| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Na Zhao, Wenhui Qiao, Fuyao Li, Yingxue Ren, Jiaying Zheng, Yuka A Martens, Xusheng Wang, Ling Li, Chia-Chen Liu, Kai Chen, Yiyang Zhu, Tadafumi C Ikezu, Zonghua Li, Axel D Meneses, Yunjung Jin, Joshua A Knight, Yixing Chen, Ligia Bastea, Cynthia Linares, Berkiye Sonustun, Lucy Job, Madeleine L Smith, Manling Xie, Yong U Liu, Anthony D Umpierre, Koichiro Haruwaka, Zachary S Quicksall, Peter Storz, Yan W Asmann, Long-Jun Wu, Guojun B. Elevating microglia TREM2 reduces amyloid seeding and suppresses disease-associated microglia. The Journal of experimental medicine. vol 219. issue 12. 2022-09-15. PMID:36107206. |
trem2 is exclusively expressed by microglia in the brain and is strongly linked to the risk for alzheimer's disease (ad). |
2022-09-15 |
2023-08-14 |
mouse |
| Ling-Xiao Cao, Wen-Zheng Hu, Wei Dong, Qing Yang, Jin-Hui Yin, Yue Wang, Xin Ni, Yue Huan. Neuropathological report of propionic acidemia. Neuropathology : official journal of the Japanese Society of Neuropathology. 2022-09-14. PMID:36102083. |
spongiosis, vacuolization, and the appearance of alzheimer type ii astrocytes and activated microglia were observed as well. |
2022-09-14 |
2023-08-14 |
human |
| Jian Jing Siew, Yijuang Chern, Kay-Hooi Khoo, Takashi Angat. Roles of Siglecs in neurodegenerative diseases. Molecular aspects of medicine. 2022-09-11. PMID:36089405. |
recent studies have revealed the involvement of microglia in neurodegenerative diseases, such as alzheimer's disease, through the modulation of neuroinflammation. |
2022-09-11 |
2023-08-14 |
Not clear |
| Bijay Parajuli, Schuichi Koizum. Strategies for Manipulating Microglia to Determine Their Role in the Healthy and Diseased Brain. Neurochemical research. 2022-09-10. PMID:36085395. |
in this article, we review the role of microglia in the normal brain and in various pathological brain conditions, such as alzheimer's disease and multiple sclerosis. |
2022-09-10 |
2023-08-14 |
Not clear |
| Qixue Wang, Mengna Lu, Xinyu Zhu, Xinyi Gu, Ting Zhang, Chenyi Xia, Li Yang, Ying Xu, Mingmei Zho. The role of microglia immunometabolism in neurodegeneration: Focus on molecular determinants and metabolic intermediates of metabolic reprogramming. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 153. 2022-09-09. PMID:36076537. |
this paper provides an overview of the metabolic reprogramming of microglia, the major pathways involved in recent advances in five major neurodegenerative diseases of aging (ndas), including alzheimer's disease (ad), parkinson's disease (pd), multiple sclerosis (ms), amyotrophic lateral sclerosis (als), and frontotemporal dementia (ftd), etc. |
2022-09-09 |
2023-08-14 |
Not clear |
| Giulia Di Benedetto, Chiara Burgaletto, Carlo Maria Bellanca, Antonio Munafò, Renato Bernardini, Giuseppina Cantarell. Role of Microglia and Astrocytes in Alzheimer's Disease: From Neuroinflammation to Ca Cells. vol 11. issue 17. 2022-09-09. PMID:36078138. |
role of microglia and astrocytes in alzheimer's disease: from neuroinflammation to ca alzheimer's disease (ad) is the most common form of dementia worldwide, with a complex, poorly understood pathogenesis. |
2022-09-09 |
2023-08-14 |
Not clear |
| Haoshen Shi, Zhuoran Yin, Yosef Koronyo, Dieu-Trang Fuchs, Julia Sheyn, Miyah R Davis, Jered W Wilson, Milica A Margeta, Kristen M Pitts, Shawn Herron, Seiko Ikezu, Tsuneya Ikezu, Stuart L Graham, Vivek K Gupta, Keith L Black, Mehdi Mirzaei, Oleg Butovsky, Maya Koronyo-Hamaou. Regulating microglial miR-155 transcriptional phenotype alleviates Alzheimer's-induced retinal vasculopathy by limiting Clec7a/Galectin-3 Acta neuropathologica communications. vol 10. issue 1. 2022-09-08. PMID:36076283. |
despite growing interest in studying manifestations of alzheimer's disease (ad) in the retina, a cns organ accessible to noninvasive high-resolution imaging, to date mgnd microglia have not been studied in the ad retina. |
2022-09-08 |
2023-08-14 |
Not clear |
| Wei Dai, Ru-Meng Yao, Tian-Yue Mi, Li-Ming Zhang, Hong-Liang Wu, Jin-Bo Cheng, Yun-Feng L. Cognition-enhancing effect of YL-IPA08, a potent ligand for the translocator protein (18 kDa) in the 5 × FAD transgenic mouse model of Alzheimer's pathology. Journal of psychopharmacology (Oxford, England). 2022-09-07. PMID:36069168. |
the change of tspo and the dysfunction of microglia are closely related to the pathogenesis of alzheimer's disease (ad). |
2022-09-07 |
2023-08-14 |
mouse |
| Peng Zhao, Yuanzhong Xu, LuLin Jiang, Xuejun Fan, Leike Li, Xin Li, Hisashi Arase, Yingjun Zhao, Wei Cao, Hui Zheng, Huaxi Xu, Qingchun Tong, Ningyan Zhang, Zhiqiang A. A tetravalent TREM2 agonistic antibody reduced amyloid pathology in a mouse model of Alzheimer's disease. Science translational medicine. vol 14. issue 661. 2022-09-07. PMID:36070367. |
triggering receptor expressed on myeloid cells 2 (trem2) plays crucial roles in alzheimer's disease (ad) by regulating microglia migration toward, and phagocytosis of oligomeric amyloid-β (oaβ) and amyloid plaques. |
2022-09-07 |
2023-08-14 |
mouse |
| Chao Gao, Xin Shen, Yuyan Tan, Shengdi Che. Pathogenesis, therapeutic strategies and biomarker development based on "omics" analysis related to microglia in Alzheimer's disease. Journal of neuroinflammation. vol 19. issue 1. 2022-09-04. PMID:36058959. |
pathogenesis, therapeutic strategies and biomarker development based on "omics" analysis related to microglia in alzheimer's disease. |
2022-09-04 |
2023-08-14 |
Not clear |
| Boris-Stephan Rauchmann, Matthias Brendel, Nicolai Franzmeier, Lena Trappmann, Mirlind Zaganjori, Ersin Ersoezlue, Estrella Morenas-Rodriguez, Selim Guersel, Lena Burow, Carolin Kurz, Jan Haeckert, Maia Tatò, Julia Utecht, Boris Papazov, Oliver Pogarell, Daniel Janowitz, Katharina Buerger, Michael Ewers, Carla Palleis, Endy Weidinger, Gloria Biechele, Sebastian Schuster, Anika Finze, Florian Eckenweber, Rainer Rupprecht, Axel Rominger, Oliver Goldhardt, Timo Grimmer, Daniel Keeser, Sophia Stoecklein, Olaf Dietrich, Peter Bartenstein, Johannes Levin, Günter Höglinger, Robert Perneczk. Microglial Activation and Connectivity in Alzheimer Disease and Aging. Annals of neurology. 2022-09-02. PMID:36053756. |
alzheimer disease (ad) is characterized by amyloid β (aβ) plaques and neurofibrillary tau tangles, but increasing evidence suggests that neuroinflammation also plays a key role, driven by the activation of microglia. |
2022-09-02 |
2023-08-14 |
Not clear |
| Mauro Montalbano, Lajja Majmundar, Urmi Sengupta, Leiana Fung, Rakez Kaye. Pathological tau signatures and nuclear alterations in neurons, astrocytes and microglia in Alzheimer's disease, progressive supranuclear palsy, and dementia with Lewy bodies. Brain pathology (Zurich, Switzerland). 2022-09-02. PMID:36054524. |
pathological tau signatures and nuclear alterations in neurons, astrocytes and microglia in alzheimer's disease, progressive supranuclear palsy, and dementia with lewy bodies. |
2022-09-02 |
2023-08-14 |
mouse |
| Maricarmen Hernández-Rodríguez, Cecilia Flores Clemente, Martha Edith Macías-Pérez, Rolando Alberto Rodríguez-Fonseca, M Inés Nicolás Vázquez, Joel Martínez, Rene Miranda Ruvalcaba, Martín Martínez Rosas, Elvia Mera Jiméne. Contribution of hyperglycemia-induced changes in microglia to Alzheimer's disease pathology. Pharmacological reports : PR. 2022-08-30. PMID:36042131. |
contribution of hyperglycemia-induced changes in microglia to alzheimer's disease pathology. |
2022-08-30 |
2023-08-14 |
Not clear |
| Qing Wang, Chunming Xi. Microglia activation linking amyloid-β drive tau spatial propagation in Alzheimer's disease. Frontiers in neuroscience. vol 16. 2022-08-29. PMID:36033617. |
microglia activation linking amyloid-β drive tau spatial propagation in alzheimer's disease. |
2022-08-29 |
2023-08-14 |
Not clear |
| Yuqian An, Yi Li, Yujun Hou, Shichao Huang, Gang Pe. Alzheimer's Amyloid- Oxidative medicine and cellular longevity. vol 2022. 2022-08-29. PMID:36035216. |
alzheimer's amyloid- microglia play important roles in maintenance of brain homeostasis, while due to some pathological stimuli in aging-related neurodegenerative diseases including alzheimer's disease, they are malfunctioning. |
2022-08-29 |
2023-08-14 |
Not clear |
| Marie-Kim St-Pierre, Jared VanderZwaag, Sophia Loewen, Marie-Ève Trembla. All roads lead to heterogeneity: The complex involvement of astrocytes and microglia in the pathogenesis of Alzheimer's disease. Frontiers in cellular neuroscience. vol 16. 2022-08-29. PMID:36035256. |
all roads lead to heterogeneity: the complex involvement of astrocytes and microglia in the pathogenesis of alzheimer's disease. |
2022-08-29 |
2023-08-14 |
Not clear |
| Stefan Wendt, Sora Johnson, Nicholas L Weilinger, Christopher Groten, Stefano Sorrentino, Jonathan Frew, Lucy Yang, Hyun B Choi, Haakon B Nygaard, Brian A MacVica. Simultaneous imaging of redox states in dystrophic neurites and microglia at Aβ plaques indicate lysosome accumulation not microglia correlate with increased oxidative stress. Redox biology. vol 56. 2022-08-29. PMID:36037587. |
the inter-relationship between microglia dynamics and oxidative stress (ox-stress) in dystrophic neurites (dns) at alzheimer's disease (ad) plaques may contribute to the pathological changes in neurons. |
2022-08-29 |
2023-08-14 |
mouse |
| Sumonto Mitra, Ruchi Gera, Julia Sundheimer, Marine Lemee, Lars U Wahlberg, Bengt Linderoth, Maria Eriksdotter, Homira Behbahan. Microglia Impairs Proliferation and Induces Senescence In-Vitro in NGF Releasing Cells Used in Encapsulated Cell Biodelivery for Alzheimer's Disease Therapy. International journal of molecular sciences. vol 23. issue 16. 2022-08-26. PMID:36012296. |
microglia impairs proliferation and induces senescence in-vitro in ngf releasing cells used in encapsulated cell biodelivery for alzheimer's disease therapy. |
2022-08-26 |
2023-08-14 |
human |
| Yanqing Chen, Zhen Liu, Ping Gong, Haibo Zhang, Yijun Chen, Songquan Yao, Wei Li, Yan Zhang, Yang Y. The Chemerin/CMKLR1 Axis Is Involved in the Recruitment of Microglia to Aβ Deposition through p38 MAPK Pathway. International journal of molecular sciences. vol 23. issue 16. 2022-08-26. PMID:36012305. |
the accumulation of microglia around senile plaques is one of the pathological features of alzheimer's disease (ad). |
2022-08-26 |
2023-08-14 |
mouse |
| Jozef Nahalk. 1-L Transcription in Alzheimer's Disease. Current issues in molecular biology. vol 44. issue 8. 2022-08-25. PMID:36005139. |
alzheimer's disease is a very complex disease and better explanations and models are needed to understand how neurons are affected and microglia are activated. |
2022-08-25 |
2023-08-14 |
Not clear |