| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jfw Deaki. The origins of '5-HT and mechanisms of defence' by Deakin and Graeff: a personal perspective. Journal of psychopharmacology (Oxford, England). vol 27. issue 12. 2015-01-27. PMID:24067790. |
the principal insight was that different 5-ht pathways mediate distinct adaptive responses to aversive events of different types. |
2015-01-27 |
2023-08-12 |
human |
| Jfw Deaki. The origins of '5-HT and mechanisms of defence' by Deakin and Graeff: a personal perspective. Journal of psychopharmacology (Oxford, England). vol 27. issue 12. 2015-01-27. PMID:24067790. |
it emerged from a number of strands in neuropsychopharmacology: the functional implications of the still-fresh images of monoamine neuroanatomy of the 1970s; the ethological differentiation of behavioural responses to proximal and distal threats; and the seemingly contradictory effects of 5-ht drugs in unconditioned, pavlovian and instrumental paradigms of reward and aversion. |
2015-01-27 |
2023-08-12 |
human |
| Maria Adrielle Vicente, Helio Zangross. Serotonin-2C receptors in the basolateral nucleus of the amygdala mediate the anxiogenic effect of acute imipramine and fluoxetine administration. The international journal of neuropsychopharmacology. vol 15. issue 3. 2015-01-22. PMID:21733232. |
while intra-bla administration of 5-ht and mk-212 facilitated inhibitory avoidance acquisition, suggesting an anxiogenic effect, sb-242084 had the opposite effect. |
2015-01-22 |
2023-08-12 |
rat |
| Julian Macovean. Serotonergic modulation of reward and punishment: evidence from pharmacological fMRI studies. Brain research. vol 1556. 2014-11-06. PMID:24508910. |
the reviewed research has revealed how central serotonin availability and receptor specific transmission modulates the neural response to both appetitive (rewarding) and aversive (punishing) stimuli in putative reward-related brain regions. |
2014-11-06 |
2023-08-12 |
human |
| A B Klein, L Ultved, D Adamsen, M A Santini, A Tobeña, A Fernandez-Teruel, P Flores, M Moreno, D Cardona, G M Knudsen, S Aznar, J D Mikkelse. 5-HT(2A) and mGlu2 receptor binding levels are related to differences in impulsive behavior in the Roman Low- (RLA) and High- (RHA) avoidance rat strains. Neuroscience. vol 263. 2014-10-31. PMID:24412375. |
5-ht(2a) and mglu2 receptor binding levels are related to differences in impulsive behavior in the roman low- (rla) and high- (rha) avoidance rat strains. |
2014-10-31 |
2023-08-12 |
rat |
| Pascal Fossat, Julien Bacqué-Cazenave, Philippe De Deurwaerdère, Jean-Paul Delbecque, Daniel Cattaer. Comparative behavior. Anxiety-like behavior in crayfish is controlled by serotonin. Science (New York, N.Y.). vol 344. issue 6189. 2014-06-23. PMID:24926022. |
serotonin injection into unstressed crayfish induced avoidance; again, this effect was reversed by injection with chlordiazepoxide. |
2014-06-23 |
2023-08-13 |
Not clear |
| Joel Weinberger, Rebecca Klape. Environmental concentrations of the selective serotonin reuptake inhibitor fluoxetine impact specific behaviors involved in reproduction, feeding and predator avoidance in the fish Pimephales promelas (fathead minnow). Aquatic toxicology (Amsterdam, Netherlands). vol 151. 2014-05-22. PMID:24210950. |
environmental concentrations of the selective serotonin reuptake inhibitor fluoxetine impact specific behaviors involved in reproduction, feeding and predator avoidance in the fish pimephales promelas (fathead minnow). |
2014-05-22 |
2023-08-12 |
Not clear |
| Derrik E Asher, Alexis B Craig, Andrew Zaldivar, Alyssa A Brewer, Jeffrey L Krichma. A dynamic, embodied paradigm to investigate the role of serotonin in decision-making. Frontiers in integrative neuroscience. vol 7. 2014-04-22. PMID:24319413. |
serotonin (5-ht) is a neuromodulator that has been attributed to cost assessment and harm aversion. |
2014-04-22 |
2023-08-12 |
human |
| Ursula F Bailer, Guido K Frank, Julie C Price, Carolyn C Meltzer, Carl Becker, Chester A Mathis, Angela Wagner, Nicole C Barbarich-Marsteller, Cinnamon S Bloss, Karen Putnam, Nicholas J Schork, Anthony Gamst, Walter H Kay. Interaction between serotonin transporter and dopamine D2/D3 receptor radioligand measures is associated with harm avoidant symptoms in anorexia and bulimia nervosa. Psychiatry research. vol 211. issue 2. 2014-04-21. PMID:23154100. |
based on theories that 5-ht is an aversive motivational system that may oppose a da-related appetitive system, we explored interactions of positron emission tomography (pet) radioligand measures that reflect portions of these systems. |
2014-04-21 |
2023-08-12 |
Not clear |
| Iu O Fedotova, N S Saprono. [Co-administration of NAN-190 with low dose of testosterone propionate improves passive avoidance performance in rats with androgen deficiency]. Eksperimental'naia i klinicheskaia farmakologiia. vol 76. issue 12. 2014-04-07. PMID:24605422. |
we have studied the effect of stimulation or blockade of the 5-ht(1a) receptors on the passive avoidance performance and open-field test behavior in gonadectomized (gdx) male rats of middle age treated with a low dose of testosterone propionate. |
2014-04-07 |
2023-08-12 |
rat |
| Hiroki Shikanai, Shinichi Kimura, Hiroko Togash. Early life stress affects the serotonergic system underlying emotional regulation. Biological & pharmaceutical bulletin. vol 36. issue 9. 2014-04-01. PMID:23995647. |
an aversive stimulus, foot shock (fs), during the early postnatal period (2-3 weeks after birth) produced behavioral, neuroanatomical and electrophysiological changes accompanied by serotonergic dysfunction, especially functional impairment of the serotonin (5-hydroxytryptamine; 5-ht)1a receptor in the cortico-limbic area. |
2014-04-01 |
2023-08-12 |
rat |
| Julian Macoveanu, James B Rowe, Bettina Hornboll, Rebecca Elliott, Olaf B Paulson, Gitte M Knudsen, Hartwig R Siebne. Playing it safe but losing anyway--serotonergic signaling of negative outcomes in dorsomedial prefrontal cortex in the context of risk-aversion. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 8. 2014-03-13. PMID:23051938. |
however, it is unclear whether serotonin provides a neurobiological link between making a risk aversive decision and the response to a negative outcome. |
2014-03-13 |
2023-08-12 |
human |
| V P Nikitin, S V Solntsev. Peculiarities of amnesia development during memory reconsolidation impairment induced by isolated or combined treatment with neurotransmitter receptor antagonists. Bulletin of experimental biology and medicine. vol 155. issue 1. 2014-02-21. PMID:23667859. |
the effects of serotonin and glutamate receptor antagonists on conditioned food aversion memory reconsolidation were studied in experiments on edible snails. |
2014-02-21 |
2023-08-12 |
Not clear |
| N P Shugalev, A V Stavrovskaia, N G Iamshchikova, A S Ol'shanskiĭ, E A Kashirin. [Neurotensin influence on painful stress afteractions in rats with neurotoxic damages of serotoninergic structures of brain substantia nigra]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 63. issue 3. 2014-02-21. PMID:24450170. |
the prevention of this effect development after neurotensin administrations into caudate nucleus may be specified by recovery of recall passive avoidance reactions destroyed by neurotoxin action and is explained by normalization of relationships balance of 5-ht and dopaminergic brain systems. |
2014-02-21 |
2023-08-12 |
rat |
| Lukasz Piszczek, Kevin Schlax, Anna Wyrzykowska, Agnieszka Piszczek, Enrica Audero, Cornelius Thilo Gros. Serotonin 1A auto-receptors are not sufficient to modulate anxiety in mice. The European journal of neuroscience. vol 38. issue 4. 2014-02-19. PMID:23701504. |
mice lacking the serotonin 1a receptor (htr1a) show elevated avoidance of novel open spaces, suggesting that it has a role in modulating anxiety behavior. |
2014-02-19 |
2023-08-12 |
mouse |
| Dirk E M Geurts, Quentin J M Huys, Hanneke E M den Ouden, Roshan Cool. Serotonin and aversive Pavlovian control of instrumental behavior in humans. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 48. 2014-01-28. PMID:24285898. |
serotonin and aversive pavlovian control of instrumental behavior in humans. |
2014-01-28 |
2023-08-12 |
Not clear |
| Dirk E M Geurts, Quentin J M Huys, Hanneke E M den Ouden, Roshan Cool. Serotonin and aversive Pavlovian control of instrumental behavior in humans. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 48. 2014-01-28. PMID:24285898. |
here we investigate in humans the role of serotonin in such pavlovian-instrumental transfer in both the aversive and the appetitive domain using acute tryptophan depletion, known to lower central serotonin levels. |
2014-01-28 |
2023-08-12 |
Not clear |
| Dirk E M Geurts, Quentin J M Huys, Hanneke E M den Ouden, Roshan Cool. Serotonin and aversive Pavlovian control of instrumental behavior in humans. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 48. 2014-01-28. PMID:24285898. |
these data suggest that serotonin is selectively involved in pavlovian inhibition due to aversive expectations and have implications for our understanding of the mechanisms underlying a range of affective, impulsive, and aggressive neuropsychiatric disorders. |
2014-01-28 |
2023-08-12 |
Not clear |
| Cheryl L Grady, Hartwig R Siebner, Bettina Hornboll, Julian Macoveanu, Olaf B Paulson, Gitte M Knudse. Acute pharmacologically induced shifts in serotonin availability abolish emotion-selective responses to negative face emotions in distinct brain networks. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 5. 2013-12-27. PMID:22739125. |
using a within-subject design, we measured the effect of serotonin on the brain's response to aversive face emotions with functional mri while 20 participants judged the gender of neutral, fearful and angry faces. |
2013-12-27 |
2023-08-12 |
human |
| Cheryl L Grady, Hartwig R Siebner, Bettina Hornboll, Julian Macoveanu, Olaf B Paulson, Gitte M Knudse. Acute pharmacologically induced shifts in serotonin availability abolish emotion-selective responses to negative face emotions in distinct brain networks. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 5. 2013-12-27. PMID:22739125. |
lower serotonin leads to a broadening of a normally fear-specific response to anger, and higher levels reduce the differentiated brain response to aversive face emotions. |
2013-12-27 |
2023-08-12 |
human |