| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anand B Pithadia, Sunita M Jai. 5-Hydroxytryptamine Receptor Subtypes and their Modulators with Therapeutic Potentials. Journal of clinical medicine research. vol 1. issue 2. 2012-08-23. PMID:22505971. |
discovery of 5-ht, its biosynthesis, metabolism, physiological role and the potential of 5-ht receptor modulators in various nervous, cardiovascular and gastrointestinal tract disorders, bone growth and micturition have been discussed in this article. |
2012-08-23 |
2023-08-12 |
Not clear |
| George K Papadimas, Konstantinos N Tzirogiannis, Michael G Mykoniatis, Agni D Grypioti, Georgia A Manta, Georgios I Panoutsopoulo. The emerging role of serotonin in liver regeneration. Swiss medical weekly. vol 142. 2012-08-20. PMID:22495635. |
there is a growing body of evidence implicating serotonin in hepatic regeneration through altered expression of serotonin receptor subtypes in the liver. |
2012-08-20 |
2023-08-12 |
Not clear |
| W P Clarke, K A Berg, G Gould, A Fraze. Characterization of 5-HT(₁A,B) and 5-HT(₂A,C) serotonin receptor binding. Current protocols in pharmacology. vol Chapter 1. 2012-08-03. PMID:21959751. |
characterization of 5-ht(₁a,b) and 5-ht(₂a,c) serotonin receptor binding. |
2012-08-03 |
2023-08-12 |
rat |
| Stephane Besnard, Hanan Khemiri, Fabienne Masse, Pierre Denise, Marion Verdaguer, Christian Gestrea. Differential respiratory control of the upper airway and diaphragm muscles induced by 5-HT1A receptor ligands. Sleep & breathing = Schlaf & Atmung. vol 16. issue 1. 2012-07-24. PMID:21221824. |
although 5-ht affects respiratory drive to both phrenic and cranial motoneurons, relatively little is known about the role of 5-ht receptor subtypes in the control of upper airway muscle (uam) respiratory activity. |
2012-07-24 |
2023-08-12 |
Not clear |
| L Costa, C Trovato, S A Musumeci, M V Catania, L Cirann. 5-HT(1A) and 5-HT(7) receptors differently modulate AMPA receptor-mediated hippocampal synaptic transmission. Hippocampus. vol 22. issue 4. 2012-07-24. PMID:21538661. |
we have studied the effects of 5-ht(1a) and 5-ht(7) serotonin receptor activation in hippocampal ca3-ca1 synaptic transmission using patch clamp on mouse brain slices. |
2012-07-24 |
2023-08-12 |
mouse |
| Richard T O'Neil, Ronald B Emeso. Quantitative analysis of 5HT(2C) receptor RNA editing patterns in psychiatric disorders. Neurobiology of disease. vol 45. issue 1. 2012-07-23. PMID:21914481. |
here, we focus on the editing of transcripts encoding the 2c-subtype of serotonin receptor (5ht(2c)) to generate multiple receptor isoforms that differ in g-protein coupling efficacy and constitutive activity. |
2012-07-23 |
2023-08-12 |
human |
| L Kahsai, M A Carlsson, A M E Winther, D R Nässe. Distribution of metabotropic receptors of serotonin, dopamine, GABA, glutamate, and short neuropeptide F in the central complex of Drosophila. Neuroscience. vol 208. 2012-07-20. PMID:22361394. |
by combining immunocytochemistry with gal4 driven green fluorescent protein, we examined the distribution patterns of six different gpcrs: two serotonin receptor subtypes (5-ht(1b) and 5-ht(7)), a dopamine receptor (dopr), the metabotropic gaba(b) receptor (gaba(b)r), the metabotropic glutamate receptor (dmglur(a)) and a short neuropeptide f receptor (snpfr1). |
2012-07-20 |
2023-08-12 |
drosophila_melanogaster |
| Stephanie W Watts, Shaun F Morrison, Robert Patrick Davis, Susan M Barma. Serotonin and blood pressure regulation. Pharmacological reviews. vol 64. issue 2. 2012-07-16. PMID:22407614. |
we compare the change in blood pressure produced in different species by short- and long-term administration of 5-ht or selective serotonin receptor agonists. |
2012-07-16 |
2023-08-12 |
Not clear |
| David F Moffett, Urmila Jagadeshwaran, Zeping Wang, Hana M Davis, Horst Onken, Greg G Gos. Signaling by intracellular Ca2+ and H+ in larval mosquito (Aedes aegypti) midgut epithelium in response to serosal serotonin and lumen pH. Journal of insect physiology. vol 58. issue 4. 2012-07-10. PMID:22172381. |
quantitative real-time rt-pcr revealed expression of 5 putative 5-ht receptor types in amg, including 5-ht(2)-like receptors which would be expected to initiate a ca(2+) signal. |
2012-07-10 |
2023-08-12 |
Not clear |
| Adam L Halberstadt, Liselore Koedood, Susan B Powell, Mark A Geye. Differential contributions of serotonin receptors to the behavioral effects of indoleamine hallucinogens in mice. Journal of psychopharmacology (Oxford, England). vol 25. issue 11. 2012-06-27. PMID:21148021. |
we also compared the effects of psilocin with those of the putative 5-ht(2c) receptor-selective agonist 1-methylpsilocin and the hallucinogen and non-selective serotonin receptor agonist 5-methoxy-n,n-dimethyltryptamine (5-meo-dmt). |
2012-06-27 |
2023-08-12 |
mouse |
| Hiroyuki Yoshida, Chisako Kanamaru, Akiko Ohtani, Fei Li, Kouji Senzaki, Takashi Shig. Subtype specific roles of serotonin receptors in the spine formation of cortical neurons in vitro. Neuroscience research. vol 71. issue 3. 2012-06-25. PMID:21802453. |
embryonic rat cortical neurons were cultured for 10 or 14 days and treated by 5-ht receptor agonists for 24 h. at 11 days in vitro, 5-ht(1a) agonist increased filopodia density, whereas 5-ht(2a/2c) agonist increased the density of puncta and spines. |
2012-06-25 |
2023-08-12 |
rat |
| Grietje Krabbe, Vitali Matyash, Ulrike Pannasch, Lauren Mamer, Hendrikus W G M Boddeke, Helmut Kettenman. Activation of serotonin receptors promotes microglial injury-induced motility but attenuates phagocytic activity. Brain, behavior, and immunity. vol 26. issue 3. 2012-06-22. PMID:22198120. |
in this project we studied the impact of serotonin receptor activation on distinct microglial properties as serotonin deficiency not only has been linked to a number of psychiatric disease like depression and anxiety but may also permeate from the periphery through blood-brain barrier openings seen in neurodegenerative disease. |
2012-06-22 |
2023-08-12 |
mouse |
| G J Moldering. Physiological, pathophysiological and therapeutic impact of the enteric serotonergic system. Arzneimittel-Forschung. vol 62. issue 4. 2012-06-18. PMID:22438071. |
in the light of the current knowledge about the anatomy and physiology of the serotonergic system and the distribution of the various 5-ht receptors in the gut, the established and potential therapeutic impact of 5-ht receptor ligands are discussed. |
2012-06-18 |
2023-08-12 |
Not clear |
| Anne Matthys, Kathleen Van Craenenbroeck, Béatrice Lintermans, Guy Haegeman, Peter Vanhoenacke. RhoBTB3 interacts with the 5-HT7a receptor and inhibits its proteasomal degradation. Cellular signalling. vol 24. issue 5. 2012-06-06. PMID:22245496. |
the 5-hydroxytryptamine (5-ht)7 receptor is the most recently identified serotonin receptor and is involved in a wide variety of central nervous system (cns) functions, namely circadian rhythm, rem sleep, depression, thermoregulation, obsessive-compulsive disorder (ocd), anxiety, schizophrenia, epilepsy, nociception, migraine, sensation-seeking behavior, impulsivity, learning and memory. |
2012-06-06 |
2023-08-12 |
Not clear |
| Y Xu, C Zhang, R Wang, S S Govindarajan, P A Barish, M M Vernon, C Fu, A P Acharya, L Chen, E Boykin, J Yu, J Pan, J M O'Donnell, W O Ogl. Corticosterone induced morphological changes of hippocampal and amygdaloid cell lines are dependent on 5-HT7 receptor related signal pathway. Neuroscience. vol 182. 2012-05-31. PMID:21371532. |
these observed results support the hypothesis that 5-ht may differentially modulate neuronal morphology in the hippocampus and amygdala depending on the expression levels of the 5-ht receptor subtypes during stress hormone insults. |
2012-05-31 |
2023-08-12 |
Not clear |
| Bruno Campos, Benjamín Piña, Carlos Barata . Mechanisms of action of selective serotonin reuptake inhibitors in Daphnia magna. Environmental science & technology. vol 46. issue 5. 2012-05-29. PMID:22324381. |
d. magna reproduction tests, respiration, feeding, and survival-starvation assays and studies of lipids, proteins, and carbohydrate levels of unexposed and exposed females to the ssri fluoxetine and fluvoxamine and the 5-ht serotonin receptor antagonist cyproheptadine were conducted. |
2012-05-29 |
2023-08-12 |
Not clear |
| Ashley N Hutchinson, Jie V Deng, Dipendra K Aryal, William C Wetsel, Anne E Wes. Differential regulation of MeCP2 phosphorylation in the CNS by dopamine and serotonin. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 2. 2012-04-17. PMID:21956448. |
administration of selective da and 5-ht receptor agonists was also sufficient to induce pmecp2; however, the specific combination of da and 5-ht receptors activated determined the regional- and cell-type specificity of pmecp2 induction. |
2012-04-17 |
2023-08-12 |
mouse |
| Katherine W Figueroa, Graeme R Martin, M Teresa Pulido-Rio. 5-Hydroxytryptamine receptor assays. Current protocols in pharmacology. vol Chapter 4. 2012-04-02. PMID:22294394. |
the tissue-specific distribution of these receptors confers specificity for the actions of serotonin and highlights the therapeutic potential of serotonin receptor modulators. |
2012-04-02 |
2023-08-12 |
rat |
| Katherine C Murray, Marilee J Stephens, Michelle Rank, Jessica D'Amico, Monica A Gorassini, David J Bennet. Polysynaptic excitatory postsynaptic potentials that trigger spasms after spinal cord injury in rats are inhibited by 5-HT1B and 5-HT1F receptors. Journal of neurophysiology. vol 106. issue 2. 2012-03-26. PMID:21653728. |
the potencies of 5-ht receptor agonists were highly correlated with their binding affinity to 5-ht(1b) and 5-ht(1f) receptors, and not to other 5-ht receptors. |
2012-03-26 |
2023-08-12 |
rat |
| Marta Gajdus, Leszek Szadujkis-Szadurski, Rafał Szadujkis-Szadurski, Izabela Glaza, Magdalena Zalewska, Katarzyna Szadujkis-Szadurska, Natalia Gurtowsk. Role of calcium and calmodulin in reaction of gastric fundus contraction. Postepy higieny i medycyny doswiadczalnej (Online). vol 65. 2012-03-01. PMID:21918260. |
during experiments, the author tested the influence of a serotonin receptor agonist, serotonin (5-ht), causing smooth muscle contraction. |
2012-03-01 |
2023-08-12 |
human |