| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Md Habibur Rahman, Rokeya Akter, Tanima Bhattacharya, Mohamed M Abdel-Daim, Saad Alkahtani, Mohammed W Arafah, Norah S Al-Johani, Norah M Alhoshani, Nora Alkeraishan, Alhanof Alhenaky, Omar H Abd-Elkader, Hesham R El-Seedi, Deepak Kaushik, Vineet Mitta. Resveratrol and Neuroprotection: Impact and Its Therapeutic Potential in Alzheimer's Disease. Frontiers in pharmacology. vol 11. 2021-01-19. PMID:33456444. |
alzheimer's disease (ad) is a progressive cortex and hippocampal neurodegenerative disease which ultimately causes cognitively impaired decline in patients. |
2021-01-19 |
2023-08-13 |
Not clear |
| Hong-He Xiao, Ming-Bo Zhang, Jun-Ting Xu, Yan Deng, Ning Li, Peng Gao, Yan Li, Liang Kong, Wan-Yi Li, Ji-Cong Chen, Hong-Yan Li, Guo-Shun Shan, He Tai, Jing-Xian Yan. Icarisid II promotes proliferation and neuronal differentiation of neural stem cells via activating Wnt/β-catenin signaling pathway. Phytotherapy research : PTR. 2021-01-17. PMID:33455039. |
mobilization of hippocampal neurogenesis has been regarded as a promising therapeutic approach to restore injured neurons in neurodegenerative diseases including alzheimer's disease (ad). |
2021-01-17 |
2023-08-13 |
human |
| María F Zappa Villar, Juliette López Hanotte, Joaquín Pardo, Gustavo R Morel, Guillermo Mazzolini, Mariana G García, Paula C Reggian. Mesenchymal Stem Cells Therapy Improved the Streptozotocin-Induced Behavioral and Hippocampal Impairment in Rats. Molecular neurobiology. vol 57. issue 2. 2020-11-05. PMID:31399955. |
these findings, by showing that intravenous injection of human msc restores behavioral and hippocampal alterations in experimental sad, support the potential use of msc therapy for the treatment of neurodegenerative diseases. |
2020-11-05 |
2023-08-13 |
human |
| Maria Grazia Piancino, Alessandro Tortarolo, Antonella Polimeni, Ennio Bramanti, Placido Bramant. Altered mastication adversely impacts morpho-functional features of the hippocampus: A systematic review on animal studies in three different experimental conditions involving the masticatory function. PloS one. vol 15. issue 8. 2020-10-15. PMID:32817680. |
the emerging role of chewing in the preservation of hippocampal trophism, neurogenesis and synaptic activity is worthy of interest and may contribute to the study of neurodegenerative diseases in new and potentially relevant ways. |
2020-10-15 |
2023-08-13 |
Not clear |
| Andrew O'Shea, Ronald A Cohen, Eric C Porges, Nicole R Nissim, Adam J Wood. Cognitive Aging and the Hippocampus in Older Adults. Frontiers in aging neuroscience. vol 8. 2020-10-01. PMID:28008314. |
while age-related decline in hippocampal volume is well documented, most of our knowledge about hippocampal structure-function relationships was discovered in the context of neurological and neurodegenerative diseases. |
2020-10-01 |
2023-08-13 |
human |
| Yoshiki Takamatsu, Wakako Koike, Takato Takenouchi, Shuei Sugama, Jianshe Wei, Masaaki Waragai, Kazunari Sekiyama, Makoto Hashimot. Protection against neurodegenerative disease on Earth and in space. NPJ microgravity. vol 2. 2020-10-01. PMID:28725728. |
we particularly noted a proteomics paper showing that levels of hippocampal proteins, including β-synuclein and carboxyl-terminal ubiquitin hydrolase l1, which have been linked to familial neurodegenerative diseases, were significantly decreased in the hippocampus of mice subjected to hindlimb suspension, a model of microgravity. |
2020-10-01 |
2023-08-13 |
mouse |
| Xuetong Wang, Yang Yu, Weina Zhao, Qiongling Li, Xinwei Li, Shuyu Li, Changhao Yin, Ying Ha. Altered Whole-Brain Structural Covariance of the Hippocampal Subfields in Subcortical Vascular Mild Cognitive Impairment and Amnestic Mild Cognitive Impairment Patients. Frontiers in neurology. vol 9. 2020-10-01. PMID:29872419. |
the hippocampal subfields are differently affected by many neurodegenerative diseases, especially mild cognitive impairment (mci). |
2020-10-01 |
2023-08-13 |
Not clear |
| Gemma McGregor, Jenni Harve. Regulation of Hippocampal Synaptic Function by the Metabolic Hormone, Leptin: Implications for Health and Neurodegenerative Disease. Frontiers in cellular neuroscience. vol 12. 2020-10-01. PMID:30386207. |
regulation of hippocampal synaptic function by the metabolic hormone, leptin: implications for health and neurodegenerative disease. |
2020-10-01 |
2023-08-13 |
Not clear |
| Robert S Seminara, Charan Jeet, Sharmi Biswas, Bushra Kanwal, Waleed Iftikhar, Md Sakibuzzaman, Ian H Rutkofsk. The Neurocognitive Effects of Ghrelin-induced Signaling on the Hippocampus: A Promising Approach to Alzheimer's Disease. Cureus. vol 10. issue 9. 2020-10-01. PMID:30443455. |
the team explored the possible therapeutic indications of ghrelin by looking at studies conducted with a specific neurodegenerative disease known to target the hippocampus. |
2020-10-01 |
2023-08-13 |
Not clear |
| b' Cristhyane Costa de Aquino, Ricardo A Leit\\xc3\\xa3o, Lu\\xc3\\xads A Oliveira Alves, Vanessa Coelho-Santos, Richard L Guerrant, Carlos F Ribeiro, Jo\\xc3\\xa3o O Malva, Ana P Silva, Reinaldo B Ori\\xc3\\xa. Effect of Hypoproteic and High-Fat Diets on Hippocampal Blood-Brain Barrier Permeability and Oxidative Stress. Frontiers in nutrition. vol 5. 2020-10-01. PMID:30687711.' |
noteworthy, neuroinflammatory events in the hippocampus may cause neuronal malfunction leading to cognitive deficits and long-term persistence of this phenomenon may contribute to age-related neurodegenerative diseases. |
2020-10-01 |
2023-08-13 |
mouse |
| Valeria Bortolotto, Heather Bondi, Bruna Cuccurazzu, Maurizio Rinaldi, Pier Luigi Canonico, Mariagrazia Grill. Salmeterol, a β2 Adrenergic Agonist, Promotes Adult Hippocampal Neurogenesis in a Region-Specific Manner. Frontiers in pharmacology. vol 10. 2020-10-01. PMID:31572182. |
deregulation of adult hippocampal neurogenesis (ahng) occurs in several neuropsychiatric and neurodegenerative diseases, including major depression, and represents a potential therapeutic target. |
2020-10-01 |
2023-08-13 |
Not clear |
| Maher Kurdi, Esther Chin, Lee Cyn An. Granulovacuolar Degeneration in Hippocampus of Neurodegenerative Diseases: Quantitative Study. Journal of neurodegenerative diseases. vol 2016. 2020-09-30. PMID:27843674. |
granulovacuolar degeneration in hippocampus of neurodegenerative diseases: quantitative study. |
2020-09-30 |
2023-08-13 |
Not clear |
| Daniele Lana, Filippo Ugolini, Daniele Nosi, Gary L Wenk, Maria G Giovannin. Alterations in the Interplay between Neurons, Astrocytes and Microglia in the Rat Dentate Gyrus in Experimental Models of Neurodegeneration. Frontiers in aging neuroscience. vol 9. 2020-09-30. PMID:28955220. |
the hippocampus is negatively affected by aging and neurodegenerative diseases leading to impaired learning and memory abilities. |
2020-09-30 |
2023-08-13 |
rat |
| Ayodele Jacob Akinyemi, Philip Adeyemi Adeniy. Effect of Essential Oils from Ginger ( Journal of toxicology. vol 2018. 2020-09-30. PMID:30402094. |
the result revealed that essential oil from ginger and turmeric rhizomes exerts anti-inflammatory effect by preventing alterations of some cytokines/inflammatory biomarkers (il-6, il-10 and tnf-alpha) levels and inhibits both hippocampus and prefrontal cortex acetylcholinesterase (ache) and adenosine deaminase (ada) activities (important enzymes relevant in the management/prevention of neurodegenerative diseases) in cd treated rats. |
2020-09-30 |
2023-08-13 |
rat |
| Qinghua Zeng, Zhimin Long, Min Feng, Yueyang Zhao, Shifang Luo, Kejian Wang, Yingxiong Wang, Guang Yang, Guiqiong H. Valproic Acid Stimulates Hippocampal Neurogenesis Frontiers in aging neuroscience. vol 11. 2020-09-30. PMID:30971911. |
valproic acid stimulates hippocampal neurogenesis alzheimer's disease (ad) is an age-related neurodegenerative disease characterized by the deposition of amyloid-β (aβ) peptides and neurofibrillary tangles (nfts) and massive loss of neuronal cells in the brain. |
2020-09-30 |
2023-08-13 |
mouse |
| Ju Zeng, Bin Cheng, Yan Huang, Xiaorui Zhang, Chen Wang, Na Sun, Gang Liu, Xiaorui Cheng, Yongxiang Zhang, Wenxia Zho. Active Fraction Combination from Liuwei Dihuang Decoction (LW-AFC) Alleviated the LPS-Induced Long-Term Potentiation Impairment and Glial Cells Activation in Hippocampus of Mice by Modulating Immune Responses. Evidence-based complementary and alternative medicine : eCAM. vol 2019. 2020-09-30. PMID:31636681. |
neuroinflammation is known as a typical feature associated with many neurodegenerative diseases including alzheimer's disease (ad) and impairs the synaptic plasticity of the hippocampus. |
2020-09-30 |
2023-08-13 |
mouse |
| María Llorens-Martí. Exercising New Neurons to Vanquish Alzheimer Disease. Brain plasticity (Amsterdam, Netherlands). vol 4. issue 1. 2020-09-29. PMID:30564550. |
this review article summarizes current evidence supporting the putative therapeutic potential of ee and physical exercise to increase ahn and hippocampal plasticity both under physiological and pathological circumstances, with a special emphasis on neurodegenerative diseases and ad. |
2020-09-29 |
2023-08-13 |
Not clear |
| Paula Adler, Cheng-Kang Chiang, Janice Mayne, Zhibin Ning, Xu Zhang, Bo Xu, Hai-Ying Mary Cheng, Daniel Figey. Aging Disrupts the Circadian Patterns of Protein Expression in the Murine Hippocampus. Frontiers in aging neuroscience. vol 11. 2020-09-28. PMID:32009941. |
these insights into aging-induced changes in the hippocampal proteome provide a framework for understanding how the age-dependent circadian decline may contribute to cognitive impairment and the development of neurodegenerative diseases during aging. |
2020-09-28 |
2023-08-13 |
mouse |
| Qingfa Chen, Hao Song, Chuanguo Liu, Jun Xu, Chuanfei Wei, Wei Wang, Fabin Ha. The Interaction of EphA4 With PDGFRβ Regulates Proliferation and Neuronal Differentiation of Neural Progenitor Cells Frontiers in aging neuroscience. vol 12. 2020-09-28. PMID:32116646. |
the interaction of epha4 with pdgfrβ regulates proliferation and neuronal differentiation of neural progenitor cells neural progenitor cells (npcs) have great potentials in cell replacement therapy for neurodegenerative diseases, such as alzheimer's disease (ad), by promoting neurogenesis associated with hippocampal memory improvement. |
2020-09-28 |
2023-08-13 |
mouse |
| Roberta Andrejew, Ágatha Oliveira-Giacomelli, Deidiane Elisa Ribeiro, Talita Glaser, Vanessa Fernandes Arnaud-Sampaio, Claudiana Lameu, Henning Ulric. The P2X7 Receptor: Central Hub of Brain Diseases. Frontiers in molecular neuroscience. vol 13. 2020-09-28. PMID:32848594. |
the p2x7 receptor is widely expressed in the cns, such as frontal cortex, hippocampus, amygdala and striatum, regions involved in neurodegenerative diseases and psychiatric disorders. |
2020-09-28 |
2023-08-13 |
Not clear |