| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hashan S M Jayarathne, Lucas K Debarba, Jacob J Jaboro, Brett C Ginsburg, Richard A Miller, Marianna Sadagursk. Neuroprotective effects of Canagliflozin: Lessons from aged genetically diverse UM-HET3 mice. Aging cell. 2022-06-16. PMID:35707855. |
here, we show that cana treatment significantly improved central insulin sensitivity in the hypothalamus and the hippocampus of 30-month-old male mice. |
2022-06-16 |
2023-08-14 |
mouse |
| Hanmu Guo, Lexin Zheng, Heng Xu, Qiuyu Pang, Zhiyang Ren, Yuan Gao, Tao Wan. Neurobiological Links between Stress, Brain Injury, and Disease. Oxidative medicine and cellular longevity. vol 2022. 2022-06-06. PMID:35663199. |
this review summarizes various stress models and their applications and then discusses the effects and mechanisms of stress on key brain regions-including the hippocampus, hypothalamus, amygdala, and prefrontal cortex-and in brain injuries and diseases-including alzheimer's disease, stroke, traumatic brain injury, and epilepsy. |
2022-06-06 |
2023-08-14 |
Not clear |
| Yang Yang, Peirong Xu, Jie Liu, Mindie Zhao, Wei Cong, Wanwan Han, Deyun Wang, Ruqian Zha. Constant light exposure in early life induces m 6A-mediated inhibition of IGF gene family in the chicken. Journal of animal science. 2022-05-31. PMID:35641104. |
constant light exposure in early life reduced mrna expression of igf gene family, including mrna expression of igf1, igf2 and igf2 binding proteins (igf2bps), in the hippocampus, hypothalamus and liver of chickens at both 7 d and 21 d of age. |
2022-05-31 |
2023-08-13 |
chicken |
| Alena Kalinina, Diane Lagac. Single-Cell and Single-Nucleus RNAseq Analysis of Adult Neurogenesis. Cells. vol 11. issue 10. 2022-05-28. PMID:35626670. |
this review summarizes 33 published studies in the field of adult neurogenesis that have used sc- or sn-rnaseq methods to answer questions about the three main regions that host adult neural stem cells (nscs): the subventricular zone (svz), the dentate gyrus (dg) of the hippocampus, and the hypothalamus. |
2022-05-28 |
2023-08-13 |
Not clear |
| Chen-Cheng Lin, Pao-Yun Cheng, Michael Hsiao, Yia-Ping Li. Effects of RU486 in Treatment of Traumatic Stress-Induced Glucocorticoid Dysregulation and Fear-Related Abnormalities: Early versus Late Intervention. International journal of molecular sciences. vol 23. issue 10. 2022-05-28. PMID:35628305. |
neurochemically, the expressions of gr, fk506-binding proteins 4 and 5 (fkbp4 and fkbp5), and early growth response-1 (egr-1) were assessed in the hippocampus, medial prefrontal cortex (mpfc), amygdala, and hypothalamus, together with the level of plasma corticosterone. |
2022-05-28 |
2023-08-13 |
rat |
| Chen-Cheng Lin, Pao-Yun Cheng, Michael Hsiao, Yia-Ping Li. Effects of RU486 in Treatment of Traumatic Stress-Induced Glucocorticoid Dysregulation and Fear-Related Abnormalities: Early versus Late Intervention. International journal of molecular sciences. vol 23. issue 10. 2022-05-28. PMID:35628305. |
early ru486 administration following sps also increased the fkbp5 level in the hippocampus and hypothalamus. |
2022-05-28 |
2023-08-13 |
rat |
| Chen-Cheng Lin, Pao-Yun Cheng, Michael Hsiao, Yia-Ping Li. Effects of RU486 in Treatment of Traumatic Stress-Induced Glucocorticoid Dysregulation and Fear-Related Abnormalities: Early versus Late Intervention. International journal of molecular sciences. vol 23. issue 10. 2022-05-28. PMID:35628305. |
finally, both early and late ru486 administration inhibited the elevated hippocampal fkbp4 level and hypothalamus gr level in the sps rats. |
2022-05-28 |
2023-08-13 |
rat |
| Stefan Fritze, Geva A Brandt, Katharina M Kubera, Mike M Schmitgen, Georg Northoff, Lena S Geiger-Primo, Heike Tost, Andreas Meyer-Lindenberg, Robert C Wolf, Dusan Hirja. Structural alterations of amygdala and hypothalamus contribute to catatonia. Schizophrenia research. 2022-05-21. PMID:35597738. |
this potentially serious omission could explain why putative contributions of limbic system structures, such as amygdala, hippocampus or hypothalamus, to catatonia in schizophrenia spectrum disorders (ssd) have been scarcely investigated so far. |
2022-05-21 |
2023-08-13 |
Not clear |
| Stefan Fritze, Geva A Brandt, Katharina M Kubera, Mike M Schmitgen, Georg Northoff, Lena S Geiger-Primo, Heike Tost, Andreas Meyer-Lindenberg, Robert C Wolf, Dusan Hirja. Structural alterations of amygdala and hypothalamus contribute to catatonia. Schizophrenia research. 2022-05-21. PMID:35597738. |
to determine whether topographical alterations of the amygdala, hippocampus and hypothalamus contribute to catatonia in ssd patients, we conducted structural magnetic resonance imaging (mri) of ssd patients with (ssd-cat, n = 30) and without (ssd-noncat, n = 28) catatonia as defined by a northoff catatonia rating scale (ncrs) total score of ≥3 and =0, respectively, in comparison with healthy controls (n = 20). |
2022-05-21 |
2023-08-13 |
Not clear |
| Yosuke Yamawaki, Hitomi Kimura, Susumu Nagata, Koichiro Ozawa, Toru Hoso. Peripheral Immune Activation in Mice Elicits Unfolded Protein Responses Independent on MyD88 Pathway in the Liver but not the Hypothalamus and Hippocampus. Frontiers in physiology. vol 13. 2022-05-16. PMID:35574480. |
peripheral immune activation in mice elicits unfolded protein responses independent on myd88 pathway in the liver but not the hypothalamus and hippocampus. |
2022-05-16 |
2023-08-13 |
mouse |
| Ruixue Yu, Wenqing Yang, Dongmei Qi, Lili Gong, Chao Li, Yunlun Li, Haiqiang Jian. Targeted neurotransmitter metabolomics profiling of oleanolic acid in the treatment of spontaneously hypertensive rats. RSC advances. vol 9. issue 40. 2022-05-06. PMID:35514525. |
oa could effectively restore tyrosine metabolism in the striatum and hypothalamus, glutamate metabolism in the hippocampus, striatum and temporal lobe, cholinergic metabolism in the striatum, and histidine metabolism in the hypothalamus due to its inhibition of inflammatory reactions, structural damage of the neuronal cells, and increase in sedative activity. |
2022-05-06 |
2023-08-13 |
rat |
| Masae Furukawa, Hirobumi Tada, Jingshu Wang, Mitsuyoshi Yamada, Mie Kurosawa, Akiko Satoh, Noboru Ogiso, Yosuke Shikama, Kenji Matsushit. Molar loss induces hypothalamic and hippocampal astrogliosis in aged mice. Scientific reports. vol 12. issue 1. 2022-04-19. PMID:35437315. |
furthermore, in the hypothalamus and hippocampus of molar-extracted aged mice, the transcript-level expression of bdnf, rbfox3, and fos decreased, while that of cdkn2a and aif1 increased. |
2022-04-19 |
2023-08-13 |
mouse |
| Evgeniya V Efimova, Saveliy R Kuvarzin, Mikael S Mor, Nataliia V Katolikova, Taisiia S Shemiakova, Valeria Razenkova, Maria Ptukha, Alena A Kozlova, Ramilya Z Murtazina, Daria Smirnova, Aleksandr A Veshchitskii, Natalia S Merkulyeva, Anna B Volnova, Pavel E Musienko, Dmitrii E Korzhevskii, Evgeny A Budygin, Raul R Gainetdino. Trace Amine-Associated Receptor 2 Is Expressed in the Limbic Brain Areas and Is Involved in Dopamine Regulation and Adult Neurogenesis. Frontiers in behavioral neuroscience. vol 16. 2022-04-18. PMID:35431833. |
however, we also found staining in the deeper layers of the olfactory bulb and several brain regions, including the hippocampus, cerebellum, cortex, raphe nuclei, hypothalamus, and habenula, indicating that taar2 receptors are not only expressed in the olfactory system but are also present in the limbic brain areas that receive olfactory input. |
2022-04-18 |
2023-08-13 |
mouse |
| Alexandre Piccinini, Mariana Pacheco Oliveira, Mariella Reinol Silva, Gabriela Souza Bett, Isabel Borges Becker, Talita Farias Mendes, Daniéle Hendler Salla, Larissa Espindola Silva, Thais Ceresér Vilela, Fernanda Mendes Moraes, Diego Moterle, Adriani Paganini Damiani, Lígia Salvan Dagostin, Lariani Tamires Tietbohl, João Vitor Silvano Bittencourt, Erica Biehl, Tais Luise Denicol, Sandra Regina Bonfante, Vanessa Moraes Andrade, Paulo Cesar Lock Silveira, Josiane Somariva Prophiro, Gabriela Kozuchovski Ferreira, Fabricia Petronilho, Luiz Alberto Kanis, Gislaine Tezza Rezi. Effects of Ethanolic Extract of Cynara cardunculus (Artichoke) Leaves on Neuroinflammatory and Neurochemical Parameters in a Diet-Induced Mice Obesity Model. Neurochemical research. 2022-04-15. PMID:35426598. |
this study aimed to evaluate the effect of cynara cardunculus leaf ethanol extract on inflammatory and oxidative stress parameters in the hypothalamus, prefrontal cortex, hippocampus, striatum, cerebral cortex and liver of high-fat diet-induced obese mice. |
2022-04-15 |
2023-08-13 |
mouse |
| Rodolpho Pereira de Oliveira, José Simões de Andrade, Marianna Spina, João Vítor Chamon, Paulo Henrique Dias Silva, Ana Keyla Werder, Daniela Ortolani, Lucas de Santana Cardoso Thomaz, Simone Romariz, Daniel Araki Ribeiro, Beatriz Monteiro Longo, Regina Célia Spadari, Milena de Barros Viana, Liana Melo-Thomas, Isabel Cristina Céspedes, Regina Cláudia Barbosa da Silv. Clozapine prevented social interaction deficits and reduced c-Fos immunoreactivity expression in several brain areas of rats exposed to acute restraint stress. PloS one. vol 17. issue 3. 2022-03-03. PMID:35239670. |
in the present study, we evaluate the effect of acute restraint stress (15 min) of male wistar rats on social interaction measurements and c-fos immunoreactivity (c-fos-ir) expression, a marker of neuronal activity, in areas involved with the modulation of acute physical restraint in rats, i.e., the paraventricular nucleus of the hypothalamus (pvn), median raphe nucleus (mnr), medial prefrontal cortex (mpfc), cingulate prefrontal cortex (cpfc), nucleus accumbens (nac), hippocampus (ca3), lateral septum (ls) and medial amygdala (mea). |
2022-03-03 |
2023-08-13 |
rat |
| Rodolpho Pereira de Oliveira, José Simões de Andrade, Marianna Spina, João Vítor Chamon, Paulo Henrique Dias Silva, Ana Keyla Werder, Daniela Ortolani, Lucas de Santana Cardoso Thomaz, Simone Romariz, Daniel Araki Ribeiro, Beatriz Monteiro Longo, Regina Célia Spadari, Milena de Barros Viana, Liana Melo-Thomas, Isabel Cristina Céspedes, Regina Cláudia Barbosa da Silv. Clozapine prevented social interaction deficits and reduced c-Fos immunoreactivity expression in several brain areas of rats exposed to acute restraint stress. PloS one. vol 17. issue 3. 2022-03-03. PMID:35239670. |
we suggest that treatment with clozapine exerted a preventive effect in the social interaction deficit, at least in part, by blocking the effect of restraint stress in brain regions that are known to regulate the hpa-axis, including the cerebral cortex, hippocampus, hypothalamus, septum and amygdala. |
2022-03-03 |
2023-08-13 |
rat |
| Adriano Lama, Claudio Pirozzi, Ilenia Severi, Maria Grazia Morgese, Martina Senzacqua, Chiara Annunziata, Federica Comella, Filomena Del Piano, Stefania Schiavone, Stefania Petrosino, Maria Pina Mollica, Sabrina Diano, Luigia Trabace, Antonio Calignano, Antonio Giordano, Giuseppina Mattace Raso, Rosaria Mel. Palmitoylethanolamide dampens neuroinflammation and anxiety-like behavior in obese mice. Brain, behavior, and immunity. 2022-02-17. PMID:35176443. |
moreover, pea attenuated the immunoreactivity of iba-1 and gfap and reduced pro-inflammatory pathways and cytokine production in both the hypothalamus and hippocampus. |
2022-02-17 |
2023-08-13 |
mouse |
| Elisabeth K Goodman, Caitlin S Mitchell, Jonathan D Teo, Joanne M Gladding, Kirsten N Abbott, Neda Rafiei, Lei Zhang, Herbert Herzog, Denovan P Beg. The effect of insulin receptor deletion in neuropeptide Y neurons on hippocampal dependent cognitive function in aging mice. Journal of integrative neuroscience. vol 21. issue 1. 2022-02-15. PMID:35164442. |
insulin receptors are found in neuropeptide-y (npy) expressing neurons, which are abundant in the hypothalamus and hippocampus; regions involved in feeding behaviour and spatial memory, respectively. |
2022-02-15 |
2023-08-13 |
mouse |
| Cuihong Jia, W Drew Gill, Chiharu Lovins, Russell W Brown, Theo Hag. Female-specific role of ciliary neurotrophic factor in the medial amygdala in promoting stress responses. Neurobiology of stress. vol 17. 2022-02-11. PMID:35146079. |
cus did not alter cntf in the female hippocampus, hypothalamus and bed nucleus of stria terminalis. |
2022-02-11 |
2023-08-13 |
mouse |
| Mawj Mandwie, Jocelyn Karunia, Aram Niaz, Kevin A Keay, Giuseppe Musumeci, Claire Rennie, Kristine McGrath, Ghaith Al-Badri, Alessandro Castorin. Metformin Treatment Attenuates Brain Inflammation and Rescues PACAP/VIP Neuropeptide Alterations in Mice Fed a High-Fat Diet. International journal of molecular sciences. vol 22. issue 24. 2021-12-24. PMID:34948457. |
after 16 weeks, the proinflammatory profile, glial activation markers, and changes within the pi3k/akt intracellular pathway and the pacap/vip system were evaluated by real-time qpcr and/or western blot in the hypothalamus, hippocampus, prefrontal cortex, and amygdala. |
2021-12-24 |
2023-08-13 |
mouse |