| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cecilia P Kramar, Fernando Castillo-Díaz, Eduardo D Gigante, Jorge H Medina, M Flavia Barban. The late consolidation of an aversive memory is promoted by VTA dopamine release in the dorsal hippocampus. The European journal of neuroscience. vol 53. issue 3. 2021-06-28. PMID:33617053. |
in addition and consistent with previous findings showing that late post-training infusions of dopaminergic agents into the hippocampus modulate the long-term storage of aversive memories, we found that the photostimulation of dopaminergic vta fibers in the dorsal hippocampus 11-12 hr after cpa training was enough to transform a short-lasting long-term memory into a long-lasting one. |
2021-06-28 |
2023-08-13 |
rat |
| Joanna Peris, Madeline R Steck, Eric G Kraus. Oxytocin treatment for alcoholism: Potential neurocircuitry targets. Neuropharmacology. vol 171. 2021-06-25. PMID:32304701. |
in addition to dopamine neurons that project from ventral tegmental area (vta) to nucleus accumbens (nac) to signal positively reinforcing events, ot receptors (oxtr) are also expressed by dopamine neurons that project from vta to brain regions that can convey aversive properties of a stimulus. |
2021-06-25 |
2023-08-13 |
Not clear |
| Joanna Peris, Madeline R Steck, Eric G Kraus. Oxytocin treatment for alcoholism: Potential neurocircuitry targets. Neuropharmacology. vol 171. 2021-06-25. PMID:32304701. |
moreover, oxtr are expressed by non-dopaminergic neurons in the vta, such as gaba and glutamate neurons, which can both modulate the activity of dopamine vta neurons locally (in opposite directions) or can project to other brain regions, including the nac, where it can alter either positive reinforcement or aversion caused by ethanol. |
2021-06-25 |
2023-08-13 |
Not clear |
| Alberto Del Arco, Junchol Park, Bita Moghadda. Unanticipated Stressful and Rewarding Experiences Engage the Same Prefrontal Cortex and Ventral Tegmental Area Neuronal Populations. eNeuro. vol 7. issue 3. 2021-06-18. PMID:32385042. |
brain networks that mediate motivated behavior in the context of aversive and rewarding experiences involve the prefrontal cortex (pfc) and ventral tegmental area (vta). |
2021-06-18 |
2023-08-13 |
rat |
| Alberto Del Arco, Junchol Park, Bita Moghadda. Unanticipated Stressful and Rewarding Experiences Engage the Same Prefrontal Cortex and Ventral Tegmental Area Neuronal Populations. eNeuro. vol 7. issue 3. 2021-06-18. PMID:32385042. |
do the same or different pfc and vta neurons encode unanticipated aversive and appetitive experiences? |
2021-06-18 |
2023-08-13 |
rat |
| Alberto Del Arco, Junchol Park, Bita Moghadda. Unanticipated Stressful and Rewarding Experiences Engage the Same Prefrontal Cortex and Ventral Tegmental Area Neuronal Populations. eNeuro. vol 7. issue 3. 2021-06-18. PMID:32385042. |
these results reveal that aversive and rewarding experiences engage overlapping neuronal populations in the dmpfc and the vta. |
2021-06-18 |
2023-08-13 |
rat |
| Pedro A Pereira, Joana Coelho, Ana Silva, M Dulce Madeir. Effects of aging on the cholinergic innervation of the rat ventral tegmental area: A stereological study. Experimental gerontology. vol 148. 2021-06-02. PMID:33652122. |
dopamine neurons in the ventral tegmental area (vta) play a main role in processing both rewarding and aversive stimuli, and their response to salient stimuli is significantly shaped by afferents originating in the brainstem cholinergic nuclei. |
2021-06-02 |
2023-08-13 |
rat |
| David H Root, David J Barker, David J Estrin, Jorge A Miranda-Barrientos, Bing Liu, Shiliang Zhang, Hui-Ling Wang, Francois Vautier, Charu Ramakrishnan, Yoon Seok Kim, Lief Fenno, Karl Deisseroth, Marisela Morale. Distinct Signaling by Ventral Tegmental Area Glutamate, GABA, and Combinatorial Glutamate-GABA Neurons in Motivated Behavior. Cell reports. vol 32. issue 9. 2021-05-28. PMID:32877676. |
ventral tegmental area (vta) neurons play roles in reward and aversion. |
2021-05-28 |
2023-08-13 |
mouse |
| David H Root, David J Barker, David J Estrin, Jorge A Miranda-Barrientos, Bing Liu, Shiliang Zhang, Hui-Ling Wang, Francois Vautier, Charu Ramakrishnan, Yoon Seok Kim, Lief Fenno, Karl Deisseroth, Marisela Morale. Distinct Signaling by Ventral Tegmental Area Glutamate, GABA, and Combinatorial Glutamate-GABA Neurons in Motivated Behavior. Cell reports. vol 32. issue 9. 2021-05-28. PMID:32877676. |
we find that vta cell types have unique signaling patterns for reward, aversion, and learned cues. |
2021-05-28 |
2023-08-13 |
mouse |
| David H Root, David J Barker, David J Estrin, Jorge A Miranda-Barrientos, Bing Liu, Shiliang Zhang, Hui-Ling Wang, Francois Vautier, Charu Ramakrishnan, Yoon Seok Kim, Lief Fenno, Karl Deisseroth, Marisela Morale. Distinct Signaling by Ventral Tegmental Area Glutamate, GABA, and Combinatorial Glutamate-GABA Neurons in Motivated Behavior. Cell reports. vol 32. issue 9. 2021-05-28. PMID:32877676. |
whereas vta glutamate-transmitting neurons signal cues predicting reward, vta gaba-transmitting neurons signal cues predicting the absence of reward, and glutamate-gaba co-transmitting neurons signal rewarding and aversive outcomes without signaling learned cues related to those outcomes. |
2021-05-28 |
2023-08-13 |
mouse |
| Yolanda Campos-Jurado, Lucía Martí-Prats, Jose A Morón, Ana Polache, Luis Granero, Lucía Hipólit. Dose-dependent induction of CPP or CPA by intra-pVTA ethanol: Role of mu opioid receptors and effects on NMDA receptors. Progress in neuro-psychopharmacology & biological psychiatry. vol 100. 2021-04-28. PMID:31978422. |
here we sought to demonstrate, for the first time, that ethanol induces conditioned place preference or aversion (cpp or cpa) when administered locally into the ventral tegmental area (vta) and the associated role of mors. |
2021-04-28 |
2023-08-13 |
Not clear |
| Mykel A Robble, Mary E Bozsik, Daniel S Wheeler, Robert A Wheele. Learned avoidance requires VTA KOR-mediated reductions in dopamine. Neuropharmacology. vol 167. 2021-04-23. PMID:32057802. |
learned avoidance requires vta kor-mediated reductions in dopamine. |
2021-04-23 |
2023-08-13 |
rat |
| Mykel A Robble, Mary E Bozsik, Daniel S Wheeler, Robert A Wheele. Learned avoidance requires VTA KOR-mediated reductions in dopamine. Neuropharmacology. vol 167. 2021-04-23. PMID:32057802. |
to determine the necessity of vta kor activity in the regulation of dopamine signaling and avoidance, we tested the effects of vta kor blockade on real time dopaminergic responses to aversive stimuli and learned avoidance in male sprague-dawley rats. |
2021-04-23 |
2023-08-13 |
rat |
| Mykel A Robble, Mary E Bozsik, Daniel S Wheeler, Robert A Wheele. Learned avoidance requires VTA KOR-mediated reductions in dopamine. Neuropharmacology. vol 167. 2021-04-23. PMID:32057802. |
we found that blockade of vta kors attenuated aversion-induced reductions in dopamine, and this treatment also prevented avoidance following the aversive experience. |
2021-04-23 |
2023-08-13 |
rat |
| Elyssa B Margolis, Tanya L Wallace, Lori Jean Van Orden, William J Marti. Differential effects of novel kappa opioid receptor antagonists on dopamine neurons using acute brain slice electrophysiology. PloS one. vol 15. issue 12. 2021-01-13. PMID:33373369. |
kor agonists directly inhibit ventral tegmental area (vta) dopaminergic neurons, contributing to aversive responses (margolis et al. |
2021-01-13 |
2023-08-13 |
rat |
| David H Root, David J Estrin, Marisela Morale. Aversion or Salience Signaling by Ventral Tegmental Area Glutamate Neurons. iScience. vol 2. 2021-01-09. PMID:29888759. |
aversion or salience signaling by ventral tegmental area glutamate neurons. |
2021-01-09 |
2023-08-13 |
Not clear |
| David H Root, David J Estrin, Marisela Morale. Aversion or Salience Signaling by Ventral Tegmental Area Glutamate Neurons. iScience. vol 2. 2021-01-09. PMID:29888759. |
ventral tegmental area (vta) neurons play roles in reward and aversion. |
2021-01-09 |
2023-08-13 |
Not clear |
| M Flavia Barbano, Hui-Ling Wang, Shiliang Zhang, Jorge Miranda-Barrientos, David J Estrin, Almaris Figueroa-González, Bing Liu, David J Barker, Marisela Morale. VTA Glutamatergic Neurons Mediate Innate Defensive Behaviors. Neuron. vol 107. issue 2. 2020-10-19. PMID:32442399. |
the ventral tegmental area (vta) has dopamine, gaba, and glutamate neurons, which have been implicated in reward and aversion. |
2020-10-19 |
2023-08-13 |
Not clear |
| Ozra Dehkordi, Jed E Rose, Richard M Millis, Maryam Mehdipour Dalivand, Shereé M Johnso. GABAergic Neurons as Putative Neurochemical Substrate Mediating Aversive Effects of Nicotine. Journal of alcoholism and drug dependence. vol 6. issue 2. 2020-10-01. PMID:30009210. |
in the present study of transgenic mice expressing green fluorescent protein (gfp) in glutamate decarboxylase 67 (gad67) neurons, we hypothesized that a subpopulation of gabaergic neurons in the ventral tegmental area (vta) are the targets of aversive doses of nicotine in the cns. |
2020-10-01 |
2023-08-13 |
mouse |
| Geiza Fernanda Antunes, Flavia Venetucci Gouveia, Fabiana Strambio Rezende, Midiã Dias de Jesus Seno, Milene Cristina de Carvalho, Caroline Cruz de Oliveira, Lennon Cardoso Tosati Dos Santos, Marina Correia de Castro, Mayra Akemi Kuroki, Manoel Jacobsen Teixeira, José Pinhata Otoch, Marcus Lira Brandao, Erich Talamoni Fonoff, Raquel Chacon Ruiz Martine. Dopamine modulates individual differences in avoidance behavior: A pharmacological, immunohistochemical, neurochemical and volumetric investigation. Neurobiology of stress. vol 12. 2020-09-28. PMID:32435668. |
additionally, the good performers had lower levels of dopac and hva in the amygdala, an increase in the total volume of the amygdala (amg), substantia nigra (sn), ventral tegmental area (vta) and locus coeruleus (lc), and an increase in the number of tyrosine hydroxylase-positive cells in sn, vta and lc, which positively correlates with the avoidance behavior. |
2020-09-28 |
2023-08-13 |
Not clear |