| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rajesh Narendran, Savannah Tollefson, Michael L Himes, Jennifer Paris, Brian Lopresti, Roberto Ciccocioppo, N Scott Maso. Nociceptin Receptors Upregulated in Cocaine Use Disorder: A Positron Emission Tomography Imaging Study Using [ The American journal of psychiatry. vol 176. issue 6. 2019-12-30. PMID:31055968. |
it also inhibits the release of a wide array of neurotransmitters, including dopamine and glutamate, which allows for it to block the rewarding properties of cocaine. |
2019-12-30 |
2023-08-13 |
Not clear |
| B M Siemsen, C M Reichel, K C Leong, C Garcia-Keller, C D Gipson, S Spencer, J A McFaddin, K N Hooker, P W Kalivas, M D Scofiel. Effects of Methamphetamine Self-Administration and Extinction on Astrocyte Structure and Function in the Nucleus Accumbens Core. Neuroscience. vol 406. 2019-12-24. PMID:30926546. |
following 2-h cocaine or methamphetamine self-administration (sa) and extinction, rodents display decreased levels of basal glutamate in the nucleus accumbens core (nacore), which transitions to elevated glutamate levels during drug seeking. |
2019-12-24 |
2023-08-13 |
Not clear |
| B M Siemsen, C M Reichel, K C Leong, C Garcia-Keller, C D Gipson, S Spencer, J A McFaddin, K N Hooker, P W Kalivas, M D Scofiel. Effects of Methamphetamine Self-Administration and Extinction on Astrocyte Structure and Function in the Nucleus Accumbens Core. Neuroscience. vol 406. 2019-12-24. PMID:30926546. |
we hypothesized that, like cocaine, this glutamate 'overflow' during methamphetamine seeking arises via decreased expression of the astroglial glutamate transporter glt-1, and withdrawal of perisynaptic astroglial processes (paps) from synapses. |
2019-12-24 |
2023-08-13 |
Not clear |
| Gopakumar P. Panikka. Cocaine Addiction: Neurobiology and Related Current Research in Pharmacotherapy. Substance abuse. vol 20. issue 3. 2019-11-20. PMID:12511828. |
the vicissitudes in the dopamine theory of brain reward mechanisms, dopaminergic effects of cocaine, and emerging roles of gaba, serotonin, glutamate, and nitric oxide in cocaine addiction and its sequelae are discussed. |
2019-11-20 |
2023-08-12 |
Not clear |
| Luyi Zhou, Haley Andersen, Adrian C Arreola, Jill R Turner, Pavel I Ortinsk. Behavioral History of Withdrawal Influences Regulation of Cocaine Seeking by Glutamate Re-Uptake. PloS one. vol 11. issue 9. 2019-11-20. PMID:27685834. |
behavioral history of withdrawal influences regulation of cocaine seeking by glutamate re-uptake. |
2019-11-20 |
2023-08-13 |
rat |
| Luyi Zhou, Haley Andersen, Adrian C Arreola, Jill R Turner, Pavel I Ortinsk. Behavioral History of Withdrawal Influences Regulation of Cocaine Seeking by Glutamate Re-Uptake. PloS one. vol 11. issue 9. 2019-11-20. PMID:27685834. |
withdrawal from cocaine regulates expression of distinct glutamate re-uptake transporters in the nucleus accumbens (nac). |
2019-11-20 |
2023-08-13 |
rat |
| Luyi Zhou, Haley Andersen, Adrian C Arreola, Jill R Turner, Pavel I Ortinsk. Behavioral History of Withdrawal Influences Regulation of Cocaine Seeking by Glutamate Re-Uptake. PloS one. vol 11. issue 9. 2019-11-20. PMID:27685834. |
in this study, we examined the cumulative effect of glutamate re-uptake by multiple excitatory amino acid transporters (eaats) on drug-seeking at two different stages of withdrawal from self-administered cocaine. |
2019-11-20 |
2023-08-13 |
rat |
| Luyi Zhou, Haley Andersen, Adrian C Arreola, Jill R Turner, Pavel I Ortinsk. Behavioral History of Withdrawal Influences Regulation of Cocaine Seeking by Glutamate Re-Uptake. PloS one. vol 11. issue 9. 2019-11-20. PMID:27685834. |
these results indicate that behavioral history of withdrawal influences the effect of re-uptake mediated glutamate clearance on cocaine seeking. |
2019-11-20 |
2023-08-13 |
rat |
| Jeffery D Steketee, Kun Li. Effects of repeated cocaine administration on dopamine D1 receptor modulation of mesocorticolimbic GABA and glutamate transmission. Brain research. vol 1698. 2019-11-04. PMID:30075100. |
effects of repeated cocaine administration on dopamine d1 receptor modulation of mesocorticolimbic gaba and glutamate transmission. |
2019-11-04 |
2023-08-13 |
Not clear |
| Jeffery D Steketee, Kun Li. Effects of repeated cocaine administration on dopamine D1 receptor modulation of mesocorticolimbic GABA and glutamate transmission. Brain research. vol 1698. 2019-11-04. PMID:30075100. |
the present report tested the hypothesis that daily injections of cocaine would enhance d1 receptor responsiveness by infusing the d1 receptor agonist skf 38393 into the mpfc and monitoring glutamate and/or gaba release in the mpfc, nucleus accumbens and vta of saline- and cocaine-pretreated animals using in vivo microdialysis. |
2019-11-04 |
2023-08-13 |
Not clear |
| Jeffery D Steketee, Kun Li. Effects of repeated cocaine administration on dopamine D1 receptor modulation of mesocorticolimbic GABA and glutamate transmission. Brain research. vol 1698. 2019-11-04. PMID:30075100. |
intra-mpfc skf 38393 had no effect on glutamate levels in animals 1 day after daily cocaine treatments, increased mpfc glutamate at 7 days of withdrawal and reverted to decreasing glutamate at 30 days of withdrawal. |
2019-11-04 |
2023-08-13 |
Not clear |
| Jeffery D Steketee, Kun Li. Effects of repeated cocaine administration on dopamine D1 receptor modulation of mesocorticolimbic GABA and glutamate transmission. Brain research. vol 1698. 2019-11-04. PMID:30075100. |
infusion of skf 38393 into the mpfc of animals previously exposed to cocaine increased and reduced glutamate release in the nucleus accumbens after 7 and 30 days of withdrawal, respectively and increased glutamate levels in the vta 7 and 30 days after daily cocaine injections. |
2019-11-04 |
2023-08-13 |
Not clear |
| Maria A De Luca, Matthew W Buczynski, Gaetano Di Chiar. Loren Parsons' contribution to addiction neurobiology. Addiction biology. vol 23. issue 6. 2019-10-07. PMID:29949237. |
larry also applied microdialysis to study gaba and glutamate's role in ethanol dependence and heroin reinforcement, providing in vivo evidence for a sensitization of corticotropin-releasing factor-dependent release of gaba in the central amygdala in withdrawal from chronic ethanol and for a reduction of gaba transmission in the ventral pallidum in heroin but not cocaine intravenous self-administration. |
2019-10-07 |
2023-08-13 |
Not clear |
| Xia Li, Xiao-Qing Peng, Chloe J Jordan, Jie Li, Guo-Hua Bi, Yi He, Hong-Ju Yang, Hai-Ying Zhang, Eliot L Gardner, Zheng-Xiong X. mGluR5 antagonism inhibits cocaine reinforcement and relapse by elevation of extracellular glutamate in the nucleus accumbens via a CB1 receptor mechanism. Scientific reports. vol 8. issue 1. 2019-09-23. PMID:29487381. |
mglur5 antagonism inhibits cocaine reinforcement and relapse by elevation of extracellular glutamate in the nucleus accumbens via a cb1 receptor mechanism. |
2019-09-23 |
2023-08-13 |
Not clear |
| Xia Li, Xiao-Qing Peng, Chloe J Jordan, Jie Li, Guo-Hua Bi, Yi He, Hong-Ju Yang, Hai-Ying Zhang, Eliot L Gardner, Zheng-Xiong X. mGluR5 antagonism inhibits cocaine reinforcement and relapse by elevation of extracellular glutamate in the nucleus accumbens via a CB1 receptor mechanism. Scientific reports. vol 8. issue 1. 2019-09-23. PMID:29487381. |
metabotropic glutamate receptor 5 (mglur5) antagonism inhibits cocaine self-administration and reinstatement of drug-seeking behavior. |
2019-09-23 |
2023-08-13 |
Not clear |
| Allison R Bechard, Peter U Hamor, Lizhen Wu, Marek Schwendt, Lori A Knacksted. The effects of clavulanic acid and amoxicillin on cue-primed reinstatement of cocaine seeking. Behavioral neuroscience. vol 133. issue 2. 2019-07-22. PMID:30714803. |
research using the cocaine self-administration and reinstatement animal model of relapse finds that the beta-lactam antibiotic, ceftriaxone, attenuates cocaine-primed reinstatement of cocaine seeking and upregulates two proteins that regulate glutamate release and reuptake (xct and glt-1, respectively) in the nucleus accumbens core (nac). |
2019-07-22 |
2023-08-13 |
rat |
| B M Siemsen, G Giannotti, J A McFaddin, M D Scofield, Jacqueline F McGint. Biphasic effect of abstinence duration following cocaine self-administration on spine morphology and plasticity-related proteins in prelimbic cortical neurons projecting to the nucleus accumbens core. Brain structure & function. vol 224. issue 2. 2019-07-01. PMID:30498893. |
cocaine self-administration (sa) in rats dysregulates glutamatergic signaling in the prelimbic (prl) cortex and glutamate release in the nucleus accumbens (na) core, promoting cocaine seeking. |
2019-07-01 |
2023-08-13 |
rat |
| M P García-Pardo, C Calpe-López, J Miñarro, M A Aguila. Role of N-methyl-D-aspartate receptors in the long-term effects of repeated social defeat stress on the rewarding and psychomotor properties of cocaine in mice. Behavioural brain research. vol 361. 2019-06-04. PMID:30557580. |
the aim of this work is to determine the role of n-methyl-d-aspartate (nmda) glutamate receptors in the influence of social stress on the conditioned place preference and locomotor sensitization induced by cocaine. |
2019-06-04 |
2023-08-13 |
mouse |
| M P García-Pardo, C Calpe-López, J Miñarro, M A Aguila. Role of N-methyl-D-aspartate receptors in the long-term effects of repeated social defeat stress on the rewarding and psychomotor properties of cocaine in mice. Behavioural brain research. vol 361. 2019-06-04. PMID:30557580. |
our results show that glutamate nmda receptors are involved in the higher vulnerability to cocaine effects provoked by exposure to social defeat. |
2019-06-04 |
2023-08-13 |
mouse |
| Gerard M J Beaudoin, Jorge A Gomez, Jessica Perkins, Julie L Bland, Alyssa K Petko, Carlos A Paladin. Cocaine Selectively Reorganizes Excitatory Inputs to Substantia Nigra Pars Compacta Dopamine Neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 38. issue 5. 2019-05-29. PMID:29263240. |
this contrasts with ventral tegmental area (vta) dopamine neurons, whose glutamate afferents react robustly to cocaine. |
2019-05-29 |
2023-08-13 |
mouse |