| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| María Eugenia Cornide-Petronio, Ramón Anadón, Antón Barreiro-Iglesias, María Celina Rodici. Serotonin 1A receptor (5-HT1A) of the sea lamprey: cDNA cloning and expression in the central nervous system. Brain structure & function. vol 218. issue 5. 2014-03-10. PMID:23052550. |
one of the major targets of the activity of serotonergic cells is the serotonin 1a receptor (5-ht1a), an ancestral archetypical serotonin receptor. |
2014-03-10 |
2023-08-12 |
Not clear |
| Elodie Bouaziz, Michel Boris Emerit, Guilan Vodjdani, Vanessa Gautheron, Michel Hamon, Michèle Darmon, Justine Masso. Neuronal phenotype dependency of agonist-induced internalization of the 5-HT(1A) serotonin receptor. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 1. 2014-02-24. PMID:24381289. |
neuronal phenotype dependency of agonist-induced internalization of the 5-ht(1a) serotonin receptor. |
2014-02-24 |
2023-08-12 |
rat |
| Balaji Selvam, Simon L Porter, Irina G Tikhonov. Addressing selective polypharmacology of antipsychotic drugs targeting the bioaminergic receptors through receptor dynamic conformational ensembles. Journal of chemical information and modeling. vol 53. issue 7. 2014-02-20. PMID:23789628. |
among them, it has been shown that the serotonin (5-ht(2a) and 5-ht₆) and dopamine (d₂ and d₃) receptors induce a cognition-enhancing effect (group 1), while the histamine (h₁) and serotonin (5-ht(2c)) receptors lead to metabolic side effects and the 5-ht(2b) serotonin receptor causes pulmonary hypertension (group 2). |
2014-02-20 |
2023-08-12 |
Not clear |
| Benedetta Assetta, Melissa S Maginnis, Irene Gracia Ahufinger, Sheila A Haley, Gretchen V Gee, Christian D S Nelson, Bethany A O'Hara, Stacy-ann A Allen Ramdial, Walter J Atwoo. 5-HT2 receptors facilitate JC polyomavirus entry. Journal of virology. vol 87. issue 24. 2014-02-05. PMID:24089568. |
jcpyv infection of host cells requires the pentasaccharide lactoseries tetrasaccharide c (lstc) and the serotonin receptor 5-hydroxytryptamine (5-ht) receptor 5-ht2ar. |
2014-02-05 |
2023-08-12 |
human |
| Benedetta Assetta, Melissa S Maginnis, Irene Gracia Ahufinger, Sheila A Haley, Gretchen V Gee, Christian D S Nelson, Bethany A O'Hara, Stacy-ann A Allen Ramdial, Walter J Atwoo. 5-HT2 receptors facilitate JC polyomavirus entry. Journal of virology. vol 87. issue 24. 2014-02-05. PMID:24089568. |
to further define the roles of serotonin receptors in infection, hek293a cells, which are poorly permissive to jcpyv, were transfected with 14 different isoforms of serotonin receptor. |
2014-02-05 |
2023-08-12 |
human |
| Yinghua Yu, Yizhen Wu, Craig Patch, Zhixiang Wu, Alexander Szabo, Duo Li, Xu-Feng Huan. DHA prevents altered 5-HT1A, 5-HT2A, CB1 and GABAA receptor binding densities in the brain of male rats fed a high-saturated-fat diet. The Journal of nutritional biochemistry. vol 24. issue 7. 2014-01-29. PMID:23337348. |
the aim of this study was to investigate serotonin receptor (5-ht(1a) and 5-ht2a), cannabinoid receptor (cb1) and gamma-aminobutyric acid type a (gaba(a)) receptor binding densities in the brain of male rats fed a high-saturated-fat (hf) diet, as well as the effect of dha supplementation on hf diet. |
2014-01-29 |
2023-08-12 |
rat |
| Shannon R Murphy, Edward S Schelegle, Lisa A Miller, Dallas M Hyde, Laura S Van Winkl. Ozone exposure alters serotonin and serotonin receptor expression in the developing lung. Toxicological sciences : an official journal of the Society of Toxicology. vol 134. issue 1. 2014-01-28. PMID:23570994. |
ozone exposure alters serotonin and serotonin receptor expression in the developing lung. |
2014-01-28 |
2023-08-12 |
monkey |
| Shannon R Murphy, Edward S Schelegle, Lisa A Miller, Dallas M Hyde, Laura S Van Winkl. Ozone exposure alters serotonin and serotonin receptor expression in the developing lung. Toxicological sciences : an official journal of the Society of Toxicology. vol 134. issue 1. 2014-01-28. PMID:23570994. |
ozone exposure increases serotonin in airway epithelium regardless of airway level, age, and exposure history and changes the spatial pattern of serotonin receptor protein (5-ht2a and 5-ht4) and 5-htt gene expression depending on compartment, age, and exposure history. |
2014-01-28 |
2023-08-12 |
monkey |
| T Sumiyoshi, Y Higuch. Facilitative effect of serotonin(1A) receptor agonists on cognition in patients with schizophrenia. Current medicinal chemistry. vol 20. issue 3. 2014-01-17. PMID:23157627. |
among the 5-ht receptor subtypes, the 5-ht(1a) receptor is attracting particular interests as a potential target for enhancing cognition, based on preclinical and clinical evidence. |
2014-01-17 |
2023-08-12 |
Not clear |
| Yvonne Dempsie, Margaret R Maclea. Role of the serotonin transporter in pulmonary arterial hypertension. Expert review of clinical pharmacology. vol 1. issue 6. 2014-01-14. PMID:24410605. |
research has identified changes in serotonin synthesis, serotonin receptor activation and serotonin uptake via the serotonin transporter in experimental and clinical pulmonary arterial hypertension. |
2014-01-14 |
2023-08-12 |
Not clear |
| Zoe R Donaldson, Katherine M Nautiyal, Susanne E Ahmari, René He. Genetic approaches for understanding the role of serotonin receptors in mood and behavior. Current opinion in neurobiology. vol 23. issue 3. 2014-01-06. PMID:23385115. |
this review highlights the contribution of genetic techniques to dissect the specific function of distinct serotonin receptor populations across the life course, with an emphasis on the contribution of different serotonin 1a receptor populations to mood and behavior. |
2014-01-06 |
2023-08-12 |
Not clear |
| Alice B Nongonierma, Harriët Schellekens, Timothy G Dinan, John F Cryan, Richard J FitzGeral. Milk protein hydrolysates activate 5-HT(2C) serotonin receptors: influence of the starting substrate and isolation of bioactive fractions. Food & function. vol 4. issue 5. 2014-01-02. PMID:23435627. |
in its unhydrolysed form, gmp was the only starting substrate showing 5-ht(2c) serotonin receptor agonist activity. |
2014-01-02 |
2023-08-12 |
Not clear |
| Alice B Nongonierma, Harriët Schellekens, Timothy G Dinan, John F Cryan, Richard J FitzGeral. Milk protein hydrolysates activate 5-HT(2C) serotonin receptors: influence of the starting substrate and isolation of bioactive fractions. Food & function. vol 4. issue 5. 2014-01-02. PMID:23435627. |
the 5-ht(2c) serotonin receptor agonist activity of its corresponding hydrolysate (gmph-240 min) was significantly higher (p < 0.05). |
2014-01-02 |
2023-08-12 |
Not clear |
| Changsu Han, Sheng-Min Wang, Masaki Kato, Soo-Jung Lee, Ashwin A Patkar, Prakash S Masand, Chi-Un Pa. Second-generation antipsychotics in the treatment of major depressive disorder: current evidence. Expert review of neurotherapeutics. vol 13. issue 7. 2013-12-31. PMID:23898855. |
to overcome such a serious mental disorder, we currently have a number of different classes of antidepressants, such as selective serotonin reuptake inhibitors, serotonin-norepinephrine reuptake inhibitors, noradrenergic and specific serotonin receptor antagonists, dopamine and norepinephrine reuptake inhibitors, along with newly introduced antidepressants (e.g., vilazodone and agomelatine). |
2013-12-31 |
2023-08-12 |
Not clear |
| S K Bhattacharya, S S Parma. Prostaglandin d2 induced potentiation of the anticonvulsant actions of phenobarbitone and phenytoin in rats. Role of serotonin. Pharmaceutical research. vol 2. issue 6. 2013-11-26. PMID:24271132. |
pdg2-induced potentiation of phenobarbitone and phenytoin was significantly attenuated following pretreatment with centrally administered 5,6-dihydroxytryptamine, a selective neurotoxin for serotonergic neurones, p-chlorophenylalanine, a specific inhibitor of serotonin biosynthesis, and methysergide, a serotonin receptor antagonist, indicating that the potentiation was serotonin-mediated. |
2013-11-26 |
2023-08-12 |
rat |
| S K Bhattacharya, N Da. Central Serotonergic Modulation of Carrageenin-induced Pedal Inflammation in Rats. Pharmaceutical research. vol 2. issue 6. 2013-11-26. PMID:24271133. |
metergoline, a serotonin receptor antagonist, inhibited the anti-inflammatory effect of centrally administered serotonin. |
2013-11-26 |
2023-08-12 |
rat |
| Audrey Francisco Biagioni, Renato Leonardo de Freitas, Juliana Almeida da Silva, Rithiele Cristina de Oliveira, Ricardo de Oliveira, Vani Maria Alves, Norberto Cysne Coimbr. Serotonergic neural links from the dorsal raphe nucleus modulate defensive behaviours organised by the dorsomedial hypothalamus and the elaboration of fear-induced antinociception via locus coeruleus pathways. Neuropharmacology. vol 67. 2013-11-04. PMID:23201351. |
pre-treatment with the non-selective 5-ht receptor antagonist methysergide, the 5-ht(2a/2c) receptor antagonist ketanserin and the 5-ht(2a) receptor selective antagonist r-96544 in the lc also decreased fear-induced antinociception, without significant changes in the expression of defensive behaviours. |
2013-11-04 |
2023-08-12 |
Not clear |
| Jun-Xu Li, Aparna P Shah, Sunny K Patel, Kenner C Rice, Charles P Franc. Modification of the behavioral effects of morphine in rats by serotonin 5-HT₁A and 5-HT₂A receptor agonists: antinociception, drug discrimination, and locomotor activity. Psychopharmacology. vol 225. issue 4. 2013-10-17. PMID:22993050. |
indirect-acting serotonin (5-ht) receptor agonists can enhance the antinociceptive effects of morphine; however, the specific 5-ht receptor subtype(s) mediating this enhancement is not established. |
2013-10-17 |
2023-08-12 |
rat |
| Andrea E Corcoran, George B Richerson, Michael B Harri. Serotonergic mechanisms are necessary for central respiratory chemoresponsiveness in situ. Respiratory physiology & neurobiology. vol 186. issue 2. 2013-09-20. PMID:23454177. |
this study was designed to assess the importance of 5-ht neurons and 5-ht receptor activation in the frequency and amplitude components of the hypercapnic response of the respiratory network in the unanesthetized perfused in situ juvenile rat brainstem preparation that exhibits patterns of phrenic nerve discharge similar to breathing in vivo. |
2013-09-20 |
2023-08-12 |
rat |
| Andrea E Corcoran, George B Richerson, Michael B Harri. Serotonergic mechanisms are necessary for central respiratory chemoresponsiveness in situ. Respiratory physiology & neurobiology. vol 186. issue 2. 2013-09-20. PMID:23454177. |
these data illustrate that 5-ht neurons and 5-ht receptor activation are not required for respiratory rhythm generation per se, but are critical for co2 responses in situ, supporting the hypothesis that 5-ht neurons play an important role in central ventilatory chemosensitivity in vivo. |
2013-09-20 |
2023-08-12 |
rat |