| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Md Ataur Rahman, M D Hasanur Rahman, A N M Mamun-Or-Rashid, Hongik Hwang, Sooyoung Chung, Bonglee Kim, Hyewhon Rhi. Autophagy Modulation in Aggresome Formation: Emerging Implications and Treatments of Alzheimer's Disease. Biomedicines. vol 10. issue 5. 2022-05-28. PMID:35625764. |
alzheimer's disease (ad) is one of the most prevailing neurodegenerative diseases in the world, which is characterized by memory dysfunction and the formation of tau and amyloid β (aβ) aggregates in multiple brain regions, including the hippocampus and cortex. |
2022-05-28 |
2023-08-13 |
Not clear |
| Hauke Thiesler, Melike Küçükerden, Lina Gretenkort, Iris Röckle, Herbert Hildebrand. News and Views on Polysialic Acid: From Tumor Progression and Brain Development to Psychiatric Disorders, Neurodegeneration, Myelin Repair and Immunomodulation. Frontiers in cell and developmental biology. vol 10. 2022-05-26. PMID:35617589. |
we then elaborate on the implications of polysia functions in hippocampal plasticity, learning and memory of mice in light of recently described polysia changes related to altered neurogenesis in the aging human brain and in neurodegenerative disease. |
2022-05-26 |
2023-08-13 |
mouse |
| J Terreros-Roncal, E P Moreno-Jiménez, M Flor-García, C B Rodríguez-Moreno, M F Trinchero, B Márquez-Valadez, F Cafini, A Rábano, M Llorens-Martí. Response to Comment on "Impact of neurodegenerative diseases on human adult hippocampal neurogenesis". Science (New York, N.Y.). vol 376. issue 6590. 2022-05-03. PMID:35504021. |
response to comment on "impact of neurodegenerative diseases on human adult hippocampal neurogenesis". |
2022-05-03 |
2023-08-13 |
human |
| Arturo Alvarez-Buylla, Arantxa Cebrian-Silla, Shawn F Sorrells, Marcos Assis Nascimento, Mercedes F Paredes, Jose Manuel Garcia-Verdugo, Zhengang Yang, Eric J Huan. Comment on "Impact of neurodegenerative diseases on human adult hippocampal neurogenesis". Science (New York, N.Y.). vol 376. issue 6590. 2022-04-14. PMID:35420933. |
comment on "impact of neurodegenerative diseases on human adult hippocampal neurogenesis". |
2022-04-14 |
2023-08-13 |
human |
| Jon I Arellano, Alvaro Duque, Pasko Raki. Comment on "Impact of neurodegenerative diseases on human adult hippocampal neurogenesis". Science (New York, N.Y.). vol 376. issue 6590. 2022-04-14. PMID:35420939. |
comment on "impact of neurodegenerative diseases on human adult hippocampal neurogenesis". |
2022-04-14 |
2023-08-13 |
human |
| J Terreros-Roncal, E P Moreno-Jiménez, M Flor-García, C B Rodríguez-Moreno, M F Trinchero, B Márquez-Valadez, F Cafini, A Rábano, M Llorens-Martí. Response to Comment on "Impact of neurodegenerative diseases on human adult hippocampal neurogenesis". Science (New York, N.Y.). vol 376. issue 6590. 2022-04-14. PMID:35420954. |
response to comment on "impact of neurodegenerative diseases on human adult hippocampal neurogenesis". |
2022-04-14 |
2023-08-13 |
human |
| Anna N Senko, Rupert W Overall, Jan Silhavy, Petr Mlejnek, Hana Malínská, Martina Hüttl, Irena Marková, Klaus S Fabel, Lu Lu, Ales Stuchlik, Robert W Williams, Michal Pravenec, Gerd Kemperman. Systems genetics in the rat HXB/BXH family identifies Tti2 as a pleiotropic quantitative trait gene for adult hippocampal neurogenesis and serum glucose. PLoS genetics. vol 18. issue 4. 2022-04-04. PMID:35377872. |
neurogenesis in the adult hippocampus contributes to learning and memory in the healthy brain but is dysregulated in metabolic and neurodegenerative diseases. |
2022-04-04 |
2023-08-13 |
rat |
| Poornima D E Weerasinghe-Mudiyanselage, Mary Jasmin Ang, Sohi Kang, Joong-Sun Kim, Changjong Moo. Structural Plasticity of the Hippocampus in Neurodegenerative Diseases. International journal of molecular sciences. vol 23. issue 6. 2022-03-25. PMID:35328770. |
structural plasticity of the hippocampus in neurodegenerative diseases. |
2022-03-25 |
2023-08-13 |
Not clear |
| Poornima D E Weerasinghe-Mudiyanselage, Mary Jasmin Ang, Sohi Kang, Joong-Sun Kim, Changjong Moo. Structural Plasticity of the Hippocampus in Neurodegenerative Diseases. International journal of molecular sciences. vol 23. issue 6. 2022-03-25. PMID:35328770. |
structural modifications in the hippocampus underpin several neurodegenerative diseases that exhibit cognitive and emotional dysregulation. |
2022-03-25 |
2023-08-13 |
Not clear |
| Poornima D E Weerasinghe-Mudiyanselage, Mary Jasmin Ang, Sohi Kang, Joong-Sun Kim, Changjong Moo. Structural Plasticity of the Hippocampus in Neurodegenerative Diseases. International journal of molecular sciences. vol 23. issue 6. 2022-03-25. PMID:35328770. |
this article reviews the findings of several preclinical and clinical studies about the role of structural plasticity in the hippocampus in neurodegenerative diseases, including alzheimer's disease, parkinson's disease, huntington's disease, and multiple sclerosis. |
2022-03-25 |
2023-08-13 |
Not clear |
| Poornima D E Weerasinghe-Mudiyanselage, Mary Jasmin Ang, Sohi Kang, Joong-Sun Kim, Changjong Moo. Structural Plasticity of the Hippocampus in Neurodegenerative Diseases. International journal of molecular sciences. vol 23. issue 6. 2022-03-25. PMID:35328770. |
in this study, literature was surveyed using google scholar, pubmed, web of science, and scopus, to review the mechanisms that underlie the alterations in the structural plasticity of the hippocampus in neurodegenerative diseases. |
2022-03-25 |
2023-08-13 |
Not clear |
| Poornima D E Weerasinghe-Mudiyanselage, Mary Jasmin Ang, Sohi Kang, Joong-Sun Kim, Changjong Moo. Structural Plasticity of the Hippocampus in Neurodegenerative Diseases. International journal of molecular sciences. vol 23. issue 6. 2022-03-25. PMID:35328770. |
this review summarizes the role of structural plasticity in the hippocampus for the etiopathogenesis of neurodegenerative diseases and identifies the current focus and gaps in knowledge about hippocampal dysfunctions. |
2022-03-25 |
2023-08-13 |
Not clear |
| Travis E Hodges, Tanvi A Puri, Samantha A Blankers, Wansu Qiu, Liisa A M Gale. Steroid hormones and hippocampal neurogenesis in the adult mammalian brain. Vitamins and hormones. vol 118. 2022-02-19. PMID:35180925. |
hippocampal neurogenesis persists across the lifespan in many species, including rodents and humans, and is associated with cognitive performance and the pathogenesis of neurodegenerative disease and psychiatric disorders. |
2022-02-19 |
2023-08-13 |
Not clear |
| Jennifer Mytyc. Actions of Klotho on hippocampal neuronal cells. Vitamins and hormones. vol 118. 2022-02-19. PMID:35180928. |
however, recent studies link alterations in hippocampal klotho expression with cognitive impairment and neurodegenerative diseases. |
2022-02-19 |
2023-08-13 |
Not clear |
| Qiu-Ying Yan, Jian-Lu Lv, Xing-Yi Shen, Xing-Nan Ou-Yang, Juan-Zhen Yang, Rui-Fang Nie, Jian Lu, Yu-Jie Huang, Jia-Ying Wang, Xu She. Patchouli alcohol as a selective estrogen receptor β agonist ameliorates AD-like pathology of APP/PS1 model mice. Acta pharmacologica Sinica. 2022-01-29. PMID:35091686. |
estrogen receptor (er) α is mainly expressed in the mammary gland and other reproductive organs like uterus while erβ is largely distributed in the hippocampus and cardiovascular system, suggesting that erβ selective agonist is a valuable drug against neurodegenerative diseases with low tendency in inducing cancers of breast and other reproductive organs. |
2022-01-29 |
2023-08-13 |
mouse |
| José V Manjón, José E Romero, Pierrick Coup. A novel deep learning based hippocampus subfield segmentation method. Scientific reports. vol 12. issue 1. 2022-01-26. PMID:35079061. |
the automatic assessment of hippocampus volume is an important tool in the study of several neurodegenerative diseases such as alzheimer's disease. |
2022-01-26 |
2023-08-13 |
Not clear |
| Cui Wang, Ji-Cong Chen, Hong-He Xiao, Liang Kong, Yu-Meng Zhao, Yu Tian, He Li, Jin-Ming Tian, Lin Cui, Cai-Ming Wen, Yi-Jun Shi, Jing-Xian Yang, De-Jing Shan. Jujuboside A promotes proliferation and neuronal differentiation of APPswe-overexpressing neural stem cells by activating Wnt/β-catenin signaling pathway. Neuroscience letters. 2022-01-25. PMID:35077846. |
mobilization of hippocampal neurogenesis has been considered as a potential strategy for the treatment of neurodegenerative diseases, including alzheimer's disease (ad). |
2022-01-25 |
2023-08-13 |
Not clear |
| Ayland C Letsinger, Zhenglin Gu, Jerrel L Yake. α7 nicotinic acetylcholine receptors in the hippocampal circuit: taming complexity. Trends in neurosciences. 2021-12-17. PMID:34916082. |
the α7 nicotinic ach receptor (nachr) subtype is highly expressed throughout the hippocampus, has the highest calcium permeability compared with other subtypes of nachrs, and is of high therapeutic interest due to its association with a variety of neurological disorders and neurodegenerative diseases. |
2021-12-17 |
2023-08-13 |
Not clear |
| Malk Eun Pak, You-Chang Oh, Yeo Jin Park, Jae Kwang Kim, Min-Gyeong Shin, Jong Hyuk Yoon, Younghoon G. Banhasasim-Tang Ameliorates Spatial Memory by Suppressing Oxidative Stress through Regulation of ERK/p38 Signaling in Hippocampus of Mice. Oxidative medicine and cellular longevity. vol 2021. 2021-12-13. PMID:34900088. |
therefore, our data indicated that bhs may reduce oxidative stress through regulation of erk-creb and p38-p53 signaling in the hippocampus, resulting in decreased neuronal damage and improved memory in rodent models of neurodegenerative disease. |
2021-12-13 |
2023-08-13 |
mouse |
| Ignacio Jure, Eugenia Falomir Lockhart, Alejandro F De Nicola, María Jose Bellini, Florencia Labombard. IGF1 Gene Therapy Reversed Cognitive Deficits and Restored Hippocampal Alterations After Chronic Spinal Cord Injury. Molecular neurobiology. vol 58. issue 12. 2021-12-03. PMID:34463925. |
in summary, rad-igf1 gene therapy might surge as a new therapeutic strategy for patients with hippocampal microglial alterations and cognitive deficits such as those with spinal cord injury and other neurodegenerative diseases. |
2021-12-03 |
2023-08-13 |
Not clear |