| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jenna Ollodart, Laiton R Steele, E Alfonso Romero-Sandoval, Roy E Strowd, Yusuke Shiozaw. Contributions of neuroimmune interactions to chemotherapy-induced peripheral neuropathy development and its prevention/therapy. Biochemical pharmacology. 2024-02-22. PMID:38387528. |
interestingly, monocytes/macrophages in dorsal root ganglia; microglia and astrocytes in spinal cord; mast cells in skin; and schwann cell near peripheral nerves have been identified as inducers of cipn behaviors, whereas t cells have been found to contribute to cipn resolution. |
2024-02-22 |
2024-02-25 |
Not clear |
| Hangyu Guo, Mingyu Du, Yang Yang, Xin Lin, Yufu Wang, Helin Li, Jiyu Ren, Wenbo Xu, Jinglong Yan, Nanxiang Wan. Sp1 regulates the M1 polarization of microglia through the HuR/NF-κB axis after spinal cord injury. Neuroscience. 2024-02-22. PMID:38387733. |
sp1 regulates the m1 polarization of microglia through the hur/nf-κb axis after spinal cord injury. |
2024-02-22 |
2024-02-25 |
mouse |
| Hangyu Guo, Mingyu Du, Yang Yang, Xin Lin, Yufu Wang, Helin Li, Jiyu Ren, Wenbo Xu, Jinglong Yan, Nanxiang Wan. Sp1 regulates the M1 polarization of microglia through the HuR/NF-κB axis after spinal cord injury. Neuroscience. 2024-02-22. PMID:38387733. |
the m1 polarization of microglia, followed by the production of pro-inflammatory mediators, hinders functional recovery after spinal cord injury (sci). |
2024-02-22 |
2024-02-25 |
mouse |
| Weixin Xie, Fan Li, Yi Han, Xiaoying Chi, Yi Qin, Fan Ye, Zhanchun Li, Jie Xia. Calcitonin gene-related peptide attenuated discogenic low back pain in rats possibly via inhibiting microglia activation. Heliyon. vol 10. issue 3. 2024-02-19. PMID:38371980. |
we observed obvious lumbar intervertebral disc degeneration and hyperalgesia at 12 weeks postoperation in dlbp group, with significantly activated microglia in the spinal cord. |
2024-02-19 |
2024-02-21 |
rat |
| Jiarui Wei, Tao Li, Shengyuan Lin, Bin Zhang, Xing L. Dihydrotestosterone reduces neuroinflammation in spinal cord injury through NF-κB and MAPK pathway. Cellular and molecular biology (Noisy-le-Grand, France). vol 70. issue 1. 2024-02-19. PMID:38372091. |
neuroinflammation induced by microglia following spinal cord injury (sci) leads to secondary neurologic injury. |
2024-02-19 |
2024-02-21 |
mouse |
| Jing Zhang, Die Hu, Liping Li, Di Qu, Weipeng Shi, Lei Xie, Qi Jiang, Haifeng Li, Tengbo Yu, Chao Qi, Haitao F. M2 Microglia-derived Exosomes Promote Spinal Cord Injury Recovery in Mice by Alleviating A1 Astrocyte Activation. Molecular neurobiology. 2024-02-17. PMID:38367135. |
m2 microglia transplantation has previously demonstrated beneficial effects on spinal cord injury (sci) by regulating neuroinflammation and enhancing neuronal survival. |
2024-02-17 |
2024-02-20 |
mouse |
| Xiaowen Liu, Huamei Cai, Liang Peng, Hongli Ma, Yun Yan, Weixia Li, Jing Zha. Microglial Nrf2/HO-1 signaling gates remifentanil-induced hyperalgesia via suppressing TRPV4-mediated M1 polarization. Free radical biology & medicine. 2024-02-13. PMID:38295888. |
this study aimed to unravel the role of spinal cord microglia, focusing on the nrf2/ho-1 signaling pathway and trpv4 channels in the development of rih. |
2024-02-13 |
2024-02-15 |
Not clear |
| Xiaowen Liu, Huamei Cai, Liang Peng, Hongli Ma, Yun Yan, Weixia Li, Jing Zha. Microglial Nrf2/HO-1 signaling gates remifentanil-induced hyperalgesia via suppressing TRPV4-mediated M1 polarization. Free radical biology & medicine. 2024-02-13. PMID:38295888. |
we used both in vivo and in vitro models to investigate the activation state of spinal cord microglia, the expression of trpv4 channels, and the modulation of the nrf2/ho-1 pathway under remifentanil exposure. |
2024-02-13 |
2024-02-15 |
Not clear |
| Xiaowen Liu, Huamei Cai, Liang Peng, Hongli Ma, Yun Yan, Weixia Li, Jing Zha. Microglial Nrf2/HO-1 signaling gates remifentanil-induced hyperalgesia via suppressing TRPV4-mediated M1 polarization. Free radical biology & medicine. 2024-02-13. PMID:38295888. |
our results revealed a prominent role of spinal cord microglia in rih, demonstrating an apparent microglial m1 polarization and increased trpv4 channel expression. |
2024-02-13 |
2024-02-15 |
Not clear |
| Xiaowen Liu, Huamei Cai, Liang Peng, Hongli Ma, Yun Yan, Weixia Li, Jing Zha. Microglial Nrf2/HO-1 signaling gates remifentanil-induced hyperalgesia via suppressing TRPV4-mediated M1 polarization. Free radical biology & medicine. 2024-02-13. PMID:38295888. |
our research highlights the critical role of spinal cord microglia in rih mediated by the nrf2-trpv4 axis. |
2024-02-13 |
2024-02-15 |
Not clear |
| Longyu Zhang, Jiao Xu, Shi Yin, Qiang Wang, Zhiwei Jia, Tianlin We. Albiflorin Attenuates Neuroinflammation and Improves Functional Recovery After Spinal Cord Injury Through Regulating LSD1-Mediated Microglial Activation and Ferroptosis. Inflammation. 2024-02-10. PMID:38340239. |
meanwhile, af attenuated neuron apoptosis and microglia activation, reduced the production of pro-inflammatory cytokines and iron accumulation, and inhibited spinal cord ferroptosis following sci in rats. |
2024-02-10 |
2024-02-14 |
rat |
| Jie Ju, Zheng Li, Xiaoqian Jia, Xiaoling Peng, Jihong Wang, Feng Ga. Interleukin-18 in chronic pain: Focus on pathogenic mechanisms and potential therapeutic targets. Pharmacological research. vol 201. 2024-02-03. PMID:38295914. |
and il-18 is located in microglia, while il-18r is mostly located in astrocytes in the spinal cord. |
2024-02-03 |
2024-02-06 |
Not clear |
| Yeqi Li, Cui Yin, Jinhong Jiang, Huan Yang, Feifei Zhang, Yanhong Xing, Wuyang Wang, Chen L. Tumor necrosis factor α-induced protein 8-like-2 controls microglia phenotype via metabolic reprogramming in BV2 microglial cells and responses to neuropathic pain. The international journal of biochemistry & cell biology. 2024-02-03. PMID:38309648. |
tnfaip8l2 suppresses inflammatory microglial activation and promotes restorative microglial activation in bv2 microglial cells and in spinal cord microglia after neuropathic pain. |
2024-02-03 |
2024-02-06 |
Not clear |
| Alberto Granzotto, Amanda McQuade, Jean Paul Chadarevian, Hayk Davtyan, Stefano L Sensi, Ian Parker, Mathew Blurton-Jones, Ian Smit. ER and SOCE Ca bioRxiv : the preprint server for biology. 2024-01-31. PMID:38293075. |
er and soce ca the central nervous system (cns) is constantly surveilled by microglia, highly motile and dynamic cells deputed to act as the first line of immune defense in the brain and spinal cord. |
2024-01-31 |
2024-02-02 |
Not clear |
| Amanda Wolf-Johnston, Youko Ikeda, Irina V Zabbarova, Anthony J Kanai, Sheldon Bastacky, Robert Moldwin, Joel Nh Stern, Edwin K Jackson, Lori A Birde. Purine nucleoside phosphorylase inhibition- an effective approach for the treatment of chemical hemorrhagic cystitis. JCI insight. 2024-01-25. PMID:38271096. |
cyp-treated rats exhibited multiple abnormalities including increased urinary frequency and neural mechanosensitivity, reduced bladder levels of inosine, urothelial inflammation/damage, and activation of spinal cord microglia, associated with pain hypersensitivity. |
2024-01-25 |
2024-01-28 |
rat |
| Lauren J Donovan, Caldwell M Bridges, Amy R Nippert, Meng Wang, Shaogen Wu, Thomas E Forman, Elena S Haight, Nolan A Huck, Sabrina F Bond, Claire E Jordan, Aysha M Gardner, Ramesh V Nair, Vivianne L Tawfi. Repopulated spinal cord microglia exhibit a unique transcriptome and contribute to pain resolution. Cell reports. vol 43. issue 2. 2024-01-23. PMID:38261512. |
repopulated spinal cord microglia exhibit a unique transcriptome and contribute to pain resolution. |
2024-01-23 |
2024-01-26 |
mouse |
| Lauren J Donovan, Caldwell M Bridges, Amy R Nippert, Meng Wang, Shaogen Wu, Thomas E Forman, Elena S Haight, Nolan A Huck, Sabrina F Bond, Claire E Jordan, Aysha M Gardner, Ramesh V Nair, Vivianne L Tawfi. Repopulated spinal cord microglia exhibit a unique transcriptome and contribute to pain resolution. Cell reports. vol 43. issue 2. 2024-01-23. PMID:38261512. |
we find that repopulated mouse spinal cord microglia are morphologically distinct from control microglia and exhibit a unique transcriptome. |
2024-01-23 |
2024-01-26 |
mouse |
| Changran Niu, Xinpei Yue, Juan Ji An, Robert Bass, Haifei Xu, Baoji X. Genetic Dissection of BDNF and TrkB Expression in Glial Cells. Biomolecules. vol 14. issue 1. 2024-01-23. PMID:38254691. |
surprisingly, we found no bdnf- or trkb-expressing microglia in examined cns regions, including the somatomotor cortex, hippocampal ca1, and spinal cord. |
2024-01-23 |
2024-01-25 |
mouse |
| Yuyi Luo, Zhengbo Wan. The Impact of Microglia on Neurodevelopment and Brain Function in Autism. Biomedicines. vol 12. issue 1. 2024-01-23. PMID:38255315. |
microglia, as one of the main types of glial cells in the central nervous system (cns), are widely distributed throughout the brain and spinal cord. |
2024-01-23 |
2024-01-25 |
Not clear |
| Fengchun Wu, Yu Lin, Lili Xiao, Qiyong Chen, Fengfei Lin, Renbin L. Administration with curcumin alleviates spinal cord ischemia-reperfusion injury by regulating anti-oxidative stress and microglia activation-mediated neuroinflammation via Nrf2/NF-κB axis. In vitro cellular & developmental biology. Animal. 2024-01-16. PMID:38228998. |
administration with curcumin alleviates spinal cord ischemia-reperfusion injury by regulating anti-oxidative stress and microglia activation-mediated neuroinflammation via nrf2/nf-κb axis. |
2024-01-16 |
2024-01-19 |
rat |