| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fan Li, Manhua Li. A hybrid Convolutional and Recurrent Neural Network for Hippocampus Analysis in Alzheimer's Disease. Journal of neuroscience methods. vol 323. 2020-09-11. PMID:31132373. |
hippocampus is one of the first structures affected by neurodegenerative diseases such as alzheimer's disease (ad) and mild cognitive impairment (mci). |
2020-09-11 |
2023-08-13 |
Not clear |
| Steven M Weisberg, Nora S Newcombe, Anjan Chatterje. Everyday taxi drivers: Do better navigators have larger hippocampi? Cortex; a journal devoted to the study of the nervous system and behavior. vol 115. 2020-09-02. PMID:30884282. |
similar observations, sometimes implicating other sections of the hippocampus, have been made for aging populations and for people with neurodegenerative diseases that affect the hippocampus. |
2020-09-02 |
2023-08-13 |
Not clear |
| Amrutha H Chidananda, Anand Kumar Sharma, Radhika Khandelwal, Yogendra Sharm. Secretagogin Binding Prevents α-Synuclein Fibrillation. Biochemistry. vol 58. issue 46. 2020-06-29. PMID:31617346. |
a significantly reduced level of expression of scgn has been reported in the hippocampus of a mouse model of alzheimer's disease (ad) and in parkinson's patients, although the biochemical implications and mechanistic underpinnings of the altered scgn expression in neurodegenerative diseases remain unknown. |
2020-06-29 |
2023-08-13 |
mouse |
| M J Hackett, A Hollings, S Caine, B E Bewer, M Alaverdashvili, R Takechi, J C L Mamo, M W M Jones, M D de Jonge, P G Paterson, I J Pickering, G N Georg. Elemental characterisation of the pyramidal neuron layer within the rat and mouse hippocampus. Metallomics : integrated biometal science. vol 11. issue 1. 2020-04-14. PMID:30398510. |
interestingly, our study reveals a unique fe gradient across neuron populations within the non-degenerating and pathology free rat hippocampus, which curiously mirrors the pattern of region-specific vulnerability of the hippocampus that has previously been established to occur in various neurodegenerative diseases. |
2020-04-14 |
2023-08-13 |
mouse |
| Rebecca Ward, Weiguo Li, Yasir Abdul, LaDonya Jackson, Guangkuo Dong, Sarah Jamil, Jessica Filosa, Susan C Fagan, Adviye Ergu. NLRP3 inflammasome inhibition with MCC950 improves diabetes-mediated cognitive impairment and vasoneuronal remodeling after ischemia. Pharmacological research. vol 142. 2020-02-13. PMID:30818045. |
nlrp3 inflammasome signaling has been implicated in the development of diabetes and neurodegenerative diseases, but little is known about the impact of nlrp3 activation on functional and structural interaction within the nvu of hippocampus, a critical part of the brain that is involved in forming, organizing, and storing memories. |
2020-02-13 |
2023-08-13 |
rat |
| Fumiko Shigiyama, Makoto Hamanoue, Masaaki Kobayashi, Ken Takamats. Cell-permeable p38 MAP kinase protects adult hippocampal neurons from cell death. Neuroscience letters. vol 699. 2019-12-17. PMID:30735722. |
our findings indicate that cell-permeable p38 protein may be useful in preventing the degeneration of higher brain function occurring through hippocampal neuronal cell death, and furthermore, that the maintenance of intracellular p38 levels could be another therapeutic target for neurodegenerative diseases such as alzheimer's disease (ad). |
2019-12-17 |
2023-08-13 |
Not clear |
| Venkatanaidu Karri, David Ramos, Julia Bauzá Martinez, Antonia Odena, Eliandre Oliveira, Susan L Coort, Chris T Evelo, Edwin C M Mariman, Marta Schuhmacher, Vikas Kuma. Differential protein expression of hippocampal cells associated with heavy metals (Pb, As, and MeHg) neurotoxicity: Deepening into the molecular mechanism of neurodegenerative diseases. Journal of proteomics. vol 187. 2019-12-12. PMID:30017948. |
differential protein expression of hippocampal cells associated with heavy metals (pb, as, and mehg) neurotoxicity: deepening into the molecular mechanism of neurodegenerative diseases. |
2019-12-12 |
2023-08-13 |
Not clear |
| Riya Muckom, Sean McFarland, Chun Yang, Brian Perea, Megan Gentes, Abirami Murugappan, Eric Tran, Jonathan S Dordick, Douglas S Clark, David V Schaffe. High-throughput combinatorial screening reveals interactions between signaling molecules that regulate adult neural stem cell fate. Biotechnology and bioengineering. vol 116. issue 1. 2019-12-11. PMID:30102775. |
advancing our knowledge of how neural stem cell (nsc) behavior in the adult hippocampus is regulated has implications for elucidating basic mechanisms of learning and memory as well as for neurodegenerative disease therapy. |
2019-12-11 |
2023-08-13 |
Not clear |
| Marco Spallazzi, Laura Dobisch, Andreas Becke, David Berron, Daniel Stucht, Steffen Oeltze-Jafra, Paolo Caffarra, Oliver Speck, Emrah Düze. Hippocampal vascularization patterns: A high-resolution 7 Tesla time-of-flight magnetic resonance angiography study. NeuroImage. Clinical. vol 21. 2019-12-11. PMID:30581106. |
the approach presented here for determining hippocampal vascularization patterns in vivo may provide new insights into not only the vulnerability of the hippocampus to vascular and neurodegenerative diseases but also hippocampal vascular plasticity after exercise training. |
2019-12-11 |
2023-08-13 |
human |
| Tomas Ondrejcak, Igor Klyubin, Grant T Corbett, Graham Fraser, Wei Hong, Alexandra J Mably, Matthew Gardener, Jayne Hammersley, Michael S Perkinton, Andrew Billinton, Dominic M Walsh, Michael J Rowa. Cellular Prion Protein Mediates the Disruption of Hippocampal Synaptic Plasticity by Soluble Tau The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 38. issue 50. 2019-10-09. PMID:30355631. |
cellular prion protein mediates the disruption of hippocampal synaptic plasticity by soluble tau intracellular neurofibrillary tangles (nfts) composed of tau protein are a neuropathological hallmark of several neurodegenerative diseases, the most common of which is alzheimer's disease (ad). |
2019-10-09 |
2023-08-13 |
rat |
| Catarina Praça, Akhilesh Rai, Tiago Santos, Ana C Cristovão, Sonia L Pinho, Romeo Cecchelli, Marie-Pierre Dehouck, Liliana Bernardino, Lino S Ferreir. A nanoformulation for the preferential accumulation in adult neurogenic niches. Journal of controlled release : official journal of the Controlled Release Society. vol 284. 2019-10-07. PMID:29902485. |
stimulation of adult neurogenesis by targeting the endogenous neural stem cells (nscs), located in hippocampus and subventricular zone (svz), with nanoformulations has been proposed for brain repair in cases of neurodegenerative diseases. |
2019-10-07 |
2023-08-13 |
mouse |
| Cara M Hueston, James D O'Leary, Alan E Hoban, Danka A Kozareva, Lauren C Pawley, Olivia F O'Leary, John F Cryan, Yvonne M Nola. Chronic interleukin-1β in the dorsal hippocampus impairs behavioural pattern separation. Brain, behavior, and immunity. vol 74. 2019-09-10. PMID:30217534. |
the hippocampus is particularly vulnerable to increases in the pro-inflammatory cytokine interleukin-1β (il-1β), a mediator of neuroinflammation, with elevated levels implicated in the aetiology of neurodegenerative diseases such as alzheimer's and parkinson's, and in stress-related disorders such as depression. |
2019-09-10 |
2023-08-13 |
rat |
| Céline Laurencé, Narimane Zeghbib, Michael Rivard, Sonia Lehri-Boufala, Isabelle Lachaise, Caroline Barau, Philippe Le Corvoisier, Thierry Martens, Laure Garrigue-Antar, Christophe Mori. A new human pyridinium metabolite of furosemide, inhibitor of mitochondrial complex I, is a candidate inducer of neurodegeneration. Biochemical pharmacology. vol 160. 2019-09-09. PMID:30537467. |
moreover, in mice, pof induced neurodegenerative diseases hallmarks like phospho-serine129 alpha-synuclein, tyrosine hydroxylase decrease in striatum, tau accumulation in hippocampus. |
2019-09-09 |
2023-08-13 |
mouse |
| b' Ivan Zaletel, Marija Schwirtlich, Milka Perovi\\xc4\\x87, Mirna Jovanovi\\xc4\\x87, Milena Stevanovi\\xc4\\x87, Selma Kanazir, Nela Pu\\xc5\\xa1ka\\xc5\\xa. Early Impairments of Hippocampal Neurogenesis in 5xFAD Mouse Model of Alzheimer\'s Disease Are Associated with Altered Expression of SOXB Transcription Factors. Journal of Alzheimer\'s disease : JAD. vol 65. issue 3. 2019-08-19. PMID:30103323.' |
dysregulation of neurogenesis in the subgranular zone (sgz) of the hippocampal dentate gyrus has been related to cognitive deficits and memory loss in neurodegenerative diseases, such as alzheimer's disease (ad). |
2019-08-19 |
2023-08-13 |
mouse |
| Laura Rozenblum, Marie-Odile Habert, Nadya Pyatigorskaya, Carole Roue-Jagot, Aurélie Ka. FDG PET/MRI Findings Pointing Toward a Gayet-Wernicke Encephalopathy. Clinical nuclear medicine. vol 44. issue 7. 2019-08-15. PMID:31058688. |
metabolism showed no pattern of neurodegenerative disease, but a severe decrease in hippocampus and mammillary bodies (mbs). |
2019-08-15 |
2023-08-13 |
Not clear |
| Claire R Galloway, Kaushik Ravipati, Suyashi Singh, Evan P Lebois, Robert M Cohen, Allan I Levey, Joseph R Mann. Hippocampal place cell dysfunction and the effects of muscarinic M Hippocampus. vol 28. issue 8. 2019-07-16. PMID:29742799. |
hippocampal place cell dysfunction and the effects of muscarinic m alzheimer's disease (ad) is a neurodegenerative disease that disproportionately impacts memory and the hippocampus. |
2019-07-16 |
2023-08-13 |
rat |
| Jennifer M Coughlin, Stephanie Slania, Yong Du, Hailey B Rosenthal, Wojciech G Lesniak, Il Minn, Gwenn S Smith, Robert F Dannals, Hiroto Kuwabara, Dean F Wong, Yuchuan Wang, Andrew G Horti, Martin G Pompe. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 59. issue 10. 2019-07-08. PMID:29496987. |
reduced density of the α4β2 nicotinic acetylcholine receptor (α4β2-nachr) in the cortex and hippocampus of the human brain has been reported in aging and patients with neurodegenerative disease. |
2019-07-08 |
2023-08-13 |
human |
| P C Bello-Medina, R A Prado-Alcalá, S Rivas-Arancibi. Effect of Ozone Exposure on Dendritic Spines of CA1 Pyramidal Neurons of the Dorsal Hippocampus and on Object-place Recognition Memory in Rats. Neuroscience. vol 402. 2019-06-21. PMID:30685541. |
these results indicate that chronic ozone exposure produces a loss in the inputs of ca1 neurons of the dorsal hippocampus, which may be the source of the cognitive deficits observed in the object-place recognition task, as indicated by the decrease in density of dendritic spines; these alterations are similar to those reported in some neurodegenerative diseases such as alzheimer's disease. |
2019-06-21 |
2023-08-13 |
rat |
| Cindy Chi-Ching Pang, Clemens Kiecker, John T O'Brien, Wendy Noble, Raymond Chuen-Chung Chan. Ammon's Horn 2 (CA2) of the Hippocampus: A Long-Known Region with a New Potential Role in Neurodegeneration. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. vol 25. issue 2. 2019-06-19. PMID:29865938. |
here, we review understanding of hippocampus and ca2 ontogenesis, together with basic and clinical findings about the potential role of this region in neurodegenerative disease. |
2019-06-19 |
2023-08-13 |
Not clear |
| Yu K Komleva, O L Lopatina, Ya V Gorina, A I Chernykh, A N Shuvaev, A B Salmin. [Early changes in hyppocampal neurogenesis induced by soluble Ab1-42 oligomers]. Biomeditsinskaia khimiia. vol 64. issue 4. 2019-04-03. PMID:30135279. |
as awareness of the importance of the pre-symptom phase in neurodegenerative diseases grows in the context of early diagnosis and pathogenesis, we analyzed the critical periods of adult hippocampal neurogenesis at an early stage under the action of soluble ab1-42 beta-amyloid. |
2019-04-03 |
2023-08-13 |
mouse |