| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kim van Rooij, Saskia Poels, Jos Bloemers, Irwin Goldstein, Jeroen Gerritsen, Diana van Ham, Frederiek van Mameren, Meredith Chivers, Walter Everaerd, Hans Koppeschaar, Berend Olivier, Adriaan Tuite. Toward personalized sexual medicine (part 3): testosterone combined with a Serotonin1A receptor agonist increases sexual satisfaction in women with HSDD and FSAD, and dysfunctional activation of sexual inhibitory mechanisms. The journal of sexual medicine. vol 10. issue 3. 2013-09-19. PMID:23130675. |
a single dose of 5-ht receptor agonist (5-ht(1a)ra) might reduce the sexual stimulation induced pfc-mediated sexual inhibition during a short period after administration. |
2013-09-19 |
2023-08-12 |
Not clear |
| Ephraim F Trakhtenberg, Jeffrey L Goldber. The role of serotonin in axon and dendrite growth. International review of neurobiology. vol 106. 2013-09-19. PMID:23211461. |
5-ht predominantly appears to suppress neurite growth, but depending on the model system and 5-ht receptor subtype, in rare cases, it may promote neurite outgrowth and elongation. |
2013-09-19 |
2023-08-12 |
Not clear |
| Yoshihiro Gocho, Atsushi Sakai, Yuchio Yanagawa, Hidenori Suzuki, Fumihito Saito. Electrophysiological and pharmacological properties of GABAergic cells in the dorsal raphe nucleus. The journal of physiological sciences : JPS. vol 63. issue 2. 2013-08-12. PMID:23275149. |
these results suggested that multiple 5-ht receptor subtypes overlap on gabaergic cells, and their combination might control 5-ht cells. |
2013-08-12 |
2023-08-12 |
mouse |
| Kumud Raj Poudel, Jeffrey P Jones, James A Brozi. A guide to tracking single transmembrane proteins in supported lipid bilayers. Methods in molecular biology (Clifton, N.J.). vol 974. 2013-08-06. PMID:23404279. |
the procedure for the detergent-mediated incorporation of the transmembrane protein 5ht(3a) (a serotonin receptor) is also described and can be used as a starting point for other large non-self-inserting transmembrane proteins. |
2013-08-06 |
2023-08-12 |
Not clear |
| Janice J Kim, Byram W Bridle, Jean-Eric Ghia, Huaqing Wang, Shahzad N Syed, Marcus M Manocha, Palanivel Rengasamy, Mohammad Sharif Shajib, Yonghong Wan, Peter B Hedlund, Waliul I Kha. Targeted inhibition of serotonin type 7 (5-HT7) receptor function modulates immune responses and reduces the severity of intestinal inflammation. Journal of immunology (Baltimore, Md. : 1950). vol 190. issue 9. 2013-07-29. PMID:23554310. |
5-ht type 7 (5-ht7) receptor is one of the most recently identified members of the 5-ht receptor family, and dendritic cells express this receptor. |
2013-07-29 |
2023-08-12 |
mouse |
| T B Kalinnikova, R R Kolsanova, R R Shagidullin, E B Osipova, M Kh Gaĭnutdino. [On the role of gene of SER-4 serotonin receptor in thermotolerance of Caenorhabditis elegans behavior]. Genetika. vol 49. issue 3. 2013-07-15. PMID:23755541. |
serotonin reduces the behavior tolerance of caenorhabditis elegans of the n2 wild-type strain (swimming induced by the mechanical stimulus) to a temperature of 36 degrees c. the sensitivity to the serotonin influence on the behavior thermotolerance remains intact in strains with null mutations of mod-1 (ok103) and ser-1 (ok345) serotonin receptor genes, and is almost completely lost in the ser-4 (ok512) strain with null mutation in the gene of the ser-4 serotonin receptor, which is a homologue of 5-ht1 mammalian serotonin receptor. |
2013-07-15 |
2023-08-12 |
caenorhabditis_elegans |
| Stefanie C Altieri, Alvaro L Garcia-Garcia, E David Leonardo, Anne M Andrew. Rethinking 5-HT1A receptors: emerging modes of inhibitory feedback of relevance to emotion-related behavior. ACS chemical neuroscience. vol 4. issue 1. 2013-07-02. PMID:23336046. |
the complexities of the involvement of the serotonin transmitter system in numerous biological processes and psychiatric disorders is, to a substantial degree, attributable to the large number of serotonin receptor families and subtypes that have been identified and characterized for over four decades. |
2013-07-02 |
2023-08-12 |
Not clear |
| Susanna Ly, Bano Pishdari, Ling Ling Lok, Mihaly Hajos, Bernat Kocsi. Activation of 5-HT6 receptors modulates sleep-wake activity and hippocampal theta oscillation. ACS chemical neuroscience. vol 4. issue 1. 2013-07-02. PMID:23336058. |
the modulatory role of 5-ht neurons and a number of different 5-ht receptor subtypes has been well documented in the regulation of sleep-wake cycles and hippocampal activity. |
2013-07-02 |
2023-08-12 |
rat |
| Claudia Röser, Nadine Jordan, Sabine Balfanz, Arnd Baumann, Bernd Walz, Otto Baumann, Wolfgang Blena. Molecular and pharmacological characterization of serotonin 5-HT2α and 5-HT7 receptors in the salivary glands of the blowfly Calliphora vicina. PloS one. vol 7. issue 11. 2013-06-25. PMID:23145175. |
we observed that 5-methoxytryptamine (100 nm) activates only the cv5-ht(2α) receptor, 5-carboxamidotryptamine (300 nm) activates only the cv5-ht(7) receptor, and clozapine (1 µm) antagonizes the effects of 5-ht via cv5-ht(7) in blowfly salivary glands, providing means for the selective activation of each of the two 5-ht receptor subtypes. |
2013-06-25 |
2023-08-12 |
Not clear |
| Christie L Burton, Zoë Rizos, Mustansir Diwan, José N Nobrega, Paul J Fletche. Antagonizing 5-HT₂A receptors with M100907 and stimulating 5-HT₂C receptors with Ro60-0175 blocks cocaine-induced locomotion and zif268 mRNA expression in Sprague-Dawley rats. Behavioural brain research. vol 240. 2013-06-17. PMID:23201361. |
the direction of this modulation depends upon the 5-ht receptor subtypes involved, with 5-ht(2a) and 5-ht(2c) receptors having opposing effects. |
2013-06-17 |
2023-08-12 |
rat |
| Melina Ellis, Jordan D Chambers, Rachel M Gwynne, Joel C Bornstei. Serotonin and cholecystokinin mediate nutrient-induced segmentation in guinea pig small intestine. American journal of physiology. Gastrointestinal and liver physiology. vol 304. issue 8. 2013-06-17. PMID:23392236. |
segmenting activity mediated by decanoic acid was depressed following luminal application of the 5-ht receptor antagonists granisetron (5-ht(3), 1 μm) and sb-207266 (5-ht(4), 10 nm) and the cck receptor antagonists devazepide (cck-1, 300 nm) and l-365260 (cck-2, 300 nm), but these antagonists did not further depress segmentation when combined. |
2013-06-17 |
2023-08-12 |
Not clear |
| David R Maguire, Jun-Xu Li, Wouter Koek, Charles P Franc. Effects of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane (DOM) and quipazine on heroin self-administration in rhesus monkeys. Psychopharmacology. vol 225. issue 1. 2013-06-10. PMID:22836370. |
the serotonin (5-ht) system is involved in pain modulation, and 5-ht receptor agonists can enhance antinociceptive effects of mu opioid receptor agonists. |
2013-06-10 |
2023-08-12 |
monkey |
| Lea R Medeiros, M Danielle McDonal. Elevated cortisol inhibits adrenocorticotropic hormone- and serotonin-stimulated cortisol secretion from the interrenal cells of the Gulf toadfish (Opsanus beta). General and comparative endocrinology. vol 179. issue 3. 2013-06-07. PMID:23022993. |
to test these hypotheses, interrenal cells from uncrowded, crowded, vehicle-, and cortisol-implanted toadfish were incubated with either acth, 5-ht or 5-ht receptor agonists, and cortisol secretion was measured. |
2013-06-07 |
2023-08-12 |
Not clear |
| Chong Wang, Yi Jiang, Jinming Ma, Huixian Wu, Daniel Wacker, Vsevolod Katritch, Gye Won Han, Wei Liu, Xi-Ping Huang, Eyal Vardy, John D McCorvy, Xiang Gao, X Edward Zhou, Karsten Melcher, Chenghai Zhang, Fang Bai, Huaiyu Yang, Linlin Yang, Hualiang Jiang, Bryan L Roth, Vadim Cherezov, Raymond C Stevens, H Eric X. Structural basis for molecular recognition at serotonin receptors. Science (New York, N.Y.). vol 340. issue 6132. 2013-05-21. PMID:23519210. |
serotonin or 5-hydroxytryptamine (5-ht) regulates a wide spectrum of human physiology through the 5-ht receptor family. |
2013-05-21 |
2023-08-12 |
human |
| Chong Wang, Yi Jiang, Jinming Ma, Huixian Wu, Daniel Wacker, Vsevolod Katritch, Gye Won Han, Wei Liu, Xi-Ping Huang, Eyal Vardy, John D McCorvy, Xiang Gao, X Edward Zhou, Karsten Melcher, Chenghai Zhang, Fang Bai, Huaiyu Yang, Linlin Yang, Hualiang Jiang, Bryan L Roth, Vadim Cherezov, Raymond C Stevens, H Eric X. Structural basis for molecular recognition at serotonin receptors. Science (New York, N.Y.). vol 340. issue 6132. 2013-05-21. PMID:23519210. |
the orthosteric pocket is formed by residues conserved in the 5-ht receptor family, clarifying the family-wide agonist activity of 5-ht. |
2013-05-21 |
2023-08-12 |
human |
| Hu Zhu, Daniel J Urban, Jared Blashka, Matthew T McPheeters, Wesley K Kroeze, Piotr Mieczkowski, James C Overholser, George J Jurjus, Lesa Dieter, Gouri J Mahajan, Grazyna Rajkowska, Zefeng Wang, Patrick F Sullivan, Craig A Stockmeier, Bryan L Rot. Quantitative analysis of focused a-to-I RNA editing sites by ultra-high-throughput sequencing in psychiatric disorders. PloS one. vol 7. issue 8. 2013-05-01. PMID:22912834. |
in striking contrast to many prior studies, we did not find significant alterations in the frequency of rna editing at any of the editing sites in samples from these patients, including within the 5ht(2c) serotonin receptor (htr2c). |
2013-05-01 |
2023-08-12 |
human |
| Amine Benyamina, Mickaël Naassila, Michel Bouri. Potential role of cortical 5-HT(2A) receptors in the anxiolytic action of cyamemazine in benzodiazepine withdrawal. Psychiatry research. vol 198. issue 2. 2013-04-23. PMID:22421069. |
the 5-ht(2ar) is the most abundant serotonin receptor subtype in the cortex. |
2013-04-23 |
2023-08-12 |
mouse |
| R Hazra, J D Guo, J Dabrowska, D G Rainni. Differential distribution of serotonin receptor subtypes in BNST(ALG) neurons: modulation by unpredictable shock stress. Neuroscience. vol 225. 2013-04-16. PMID:22922122. |
type ii neurons expressed transcripts for every 5-ht receptor except the 5-ht(2c) receptor. |
2013-04-16 |
2023-08-12 |
Not clear |
| Alexander Sturzu, Sumbla Sheikh, Uwe Klose, Hartmut Echner, Hubert Kalbacher, Martin Deeg, Thomas Nägele, Marius Horger, Ulrike Ernemann, Stefan Heck. Using the neurotransmitter serotonin to target imaging agents to glioblastoma cells. Investigational new drugs. vol 30. issue 6. 2013-04-04. PMID:22212740. |
the neurotransmitter serotonin is involved in numerous bodily functions via seven different serotonin receptor subfamilies. |
2013-04-04 |
2023-08-12 |
human |
| O Riccio, M Jacobshagen, B Golding, L Vutskits, D Jabaudon, J P Hornung, A G Daye. Excess of serotonin affects neocortical pyramidal neuron migration. Translational psychiatry. vol 1. 2013-04-04. PMID:22833193. |
we further identify that the serotonin receptor 5-ht(6) is expressed in pyramidal neuron progenitors and that 5-ht(6) receptor activation replicates the effects of serotonin stimulation. |
2013-04-04 |
2023-08-12 |
mouse |