| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wenxin Zhang, Mingqian Yu, Qiyue Zhang, Zhuo Yang, Tao Zhan. DFO treatment protects against depression-like behaviors and cognitive impairment in CUMS mice. Brain research bulletin. 2022-07-02. PMID:35779818. |
together, these findings suggest that dfo likely plays a protective role in cognitive impairments and synaptic plasticity deficits resulting from depression. |
2022-07-02 |
2023-08-14 |
mouse |
| Jiahao Zhou, Yao Ma, Jinfeng Chen, Dan Yao, Caixia Feng, Yankai Dong, Yating Ren, Hengyu Ma, Zhifei Wang, Ge Li, Yao Ma, Hui Li, Zhongliang Zh. Effects of RhoA on depression-like behavior in prenatally stressed offspring rats. Behavioural brain research. 2022-06-21. PMID:35728732. |
rhoa (ras homology family member a) plays an important role in stress-induced changes in synaptic plasticity, participating in the development of depression by activating the downstream effector rock (rho-associated protein kinase). |
2022-06-21 |
2023-08-14 |
rat |
| Haixia Wang, Yi He, Zuoli Sun, Siyu Ren, Mingxia Liu, Gang Wang, Jian Yan. Microglia in depression: an overview of microglia in the pathogenesis and treatment of depression. Journal of neuroinflammation. vol 19. issue 1. 2022-06-06. PMID:35668399. |
microglia regulate inflammation, synaptic plasticity, and the formation of neural networks, all of which affect depression. |
2022-06-06 |
2023-08-14 |
Not clear |
| Guoli Wang, Tianyue An, Cong Lei, Xiaofeng Zhu, Li Yang, Lianxue Zhang, Ronghua Zhan. Antidepressant-like effect of ginsenoside Rb1 on potentiating synaptic plasticity via the miR-134-mediated BDNF signaling pathway in a mouse model of chronic stress-induced depression. Journal of ginseng research. vol 46. issue 3. 2022-05-23. PMID:35600767. |
antidepressant-like effect of ginsenoside rb1 on potentiating synaptic plasticity via the mir-134-mediated bdnf signaling pathway in a mouse model of chronic stress-induced depression. |
2022-05-23 |
2023-08-13 |
mouse |
| Trine Waage Rygvold, Christoffer Hatlestad-Hall, Torbjørn Elvsåshagen, Torgeir Moberget, Stein Andersso. Long-Term Potentiation-Like Visual Synaptic Plasticity Is Negatively Associated With Self-Reported Symptoms of Depression and Stress in Healthy Adults. Frontiers in human neuroscience. vol 16. 2022-05-23. PMID:35601905. |
long-term potentiation-like visual synaptic plasticity is negatively associated with self-reported symptoms of depression and stress in healthy adults. |
2022-05-23 |
2023-08-13 |
Not clear |
| Ya-Nan Gao, Yong-Qian Zhang, Hao Wang, Yu-Lin Deng, Nuo-Min L. A New Player in Depression: MiRNAs as Modulators of Altered Synaptic Plasticity. International journal of molecular sciences. vol 23. issue 9. 2022-05-14. PMID:35562946. |
a new player in depression: mirnas as modulators of altered synaptic plasticity. |
2022-05-14 |
2023-08-13 |
Not clear |
| Xin Liang, Jing Tang, Ying-Qiang Qi, Yan-Min Luo, Chun-Mao Yang, Xiao-Yun Dou, Lin Jiang, Qian Xiao, Lei Zhang, Feng-Lei Chao, Chun-Ni Zhou, Yong Tan. Exercise more efficiently regulates the maturation of newborn neurons and synaptic plasticity than fluoxetine in a CUS-induced depression mouse model. Experimental neurology. 2022-05-07. PMID:35525307. |
exercise more efficiently regulates the maturation of newborn neurons and synaptic plasticity than fluoxetine in a cus-induced depression mouse model. |
2022-05-07 |
2023-08-13 |
mouse |
| Haider Sarwar, Shafiya Imtiaz Rafiqi, Showkat Ahmad, Sruthi Jinna, Sawleha Arshi Khan, Tamanna Karim, Omar Qureshi, Zeeshan A Zahid, Jon D Elhai, Jason C Levine, Shazia J Naqvi, Juan C Jaume, Shahnawaz Ima. Hyperinsulinemia Associated Depression. Clinical medicine insights. Endocrinology and diabetes. vol 15. 2022-05-02. PMID:35494421. |
increased inflammatory cytokines have also been shown to disrupt neurotransmitter metabolism and synaptic plasticity which play a role in the development of depression via inhibiting serotonin, dopamine, melatonin, and glutamate signaling. |
2022-05-02 |
2023-08-13 |
Not clear |
| Linhong Jiang, Haoluo Zhang, Yuman He, Haxiaoyu Liu, Shu Li, Rong Chen, Shuang Han, Yuanyi Zhou, Jiamei Zhang, Xuemei Wan, Rui Xu, Shaomin Wang, Hui Gu, Qingfan Wei, Feng Qin, Yue Zhao, Yaxing Chen, Hongchun Li, Liang Wang, Xiaojie Wang, Yonghai Wang, Yanping Dai, Min Li, Yuanyuan Chen, Huaqin Zhang, Yiming Hu, Qian Bu, Yinglan Zhao, Xiaobo Ce. Synapse differentiation-induced gene 1 regulates stress-induced depression through interaction with the AMPA receptor GluA2 subunit of nucleus accumbens in male mice. Neuropharmacology. 2022-05-02. PMID:35500677. |
alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors (ampars) are key regulators during the process of synaptic plasticity in major depression disorder (mdd). |
2022-05-02 |
2023-08-13 |
mouse |
| Feng Gao, Shaojie Yang, Juan Wang, Guoqi Zh. cAMP-PKA cascade: An outdated topic for depression? Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 150. 2022-04-29. PMID:35486973. |
the cyclic amp (camp)/protein kinase a (pka) cascade, a major cross-species cellular signaling pathway, is supposed as important player and regulator of depression onset by controlling synaptic plasticity, cytokinesis, transcriptional regulation and hpa axis. |
2022-04-29 |
2023-08-13 |
Not clear |
| Qingbo Lu, Fangfang Wu, Jiao Jiao, Le Xue, Ruize Song, Yachen Shi, Yan Kong, Jianfei Sun, Ning Gu, Ming-Hu Han, Zhijun Zhan. Selective activation of ABCA1/ApoA1 signaling in the V1 by magnetoelectric stimulation ameliorates depression via regulation of synaptic plasticity. iScience. vol 25. issue 5. 2022-04-28. PMID:35479414. |
selective activation of abca1/apoa1 signaling in the v1 by magnetoelectric stimulation ameliorates depression via regulation of synaptic plasticity. |
2022-04-28 |
2023-08-13 |
mouse |
| Shayan Rahmani, Sepideh Kadkhoda, Soudeh Ghafouri-Far. Synaptic plasticity and depression: the role of miRNAs dysregulation. Molecular biology reports. 2022-04-20. PMID:35441941. |
synaptic plasticity and depression: the role of mirnas dysregulation. |
2022-04-20 |
2023-08-13 |
Not clear |
| b' Carla L S\\xc3\\xa1nchez-Lafuente, Lisa E Kalynchuk, Hector J Caruncho, Juan Ausi\\xc3\\xb. The Role of MeCP2 in Regulating Synaptic Plasticity in the Context of Stress and Depression. Cells. vol 11. issue 4. 2022-02-25. PMID:35203405.' |
the role of mecp2 in regulating synaptic plasticity in the context of stress and depression. |
2022-02-25 |
2023-08-13 |
Not clear |
| Shanyao Zhou, Rui Chen, Yanling She, Xuanjun Liu, Hui Zhao, Cheng Li, Yanbin Ji. A new perspective on depression and neuroinflammation: Non-coding RNA. Journal of psychiatric research. vol 148. 2022-02-22. PMID:35193033. |
neuroinflammation may affect depression by regulating the production of immune factors, immune cell activation, neuron generation, synaptic plasticity, and neurotransmission. |
2022-02-22 |
2023-08-13 |
Not clear |
| John Q Wang, Justin D Derges, Alaya Bodepudi, Nikhila Pokala, Li-Min Ma. Roles of non-receptor tyrosine kinases in pathogenesis and treatment of depression. Journal of integrative neuroscience. vol 21. issue 1. 2022-02-15. PMID:35164461. |
these long-lasting adaptations contribute to the remodeling of signaling network or synaptic plasticity critical for the vulnerability to depression and the therapeutic efficacy of antidepressants. |
2022-02-15 |
2023-08-13 |
Not clear |
| Jing Gao, Ming-Yin Lai, Thi Tanh-Tam Mai, Wen Fu, Meng-Yu Wang, Bai-le Ning, Wen-Bin F. [Effects of electroacupuncture on BNDF/mTORC1 signaling pathway and synaptic plasticity in prefrontal cortex of rats exposed to chronic unpredictable mild stress]. Zhen ci yan jiu = Acupuncture research. vol 47. issue 1. 2022-02-07. PMID:35128865. |
to investigate the effects of electroacupuncture (ea) on the expression of related proteins in the brain-derived neurotrophic factor (bdnf)/mammalian target of rapamycin complex 1 (mtorc1) signaling pathway and synapse-associated proteins and the density of dendrite spines in the prefrontal cortex (pfc) of depression model rats, and to reveal the underlying mechanism by which ea regulates the synaptic plasticity to improve depressive symptoms. |
2022-02-07 |
2023-08-13 |
rat |
| Chao Yang, Huan-Yu Ni, Jia-Jie Yin, Ting Zhou, Qiu-Xiang Gu, Ting-Ting Chen, Cheng-Yun Ca. Atorvastatin ameliorates depressive behaviors via regulation of α7nAChR expression by PI3K/Akt-BDNF pathway in mice. Biochemical and biophysical research communications. vol 593. 2022-01-22. PMID:35063770. |
our study suggests that av plays an antidepressant role by regulating synaptic plasticity of vhpc through pi3k/akt-bdnf signaling pathway, which may be a good choice for depression treatment. |
2022-01-22 |
2023-08-13 |
mouse |
| Zhuoyu Ren, Mingling Wang, Mokhtar Aldhabi, Rui Zhang, Yongxin Liu, Shaoyan Liu, Rundong Tang, Zuolei Che. Low-dose S-ketamine exerts antidepressant-like effects via enhanced hippocampal synaptic plasticity in postpartum depression rats. Neurobiology of stress. vol 16. 2022-01-03. PMID:34977283. |
low-dose s-ketamine exerts antidepressant-like effects via enhanced hippocampal synaptic plasticity in postpartum depression rats. |
2022-01-03 |
2023-08-13 |
rat |
| Zhuoyu Ren, Mingling Wang, Mokhtar Aldhabi, Rui Zhang, Yongxin Liu, Shaoyan Liu, Rundong Tang, Zuolei Che. Low-dose S-ketamine exerts antidepressant-like effects via enhanced hippocampal synaptic plasticity in postpartum depression rats. Neurobiology of stress. vol 16. 2022-01-03. PMID:34977283. |
our study provides insight into the role of low-dose s-ketamine in antidepressant as well as antianxiety and indicates that maintaining synaptic plasticity is a key target for s-ketamine therapy for postpartum depression induced by reproductive hormone withdrawal. |
2022-01-03 |
2023-08-13 |
rat |
| Damiana Scuteri, Maria Tiziana Corasaniti, Paolo Tonin, Pierluigi Nicotera, Giacinto Bagett. New trends in pharmacological control of neuropsychiatric symptoms of dementia. Current opinion in pharmacology. vol 61. 2021-12-09. PMID:34634603. |
abnormal neuronal and synaptic plasticity occurs in alzheimer's disease (ad) and depression. |
2021-12-09 |
2023-08-13 |
Not clear |