| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Taibang Chen, Xiaoqing He, Jing Wang, Di Du, Yongqing X. NT-3 Combined with TGF-β Signaling Pathway Enhance the Repair of Spinal Cord Injury by Inhibiting Glial Scar Formation and Promoting Axonal Regeneration. Molecular biotechnology. 2023-06-15. PMID:37318740. |
nt-3 combined with tgf-β signaling pathway promotes astrocyte differentiation, reduces axon regeneration inhibitory molecules, apoptosis and glial scar formation, promotes axon regeneration, and improves spinal cord injury. |
2023-06-15 |
2023-08-14 |
mouse |
| Ai Takahashi, Hideaki Nakajima, Arisa Kubota, Shuji Watanabe, Akihiko Matsumin. Adipose-Derived Mesenchymal Stromal Cell Transplantation for Severe Spinal Cord Injury: Functional Improvement Supported by Angiogenesis and Neuroprotection. Cells. vol 12. issue 11. 2023-06-11. PMID:37296591. |
enhanced angiogenesis and decreased macrophage accumulation were observed at 2 weeks post-transplantation, whereas spinal cord cavity or scar size and axonal preservation were observed at 4 weeks. |
2023-06-11 |
2023-08-14 |
rat |
| Areez Shafqat, Ibrahem Albalkhi, Hamzah M Magableh, Tariq Saleh, Khaled Alkattan, Ahmed Yaqinuddi. Tackling the glial scar in spinal cord regeneration: new discoveries and future directions. Frontiers in cellular neuroscience. vol 17. 2023-06-09. PMID:37293626. |
tackling the glial scar in spinal cord regeneration: new discoveries and future directions. |
2023-06-09 |
2023-08-14 |
Not clear |
| Areez Shafqat, Ibrahem Albalkhi, Hamzah M Magableh, Tariq Saleh, Khaled Alkattan, Ahmed Yaqinuddi. Tackling the glial scar in spinal cord regeneration: new discoveries and future directions. Frontiers in cellular neuroscience. vol 17. 2023-06-09. PMID:37293626. |
axonal regeneration and functional recovery are poor after spinal cord injury (sci), typified by the formation of an injury scar. |
2023-06-09 |
2023-08-14 |
Not clear |
| Huitong Ruan, Yongfang Li, Cheng Wang, Yixu Jiang, Yulong Han, Yiwei Li, Dandan Zheng, Jing Ye, Gang Chen, Guo-Yuan Yang, Lianfu Deng, Ming Guo, Xingcai Zhang, Yaohui Tang, Wenguo Cu. Click chemistry extracellular vesicle/peptide/chemokine nanocarriers for treating central nervous system injuries. Acta pharmaceutica Sinica. B. vol 13. issue 5. 2023-05-30. PMID:37250158. |
central nervous system (cns) injuries, including stroke, traumatic brain injury, and spinal cord injury, are essential causes of death and long-term disability and are difficult to cure, mainly due to the limited neuron regeneration and the glial scar formation. |
2023-05-30 |
2023-08-14 |
Not clear |
| Bolin Zheng, Yijing He, Shuai Yin, Xu Zhu, Qing Zhao, Huiyi Yang, Zhaojie Wang, Rongrong Zhu, Liming Chen. Unresolved Excess Accumulation of Myelin-Derived Cholesterol Contributes to Scar Formation after Spinal Cord Injury. Research (Washington, D.C.). vol 6. 2023-05-24. PMID:37223476. |
unresolved excess accumulation of myelin-derived cholesterol contributes to scar formation after spinal cord injury. |
2023-05-24 |
2023-08-14 |
mouse |
| Bolin Zheng, Yijing He, Shuai Yin, Xu Zhu, Qing Zhao, Huiyi Yang, Zhaojie Wang, Rongrong Zhu, Liming Chen. Unresolved Excess Accumulation of Myelin-Derived Cholesterol Contributes to Scar Formation after Spinal Cord Injury. Research (Washington, D.C.). vol 6. 2023-05-24. PMID:37223476. |
however, the intrinsic mechanism of scar formation after spinal cord injury has not been fully elucidated. |
2023-05-24 |
2023-08-14 |
mouse |
| Tim Vangansewinkel, Stefanie Lemmens, Assia Tiane, Nathalie Geurts, Dearbhaile Dooley, Tim Vanmierlo, Gunnar Pejler, Sven Hendri. Therapeutic administration of mouse mast cell protease 6 improves functional recovery after traumatic spinal cord injury in mice by promoting remyelination and reducing glial scar formation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 37. issue 6. 2023-05-02. PMID:37130013. |
therapeutic administration of mouse mast cell protease 6 improves functional recovery after traumatic spinal cord injury in mice by promoting remyelination and reducing glial scar formation. |
2023-05-02 |
2023-08-14 |
mouse |
| Akihito Takeda, Mao Fujita, Kengo Funakosh. Distribution of 5HT Receptors During the Regeneration Process After Spinal Cord Transection in Goldfish. Journal of chemical neuroanatomy. 2023-04-29. PMID:37119932. |
spinal cord injury in teleosts leads to a fibrous scar, but axons sometimes spontaneously regenerate beyond the scar. |
2023-04-29 |
2023-08-14 |
Not clear |
| Arulkumar Nallakumarasamy, Mantu Jain, Sibasish Panigrahi, Auroshish Sahoo, Suprava Nai. Gelatin Sponge-induced Early Onset Quadriparesis after the Posterior Decompression for Cervical Myelopathy Due to Ossification of a Posterior Longitudinal Ligament - A Case Report. Journal of orthopaedic case reports. vol 12. issue 6. 2023-04-17. PMID:37065520. |
apart from their hemostatic properties, these are inert and provide form an inert membrane that prevents scar adhesions o vital structures such as the brain or spinal cord. |
2023-04-17 |
2023-08-14 |
Not clear |
| Tanner Clifford, Zachary Finkel, Brianna Rodriguez, Adelina Joseph, Li Ca. Current Advancements in Spinal Cord Injury Research-Glial Scar Formation and Neural Regeneration. Cells. vol 12. issue 6. 2023-03-29. PMID:36980193. |
current advancements in spinal cord injury research-glial scar formation and neural regeneration. |
2023-03-29 |
2023-08-14 |
Not clear |
| Liming Li, Heping Zheng, Xuepei Ma, Jie Bai, Shumin Ma, Zhuoyue Li, Chong Qi. Inhibition of Astrocytic Carbohydrate Sulfotransferase 15 Promotes Nerve Repair After Spinal Cord Injury via Mitigation of CSPG Mediated Axonal Inhibition. Cellular and molecular neurobiology. 2023-03-13. PMID:36913114. |
administration of the inhibitor in transected spinal cord tissues of rats effectively promotes motor functional restoration and nerve tissue regeneration by a mechanism related to the attenuation of inhibitory cspgs, glial scar formation and inflammatory responses. |
2023-03-13 |
2023-08-14 |
rat |
| Yiteng Li, Yihao Chen, Xuyang Hu, Fangru Ouyang, Jianjian Li, Jinxin Huang, Jianan Ye, Fangli Shan, Yong Luo, Shuisheng Yu, Ziyu Li, Fei Yao, Yanchang Liu, Yi Shi, Meige Zheng, Li Cheng, Juehua Jin. FTY720 hinders IFN-γ-mediated fibrotic scar formation and facilitates neurological recovery after spinal cord injury. Journal of neurotrauma. 2023-03-07. PMID:36879472. |
fty720 hinders ifn-γ-mediated fibrotic scar formation and facilitates neurological recovery after spinal cord injury. |
2023-03-07 |
2023-08-14 |
mouse |
| Yiteng Li, Yihao Chen, Xuyang Hu, Fangru Ouyang, Jianjian Li, Jinxin Huang, Jianan Ye, Fangli Shan, Yong Luo, Shuisheng Yu, Ziyu Li, Fei Yao, Yanchang Liu, Yi Shi, Meige Zheng, Li Cheng, Juehua Jin. FTY720 hinders IFN-γ-mediated fibrotic scar formation and facilitates neurological recovery after spinal cord injury. Journal of neurotrauma. 2023-03-07. PMID:36879472. |
following spinal cord injury (sci), fibrotic scar inhibits axon regeneration and impairs neurological function recovery. |
2023-03-07 |
2023-08-14 |
mouse |
| Yiteng Li, Yihao Chen, Xuyang Hu, Fangru Ouyang, Jianjian Li, Jinxin Huang, Jianan Ye, Fangli Shan, Yong Luo, Shuisheng Yu, Ziyu Li, Fei Yao, Yanchang Liu, Yi Shi, Meige Zheng, Li Cheng, Juehua Jin. FTY720 hinders IFN-γ-mediated fibrotic scar formation and facilitates neurological recovery after spinal cord injury. Journal of neurotrauma. 2023-03-07. PMID:36879472. |
furthermore, in situ injection of ifn-γ into the normal spinal cord resulted in fibrotic scar formation and inflammation response at 7 days post-injection. |
2023-03-07 |
2023-08-14 |
mouse |
| Sarah Walker, Tiago Santos-Ferreira, Karen Echeverr. A Reproducible Spinal Cord Crush Injury in the Regeneration-Permissive Axolotl. Methods in molecular biology (Clifton, N.J.). vol 2636. 2023-03-07. PMID:36881304. |
in contrast, humans respond to severe spinal cord injury by forming a glial scar, which prevents further damage but also inhibits any regenerative growth, resulting in loss of function caudal to the injury site. |
2023-03-07 |
2023-08-14 |
Not clear |
| Gentaro Ono, Kazu Kobayakawa, Hirokazu Saiwai, Tetsuya Tamaru, Hirotaka Iura, Yohei Haruta, Kazuki Kitade, Kei-Ichiro Iida, Ken-Ichi Kawaguchi, Yoshihiro Matsumoto, Makoto Tsuda, Tomohiko Tamura, Keiko Ozato, Kazuhide Inoue, Dai-Jiro Konno, Takeshi Maeda, Seiji Okada, Yasuharu Nakashim. Macrophages play a leading role in determining the direction of astrocytic migration in spinal cord injury via ADP-P2Y1R axis. Research square. 2023-02-15. PMID:36789440. |
after spinal cord injury (sci), inflammatory cells such as macrophages infiltrate the injured area, and astrocytes migrate, forming a glial scar around macrophages. |
2023-02-15 |
2023-08-14 |
mouse |
| Gentaro Ono, Kazu Kobayakawa, Hirokazu Saiwai, Tetsuya Tamaru, Hirotaka Iura, Yohei Haruta, Kazuki Kitade, Kei-Ichiro Iida, Ken-Ichi Kawaguchi, Yoshihiro Matsumoto, Makoto Tsuda, Tomohiko Tamura, Keiko Ozato, Kazuhide Inoue, Dai-Jiro Konno, Takeshi Maeda, Seiji Okada, Yasuharu Nakashim. Macrophages play a leading role in determining the direction of astrocytic migration in spinal cord injury via ADP-P2Y1R axis. Research square. 2023-02-15. PMID:36789440. |
chimeric mice with bone marrow lacking irf8, which controls macrophage centripetal migration after sci, showed widely scattered macrophages in injured spinal cord with the formation of a huge glial scar around the macrophages. |
2023-02-15 |
2023-08-14 |
mouse |
| Haichuan Peng, Yongkang Liu, Fengfeng Xiao, Limei Zhang, Wenting Li, Binghan Wang, Zhijian Weng, Yu Liu, Gang Che. Research progress of hydrogels as delivery systems and scaffolds in the treatment of secondary spinal cord injury. Frontiers in bioengineering and biotechnology. vol 11. 2023-02-06. PMID:36741755. |
secondary spinal cord injury (ssci) is the second stage of spinal cord injury (sci) and involves vasculature derangement, immune response, inflammatory response, and glial scar formation. |
2023-02-06 |
2023-08-14 |
Not clear |
| Shao-Ming Wang, Jung-Yu C Hsu, Chiung-Yuan Ko, Hsiang-En Wu, Yu-Wei Hsiao, Ju-Ming Wan. Astrocytic Cebpd Regulates Pentraxin 3 Expression to Promote Fibrotic Scar Formation After Spinal Cord Injury. Molecular neurobiology. 2023-01-12. PMID:36633805. |
astrocytic cebpd regulates pentraxin 3 expression to promote fibrotic scar formation after spinal cord injury. |
2023-01-12 |
2023-08-14 |
Not clear |