| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cindy Santiago-Castañeda, Marysol Segovia-Oropeza, Luis Concha, Sandra Adela Orozco-Suárez, Luisa Roch. Propylparaben Reduces the Long-Term Consequences in Hippocampus Induced by Traumatic Brain Injury in Rats: Its Implications as Therapeutic Strategy to Prevent Neurodegenerative Diseases. Journal of Alzheimer's disease : JAD. vol 82. issue s1. 2021-09-23. PMID:33185606. |
on the other hand, studies support that propylparaben (ppb) induces hippocampal neuroprotection in neurodegenerative diseases. |
2021-09-23 |
2023-08-13 |
rat |
| J Burillo, M Fernández-Rhodes, M Piquero, P López-Alvarado, J C Menéndez, B Jiménez, C González-Blanco, P Marqués, C Guillén, M Benit. Human amylin aggregates release within exosomes as a protective mechanism in pancreatic β cells: Pancreatic β-hippocampal cell communication. Biochimica et biophysica acta. Molecular cell research. vol 1868. issue 5. 2021-09-17. PMID:33515645. |
in summary, our results show that harmful accumulation of hiapp in pancreatic β cells may be detoxified by the release of exosomes, which may be captured by endocytosis mechanism damaging neuronal hippocampal cells, which suggest an underlying molecular mechanism to the link between type 2 diabetes and neurodegenerative diseases. |
2021-09-17 |
2023-08-13 |
human |
| Kim Blom, Huiberdina L Koek, Maarten H T Zwartbol, Rashid Ghaznawi, Hugo J Kuijf, Theo D Witkamp, Jeroen Hendrikse, Geert Jan Biessels, Mirjam I Geerling. Vascular Risk Factors of Hippocampal Subfield Volumes in Persons without Dementia: The Medea 7T Study. Journal of Alzheimer's disease : JAD. vol 77. issue 3. 2021-09-09. PMID:32925029. |
knowing if vascular risk factors contribute to hippocampal subfield atrophy may improve our understanding of vascular contributions to neurodegenerative diseases. |
2021-09-09 |
2023-08-13 |
Not clear |
| Md Ataur Rahman, Md Abdul Hannan, Md Jamal Uddin, Md Saidur Rahman, Md Mamunur Rashid, Bonglee Ki. Exposure to Environmental Arsenic and Emerging Risk of Alzheimer's Disease: Perspective Mechanisms, Management Strategy, and Future Directions. Toxics. vol 9. issue 8. 2021-08-31. PMID:34437506. |
alzheimer's disease (ad) is one of the most prevailing neurodegenerative diseases, characterized by memory dysfunction and the presence of hyperphosphorylated tau and amyloid β (aβ) aggregates in multiple brain regions, including the hippocampus and cortex. |
2021-08-31 |
2023-08-13 |
human |
| L E M Wisse, S Ravikumar, R Ittyerah, S Lim, J Lane, M L Bedard, L Xie, S R Das, T Schuck, M Grossman, E B Lee, M D Tisdall, K Prabhakaran, J A Detre, G Mizsei, J Q Trojanowski, E Artacho-Pérula, M M de Iñiguez de Onzono Martin, M M Arroyo-Jiménez, M Muñoz Lopez, F J Molina Romero, M P Marcos Rabal, S Cebada Sánchez, J C Delgado González, C de la Rosa Prieto, M Córcoles Parada, D A Wolk, D J Irwin, R Insausti, P A Yushkevic. Downstream effects of polypathology on neurodegeneration of medial temporal lobe subregions. Acta neuropathologica communications. vol 9. issue 1. 2021-08-23. PMID:34289895. |
tau, tar dna-binding protein 43 (tdp-43), amyloid-β and α-synuclein pathology were rated on a scale of 0 (absent)-3 (severe) in the hippocampus and entorhinal cortex (erc) of 58 individuals with and without neurodegenerative diseases (median age 75.0 years, 60.3% male). |
2021-08-23 |
2023-08-13 |
Not clear |
| Xiaolei Wu, Qi Shen, Zhan Zhang, Di Zhang, Ying Gu, Da Xin. Photoactivation of TGFβ/SMAD signaling pathway ameliorates adult hippocampal neurogenesis in Alzheimer's disease model. Stem cell research & therapy. vol 12. issue 1. 2021-07-12. PMID:34116709. |
adult hippocampal neurogenesis (ahn) is restricted under the pathological conditions of neurodegenerative diseases, especially in alzheimer's disease (ad). |
2021-07-12 |
2023-08-13 |
Not clear |
| Emily E Noble, Christine A Olson, Elizabeth Davis, Linda Tsan, Yen-Wei Chen, Ruth Schade, Clarissa Liu, Andrea Suarez, Roshonda B Jones, Claire de La Serre, Xia Yang, Elaine Y Hsiao, Scott E Kanosk. Gut microbial taxa elevated by dietary sugar disrupt memory function. Translational psychiatry. vol 11. issue 1. 2021-06-28. PMID:33790226. |
hippocampus transcriptome analyses revealed that early life sugar consumption altered gene expression in intracellular kinase and synaptic neurotransmitter signaling pathways, whereas parabacteroides microbial enrichment altered gene expression in pathways associated with metabolic function, neurodegenerative disease, and dopaminergic signaling. |
2021-06-28 |
2023-08-13 |
rat |
| Mariam Rizk, Justin Vu, Zhi Zhan. Impact of pediatric traumatic brain injury on hippocampal neurogenesis. Neural regeneration research. vol 16. issue 5. 2021-06-23. PMID:33229731. |
alterations in adult hippocampal neurogenesis are associated with a variety of neurological and neurodegenerative diseases, including tbi. |
2021-06-23 |
2023-08-13 |
Not clear |
| Josiane Budni, Arleide Braga Brandão, Sabrina da Silva, Michelle Lima Garcez, Francielle Mina, Tatiani Bellettini-Santos, Gabriel Casagrande Zabot, Eduarda Behenck Medeiros, Giselli Scaini, Jade de Oliveira, Emílio Luiz Streck, João Queved. Oral administration of D-galactose increases brain tricarboxylic acid cycle enzymes activities in Wistar rats. Metabolic brain disease. vol 36. issue 5. 2021-06-22. PMID:33616841. |
d-gal administration orally administered modulated tca cycle enzymes and ck activities in the prefrontal cortex and hippocampus, which were also observed in aging and neurodegenerative diseases. |
2021-06-22 |
2023-08-13 |
rat |
| Breno da Silveira Souza, Katia M Poloni, Ricardo J Ferrar. Detector of 3-D salient points based on the dual-tree complex wavelet transform for the positioning of hippocampi meshes in magnetic resonance images. Journal of neuroscience methods. vol 341. 2021-06-21. PMID:32512218. |
the analysis of brain structures (such as the hippocampus) can help in the diagnosis and follow-up of neurodegenerative diseases like alzheimer's. |
2021-06-21 |
2023-08-13 |
Not clear |
| Wen Tang, Zhaoyou Meng, Ning Li, Yiyan Liu, Li Li, Dongfeng Chen, Yang Yan. Roles of Gut Microbiota in the Regulation of Hippocampal Plasticity, Inflammation, and Hippocampus-Dependent Behaviors. Frontiers in cellular and infection microbiology. vol 10. 2021-06-17. PMID:33585279. |
the hippocampus is the center of learning and memory, and plays a pivotal role in neurodegenerative diseases, such as alzheimer's disease (ad). |
2021-06-17 |
2023-08-13 |
mouse |
| Joseph M Schul. The Potential of Induced Pluripotent Stem Cells to Treat and Model Alzheimer's Disease. Stem cells international. vol 2021. 2021-06-15. PMID:34122554. |
an estimated 6.2 million americans aged 65 or older are currently living with alzheimer's disease (ad), a neurodegenerative disease that disrupts an individual's ability to function independently through the degeneration of key regions in the brain, including but not limited to the hippocampus, the prefrontal cortex, and the motor cortex. |
2021-06-15 |
2023-08-13 |
human |
| Hansruedi Büele. Mitochondrial and Autophagic Regulation of Adult Neurogenesis in the Healthy and Diseased Brain. International journal of molecular sciences. vol 22. issue 7. 2021-06-09. PMID:33805219. |
defects of adult hippocampal neurogenesis have been linked to cognitive decline and dysfunction during natural aging and in neurodegenerative diseases, as well as psychological stress-induced mood disorders. |
2021-06-09 |
2023-08-13 |
Not clear |
| Jessica M V Pino, Erika S Nishiduka, Márcio H M da Luz, Vitória F Silva, Hanna K M Antunes, Alexandre K Tashima, Pedro L R Guedes, Altay A L de Souza, Kil S Le. Iron-deficient diet induces distinct protein profile related to energy metabolism in the striatum and hippocampus of adult rats. Nutritional neuroscience. 2021-05-18. PMID:32183604. |
in the hippocampus, a larger portion of proteins related to oxidative phosphorylation and neurodegenerative diseases were altered. |
2021-05-18 |
2023-08-13 |
rat |
| Zizhen Si, Xue Wang, Yuchun Kang, Xidi Wang, Changhui Sun, Yuanxin Li, Jiakun Xu, Jiajia Wu, Zhujun Zhang, Ling Li, Yahui Peng, Jihong Li, Chongran Sun, Yang Hui, Xu Ga. Heme Oxygenase 1 Inhibits Adult Neural Stem Cells Proliferation and Survival via Modulation of Wnt/β-Catenin Signaling. Journal of Alzheimer's disease : JAD. vol 76. issue 2. 2021-05-07. PMID:32568195. |
adult hippocampal neurogenesis is critical for renewing hippocampal neural circuits and maintaining hippocampal cognitive function and is closely associated with age-related neurodegenerative diseases. |
2021-05-07 |
2023-08-13 |
Not clear |
| Daphne M P Naessens, Johannes G G Dobbe, Judith de Vos, Ed VanBavel, Erik N T P Bakke. Mapping Solute Clearance From the Mouse Hippocampus Using a 3D Imaging Cryomicrotome. Frontiers in neuroscience. vol 15. 2021-04-21. PMID:33867918. |
the hippocampus is susceptible to protein aggregation in neurodegenerative diseases such as alzheimer's disease. |
2021-04-21 |
2023-08-13 |
mouse |
| Samaneh Zarei, Mohammad Shafiei, Maryam Firouzi, Loghman Firoozpour, Kouros Divsalar, Ali Asadipour, Tahmineh Akbarzadeh, Alireza Foroumad. Design, synthesis and biological assessment of new 1-benzyl-4-((4-oxoquinazolin-3(4 Heliyon. vol 7. issue 4. 2021-04-21. PMID:33869871. |
design, synthesis and biological assessment of new 1-benzyl-4-((4-oxoquinazolin-3(4 alzheimer's disease (ad), is among the most growing neurodegenerative diseases, which is mainly caused by the acetylcholine neurotransmitter loss in the hippocampus and cortex. |
2021-04-21 |
2023-08-13 |
Not clear |
| Jung-Mi Oh, Jae Hoon Jeong, Sun Young Park, Sungkun Chu. Ginsenoside Compound K Induces Adult Hippocampal Proliferation and Survival of Newly Generated Cells in Young and Elderly Mice. Biomolecules. vol 10. issue 3. 2021-03-17. PMID:32210026. |
cognitive impairment can be associated with reduced adult hippocampal neurogenesis, and it may contribute to age-associated neurodegenerative diseases such as alzheimer's (ad). |
2021-03-17 |
2023-08-13 |
mouse |
| Genevieve Saw, Feng Ru Tan. Epigenetic Regulation of the Hippocampus, with Special Reference to Radiation Exposure. International journal of molecular sciences. vol 21. issue 24. 2021-03-15. PMID:33327654. |
several epigenetic factors, including dna methylation, histone modifications and non-coding rnas, have been shown to regulate the development and function of the hippocampus, and the alteration of epigenetic regulation may play important roles in the development of neurocognitive and neurodegenerative diseases. |
2021-03-15 |
2023-08-13 |
Not clear |
| Surina Frey, Rico Schieweck, Ignasi Forné, Axel Imhof, Tobias Straub, Bastian Popper, Michael A Kieble. Physical Activity Dynamically Regulates the Hippocampal Proteome along the Dorso-Ventral Axis. International journal of molecular sciences. vol 21. issue 10. 2021-02-12. PMID:32429128. |
in patients suffering from neuropsychiatric or neurodegenerative diseases, hippocampal signaling is altered causing cognitive defects. |
2021-02-12 |
2023-08-13 |
mouse |