| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Byeong Gwan Song, Su Yeon Kwon, Jae Won Kyung, Eun Ji Roh, Hyemin Choi, Chang Su Lim, Seong Bae An, Seil Sohn, Inbo Ha. Synaptic Cell Adhesion Molecule 3 (SynCAM3) Deletion Promotes Recovery from Spinal Cord Injury by Limiting Glial Scar Formation. International journal of molecular sciences. vol 23. issue 11. 2022-06-10. PMID:35682897. |
synaptic cell adhesion molecule 3 (syncam3) deletion promotes recovery from spinal cord injury by limiting glial scar formation. |
2022-06-10 |
2023-08-14 |
mouse |
| Cong Xing, Zeyu Jia, Haodong Qu, Song Liu, Wang Jiang, Hao Zhong, Mi Zhou, Shibo Zhu, Guangzhi Ning, Shiqing Fen. Correlation Analysis Between Magnetic Resonance Imaging-Based Anatomical Assessment and Behavioral Outcome in a Rat Contusion Model of Chronic Thoracic Spinal Cord Injury. Frontiers in neuroscience. vol 16. 2022-05-09. PMID:35527814. |
moreover, with a moderate severity of sci in a contusion height of 25 mm, the smaller the la of the spinal cord measured on sagittal t2wi the better the functional performance, the smaller the cavity region and glial scar, the more spared the myelin, the higher the volatility, and the thicker the bladder wall. |
2022-05-09 |
2023-08-13 |
rat |
| Ayda Yari-Ilkhchi, Abbas Ebrahimi-Kalan, Mehdi Farhoudi, Mehrdad Mahka. Design of graphenic nanocomposites containing chitosan and polyethylene glycol for spinal cord injury improvement. RSC advances. vol 11. issue 33. 2022-04-28. PMID:35479903. |
during the acute phase, cascade responses involving cystic cavitation, fibrous glial scar formation, and myelin-associated dissuasive accumulation occur in the microenvironment of the spinal cord lesion. |
2022-04-28 |
2023-08-13 |
Not clear |
| Ziyu Li, Shuisheng Yu, Yanchang Liu, Xuyang Hu, Yiteng Li, Zhaoming Xiao, Yihao Chen, Dasheng Tian, Xinzhong Xu, Li Cheng, Meige Zheng, Juehua Jin. SU16f inhibits fibrotic scar formation and facilitates axon regeneration and locomotor function recovery after spinal cord injury by blocking the PDGFRβ pathway. Journal of neuroinflammation. vol 19. issue 1. 2022-04-17. PMID:35429978. |
su16f inhibits fibrotic scar formation and facilitates axon regeneration and locomotor function recovery after spinal cord injury by blocking the pdgfrβ pathway. |
2022-04-17 |
2023-08-13 |
Not clear |
| Ziyu Li, Shuisheng Yu, Yanchang Liu, Xuyang Hu, Yiteng Li, Zhaoming Xiao, Yihao Chen, Dasheng Tian, Xinzhong Xu, Li Cheng, Meige Zheng, Juehua Jin. SU16f inhibits fibrotic scar formation and facilitates axon regeneration and locomotor function recovery after spinal cord injury by blocking the PDGFRβ pathway. Journal of neuroinflammation. vol 19. issue 1. 2022-04-17. PMID:35429978. |
excessively deposited fibrotic scar after spinal cord injury (sci) inhibits axon regeneration. |
2022-04-17 |
2023-08-13 |
Not clear |
| Yangguang Ma, Penghui Li, Cheng Ju, Xiaoshuang Zuo, Xin Li, Tan Ding, Zhuowen Liang, Jiawei Zhang, Kun Li, Xuankang Wang, Zhijie Zhu, Zhihao Zhang, Zhiwen Song, Huilin Quan, Xueyu Hu, Zhe Wan. Photobiomodulation Attenuates Neurotoxic Polarization of Macrophages by Inhibiting the Notch1-HIF-1α/NF-κB Signalling Pathway in Mice With Spinal Cord Injury. Frontiers in immunology. vol 13. 2022-04-04. PMID:35371065. |
spinal cord injury (sci) is a catastrophic disease with a complex pathogenesis that includes inflammation, oxidative stress, and glial scar formation. |
2022-04-04 |
2023-08-13 |
mouse |
| Gang Zhou, Zhiyan Wang, Shiyuan Han, Xiaokun Chen, Zhimin Li, Xianghui Hu, Yongning Li, Jun Ga. Multifaceted Roles of cAMP Signaling in the Repair Process of Spinal Cord Injury and Related Combination Treatments. Frontiers in molecular neuroscience. vol 15. 2022-03-14. PMID:35283731. |
spinal cord injury (sci) results in multiple pathophysiological processes, including blood-spinal cord barrier disruption, hemorrhage/ischemia, oxidative stress, neuroinflammation, scar formation, and demyelination. |
2022-03-14 |
2023-08-13 |
Not clear |
| Yi Wang, Yanping Niu, Fanguo Lin, Peng Su, Liesong Chen, Dong Liu, Yongming Su. X-ray Irradiation Improves Neurological Function Recovery of Injured Spinal Cord by Inhibiting Inflammation and Glial Scar Formation. Journal of molecular neuroscience : MN. 2022-02-15. PMID:35165851. |
x-ray irradiation improves neurological function recovery of injured spinal cord by inhibiting inflammation and glial scar formation. |
2022-02-15 |
2023-08-13 |
Not clear |
| Yi Wang, Yanping Niu, Fanguo Lin, Peng Su, Liesong Chen, Dong Liu, Yongming Su. X-ray Irradiation Improves Neurological Function Recovery of Injured Spinal Cord by Inhibiting Inflammation and Glial Scar Formation. Journal of molecular neuroscience : MN. 2022-02-15. PMID:35165851. |
inflammation and glial scar formation influence the recovery of injured spinal cord. |
2022-02-15 |
2023-08-13 |
Not clear |
| Sonam Dolma, Kirti Adhikari, Teena Mamidi, Abhishek Roy, Zarna Pathak, Hemant Kuma. Ethamsylate attenuates mutilated secondary pathogenesis and exhibits a neuroprotective role in experimental model of spinal cord injury. Neuroscience. 2022-01-07. PMID:34995714. |
secondary pathogenesis, which initiates after the primary mechanical insult to the spinal cord, depicts a pivotal role in producing inflammation, lesion formation and ultimately causes fibrotic scar formation in the chronic period. |
2022-01-07 |
2023-08-13 |
Not clear |
| Sonam Dolma, Kirti Adhikari, Teena Mamidi, Abhishek Roy, Zarna Pathak, Hemant Kuma. Ethamsylate attenuates mutilated secondary pathogenesis and exhibits a neuroprotective role in experimental model of spinal cord injury. Neuroscience. 2022-01-07. PMID:34995714. |
therefore, we hypothesized that ethamsylate, by virtue of its anti-hemorrhagic activity, reduces hemorrhagic ischemia-induced neuronal apoptosis, maintains the blood spinal cord barrier integrity, and decreases secondary damage severity, thereby reduce the extent of fibrotic scar formation, and demonstrates a neuroprotective role in sci. |
2022-01-07 |
2023-08-13 |
Not clear |
| Gabrielle B Novais, Stefane Dos Santos, Robertta J R Santana, Rose N P Filho, John L S Cunha, Bruno S Lima, Adriano A S Araújo, Patricia Severino, Ricardo L C Albuquerque Júnior, Juliana C Cardoso, Eliana B Souto, Margarete Z Gome. Development of a New Formulation Based on In Situ Photopolymerized Polymer for the Treatment of Spinal Cord Injury. Polymers. vol 13. issue 24. 2021-12-28. PMID:34960825. |
spinal cord injury (sci) promotes a cascade of inflammatory events that are responsible for neuronal death and glial scar formation at the site of the injury, hindering tissue neuroregeneration. |
2021-12-28 |
2023-08-13 |
rat |
| Gaëtan Poulen, Sylvain Bartolami, Harun N Noristani, Florence E Perrin, Yannick N Gerbe. Unlike Brief Inhibition of Microglia Proliferation after Spinal Cord Injury, Long-Term Treatment Does Not Improve Motor Recovery. Brain sciences. vol 11. issue 12. 2021-12-24. PMID:34942945. |
microglia are major players in scar formation after an injury to the spinal cord. |
2021-12-24 |
2023-08-13 |
mouse |
| Qi-Ming Pang, Si-Yu Chen, Qi-Jing Xu, Sheng-Ping Fu, Yi-Chun Yang, Wang-Hui Zou, Meng Zhang, Juan Liu, Wei-Hong Wan, Jia-Chen Peng, Tao Zhan. Neuroinflammation and Scarring After Spinal Cord Injury: Therapeutic Roles of MSCs on Inflammation and Glial Scar. Frontiers in immunology. vol 12. 2021-12-20. PMID:34925326. |
neuroinflammation and scarring after spinal cord injury: therapeutic roles of mscs on inflammation and glial scar. |
2021-12-20 |
2023-08-13 |
Not clear |
| Qi-Ming Pang, Si-Yu Chen, Qi-Jing Xu, Sheng-Ping Fu, Yi-Chun Yang, Wang-Hui Zou, Meng Zhang, Juan Liu, Wei-Hong Wan, Jia-Chen Peng, Tao Zhan. Neuroinflammation and Scarring After Spinal Cord Injury: Therapeutic Roles of MSCs on Inflammation and Glial Scar. Frontiers in immunology. vol 12. 2021-12-20. PMID:34925326. |
here, we will review the effects of inflammatory response and glial scar formation in spinal cord injury and repair. |
2021-12-20 |
2023-08-13 |
Not clear |
| Qi-Lin Pan, Fei-Xiang Lin, Ning Liu, Rong-Chun Che. The role of aquaporin 4 (AQP4) in spinal cord injury. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 145. 2021-12-17. PMID:34915672. |
in particular, it plays an important role in secondary pathological processes (spinal cord edema, glial scar formation, and inflammatory response) after sci. |
2021-12-17 |
2023-08-13 |
mouse |
| Jamileh Saremi, Narges Mahmoodi, Mehdi Rasouli, Faezeh Esmaeili Ranjbar, Elham Lak Mazaheri, Marziyeh Akbari, Elham Hasanzadeh, Mahmoud Azam. Advanced approaches to regenerate spinal cord injury: The development of cell and tissue engineering therapy and combinational treatments. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 146. 2021-12-15. PMID:34906773. |
the reinnervation of spinal cord axons is hampered through a myriad of devices counting on the damaged myelin, inflammation, glial scar, and defective inhibitory molecules. |
2021-12-15 |
2023-08-13 |
Not clear |
| Jean-Christophe Perez, Yannick N Gerber, Florence E Perri. Dynamic Diversity of Glial Response Among Species in Spinal Cord Injury. Frontiers in aging neuroscience. vol 13. 2021-12-13. PMID:34899275. |
the glial scar that forms after traumatic spinal cord injury (sci) is mostly composed of microglia, ng2 glia, and astrocytes and plays dual roles in pathophysiological processes induced by the injury. |
2021-12-13 |
2023-08-13 |
Not clear |
| Florentia Papastefanak. Application of developmental principles for spinal cord repair after injury. The International journal of developmental biology. 2021-12-09. PMID:34549790. |
in this overview, some of the most recent and important studies are discussed that offer explicitly novel input from the field of development to the field of cns repair regarding the modification of the inhibitory environment of the injured spinal cord - majorly referring to the glial scar - the activation of endogenous cell populations such as ependymal stem cells and oligodendrocyte precursor cells, and the developmental transcriptional program that is transiently activated in neurons after injury. |
2021-12-09 |
2023-08-13 |
Not clear |
| Chao-Ming Da, Hai-Yang Liao, Yin-Shuan Deng, Guang-Hai Zhao, Lin Ma, Hai-Hong Zhan. Transcription Factor SP2 Regulates Ski-mediated Astrocyte Proliferation In Vitro. Neuroscience. vol 479. 2021-12-07. PMID:34687796. |
the upstream regulation mechanism of astrocyte proliferation was explored to further regulate the formation of glial scar in specific time and space after spinal cord injury. |
2021-12-07 |
2023-08-13 |
Not clear |