcription of neurotrophic factors in the placenta and the brains of mothers and offspring rats. Journal of developmental origins of health and disease. vol 12. issue 3. 2021-09-23. PMID:32799949. |
voluntary physical activity attenuated the effects of lp diet on igf-1r in the hypothalamus, igf-1r and ntrk2 in the hippocampus, igf-1 in the placenta, and ntrk2 in the fetus' brain. |
2021-09-23 |
2023-08-13 |
rat |
| Zhixin Fan, Jie Chen, Ling Li, Hanzhang Wang, Xiayu Gong, Hanfang Xu, Lili Wu, Can Ya. Environmental enrichment modulates HPA axis reprogramming in adult male rats exposed to early adolescent stress. Neuroscience research. vol 172. 2021-09-21. PMID:33901553. |
in this study, we used the single prolonged stress (sps) paradigm to explore the long-term effects of early adolescent stress on behavior, hpa axis activity, as well as expression levels of the glucocorticoid receptor (gr), mineralocorticoid receptor (mr), corticotropin-releasing hormone receptor 1 (crf1r) and crf2r in the hypothalamus and hippocampus. |
2021-09-21 |
2023-08-13 |
rat |
| Weikang Cai, Xuemei Zhang, Thiago M Batista, Rubén García-Martín, Samir Softic, Guoxiao Wang, Alfred K Ramirez, Masahiro Konishi, Brian T O'Neill, Jong Hun Kim, Jason K Kim, C Ronald Kah. Peripheral Insulin Regulates a Broad Network of Gene Expression in Hypothalamus, Hippocampus, and Nucleus Accumbens. Diabetes. vol 70. issue 8. 2021-09-21. PMID:34031123. |
peripheral insulin regulates a broad network of gene expression in hypothalamus, hippocampus, and nucleus accumbens. |
2021-09-21 |
2023-08-13 |
mouse |
| Weikang Cai, Xuemei Zhang, Thiago M Batista, Rubén García-Martín, Samir Softic, Guoxiao Wang, Alfred K Ramirez, Masahiro Konishi, Brian T O'Neill, Jong Hun Kim, Jason K Kim, C Ronald Kah. Peripheral Insulin Regulates a Broad Network of Gene Expression in Hypothalamus, Hippocampus, and Nucleus Accumbens. Diabetes. vol 70. issue 8. 2021-09-21. PMID:34031123. |
insulin regulates distinct pathways in the hypothalamus (htm), hippocampus, and nucleus accumbens. |
2021-09-21 |
2023-08-13 |
mouse |
| Limei Zhang, Vito S Hernández, Mario A Zetter, Lee E Eide. VGLUT-VGAT expression delineates functionally specialised populations of vasopressin-containing neurones including a glutamatergic perforant path-projecting cell group to the hippocampus in rat and mouse brain. Journal of neuroendocrinology. vol 32. issue 4. 2021-09-08. PMID:31944441. |
we have previously identified avp-magnocellular neurones of rat hypothalamus that provide glutamatergic projections to the hippocampus, amygdala, lateral habenula and locus coeruleus. |
2021-09-08 |
2023-08-13 |
mouse |
| Paulina Wigner, Ewelina Synowiec, Piotr Czarny, Michal Bijak, Paweł Jóźwiak, Janusz Szemraj, Piotr Gruca, Mariusz Papp, Tomasz Śliwińsk. Effects of venlafaxine on the expression level and methylation status of genes involved in oxidative stress in rats exposed to a chronic mild stress. Journal of cellular and molecular medicine. vol 24. issue 10. 2021-09-07. PMID:32281745. |
after completion of both stress conditions and drug administration, the mrna and protein expression of selected genes and the methylation status of their promoters were measured in peripheral mononuclear blood cells (pbmcs) and in brain structures (hippocampus, amygdala, hypothalamus, midbrain, cortex, basal ganglia) with the use of taqman gene expression assay, western blot and methylation-sensitive high-resolution melting techniques. |
2021-09-07 |
2023-08-13 |
human |
| Wen-Yu Lien, Yu-Ting Chen, Yi-Jhan Li, Jie-Kai Wu, Kuan-Lin Huang, Jian-Rong Lin, Shih-Ching Lin, Chia-Chun Hou, Horng-Dar Wang, Chia-Lin Wu, Shu-Yi Huang, Chih-Chiang Cha. Lifespan regulation in α/β posterior neurons of the fly mushroom bodies by Rab27. Aging cell. vol 19. issue 8. 2021-08-24. PMID:32627932. |
here, we show that the drosophila lifespan is modulated by rab27 functioning in a small subset of neurons of the mushroom bodies (mb), a brain structure that shares analogous functions with mammalian hippocampus and hypothalamus. |
2021-08-24 |
2023-08-13 |
drosophila_melanogaster |
| Ryan E Tyler, Benjamin Z S Weinberg, Dennis F Lovelock, Laura C Ornelas, Joyce Beshee. Exposure to the predator odor TMT induces early and late differential gene expression related to stress and excitatory synaptic function throughout the brain in male rats. Genes, brain, and behavior. vol 19. issue 8. 2021-08-17. PMID:32666635. |
gene expression analyses revealed upregulated fkbp5 6 hours post-tmt in the hypothalamus and dorsal hippocampus. |
2021-08-17 |
2023-08-13 |
rat |
| Francesca Zoratto, Clelia Buccheri, Romina Mura, Luisa Altabella, Marion Vanneste, Marie Villotte, Giovanni Laviola, Francois Dauphin, Eleni Paizanis, Walter Adriani, Rossella Canes. Anatomical and behavioral impact of a lentiviral tool tapping onto hippocampal serotonin reuptake in rats. Synapse (New York, N.Y.). vol 74. issue 4. 2021-08-10. PMID:31587367. |
while all rats had a widespread modification within dorsal/ventral striatum, amygdala, and hypothalamus, only the former subgroup showed an involvement of raphé medialis, while, for the latter subgroup, an increase of sert within hippocampus was unexpectedly caused. |
2021-08-10 |
2023-08-13 |
rat |
| Anna Brancato, Sara L M Lo Russo, Anna Sara Liberati, Cristiana Carbone, Silvia Zelli, Giovanni Laviola, Carla Cannizzaro, Walter Adrian. Social Interactions of Dat-Het Epi-Genotypes Differing for Maternal Origins: The Development of a New Preclinical Model of Socio-Sexual Apathy. Biomedicines. vol 9. issue 7. 2021-08-09. PMID:34356842. |
we assessed the expression of noradrenaline transporter (net) in prefrontal cortex, hippocampus and hypothalamus, finding differences between the two offspring. |
2021-08-09 |
2023-08-13 |
rat |
| Ling Shan, Rolf Fronczek, Gert Jan Lammers, Dick F Swaa. The tuberomamillary nucleus in neuropsychiatric disorders. Handbook of clinical neurology. vol 180. 2021-07-28. PMID:34225943. |
the histamine neurons in it synthesize histamine by means of the key enzyme histidine decarboxylase (hdc) and from the tmn, innervate a large number of brain areas, such as the cerebral cortex, hippocampus, amygdala as well as the thalamus, hypothalamus, and basal ganglia. |
2021-07-28 |
2023-08-13 |
Not clear |
| Kamil Ziarniak, Monika Dudek, Julia Matuszewska, Łukasz Bijoch, Marek Skrzypski, Jan Celichowski, Joanna H Sliwowsk. Two weeks of moderate intensity locomotor training increased corticosterone concentrations but did not alter the number of adropin-immunoreactive cells in the hippocampus of diabetic type 2 and control rats. Acta histochemica. vol 123. issue 5. 2021-07-16. PMID:34229193. |
we found that: 1) in dm2 animals, running decreased insulin and increased glucose concentrations; 2) in c rats, running decreased insulin concentrations and had no effect on glucose concentration in blood; 3) running increased corticosterone (cort) concentrations in dm2 and c rats; 4) adr-ir cells were detected in the hippocampus and adr-ir fibers in the arcuate nucleus of the hypothalamus, which is a novel location; 5) metabolic status and running, however, did not change number of these cells. |
2021-07-16 |
2023-08-13 |
rat |
| E P G Vazi, F Holanda, N A Santos, C V Cardoso, M F M Martins, E F Bonda. Short-term systemic methotrexate administration in rats induces astrogliosis and microgliosis. Research in veterinary science. vol 138. 2021-07-08. PMID:34091228. |
on the 5th day, brain samples were collected for hematoxylin-eosin and luxol fast blue staining techniques, as well as for immunohistochemical staining for glial fibrillary acidic protein (gfap) expression in astrocytes and iba1 (ionized calcium binding adaptor molecule 1) for microglia in the frontal cortex, hippocampus, hypothalamus and molecular/granular layers of the cerebellum. |
2021-07-08 |
2023-08-13 |
rat |